Spandidos Publications Logo
  • About
    • About Spandidos
    • Aims and Scopes
    • Abstracting and Indexing
    • Editorial Policies
    • Reprints and Permissions
    • Job Opportunities
    • Terms and Conditions
    • Contact
  • Journals
    • All Journals
    • Oncology Letters
      • Oncology Letters
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Oncology
      • International Journal of Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular and Clinical Oncology
      • Molecular and Clinical Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Experimental and Therapeutic Medicine
      • Experimental and Therapeutic Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Molecular Medicine
      • International Journal of Molecular Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Biomedical Reports
      • Biomedical Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Reports
      • Oncology Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular Medicine Reports
      • Molecular Medicine Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • World Academy of Sciences Journal
      • World Academy of Sciences Journal
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Functional Nutrition
      • International Journal of Functional Nutrition
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Epigenetics
      • International Journal of Epigenetics
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Medicine International
      • Medicine International
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
  • Articles
  • Information
    • Information for Authors
    • Information for Reviewers
    • Information for Librarians
    • Information for Advertisers
    • Conferences
  • Language Editing
Spandidos Publications Logo
  • About
    • About Spandidos
    • Aims and Scopes
    • Abstracting and Indexing
    • Editorial Policies
    • Reprints and Permissions
    • Job Opportunities
    • Terms and Conditions
    • Contact
  • Journals
    • All Journals
    • Biomedical Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Experimental and Therapeutic Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Epigenetics
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Functional Nutrition
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Molecular Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Medicine International
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular and Clinical Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular Medicine Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Letters
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • World Academy of Sciences Journal
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
  • Articles
  • Information
    • For Authors
    • For Reviewers
    • For Librarians
    • For Advertisers
    • Conferences
  • Language Editing
Login Register Submit
  • This site uses cookies
  • You can change your cookie settings at any time by following the instructions in our Cookie Policy. To find out more, you may read our Privacy Policy.

    I agree
Search articles by DOI, keyword, author or affiliation
Search
Advanced Search
presentation
Oncology Letters
Join Editorial Board Propose a Special Issue
Print ISSN: 1792-1074 Online ISSN: 1792-1082
Journal Cover
July-2024 Volume 28 Issue 1

Full Size Image

Sign up for eToc alerts
Recommend to Library

Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

Journal Cover
July-2024 Volume 28 Issue 1

Full Size Image

Sign up for eToc alerts
Recommend to Library

  • Article
  • Citations
    • Cite This Article
    • Download Citation
    • Create Citation Alert
    • Remove Citation Alert
    • Cited By
  • Similar Articles
    • Related Articles (in Spandidos Publications)
    • Similar Articles (Google Scholar)
    • Similar Articles (PubMed)
  • Download PDF
  • Download XML
  • View XML

  • Supplementary Files
    • Supplementary_Data.pdf
Article Open Access

Modified scoring system for the quantitative assessment of histological regression in peritoneal carcinomatosis after pressurized intraperitoneal aerosol chemotherapy: A pilot study

  • Authors:
    • Mahmoud Abbas
    • Jan Philipp Ramspott
    • Daniel Enrique Chourio Barboza
    • Andreas Pascher
    • Eva Wardelmann
    • Judith C. Sporn
  • View Affiliations / Copyright

    Affiliations: Department of Pathology, University Hospital Muenster, D-48149 Muenster, Germany, Department of General, Visceral and Transplant Surgery, University Hospital Muenster, D-48149 Muenster, Germany
    Copyright: © Abbas et al. This is an open access article distributed under the terms of Creative Commons Attribution License.
  • Article Number: 308
    |
    Published online on: May 9, 2024
       https://doi.org/10.3892/ol.2024.14441
  • Expand metrics +
Metrics: Total Views: 0 (Spandidos Publications: | PMC Statistics: )
Metrics: Total PDF Downloads: 0 (Spandidos Publications: | PMC Statistics: )
Cited By (CrossRef): 0 citations Loading Articles...

