Treatment outcomes of elective neck dissection in intrathoracic esophageal carcinoma

Lee,Dong Hoon; Lee,Dae-Neung; Jang,Hye-Bin; Lee,Joon Kyoo; Lim,Sang Chul; Yun,Ju Sik; Na,Kook Joo

doi:10.3892/ol.2024.14519

August-2024 Volume 28 Issue 2

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August-2024 Volume 28 Issue 2

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Article Open Access

Treatment outcomes of elective neck dissection in intrathoracic esophageal carcinoma

Authors:
- Dong Hoon Lee
- Dae-Neung Lee
- Hye-Bin Jang
- Joon Kyoo Lee
- Sang Chul Lim
- Ju Sik Yun
- Kook Joo Na
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Affiliations: Department of Otolaryngology-Head and Neck Surgery, Chonnam National University Medical School and Chonnam National University Hwasun Hospital, Hwasu, Jeollanam 58128, Republic of Korea, Lung and Esophageal Cancer Clinic, Chonnam National University Medical School and Chonnam National University Hwasun Hospital, Hwasun, Jeollanam 58128, Republic of Korea

Copyright: © Lee et al. This is an open access article distributed under the terms of Creative Commons Attribution License.
Article Number: 386
|
Published online on: June 20, 2024

https://doi.org/10.3892/ol.2024.14519
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Abstract

In the present study, the outcomes of elective neck dissection in patients with intrathoracic esophageal squamous cell carcinoma were investigated. From January 2016 to December 2022, 21 patients who underwent esophagectomy and elective neck dissection (both neck level IV) for intrathoracic esophageal squamous cell carcinoma were enrolled. Of these 21 patients, 19 patients were male and 2 were female. A total of 11 patients received concurrent chemoradiotherapy (CCRT) as preoperative treatment. As a result of elective neck dissection at both neck level IV, occult neck metastasis of esophageal squamous cell carcinoma was diagnosed in 3 cases, all of which involved left neck lymph nodes. The incidence of occult neck metastasis was statistically significant in patients with preoperative CCRT, high T stage and high N stage (P<0.05). In addition, 16 out of 21 patients had been under follow-up without disease recurrence after the completion of treatment. However, 3 out of 21 patients succumbed to esophageal squamous cell carcinoma and 2 out of 21 patients were alive with stable disease of esophageal carcinoma. The follow-up period was 19.2±18.4 months. In conclusion, three-field lymph node dissection for intrathoracic esophageal squamous cell carcinoma may be necessary in patients with certain phenotypes, such that collaboration between thoracic surgeons and otolaryngologists may help reduce surgical complications.

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Journals

International Journal of Molecular Medicine

International Journal of Oncology

Molecular Medicine Reports

Oncology Reports

Experimental and Therapeutic Medicine

Oncology Letters

Biomedical Reports

Molecular and Clinical Oncology

World Academy of Sciences Journal

International Journal of Functional Nutrition

International Journal of Epigenetics

Medicine International

Treatment outcomes of elective neck dissection in intrathoracic esophageal carcinoma

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