Spandidos Publications Logo
  • About
    • About Spandidos
    • Aims and Scopes
    • Abstracting and Indexing
    • Editorial Policies
    • Reprints and Permissions
    • Job Opportunities
    • Terms and Conditions
    • Contact
  • Journals
    • All Journals
    • Oncology Letters
      • Oncology Letters
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Oncology
      • International Journal of Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular and Clinical Oncology
      • Molecular and Clinical Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Experimental and Therapeutic Medicine
      • Experimental and Therapeutic Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Molecular Medicine
      • International Journal of Molecular Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Biomedical Reports
      • Biomedical Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Reports
      • Oncology Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular Medicine Reports
      • Molecular Medicine Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • World Academy of Sciences Journal
      • World Academy of Sciences Journal
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Functional Nutrition
      • International Journal of Functional Nutrition
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Epigenetics
      • International Journal of Epigenetics
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Medicine International
      • Medicine International
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
  • Articles
  • Information
    • Information for Authors
    • Information for Reviewers
    • Information for Librarians
    • Information for Advertisers
    • Conferences
  • Language Editing
Spandidos Publications Logo
  • About
    • About Spandidos
    • Aims and Scopes
    • Abstracting and Indexing
    • Editorial Policies
    • Reprints and Permissions
    • Job Opportunities
    • Terms and Conditions
    • Contact
  • Journals
    • All Journals
    • Biomedical Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Experimental and Therapeutic Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Epigenetics
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Functional Nutrition
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Molecular Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Medicine International
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular and Clinical Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular Medicine Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Letters
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • World Academy of Sciences Journal
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
  • Articles
  • Information
    • For Authors
    • For Reviewers
    • For Librarians
    • For Advertisers
    • Conferences
  • Language Editing
Login Register Submit
  • This site uses cookies
  • You can change your cookie settings at any time by following the instructions in our Cookie Policy. To find out more, you may read our Privacy Policy.

    I agree
Search articles by DOI, keyword, author or affiliation
Search
Advanced Search
presentation
Oncology Letters
Join Editorial Board Propose a Special Issue
Print ISSN: 1792-1074 Online ISSN: 1792-1082
Journal Cover
August-2024 Volume 28 Issue 2

Full Size Image

Sign up for eToc alerts
Recommend to Library

Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

Journal Cover
August-2024 Volume 28 Issue 2

Full Size Image

Sign up for eToc alerts
Recommend to Library

  • Article
  • Citations
    • Cite This Article
    • Download Citation
    • Create Citation Alert
    • Remove Citation Alert
    • Cited By
  • Similar Articles
    • Related Articles (in Spandidos Publications)
    • Similar Articles (Google Scholar)
    • Similar Articles (PubMed)
  • Download PDF
  • Download XML
  • View XML
Case Report Open Access

Skin metastasis from ovarian cancer with somatic BRCA1 mutation: A case report and literature review

  • Authors:
    • Jingheng Zhang
    • Wenfeng He
    • Zhenhua Zhang
    • Hui Dong
    • Xiangyu Deng
    • Qinglian Wen
    • Dan Li
  • View Affiliations / Copyright

    Affiliations: Department of Oncology, Affiliated Hospital of Clinical School of Medicine, Southwest Medical University, Luzhou, Sichuan 646000, P.R. China, Department of Pathology, Affiliated Hospital of Clinical School of Medicine, Southwest Medical University, Luzhou, Sichuan 646000, P.R. China
    Copyright: © Zhang et al. This is an open access article distributed under the terms of Creative Commons Attribution License.
  • Article Number: 348
    |
    Published online on: June 3, 2024
       https://doi.org/10.3892/ol.2024.14481
  • Expand metrics +
Metrics: Total Views: 0 (Spandidos Publications: | PMC Statistics: )
Metrics: Total PDF Downloads: 0 (Spandidos Publications: | PMC Statistics: )
Cited By (CrossRef): 0 citations Loading Articles...