This article is mentioned in:



Abstract

Peritoneal carcinomatosis is one of the leading causes of death in patients with gastrointestinal cancer. Newer locoregional treatment concepts include pressurized intraperitoneal aerosol chemotherapy (PIPAC), the regional application of pressurized chemotherapeutic agents to the abdominal cavity, which is usually performed every 4 to 8 weeks. One of the main challenges of PIPAC therapy remains the objective assessment of treatment response. The present study describes a new scoring system to histologically assess the regression of peritoneal cancer following PIPAC therapy, quantitative assessment of histological regression in peritoneal carcinomatosis (QARP). Peritoneal biopsies from 27 patients with peritoneal metastases undergoing PIPAC were obtained and processed in a standardized fashion. Biopsies were scored according to the QARP grading system. The five‑tiered system was graded as follows, Grade 0, no residual tumor cells with regressive changes present; grade 1, 1‑25% viable tumor cells per tumor focus with regressive changes present; grade 2, 26‑50% viable tumor cells per tumor focus with regressive changes present; grade 3, 51‑75% viable tumor cells per tumor focus with few regressive changes; grade 4, >75% viable tumor cells per tumor focus with minimal or no regressive changes. Based on the new grading system, the study cohort was divided into QARP responders and QARP non‑responders following PIPAC treatment. Higher QARP scores were significantly correlated with higher PCI scores (r=0.32; P=0.007). However, no difference in overall survival was detected between QARP responders and QARP non‑responders. Further studies are required to ascertain the reproducibility and prognostic significance of QARP.
View Figures

Figure 1

Figure 2

Figure 3

Figure 4

Figure 5

Figure 6

View References

1 

Arnold M, Park JY, Camargo MC, Lunet N, Forman D and Soerjomataram I: Is gastric cancer becoming a rare disease? A global assessment of predicted incidence trends to 2035. Gut. 69:823–829. 2020. View Article : Google Scholar : PubMed/NCBI

2 

Koppe MJ, Boerman OC, Oyen WJ and Bleichrodt RP: Peritoneal carcinomatosis of colorectal origin: Incidence and current treatment strategies. Ann Surg. 243:212–222. 2006. View Article : Google Scholar : PubMed/NCBI

3 

Sugarbaker PH, Landy D and Pascal R: Intraperitoneal chemotherapy for peritoneal carcinomatosis from colonic or appendiceal cystadenocarcinoma: Rationale and results of treatment. Prog Clin Biol Res. 354B:141–170. 1990.PubMed/NCBI

4 

Khomyakov V, Ryabov A, Ivanov A, Bolotina L, Utkina A, Volchenko N and Kaprin A: Bidirectional chemotherapy in gastric cancer with peritoneal metastasis combining intravenous XELOX with intraperitoneal chemotherapy with low-dose cisplatin and Doxorubicin administered as a pressurized aerosol: An open-label, Phase-2 study (PIPAC-GA2). Pleura Peritoneum. 1:159–166. 2016. View Article : Google Scholar : PubMed/NCBI

5 

Tempfer CB, Rezniczek GA, Ende P, Solass W and Reymond MA: Pressurized Intraperitoneal Aerosol Chemotherapy with Cisplatin and Doxorubicin in Women with Peritoneal Carcinomatosis: A Cohort Study. Anticancer Res. 35:6723–6729. 2015.PubMed/NCBI

6 

Demtroder C, Solass W, Zieren J, Strumberg D, Giger-Pabst U and Reymond MA: Pressurized intraperitoneal aerosol chemotherapy with oxaliplatin in colorectal peritoneal metastasis. Colorectal Dis. 18:364–371. 2016. View Article : Google Scholar : PubMed/NCBI

7 

Alyami M, Gagniere J, Sgarbura O, Cabelguenne D, Villeneuve L, Pezet D, Quenet F, Glehen O, Bakrin N and Passot G: Multicentric initial experience with the use of the pressurized intraperitoneal aerosol chemotherapy (PIPAC) in the management of unresectable peritoneal carcinomatosis. Eur J Surg Oncol. 43:2178–2183. 2017. View Article : Google Scholar : PubMed/NCBI

8 

Khosrawipour T, Khosrawipour V and Giger-Pabst U: Pressurized intra peritoneal aerosol chemotherapy in patients suffering from peritoneal carcinomatosis of pancreatic adenocarcinoma. PLoS One. 12:e01867092017. View Article : Google Scholar : PubMed/NCBI

9 

Falkenstein TA, Gotze TO, Ouaissi M, Tempfer CB, Giger-Pabst U and Demtroder C: First clinical data of pressurized intraperitoneal aerosol chemotherapy (PIPAC) as salvage therapy for peritoneal metastatic biliary tract cancer. Anticancer Res. 38:373–378. 2018.PubMed/NCBI

10 

Horvath P, Beckert S, Struller F, Konigsrainer A and Reymond MA: Pressurized intraperitoneal aerosol chemotherapy (PIPAC) for peritoneal metastases of pancreas and biliary tract cancer. Clin Exp Metastasis. 35:635–640. 2018. View Article : Google Scholar : PubMed/NCBI

