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Print ISSN: 1792-1074 Online ISSN: 1792-1082
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April-2024 Volume 27 Issue 4

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International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

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Case Report Open Access

Tumor reduction after SARS‑CoV‑2 infection in a patient with lung cancer: A case report

  • Authors:
    • Xiaoming Zhang
    • Jingyu Chen
    • Jie Sun
    • Shuyue Gao
    • Feiyu Zhao
    • Niansong Qian
  • View Affiliations / Copyright

    Affiliations: Department of Oncology, Hainan Hospital of Chinese PLA General Hospital, Sanya, Hainan 572000, P.R. China, Department of College English, School of Languages and Communication Studies, Beijing Jiaotong University, Beijing 100044, P.R. China, Department of Oncology, Fifth Medical Center of Chinese People's Liberation Army General Hospital, Beijing 100039, P.R. China, Department of Oncology, Graduate School of Chinese People's Liberation Army General Hospital, Beijing 100853, P.R. China, Department of Respiratory and Critical Care Medicine, Eighth Medical Center of Chinese People's Liberation Army General Hospital, Beijing 100091, P.R. China
    Copyright: © Zhang et al. This is an open access article distributed under the terms of Creative Commons Attribution License.
  • Article Number: 169
    |
    Published online on: February 22, 2024
       https://doi.org/10.3892/ol.2024.14302
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Abstract

Lung cancer is one of the most common malignancies worldwide. Since the global outbreak of the coronavirus disease 2019 (COVID‑19) pandemic in 2020, the impact of severe acute respiratory syndrome coronavirus 2 (SARS‑CoV‑2) on lung cancer has been extensively studied. Despite reports about SARS‑CoV‑2 infection inducing a significant increase in the number of medical visits for patients with cancer, the virus has also been reported to produce some unknown benefits. The present study reports the case of a patient with lung cancer whose tumor lesion was reduced in size after SARS‑CoV‑2 infection even though the therapeutic regimen remained unchanged. Although the mechanism involved is not yet understood, this case supports the novel idea of applying SARS‑CoV‑2 in oncolytic virotherapy.
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1 

Siegel RL, Miller KD, Wagle NS and Jemal A: Cancer statistics, 2023. CA Cancer J Clin. 73:17–48. 2023. View Article : Google Scholar : PubMed/NCBI

2 

Petty WJ and Paz-Ares L: Emerging strategies for the treatment of small cell lung cancer: A review. JAMA Oncol. 9:419–429. 2023. View Article : Google Scholar : PubMed/NCBI

3 

Vokes NI, Pan K and Le X: Efficacy of immunotherapy in oncogene-driven non-small-cell lung cancer. Ther Adv Med Oncol. 15:175883592311614092023. View Article : Google Scholar : PubMed/NCBI

4 

Zong Z, Wei Y, Ren J, Zhang L and Zhou F: The intersection of COVID-19 and cancer: Signaling pathways and treatment implications. Mol Cancer. 20:76–82. 2021. View Article : Google Scholar : PubMed/NCBI

5 

Tsamakis K, Gavriatopoulou M, Schizas D, Stravodimou A, Mougkou A, Tsiptsios D, Sioulas V, Spartalis E, Sioulas AD, Tsamakis C, et al: Oncology during the COVID-19 pandemic: Challenges, dilemmas and the psychosocial impact on cancer patients. Oncol Lett. 20:441–447. 2020. View Article : Google Scholar : PubMed/NCBI

6 

Bounassar-Filho JP, Boeckler-Troncoso L, Cajigas-Gonzalez J and Zavala-Cerna MG: SARS-CoV-2 as an oncolytic virus following reactivation of the immune system: A review. Int J Mol Sci. 24:243–249. 2023. View Article : Google Scholar : PubMed/NCBI

7 

Meo C, Palma G, Bruzzese F, Budillon A, Napoli C and de Nigris F: Spontaneous cancer remission after COVID-19: Insights from the pandemic and their relevance for cancer treatment. J Transl Med. 21:273–278. 2023. View Article : Google Scholar : PubMed/NCBI

8 

Rahimmanesh I, Shariati L, Dana N, Esmaeili Y, Vaseghi G and Haghjooy Javanmard S: Cancer occurrence as the upcoming complications of COVID-19. Front Mol Biosci. 8:8131752021. View Article : Google Scholar : PubMed/NCBI

9 

Kurlapski M, Romanowicz G, Taszner M and Zaucha JM: SARS-CoV-2-induced remission of advanced classical Hodgkin lymphoma. Pol Arch Intern Med. 13:132–139. 2022.

10 

Sollini M, Gelardi F, Carlo-Stella C and Chiti A: Complete remission of follicular lymphoma after SARS-CoV-2 infection: from the ‘flare phenomenon’ to the ‘abscopal effect’. Eur J Nucl Med Mol Imaging. 48:2652–2654. 2021. View Article : Google Scholar : PubMed/NCBI

11 

Barkhordar M, Rostami FT, Yaghmaie M, Abbaszadeh M, Chahardouli B and Mousavi SA: Spontaneous complete remission of acute myeloid leukemia in the absence of disease-modifying therapy following severe pulmonary involvement by coronavirus infectious disease-19. Case Rep Hematol. 2022:26036072022.PubMed/NCBI

12 

Bulbul H, Nazli HE, Olgun A, Togay A and Kahraman DS: Spontaneous remission of chronic lymphocytic leukemia in a patient with SARS-CoV2. Leuk Res Rep. 18:103–106. 2022.PubMed/NCBI