This article is mentioned in:



Abstract

Skin metastasis from ovarian cancer is rare, and its prognosis is poor. Effective therapeutic strategies are currently lacking, but the combination of various treatment methods shrink the tumor and relieve symptoms. The present study reports a rare case of advanced ovarian cancer with skin metastases and intestinal wall thickening, along with a BRCA1 DNA repair associated (BRCA1) mutation. After standard first‑line treatment and non‑standard second‑line treatment, the patient developed skin metastases. The patient's skin itching, pain and lesions were completely relieved after administering bevacizumab in combination with paclitaxel and carboplatin. After 4 months, skin metastases recurred along with anal distension during maintenance treatment with oral poly(ADP ribose) polymerase (PARP) inhibitors. The patient was treated again with bevacizumab combined with docetaxel, and the anal distension was significantly relieved. Angiogenesis therapy combined with chemotherapy is effective, but that the disease‑free survival time is short, and PARP inhibitor maintenance effect is limited even in cases with a BRCA1 gene mutation.
View Figures

Figure 1

Figure 2

Figure 3

Figure 4

Figure 5

Figure 6

View References

1 

Ghose A, Bolina A, Mahajan I, Raza SA, Clarke M, Pal A, Sanchez E, Rallis KS and Boussios S: Hereditary ovarian cancer: towards a cost-effective prevention strategy. Int J Environ Res Public Health. 19:120572022. View Article : Google Scholar : PubMed/NCBI

2 

Mariotto AB, Yabroff KR, Shao Y, Feuer EJ and Brown ML: Projections of the cost of cancer care in the United States: 2010–2020. J Natl Cancer Inst. 103:117–128. 2011. View Article : Google Scholar : PubMed/NCBI

3 

Duska LR and Kohn EC: The new classifications of ovarian, fallopian tube, and primary peritoneal cancer and their clinical implications. Ann Oncol. 28 (Suppl 8):viii8–viii12. 2017. View Article : Google Scholar : PubMed/NCBI

4 

Pavlidis N, Rassy E, Vermorken JB, Assi T, Kattan J, Boussios S and Smith-Gagen J: The outcome of patients with serous papillary peritoneal cancer, fallopian tube cancer, and epithelial ovarian cancer by treatment eras: 27 Years data from the SEER registry. Cancer Epidemiol. 75:1020452021. View Article : Google Scholar : PubMed/NCBI

5 

Aliyuda F, Moschetta M, Ghose A, Sofia Rallis K, Sheriff M, Sanchez E, Rassy E and Boussios S: Advances in ovarian cancer treatment beyond PARP inhibitors. Curr Cancer Drug Targets. 23:433–446. 2023. View Article : Google Scholar : PubMed/NCBI

6 

Ghose A, Gullapalli SVN, Chohan N, Bolina A, Moschetta M, Rassy E and Boussios S: Applications of proteomics in ovarian cancer: Dawn of a new era. Proteomes. 10:162022. View Article : Google Scholar : PubMed/NCBI

7 

Otsuka I: Cutaneous metastases in ovarian cancer. Cancers (Basel). 11:12922019. View Article : Google Scholar : PubMed/NCBI

8 

Zhang Z, Xu M, Sakandar A, Du X, He H, He W, Li D and Wen Q: Successful treatment of a patient with brain metastasis from ovarian cancer with BRCA wild type using niraparib: A case report and review of the literature. Front Oncol. 12:8731982022. View Article : Google Scholar : PubMed/NCBI

9 

Otsuka I and Matsuura T: Skin metastases in epithelial ovarian and fallopian tube carcinoma. Medicine (Baltimore). 96:e77982017. View Article : Google Scholar : PubMed/NCBI

10 

Kim MK, Kim SH, Lee YY, Choi CH, Kim TJ, Lee JW, Lee JH, Bae DS and Kim BG: Metastatic skin lesions on lower extremities in a patient with recurrent serous papillary ovarian carcinoma: A case report and literature review. Cancer Res Treat. 44:142–145. 2012. View Article : Google Scholar : PubMed/NCBI

11 

Sehra D, Singhal S, Bhatla N, Meena J, Singh A, Kumari R and Sharma S: 2022-RA-1602-ESGO Cutaneous metastasis in epithelial ovarian cancer: Experience from a tertiary care cancer institute. Int J Gynecol Cancer. 32 (Suppl 2):A352–A353. 2022.

