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Case Report Open Access

Simultaneous blastic plasmacytoid dendritic cell neoplasm and myelofibrosis: A case report

  • Authors:
    • Fuyi Luo
    • Bingjie Li
    • Jing Li
    • Yan Li
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    Affiliations: Graduate School, Hebei North University, Zhangjiakou, Hebei 075000, P.R. China, Department of Pathology, Hebei General Hospital, Shijiazhuang, Hebei 050000, P.R. China, Department of Hematology, Hebei Province Hospital of Chinese Medicine, Shijiazhuang, Hebei 050000, P.R. China, Department of Hematology, Hebei General Hospital, Shijiazhuang, Hebei 050000, P.R. China
    Copyright: © Luo et al. This is an open access article distributed under the terms of Creative Commons Attribution License.
  • Article Number: 220
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    Published online on: March 22, 2024
       https://doi.org/10.3892/ol.2024.14354
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Abstract

Blastic plasmacytoid dendritic cell neoplasm (BPDCN) is an extremely rare and aggressive tumor with an unknown pathogenesis. Myelofibrosis (MF) is a type of myeloproliferative neoplasm. MF can be secondary to several hematological malignancies, including chronic myeloid leukemia, myelodysplastic syndrome and hairy cell leukemia. In the present report, a rare case of BPDCN secondary to MF is described. A 70‑year‑old male patient developed a large purplish‑red rash with recurrent symptoms. BPDCN was confirmed by immunohistochemistry of a biopsy specimen and flow cytometry of bone marrow cells. Bone marrow histopathology revealed MF. Next‑generation sequencing of peripheral blood revealed mutations in the Tet methylcytosine dioxygenase 2 and NRAS proto‑oncogene GTPase genes. The patient underwent one cycle of chemoimmunotherapy, but the condition progressed, an infection developed and the patient eventually died. The present case suggests that BPDCN can occur in conjunction with MF and that the prognosis of such patients is poor. Pathological examination and genetic testing aided in the diagnosis and treatment. This case emphasizes the need to raise awareness of BPDCN among clinicians and to be alert to the potential for fatal infection in patients with BPDCN combined with MF following myelosuppression triggered during chemotherapy.
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1 

Guru Murthy GS, Pemmaraju N and Atallah E: Epidemiology and survival of blastic plasmacytoid dendritic cell neoplasm. Leuk Res. 73:21–23. 2018. View Article : Google Scholar : PubMed/NCBI

2 

Pagano L, Valentini CG, Pulsoni A, Fisogni S, Carluccio P, Mannelli F, Lunghi M, Pica G, Onida F, Cattaneo C, et al: Blastic plasmacytoid dendritic cell neoplasm with leukemic presentation: An Italian multicenter study. Haematologica. 98:239–246. 2013. View Article : Google Scholar : PubMed/NCBI

3 

Jain A and Sweet K: Blastic plasmacytoid dendritic cell neoplasm. J Natl Compr Canc Netw. 21:515–521. 2023. View Article : Google Scholar : PubMed/NCBI

4 

Garnache-Ottou F, Vidal C, Biichlé S, Renosi F, Poret E, Pagadoy M, Desmarets M, Roggy A, Seilles E, Soret L, et al: How should we diagnose and treat blastic plasmacytoid dendritic cell neoplasm patients? Blood Adv. 3:4238–4251. 2019. View Article : Google Scholar : PubMed/NCBI

5 

Khoury JD, Solary E, Abla O, Akkari Y, Alaggio R, Apperley JF, Bejar R, Berti E, Busque L, Chan JKC, et al: The 5th edition of the World Health Organization classification of haematolymphoid tumours: Myeloid and histiocytic/dendritic neoplasms. Leukemia. 36:1703–1719. 2022. View Article : Google Scholar : PubMed/NCBI

6 

Facchetti F, Cigognetti M, Fisogni S, Rossi G, Lonardi S and Vermi W: Neoplasms derived from plasmacytoid dendritic cells. Mod Pathol. 29:98–111. 2016. View Article : Google Scholar : PubMed/NCBI