11 

Hubner M, Alyami M, Villeneuve L, Cortes-Guiral D, Nowacki M, So J and Sgarbura O; ISSPP PIPAC study groupL, : Consensus guidelines for pressurized intraperitoneal aerosol chemotherapy: Technical aspects and treatment protocols. Eur J Surg Oncol. 48:789–794. 2022. View Article : Google Scholar : PubMed/NCBI

12 

Hubner M, Teixeira Farinha H, Grass F, Wolfer A, Mathevet P, Hahnloser D and Demartines N: Feasibility and safety of pressurized intraperitoneal aerosol chemotherapy for peritoneal carcinomatosis: A retrospective cohort study. Gastroenterol Res Pract. 2017:68527492017. View Article : Google Scholar : PubMed/NCBI

13 

Reymond MA, Hu B, Garcia A, Reck T, Köckerling F, Hess J and Morel P: Feasibility of therapeutic pneumoperitoneum in a large animal model using a microvaporisator. Surg Endosc. 14:51–55. 2000. View Article : Google Scholar : PubMed/NCBI

14 

Solaß W, Hetzel A, Nadiradze G, Sagynaliev E and Reymond MA: Description of a novel approach for intraperitoneal drug delivery and the related device. Surg Endosc. 26:1849–1855. 2012. View Article : Google Scholar : PubMed/NCBI

15 

Solass W, Kerb R, Mürdter T, Giger-Pabst U, Strumberg D, Tempfer C, Zieren J, Schwab M and Reymond MA: Intraperitoneal chemotherapy of peritoneal carcinomatosis using pressurized aerosol as an alternative to liquid solution: First evidence for efficacy. Ann Surg Oncol. 21:553–559. 2014. View Article : Google Scholar : PubMed/NCBI

16 

Solass W, Herbette A, Schwarz T, Hetzel A, Sun JS, Dutreix M and Reymond MA: Therapeutic approach of human peritoneal carcinomatosis with Dbait in combination with capnoperitoneum: Proof of concept. Surg Endosc. 26:847–852. 2012. View Article : Google Scholar : PubMed/NCBI

17 

Di Giorgio A, Macri A, Ferracci F, Robella M, Visaloco M, De Manzoni G, Sammartino P, Sommariva A, Biacchi D, Roviello F, et al: 10 Years of pressurized intraperitoneal aerosol chemotherapy (PIPAC): A systematic review and meta-analysis. Cancers (Basel). 15:11252023. View Article : Google Scholar : PubMed/NCBI

18 

Daniel SK, Sun BJ and Lee B: PIPAC for Gastrointestinal Malignancies. J Clin Med. 12:67992023. View Article : Google Scholar : PubMed/NCBI

19 

Grass F, Vuagniaux A, Teixeira-Farinha H, Lehmann K, Demartines N and Hubner M: Systematic review of pressurized intraperitoneal aerosol chemotherapy for the treatment of advanced peritoneal carcinomatosis. Br J Surg. 104:669–678. 2017. View Article : Google Scholar : PubMed/NCBI

20 

Tempfer CB, Giger-Pabst U, Seebacher V, Petersen M, Dogan A and Rezniczek GA: A phase I, single-arm, open-label, dose escalation study of intraperitoneal cisplatin and doxorubicin in patients with recurrent ovarian cancer and peritoneal carcinomatosis. Gynecol Oncol. 150:23–30. 2018. View Article : Google Scholar : PubMed/NCBI

21 

Odendahl K, Solass W, Demtroder C, Giger-Pabst U, Zieren J, Tempfer C and Reymond MA: Quality of life of patients with end-stage peritoneal metastasis treated with pressurized intraperitoneal aerosol chemotherapy (PIPAC). Eur J Surg Oncol. 41:1379–1385. 2015. View Article : Google Scholar : PubMed/NCBI

22 

Nadiradze G, Giger-Pabst U, Zieren J, Strumberg D, Solass W and Reymond MA: Pressurized intraperitoneal aerosol chemotherapy (PIPAC) with low-dose cisplatin and doxorubicin in gastric peritoneal metastasis. J Gastrointest Surg. 20:367–373. 2016. View Article : Google Scholar : PubMed/NCBI

23 

Gockel I, Jansen-Winkeln B, Haase L, Rhode P, Mehdorn M, Niebisch S, Moulla Y, Lyros O, Lordick F, Schierle K, et al: Pressurized intraperitoneal aerosol chemotherapy (PIPAC) in gastric cancer patients with peritoneal metastasis (PM): Results of a single-center experience and register study. J Gastric Cancer. 18:379–391. 2018. View Article : Google Scholar : PubMed/NCBI