12 

Kanyilmaz G, Aktan M, Koc M and Findik S: Cutaneous metastases of the synchronous primary endometrial and bilateral ovarian cancer: An infrequent presentation and literature review. Case Rep Oncol Med. 2016:45686532016.PubMed/NCBI

13 

Tharakaram S: Metastases to the skin. Int J Dermatol. 27:240–242. 1988. View Article : Google Scholar : PubMed/NCBI

14 

Huang TT, Lampert EJ, Coots C and Lee JM: Targeting the PI3K pathway and DNA damage response as a therapeutic strategy in ovarian cancer. Cancer Treat Rev. 86:1020212020. View Article : Google Scholar : PubMed/NCBI

15 

Dienstmann R, Rodon J, Serra V and Tabernero J: Picking the point of inhibition: A comparative review of PI3K/AKT/mTOR pathway inhibitors. Mol Cancer Ther. 13:1021–1031. 2014. View Article : Google Scholar : PubMed/NCBI

16 

Brownstein MH and Helwig EB: Patterns of cutaneous metastasis. Arch Dermatol. 105:862–868. 1972. View Article : Google Scholar : PubMed/NCBI

17 

Cormio G, Capotorto M, Di Vagno G, Cazzolla A, Carriero C and Selvaggi L: Skin metastases in ovarian carcinoma: A report of nine cases and a review of the literature. Gynecol Oncol. 90:682–685. 2003. View Article : Google Scholar : PubMed/NCBI

18 

Charalampidis C, Lampaki S, Zarogoulidis P, Lazaridis G, Mpaka S, Kosmidis C, Tsakiridis K, Kioumis I, Pavlidis P, Karapantzos I, et al: Fine-needle aspiration of skin metastasis in ovarian cancer-report of two cases and review of the literature. Ann Transl Med. 4:4472016. View Article : Google Scholar : PubMed/NCBI

19 

Demirci S, Yavas F, Ozsaran Z, Ozsaran A, Dikmen Y, Zekioglu O, Karabulut B and Aras AB: Palliative radiotherapy for the skin metastasis of ovarian cancer: A case report and review of the literature. Med Oncol. 27:628–631. 2010. View Article : Google Scholar : PubMed/NCBI

20 

Achimaş-Cadariu P, Vlad C, Fetica B, Zgaia A and Cainap C: Unusual skin metastasis in a patient with recurrent micropapillary serous ovarian carcinoma-a case report and review of the literature. Clujul Med. 88:237–240. 2015.PubMed/NCBI

21 

Vitner D, Amit A, Kerner H, Mayer E and Lowenstein L: Cutaneous metastases from epithelial ovarian cancer. Harefuah. 150:441–442. 4912011.(In Hebrew). PubMed/NCBI

22 

Haughney RV, Slade RJ and Brain AN: An isolated abdominal wall metastasis of ovarian carcinoma ten years after primary surgery. Eur J Gynaecol Oncol. 22:102–103. 2001.PubMed/NCBI

23 

Coco D and Leanza S: Cutaneous metastasis in ovarian cancer: Case report and literature review. Maedica (Bucur). 15:552–555. 2020.PubMed/NCBI

24 

Zylberberg B, Dormont D, Madelenat P and Daraï E: Relapse after more than 20 years of follow-up for epithelial ovarian carcinoma. Obstet Gynecol. 103:1082–1084. 2004. View Article : Google Scholar : PubMed/NCBI

25 

Oh SR, Park JW, Kwon HY and Rha SH: BRCA1-mutated ovarian cancer with skin metastasis: A case report. Obstet Gynecol Sci. 60:477–480. 2017. View Article : Google Scholar : PubMed/NCBI

26 

Shah S, Cheung A, Kutka M, Sheriff M and Boussios S: Epithelial ovarian cancer: Providing evidence of predisposition genes. Int J Environ Res Public Health. 19:81132022. View Article : Google Scholar : PubMed/NCBI

27 

Zhang S, Royer R, Li S, McLaughlin JR, Rosen B, Risch HA, Fan I, Bradley L, Shaw PA and Narod SA: Frequencies of BRCA1 and BRCA2 mutations among 1,342 unselected patients with invasive ovarian cancer. Gynecol Oncol. 121:353–357. 2011. View Article : Google Scholar : PubMed/NCBI

28 

Revythis A, Limbu A, Mikropoulos C, Ghose A, Sanchez E, Sheriff M and Boussios S: Recent insights into PARP and immuno-checkpoint inhibitors in epithelial ovarian cancer. Int J Environ Res Public Health. 19:85772022. View Article : Google Scholar : PubMed/NCBI