7 

Pemmaraju N, Kantarjian H, Sweet K, Wang E, Senapati J, Wilson NR, Konopleva M, Frankel AE, Gupta V, Mesa R, et al: North American blastic plasmacytoid dendritic cell neoplasm consortium: Position on standards of care and areas of need. Blood. 141:567–578. 2023. View Article : Google Scholar : PubMed/NCBI

8 

Yun S, Chan O, Kerr D, Vincelette ND, Idrees A, Mo Q, Sweet K, Lancet JE, Kharfan-Dabaja MA, Zhang L and Sokol L: Survival outcomes in blastic plasmacytoid dendritic cell neoplasm by first-line treatment and stem cell transplant. Blood Adv. 4:3435–3442. 2020. View Article : Google Scholar : PubMed/NCBI

9 

Taylor J, Haddadin M, Upadhyay VA, Grussie E, Mehta-Shah N, Brunner AM, Louissaint A Jr, Lovitch SB, Dogan A, Fathi AT, et al: Multicenter analysis of outcomes in blastic plasmacytoid dendritic cell neoplasm offers a pretargeted therapy benchmark. Blood. 134:678–687. 2019. View Article : Google Scholar : PubMed/NCBI

10 

Huang L and Wang F: Primary blastic plasmacytoid dendritic cell neoplasm: A US population-based study. Front Oncol. 13:11781472023. View Article : Google Scholar : PubMed/NCBI

11 

Murthy HS, Zhang MJ, Chen K, Ahmed S, Deotare U, Ganguly S, Kansagra A, Michelis FV, Nishihori T, Patnaik M, et al: Allogeneic hematopoietic cell transplantation for blastic plasmacytoid dendritic cell neoplasm: A CIBMTR analysis. Blood Adv. 7:7007–7016. 2023. View Article : Google Scholar : PubMed/NCBI

12 

Tefferi A: Primary myelofibrosis: 2023 Update on diagnosis, risk-stratification, and management. Am J Hematol. 98:801–821. 2023. View Article : Google Scholar : PubMed/NCBI

13 

Titmarsh GJ, Duncombe AS, McMullin MF, O'Rorke M, Mesa R, De Vocht F, Horan S, Fritschi L, Clarke M and Anderson LA: How common are myeloproliferative neoplasms? A systematic review and meta-analysis. Am J Hematol. 89:581–587. 2014. View Article : Google Scholar : PubMed/NCBI

14 

Cervantes F, Dupriez B, Pereira A, Passamonti F, Reilly JT, Morra E, Vannucchi AM, Mesa RA, Demory JL, Barosi G, et al: New prognostic scoring system for primary myelofibrosis based on a study of the international working group for myelofibrosis research and treatment. Blood. 113:2895–2901. 2009. View Article : Google Scholar : PubMed/NCBI

15 

McLornan DP, Psaila B, Ewing J, Innes A, Arami S, Brady J, Butt NM, Cargo C, Cross NCP, Francis S, et al: The management of myelofibrosis: A British society for haematology guideline. Br J Haematol. 204:136–150. 2024. View Article : Google Scholar : PubMed/NCBI

16 

Tashi T, Yu J, Pandya S, Dieyi C, Scherber R and Parasuraman S: Trends in overall mortality among US veterans with primary myelofibrosis. BMC Cancer. 23:482023. View Article : Google Scholar : PubMed/NCBI

17 

Thiele J and Kvasnicka HM: Myelofibrosis-what's in a name? Consensus on definition and EUMNET grading. Pathobiology. 74:89–96. 2007. View Article : Google Scholar : PubMed/NCBI

18 

Wang N, Xu H, Li Q, Fang X, Liu J, Sui X, Zhang L, Jiang Y and Wang X: Patients of myelodysplastic syndrome with mild/moderate myelofibrosis and a monosomal karyotype are independently associated with an adverse prognosis: Long-term follow-up data. Cancer Manag Res. 12:5881–5891. 2020. View Article : Google Scholar : PubMed/NCBI

19 

Shehata M, Schwarzmeier JD, Hilgarth M, Hubmann R, Duechler M and Gisslinger H: TGF-beta1 induces bone marrow reticulin fibrosis in hairy cell leukemia. J Clin Invest. 113:676–685. 2004. View Article : Google Scholar : PubMed/NCBI