24 

Sgarbura O, Hubner M, Alyami M, Eveno C, Gagniere J, Pache B, Pocard M, Bakrin N and Quénet F: Oxaliplatin use in pressurized intraperitoneal aerosol chemotherapy (PIPAC) is safe and effective: A multicenter study. Eur J Surg Oncol. 45:2386–2391. 2019. View Article : Google Scholar : PubMed/NCBI

25 

Alyami M, Bonnot PE, Mercier F, Laplace N, Villeneuve L, Passot G, Bakrin N, Kepenekian V and Glehen O: Pressurized intraperitoneal aerosol chemotherapy (PIPAC) for unresectable peritoneal metastasis from gastric cancer. Eur J Surg Oncol. 47:123–127. 2021. View Article : Google Scholar : PubMed/NCBI

26 

Sugarbaker PH and Jablonski KA: Prognostic features of 51 colorectal and 130 appendiceal cancer patients with peritoneal carcinomatosis treated by cytoreductive surgery and intraperitoneal chemotherapy. Ann Surg. 221:124–132. 1995. View Article : Google Scholar : PubMed/NCBI

27 

Giger-Pabst U, Demtroder C, Falkenstein TA, Ouaissi M, Götze TO, Rezniczek GA and Tempfer CB: Pressurized intraperitoneal aerosol chemotherapy (PIPAC) for the treatment of malignant mesothelioma. BMC Cancer. 18:4422018. View Article : Google Scholar : PubMed/NCBI

28 

Harmon RL and Sugarbaker PH: Prognostic indicators in peritoneal carcinomatosis from gastrointestinal cancer. Int Semin Surg Oncol. 2:32005. View Article : Google Scholar : PubMed/NCBI

29 

Solass W, Sempoux C, Detlefsen S, Carr NJ and Bibeau F: Peritoneal sampling and histological assessment of therapeutic response in peritoneal metastasis: Proposal of the peritoneal regression grading score (PRGS). Pleura Peritoneum. 1:99–107. 2016. View Article : Google Scholar : PubMed/NCBI

30 

Hubner M, Somashekhar SP, Teixeira Farinha H, Abba J, Rao RG, Alyami M and Willaert W: Treatment response after pressurized intra peritoneal aerosol chemotherapy (PIPAC) for peritoneal metastases of colorectal originf. Ann Surg Open. 3:e2032022. View Article : Google Scholar : PubMed/NCBI

31 

Kurtz F, Struller F, Horvath P, Solass W, Bosmuller H, Königsrainer A and Reymond MA: Feasibility, safety, and efficacy of pressurized intraperitoneal aerosol chemotherapy (PIPAC) for peritoneal metastasis: A registry study. Gastroenterol Res Pract. 2018:27439852018. View Article : Google Scholar : PubMed/NCBI

32 

Mandard AM, Dalibard F, Mandard JC, Marnay J, Henry-Amar M, Petiot JF, Roussel A, Jacob JH, Segol P, Samama G, et al: Pathologic assessment of tumor regression after preoperative chemoradiotherapy of esophageal carcinoma. Clinicopathologic correlations. Cancer. 73:2680–2686. 1994. View Article : Google Scholar : PubMed/NCBI

33 

Becker K, Mueller JD, Schulmacher C, Ott K, Fink U, Busch R, Böttcher K, Siewert JR and Höfler H: Histomorphology and grading of regression in gastric carcinoma treated with neoadjuvant chemotherapy. Cancer. 98:1521–1530. 2003. View Article : Google Scholar : PubMed/NCBI

34 

Baldus SE, Monig SP, Schroder W, Metzger R, Lang S, Zirbes TK, Thiele J, Müller RP, Dienes HP, Hölscher AH and Schneider PM: Regression of oesophageal carcinomas after neoadjuvant radiochemotherapy: Criteria of the histopathological evaluation. Pathologe. 25:421–427, (In German). View Article : Google Scholar : PubMed/NCBI

35 

Dworak O, Keilholz L and Hoffmann A: Pathological features of rectal cancer after preoperative radiochemotherapy. Int J Colorectal Dis. 12:19–23. 1997. View Article : Google Scholar : PubMed/NCBI