29 

Stewart RA, Pilié PG and Yap TA: Development of PARP and immune-checkpoint inhibitor combinations. Cancer Res. 78:6717–6725. 2018. View Article : Google Scholar : PubMed/NCBI

30 

Zhang L, Chen Y, Li F, Bao L and Liu W: Atezolizumab and bevacizumab attenuate cisplatin resistant ovarian cancer cells progression synergistically via suppressing epithelial-mesenchymal transition. Front Immunol. 10:8672019. View Article : Google Scholar : PubMed/NCBI

31 

Ding L, Kim HJ, Wang Q, Kearns M, Jiang T, Ohlson CE, Li BB, Xie S, Liu JF, Stover EH, et al: PARP inhibition elicits STING-dependent antitumor immunity in brca1-deficient ovarian cancer. Cell Rep. 25:2972–2980.e5. 2018. View Article : Google Scholar : PubMed/NCBI

32 

Palfi A, Toth A, Hanto K, Deres P, Szabados E, Szereday Z, Kulcsar G, Kalai T, Hideg K, Gallyas F Jr, et al: PARP inhibition prevents postinfarction myocardial remodeling and heart failure via the protein kinase C/glycogen synthase kinase-3beta pathway. J Mol Cell Cardiol. 41:149–159. 2006. View Article : Google Scholar : PubMed/NCBI

33 

Nero C, Ciccarone F, Pietragalla A, Duranti S, Daniele G, Salutari V, Carbone MV, Scambia G and Lorusso D: Ovarian cancer treatments strategy: Focus on PARP inhibitors and immune check point inhibitors. Cancers (Basel). 13:12982021. View Article : Google Scholar : PubMed/NCBI

34 

Traiman P, de Luca LA and Bacchi CE: An extremely large, cauliflower-type, cutaneous metastasis of ovarian cancer associated with good prognosis. Gynecol Oncol. 53:239–241. 1994. View Article : Google Scholar : PubMed/NCBI

35 

Karpate SJ, Samal SL and Jain SM: Recurrent ovarian malignancy presenting as cutaneous metastasis. Indian J Dermatol. 54:380–381. 2009. View Article : Google Scholar : PubMed/NCBI

36 

Hastings V, McEachron J and Kanis MJ: Cutaneous metastasis of PD-L1 positive ovarian carcinoma. Gynecol Oncol Rep. 33:1006072020. View Article : Google Scholar : PubMed/NCBI

37 

António AM, Alves JV, Goulão J and Bártolo E: Ovarian carcinoma presenting as cutaneous nasal metastasis. An Bras Dermatol. 91 (5 suppl 1):S101–S104. 2016. View Article : Google Scholar : PubMed/NCBI

38 

Stien S, Loget J, Soibinet P, Durlach A, Fleury C and Viguier M: Ovarian cancer revealed by mammary skin metastases and cutaneous lymphangitis. Ann Dermatol Venereol. 146:663–665. 2019.(In French). View Article : Google Scholar : PubMed/NCBI

39 

Schwartz RA: Cutaneous metastatic disease. J Am Acad Dermatol. 33:161–186. 1995. View Article : Google Scholar : PubMed/NCBI

40 

Brownstein MH and Helwig EB: Metastatic tumors of the skin. Cancer. 29:1298–1307. 1972. View Article : Google Scholar : PubMed/NCBI

41 

Prat J, D'Angelo E and Espinosa I: Ovarian carcinomas: At least five different diseases with distinct histological features and molecular genetics. Hum Pathol. 80:11–27. 2018. View Article : Google Scholar : PubMed/NCBI

42 

Thomakos N, Diakosavvas M, Machairiotis N, Fasoulakis Z, Zarogoulidis P and Rodolakis A: Rare distant metastatic disease of ovarian and peritoneal carcinomatosis: A review of the literature. Cancers (Basel). 11:10442019. View Article : Google Scholar : PubMed/NCBI

43 

Lheureux S, Gourley C, Vergote I and Oza AM: Epithelial ovarian cancer. Lancet. 393:1240–1253. 2019. View Article : Google Scholar : PubMed/NCBI

44 

Erickson BK, Conner MG and Landen CN Jr: The role of the fallopian tube in the origin of ovarian cancer. Am J Obstet Gynecol. 209:409–414. 2013. View Article : Google Scholar : PubMed/NCBI

45 

Paolucci V, Schaeff B, Schneider M and Gutt C: Tumor seeding following laparoscopy: International survey. World J Surg. 23:989–997. 1999. View Article : Google Scholar : PubMed/NCBI