20 

Shenjere P, Chasty R, Chaturvedi A, Dennis MW, Ong A, Wiseman DH and Menasce LP: E-cadherin expression in blastic plasmacytoid dendritic cell neoplasms: An unrecognized finding and potential diagnostic pitfall. Int J Surg Pathol. 29:289–293. 2021. View Article : Google Scholar : PubMed/NCBI

21 

Arber DA, Orazi A, Hasserjian R, Thiele J, Borowitz MJ, Le Beau MM, Bloomfield CD, Cazzola M and Vardiman JW: The 2016 revision to the World Health Organization classification of myeloid neoplasms and acute leukemia. Blood. 127:2391–2405. 2016. View Article : Google Scholar : PubMed/NCBI

22 

Chen S, Zhou Y, Chen Y and Gu J: Fastp: An ultra-fast all-in-one fastq preprocessor. Bioinformatics. 34:i884–i890. 2018. View Article : Google Scholar : PubMed/NCBI

23 

Thorvaldsdóttir H, Robinson JT and Mesirov JP: Integrative genomics viewer (IGV): High-performance genomics data visualization and exploration. Brief Bioinform. 14:178–192. 2013. View Article : Google Scholar : PubMed/NCBI

24 

Talevich E, Shain AH, Botton T and Bastian BC: CNVkit: Genome-wide copy number detection and visualization from targeted DNA sequencing. PLoS Comput Biol. 12:e10048732016. View Article : Google Scholar : PubMed/NCBI

25 

Ye K, Guo L, Yang X, Lamijer EW, Raine K and Ning Z: Split-read indel and structural variant calling using pindel. Methods Mol Biol. 1833:95–105. 2018. View Article : Google Scholar : PubMed/NCBI

26 

Tung JK, Suarez CJ, Chiang T, Zehnder JL and Stehr H: Accurate detection and quantification of FLT3 internal tandem duplications in clinical hybrid capture next-generation sequencing data. J Mol Diagn. 23:1404–1413. 2021. View Article : Google Scholar : PubMed/NCBI

27 

Adachi M, Maeda K, Takekawa M, Hinoda Y, Imai K, Sugiyama S and Yachi A: High expression of CD56 (N-CAM) in a patient with cutaneous CD4-positive lymphoma. Am J Hematol. 47:278–282. 1994. View Article : Google Scholar : PubMed/NCBI

28 

Julia F, Dalle S, Duru G, Balme B, Vergier B, Ortonne N, Vignon-Pennamen MD, Costes-Martineau V, Lamant L, Dalac S, et al: Blastic plasmacytoid dendritic cell neoplasms: Clinico-immunohistochemical correlations in a series of 91 patients. Am J Surg Pathol. 38:673–680. 2014. View Article : Google Scholar : PubMed/NCBI

29 

Arber DA, Orazi A, Hasserjian RP, Borowitz MJ, Calvo KR, Kvasnicka HM, Wang SA, Bagg A, Barbui T, Branford S, et al: International consensus classification of myeloid neoplasms and acute leukemias: Integrating morphologic, clinical, and genomic data. Blood. 140:1200–1228. 2022. View Article : Google Scholar : PubMed/NCBI

30 

Kong LZ, Li J, Wang RC, Kang L, Wei Q and Li Y: Simultaneous follicular lymphoma and myelofibrosis: Report of a case with review of the literature. Onco Targets Ther. 14:4551–4559. 2021. View Article : Google Scholar : PubMed/NCBI

31 

Amel Riazat-Kesh YJR, Maraveyas A, Martin L and Tremblay D: An overlooked mimic? Autoimmune myelofibrosis-A scoping review of the literature. Eur J Haematol. 111:706–714. 2023. View Article : Google Scholar : PubMed/NCBI

32 

Beird HC, Khan M, Wang F, Alfayez M, Cai T, Zhao L, Khoury J, Futreal PA, Konopleva M and Pemmaraju N: Features of non-activation dendritic state and immune deficiency in blastic plasmacytoid dendritic cell neoplasm (BPDCN). Blood Cancer J. 9:992019. View Article : Google Scholar : PubMed/NCBI