36 

Rubbia-Brandt L, Giostra E, Brezault C, Roth AD, Andres A, Audard V, Sartoretti P, Dousset B, Majno PE, Soubrane O, et al: Importance of histological tumor response assessment in predicting the outcome in patients with colorectal liver metastases treated with neo-adjuvant chemotherapy followed by liver surgery. Ann Oncol. 18:299–304. 2007. View Article : Google Scholar : PubMed/NCBI

37 

Blazer DG III, Kishi Y, Maru DM, Kopetz S, Chun YS, Overman MJ, Fogelman D, Eng C, Chang DZ, Wang H, et al: Pathologic response to preoperative chemotherapy: A new outcome end point after resection of hepatic colorectal metastases. J Clin Oncol. 26:5344–5351. 2008. View Article : Google Scholar : PubMed/NCBI

38 

Solass W, Sempoux C, Carr NJ, Bibeau F, Neureiter D, Jäger T, Di Caterino T, Brunel C, Klieser E, Fristrup CW, et al: Reproducibility of the peritoneal regression grading score for assessment of response to therapy in peritoneal metastasis. Histopathology. 74:1014–1024. 2019. View Article : Google Scholar : PubMed/NCBI

Related Articles

  • Abstract
  • View
  • Download
  • Twitter
Copy and paste a formatted citation
Spandidos Publications style
Abbas M, Ramspott JP, Chourio Barboza DE, Pascher A, Wardelmann E and Sporn JC: Modified scoring system for the quantitative assessment of histological regression in peritoneal carcinomatosis after pressurized intraperitoneal aerosol chemotherapy: A pilot study. Oncol Lett 28: 308, 2024.
APA
Abbas, M., Ramspott, J.P., Chourio Barboza, D.E., Pascher, A., Wardelmann, E., & Sporn, J.C. (2024). Modified scoring system for the quantitative assessment of histological regression in peritoneal carcinomatosis after pressurized intraperitoneal aerosol chemotherapy: A pilot study. Oncology Letters, 28, 308. https://doi.org/10.3892/ol.2024.14441
MLA
Abbas, M., Ramspott, J. P., Chourio Barboza, D. E., Pascher, A., Wardelmann, E., Sporn, J. C."Modified scoring system for the quantitative assessment of histological regression in peritoneal carcinomatosis after pressurized intraperitoneal aerosol chemotherapy: A pilot study". Oncology Letters 28.1 (2024): 308.
Chicago
Abbas, M., Ramspott, J. P., Chourio Barboza, D. E., Pascher, A., Wardelmann, E., Sporn, J. C."Modified scoring system for the quantitative assessment of histological regression in peritoneal carcinomatosis after pressurized intraperitoneal aerosol chemotherapy: A pilot study". Oncology Letters 28, no. 1 (2024): 308. https://doi.org/10.3892/ol.2024.14441
Copy and paste a formatted citation
x
Spandidos Publications style
Abbas M, Ramspott JP, Chourio Barboza DE, Pascher A, Wardelmann E and Sporn JC: Modified scoring system for the quantitative assessment of histological regression in peritoneal carcinomatosis after pressurized intraperitoneal aerosol chemotherapy: A pilot study. Oncol Lett 28: 308, 2024.
APA
Abbas, M., Ramspott, J.P., Chourio Barboza, D.E., Pascher, A., Wardelmann, E., & Sporn, J.C. (2024). Modified scoring system for the quantitative assessment of histological regression in peritoneal carcinomatosis after pressurized intraperitoneal aerosol chemotherapy: A pilot study. Oncology Letters, 28, 308. https://doi.org/10.3892/ol.2024.14441
MLA
Abbas, M., Ramspott, J. P., Chourio Barboza, D. E., Pascher, A., Wardelmann, E., Sporn, J. C."Modified scoring system for the quantitative assessment of histological regression in peritoneal carcinomatosis after pressurized intraperitoneal aerosol chemotherapy: A pilot study". Oncology Letters 28.1 (2024): 308.
Chicago
Abbas, M., Ramspott, J. P., Chourio Barboza, D. E., Pascher, A., Wardelmann, E., Sporn, J. C."Modified scoring system for the quantitative assessment of histological regression in peritoneal carcinomatosis after pressurized intraperitoneal aerosol chemotherapy: A pilot study". Oncology Letters 28, no. 1 (2024): 308. https://doi.org/10.3892/ol.2024.14441
Follow us
  • Twitter
  • LinkedIn
  • Facebook
About
  • Spandidos Publications
  • Careers
  • Cookie Policy
  • Privacy Policy
How can we help?
  • Help
  • Live Chat
  • Contact
  • Email to our Support Team