13 

Ottaiano A, Scala S, D'Alterio C, Trotta A, Bello A, Rea G, Picone C, Santorsola M, Petrillo A and Nasti G: Unexpected tumor reduction in metastatic colorectal cancer patients during SARS-Cov-2 infection. Ther Adv Med Oncol. 13:175883592110114552021. View Article : Google Scholar : PubMed/NCBI

14 

Ottaiano A, Santorsola M, Circelli L, Cascella M, Petrillo N, Perri F, Casillo M, Granata V, Ianniello M, Izzo F, et al: Genetic landscape of colorectal cancer patients manifesting tumor shrinkage during SARS-Cov-2 infection. Ther Adv Med Oncol. 14:175883592211383882022. View Article : Google Scholar : PubMed/NCBI

15 

Buchler T, Fiser L, Benesova J, Jirickova H and Votrubova J: Spontaneous regression of metastatic renal cell carcinoma after SARS-CoV-2 infection: A report of two cases. Curr Oncol. 28:3403–3407. 2021. View Article : Google Scholar : PubMed/NCBI

16 

Daly JL, Simonetti B, Klein K, Chen KE, Williamson MK, Anton-Plagaro C, Shoemark DK, Simon-Gracia L, Bauer M, Hollandi R, et al: Neuropilin-1 is a host factor for SARS-CoV-2 infection. Science. 370:861–865. 2020. View Article : Google Scholar : PubMed/NCBI

17 

Challenor S and Tucker D: SARS-CoV-2-induced remission of Hodgkin lymphoma. Br J Haematol. 192:415–421. 2021. View Article : Google Scholar : PubMed/NCBI

18 

Pasin F, Mascalchi Calveri M, Calabrese A, Pizzarelli G, Bongiovanni I, Andreoli M, Cattaneo C and Rignanese G: Oncolytic effect of SARS-CoV2 in a patient with NK lymphoma. Acta Biomed. 91:Aug 10–2020.(Epub ahead of print).

19 

Lin D, Shen Y and Liang T: Oncolytic virotherapy: Basic principles, recent advances and future directions. Signal Transduct Target Ther. 8:156–173. 2023. View Article : Google Scholar : PubMed/NCBI

20 

Dock G: The influence of complicating diseases upon leukemia. Am J Med Sci. 127:563–592. 1904. View Article : Google Scholar

21 

Kristin DP and Greg MD: Integrating innate and adaptive immunity in oncolytic virus therapy. Trends Cancer. 23:190–196. 2023.

22 

Yun CO, Hong J and Yoon AR: Current clinical landscape of oncolytic viruses as novel cancer immunotherapeutic and recent preclinical advancements. Front Immunol. 13:95–104. 2022. View Article : Google Scholar

23 

Muscolini M, Tassone E and Hiscott J: Oncolytic immunotherapy: Can't start a fire without a spark. Cytokine Growth Factor Rev. 56:94–101. 2020. View Article : Google Scholar : PubMed/NCBI

24 

Hamad A, Yusubalieva GM, Baklaushev VP, Chumakov PM and Lipatova AV: Recent developments in glioblastoma therapy: Oncolytic viruses and emerging future strategies. Viruses. 15:106–119. 2023. View Article : Google Scholar

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Copy and paste a formatted citation
Spandidos Publications style
Zhang X, Chen J, Sun J, Gao S, Zhao F and Qian N: Tumor reduction after SARS‑CoV‑2 infection in a patient with lung cancer: A case report. Oncol Lett 27: 169, 2024.
APA
Zhang, X., Chen, J., Sun, J., Gao, S., Zhao, F., & Qian, N. (2024). Tumor reduction after SARS‑CoV‑2 infection in a patient with lung cancer: A case report. Oncology Letters, 27, 169. https://doi.org/10.3892/ol.2024.14302
MLA
Zhang, X., Chen, J., Sun, J., Gao, S., Zhao, F., Qian, N."Tumor reduction after SARS‑CoV‑2 infection in a patient with lung cancer: A case report". Oncology Letters 27.4 (2024): 169.
Chicago
Zhang, X., Chen, J., Sun, J., Gao, S., Zhao, F., Qian, N."Tumor reduction after SARS‑CoV‑2 infection in a patient with lung cancer: A case report". Oncology Letters 27, no. 4 (2024): 169. https://doi.org/10.3892/ol.2024.14302
Copy and paste a formatted citation
x
Spandidos Publications style
Zhang X, Chen J, Sun J, Gao S, Zhao F and Qian N: Tumor reduction after SARS‑CoV‑2 infection in a patient with lung cancer: A case report. Oncol Lett 27: 169, 2024.
APA
Zhang, X., Chen, J., Sun, J., Gao, S., Zhao, F., & Qian, N. (2024). Tumor reduction after SARS‑CoV‑2 infection in a patient with lung cancer: A case report. Oncology Letters, 27, 169. https://doi.org/10.3892/ol.2024.14302
MLA
Zhang, X., Chen, J., Sun, J., Gao, S., Zhao, F., Qian, N."Tumor reduction after SARS‑CoV‑2 infection in a patient with lung cancer: A case report". Oncology Letters 27.4 (2024): 169.
Chicago
Zhang, X., Chen, J., Sun, J., Gao, S., Zhao, F., Qian, N."Tumor reduction after SARS‑CoV‑2 infection in a patient with lung cancer: A case report". Oncology Letters 27, no. 4 (2024): 169. https://doi.org/10.3892/ol.2024.14302
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