33 

Tabata R, Tabata C, Nagai T and Yasumizu R: Follicular lymphoma with prominent fibrosis complicated by peripheral eosinophilia. Ann Hematol. 91:965–967. 2012. View Article : Google Scholar : PubMed/NCBI

34 

Scherber RM and Mesa RA: Managing myelofibrosis (MF) that ‘blasts’ through: Advancements in the treatment of relapsed/refractory and blast-phase MF. Hematology Am Soc Hematol Educ Program. 2018:118–126. 2018. View Article : Google Scholar : PubMed/NCBI

35 

Okabe S, Miyazawa K, Iguchi T, Sumi M, Takaku T, Ito Y, Ito Y, Kimura Y, Serizawa H, Mukai K and Ohyashiki K: Peripheral T-cell lymphoma together with myelofibrosis with elevated plasma transforming growth factor-beta1. Leuk Lymphoma. 46:599–602. 2005. View Article : Google Scholar : PubMed/NCBI

36 

Tsutsui M, Yasuda H, Ota Y and Komatsu N: Splenic marginal zone lymphoma with prominent myelofibrosis mimicking triple-negative primary myelofibrosis. Case Rep Oncol. 12:834–837. 2019. View Article : Google Scholar : PubMed/NCBI

37 

Matsunaga T, Takemoto N, Miyajima N, Okuda T, Nagashima H, Sato T, Terui T, Sasaki H, Ohmi N, Hirayama Y, et al: Splenic marginal zone lymphoma presenting as myelofibrosis associated with bone marrow involvement of lymphoma cells which secrete a large amount of TGF-beta. Ann Hematol. 83:322–325. 2004. View Article : Google Scholar : PubMed/NCBI

38 

Nakajima H and Kunimoto H: TET2 as an epigenetic master regulator for normal and malignant hematopoiesis. Cancer Sci. 105:1093–1099. 2014. View Article : Google Scholar : PubMed/NCBI

39 

Abdel-Wahab O, Mullally A, Hedvat C, Garcia-Manero G, Patel J, Wadleigh M, Malinge S, Yao J, Kilpivaara O, Bhat R, et al: Genetic characterization of TET1, TET2, and TET3 alterations in myeloid malignancies. Blood. 114:144–147. 2009. View Article : Google Scholar : PubMed/NCBI

40 

Delhommeau F, Dupont S, Della Valle V, James C, Trannoy S, Massé A, Kosmider O, Le Couedic JP, Robert F, Alberdi A, et al: Mutation in Tet2 in myeloid cancers. N Eng J Med. 360:2289–2301. 2009. View Article : Google Scholar

41 

Vainchenker W and Kralovics R: Genetic basis and molecular pathophysiology of classical myeloproliferative neoplasms. Blood. 129:667–679. 2017. View Article : Google Scholar : PubMed/NCBI

42 

Ostrander EL, Kramer AC, Mallaney C, Celik H, Koh WK, Fairchild J, Haussler E, Zhang CRC and Challen GA: Divergent effects of Dnmt3a and Tet2 mutations on hematopoietic progenitor cell fitness. Stem Cell Reports. 14:551–560. 2020. View Article : Google Scholar : PubMed/NCBI

43 

Schubbert S, Shannon K and Bollag G: Hyperactive Ras in developmental disorders and cancer. Nat Rev Cancer. 7:295–308. 2007. View Article : Google Scholar : PubMed/NCBI

44 

Ohguchi Y and Ohguchi H: Dis3: The enigmatic gene in multiple myeloma. Int J Mol Sci. 24:40792023. View Article : Google Scholar : PubMed/NCBI

45 

Chen XL, Hong LL, Wang KL, Liu X, Wang JL, Lei L, Xu ZY, Cheng XD and Ling ZQ: Deregulation of CSMD1 targeted by microRNA-10b drives gastric cancer progression through the NF-κB pathway. Int J Biol Sci. 15:2075–2086. 2019. View Article : Google Scholar : PubMed/NCBI