46 

Leary A, Cowan R, Chi D, Kehoe S and Nankivell M: Primary surgery or neoadjuvant chemotherapy in advanced ovarian cancer: The debate continues…. Am Soc Clin Oncol Educ Book. 35:153–162. 2016. View Article : Google Scholar : PubMed/NCBI

47 

Moschetta M, Boussios S, Rassy E, Samartzis EP, Funingana G and Uccello M: Neoadjuvant treatment for newly diagnosed advanced ovarian cancer: Where do we stand and where are we going? Ann Transl Med. 8:17102020. View Article : Google Scholar : PubMed/NCBI

48 

Wiechert AC, Garrett LA, Lin G and Goodman A: Management of a skin metastasis in a patient with advanced ovarian cancer. Gynecol Oncol Case Rep. 2:124–126. 2012. View Article : Google Scholar : PubMed/NCBI

49 

Hamanishi J, Mandai M, Ikeda T, Minami M, Kawaguchi A, Murayama T, Kanai M, Mori Y, Matsumoto S, Chikuma S, et al: Safety and antitumor activity of anti-PD-1 antibody, nivolumab, in patients with platinum-resistant ovarian cancer. J Clin Oncol. 33:4015–4022. 2015. View Article : Google Scholar : PubMed/NCBI

50 

Bottoni C, Scambia G, Fagotti A and Petrillo M: The safety of bevazicumab for the treatment of ovarian cancer. Expert Opin Drug Saf. 17:1107–1113. 2018. View Article : Google Scholar : PubMed/NCBI

Related Articles

  • Abstract
  • View
  • Download
  • Twitter
Copy and paste a formatted citation
Spandidos Publications style
Zhang J, He W, Zhang Z, Dong H, Deng X, Wen Q and Li D: Skin metastasis from ovarian cancer with somatic BRCA1 mutation: A case report and literature review. Oncol Lett 28: 348, 2024.
APA
Zhang, J., He, W., Zhang, Z., Dong, H., Deng, X., Wen, Q., & Li, D. (2024). Skin metastasis from ovarian cancer with somatic BRCA1 mutation: A case report and literature review. Oncology Letters, 28, 348. https://doi.org/10.3892/ol.2024.14481
MLA
Zhang, J., He, W., Zhang, Z., Dong, H., Deng, X., Wen, Q., Li, D."Skin metastasis from ovarian cancer with somatic BRCA1 mutation: A case report and literature review". Oncology Letters 28.2 (2024): 348.
Chicago
Zhang, J., He, W., Zhang, Z., Dong, H., Deng, X., Wen, Q., Li, D."Skin metastasis from ovarian cancer with somatic BRCA1 mutation: A case report and literature review". Oncology Letters 28, no. 2 (2024): 348. https://doi.org/10.3892/ol.2024.14481
Copy and paste a formatted citation
x
Spandidos Publications style
Zhang J, He W, Zhang Z, Dong H, Deng X, Wen Q and Li D: Skin metastasis from ovarian cancer with somatic BRCA1 mutation: A case report and literature review. Oncol Lett 28: 348, 2024.
APA
Zhang, J., He, W., Zhang, Z., Dong, H., Deng, X., Wen, Q., & Li, D. (2024). Skin metastasis from ovarian cancer with somatic BRCA1 mutation: A case report and literature review. Oncology Letters, 28, 348. https://doi.org/10.3892/ol.2024.14481
MLA
Zhang, J., He, W., Zhang, Z., Dong, H., Deng, X., Wen, Q., Li, D."Skin metastasis from ovarian cancer with somatic BRCA1 mutation: A case report and literature review". Oncology Letters 28.2 (2024): 348.
Chicago
Zhang, J., He, W., Zhang, Z., Dong, H., Deng, X., Wen, Q., Li, D."Skin metastasis from ovarian cancer with somatic BRCA1 mutation: A case report and literature review". Oncology Letters 28, no. 2 (2024): 348. https://doi.org/10.3892/ol.2024.14481
Follow us
  • Twitter
  • LinkedIn
  • Facebook
About
  • Spandidos Publications
  • Careers
  • Cookie Policy
  • Privacy Policy
How can we help?
  • Help
  • Live Chat
  • Contact
  • Email to our Support Team