46 

Damm F, Chesnais V, Nagata Y, Yoshida K, Scourzic L, Okuno Y, Itzykson R, Sanada M, Shiraishi Y, Gelsi-Boyer V, et al: BCOR and BCORL1 mutations in myelodysplastic syndromes and related disorders. Blood. 122:3169–3177. 2013. View Article : Google Scholar : PubMed/NCBI

47 

Sportoletti P, Sorcini D and Falini B: BCOR gene alterations in hematologic diseases. Blood. 138:2455–2468. 2021. View Article : Google Scholar : PubMed/NCBI

48 

Badaat I, Mirza S, Padron E, Sallman D, Komrokji R, Song J and Hussaini MO: Concurrent mutations in other epigenetic modulators portend better prognosis in BCOR-mutated myelodysplastic syndrome. J Clin Pathol. 73:209–212. 2020. View Article : Google Scholar : PubMed/NCBI

49 

Elling C, Erben P, Walz C, Frickenhaus M, Schemionek M, Stehling M, Serve H, Cross NC, Hochhaus A, Hofmann WK, et al: Novel imatinib-sensitive PDGFRA-activating point mutations in hypereosinophilic syndrome induce growth factor independence and leukemia-like disease. Blood. 117:2935–2943. 2011. View Article : Google Scholar : PubMed/NCBI

50 

Abdulbaki R, DeRosa PA, Mobarek D, Liu ML and Nava VE: Novel PDGFRA mutation in blastic plasmacytoid dendritic cell neoplasm; possible therapeutic implications. Br J Haematol. 197:82022. View Article : Google Scholar : PubMed/NCBI

51 

Collin M and Bigley V: Human dendritic cell subsets: An update. Immunology. 154:3–20. 2018. View Article : Google Scholar : PubMed/NCBI

52 

Verstovsek S, Manshouri T, Pilling D, Bueso-Ramos CE, Newberry KJ, Prijic S, Knez L, Bozinovic K, Harris DM, Spaeth EL, et al: Role of neoplastic monocyte-derived fibrocytes in primary myelofibrosis. J Exp Med. 213:1723–1740. 2016. View Article : Google Scholar : PubMed/NCBI

53 

Tremblay D and Mascarenhas J: Next generation therapeutics for the treatment of myelofibrosis. Cells. 10:10342021. View Article : Google Scholar : PubMed/NCBI

54 

Werth VP, Furie RA, Romero-Diaz J, Navarra S, Kalunian K, van Vollenhoven RF, Nyberg F, Kaffenberger BH, Sheikh SZ, Radunovic G, et al: Trial of anti-BDCA2 antibody litifilimab for cutaneous lupus erythematosus. N Engl J Med. 387:321–331. 2022. View Article : Google Scholar : PubMed/NCBI

55 

Ceribelli M, Hou ZE, Kelly PN, Huang DW, Wright G, Ganapathi K, Evbuomwan MO, Pittaluga S, Shaffer AL, Marcucci G, et al: A druggable TCF4- and BRD4-dependent transcriptional network sustains malignancy in blastic plasmacytoid dendritic cell neoplasm. Cancer Cell. 30:764–778. 2016. View Article : Google Scholar : PubMed/NCBI

56 

Montero J, Stephansky J, Cai T, Griffin GK, Cabal-Hierro L, Togami K, Hogdal LJ, Galinsky I, Morgan EA, Aster JC, et al: Blastic Plasmacytoid dendritic cell neoplasm is dependent on BCL2 and sensitive to venetoclax. Cancer Discov. 7:156–164. 2017. View Article : Google Scholar : PubMed/NCBI

57 

Sapienza MR, Abate F, Melle F, Orecchioni S, Fuligni F, Etebari M, Tabanelli V, Laginestra MA, Pileri A, Motta G, et al: Blastic plasmacytoid dendritic cell neoplasm: Genomics mark epigenetic dysregulation as a primary therapeutic target. Haematologica. 104:729–737. 2019. View Article : Google Scholar : PubMed/NCBI

58 

Azad F, Zhang J, Miranda CJ and Gravina M: Venetoclax and Azacitidine in the treatment of blastic plasmacytoid dendritic cell neoplasm refractory to conventional therapy. Cureus. 14:e331092022.PubMed/NCBI

59 

Samhouri Y, Ursu S, Dutton N, Tanvi V and Fazal S: Tagraxofusp followed by combined azacitidine and venetoclax in blastic plasmacytoid dendritic cell neoplasm: A case report and literature review. J Oncol Pharm Pract. 27:990–995. 2021. View Article : Google Scholar : PubMed/NCBI

60 

Togami K, Pastika T, Stephansky J, Ghandi M, Christie AL, Jones KL, Johnson CA, Lindsay RW, Brooks CL, Letai A, et al: DNA methyltransferase inhibition overcomes diphthamide pathway deficiencies underlying CD123-targeted treatment resistance. J Clin Invest. 129:5005–5019. 2019. View Article : Google Scholar : PubMed/NCBI

61 

Moore AR, Rosenberg SC, McCormick F and Malek S: RAS-targeted therapies: Is the undruggable drugged? Nat Rev Drug Discov. 19:533–552. 2020. View Article : Google Scholar : PubMed/NCBI

62 

Lyman GH, Poniewierski MS and Culakova E: Risk of chemotherapy-induced neutropenic complications when treating patients with non-Hodgkin lymphoma. Expert Opin Drug Saf. 15:483–492. 2016. View Article : Google Scholar : PubMed/NCBI

63 

Dinan MA, Hirsch BR and Lyman GH: Management of chemotherapy-induced neutropenia: Measuring quality, cost, and value. J Natl Compr Canc Netw. 13:e1–e7. 2015. View Article : Google Scholar : PubMed/NCBI

64 

Epstein RS, Aapro MS, Basu Roy UK, Salimi T, Krenitsky J, Leone-Perkins ML, Girman C, Schlusser C and Crawford J: Patient burden and real-world management of chemotherapy-induced myelosuppression: Results from an online survey of patients with solid tumors. Adv Ther. 37:3606–3618. 2020. View Article : Google Scholar : PubMed/NCBI

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Copy and paste a formatted citation
Spandidos Publications style
Luo F, Li B, Li J and Li Y: Simultaneous blastic plasmacytoid dendritic cell neoplasm and myelofibrosis: A case report. Oncol Lett 27: 220, 2024.
APA
Luo, F., Li, B., Li, J., & Li, Y. (2024). Simultaneous blastic plasmacytoid dendritic cell neoplasm and myelofibrosis: A case report. Oncology Letters, 27, 220. https://doi.org/10.3892/ol.2024.14354
MLA
Luo, F., Li, B., Li, J., Li, Y."Simultaneous blastic plasmacytoid dendritic cell neoplasm and myelofibrosis: A case report". Oncology Letters 27.5 (2024): 220.
Chicago
Luo, F., Li, B., Li, J., Li, Y."Simultaneous blastic plasmacytoid dendritic cell neoplasm and myelofibrosis: A case report". Oncology Letters 27, no. 5 (2024): 220. https://doi.org/10.3892/ol.2024.14354
Copy and paste a formatted citation
x
Spandidos Publications style
Luo F, Li B, Li J and Li Y: Simultaneous blastic plasmacytoid dendritic cell neoplasm and myelofibrosis: A case report. Oncol Lett 27: 220, 2024.
APA
Luo, F., Li, B., Li, J., & Li, Y. (2024). Simultaneous blastic plasmacytoid dendritic cell neoplasm and myelofibrosis: A case report. Oncology Letters, 27, 220. https://doi.org/10.3892/ol.2024.14354
MLA
Luo, F., Li, B., Li, J., Li, Y."Simultaneous blastic plasmacytoid dendritic cell neoplasm and myelofibrosis: A case report". Oncology Letters 27.5 (2024): 220.
Chicago
Luo, F., Li, B., Li, J., Li, Y."Simultaneous blastic plasmacytoid dendritic cell neoplasm and myelofibrosis: A case report". Oncology Letters 27, no. 5 (2024): 220. https://doi.org/10.3892/ol.2024.14354
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