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Case Report Open Access

Gastric granular cell tumor: A case report and literature review

  • Authors:
    • Huixi Li
    • Miao Zhang
    • Youyou Zheng
    • Hong Zhang
  • View Affiliations / Copyright

    Affiliations: Department of Pathology, People's Hospital of Putuo District, Zhoushan, Zhejiang 316000, P.R. China, Department of Gastroenterology, People's Hospital of Putuo District, Zhoushan, Zhejiang 316000, P.R. China, Department of Obstetrics and Gynecology, People's Hospital of Putuo District, Zhoushan, Zhejiang 316000, P.R. China
    Copyright: © Li et al. This is an open access article distributed under the terms of Creative Commons Attribution License.
  • Article Number: 403
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    Published online on: June 27, 2024
       https://doi.org/10.3892/ol.2024.14536
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Abstract

Granular cell tumors (GCTs) are neoplasms of uncertain histopathological etiology and therefore there are no universally accepted treatment strategies. GCTs are characterized by abundant eosinophilic granules. Since they are predominantly located in the skin and subcutaneous tissues, gastric GCTs are exceedingly rare. The present study documents the case of a 52‑year‑old man who visited the Gastroenterology Clinic of the People's Hospital of Putuo District (Zhoushan, China) due to upper abdominal fullness. Endoscopic ultrasonography revealed a well‑defined hypoechoic nodule in the submucosal layer of the stomach body. The lesion was completely excised using endoscopic submucosal dissection and the patient made a full postoperative recovery. Immunohistochemistry showed positivity for S100 and CD68, with CD34 expression surrounding the tumor cells. At telephone follow‑up until May 2024, the patient's fullness and discomfort were noted to be relieved. The characteristics of the CD34 expression pattern may serve as a novel basis for the pathological diagnosis of gastric GCTs. Endoscopic resection is a feasible option for gastric GCTs smaller than 2 cm.
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Copy and paste a formatted citation
Spandidos Publications style
Li H, Zhang M, Zheng Y and Zhang H: Gastric granular cell tumor: A case report and literature review. Oncol Lett 28: 403, 2024.
APA
Li, H., Zhang, M., Zheng, Y., & Zhang, H. (2024). Gastric granular cell tumor: A case report and literature review. Oncology Letters, 28, 403. https://doi.org/10.3892/ol.2024.14536
MLA
Li, H., Zhang, M., Zheng, Y., Zhang, H."Gastric granular cell tumor: A case report and literature review". Oncology Letters 28.3 (2024): 403.
Chicago
Li, H., Zhang, M., Zheng, Y., Zhang, H."Gastric granular cell tumor: A case report and literature review". Oncology Letters 28, no. 3 (2024): 403. https://doi.org/10.3892/ol.2024.14536
Copy and paste a formatted citation
x
Spandidos Publications style
Li H, Zhang M, Zheng Y and Zhang H: Gastric granular cell tumor: A case report and literature review. Oncol Lett 28: 403, 2024.
APA
Li, H., Zhang, M., Zheng, Y., & Zhang, H. (2024). Gastric granular cell tumor: A case report and literature review. Oncology Letters, 28, 403. https://doi.org/10.3892/ol.2024.14536
MLA
Li, H., Zhang, M., Zheng, Y., Zhang, H."Gastric granular cell tumor: A case report and literature review". Oncology Letters 28.3 (2024): 403.
Chicago
Li, H., Zhang, M., Zheng, Y., Zhang, H."Gastric granular cell tumor: A case report and literature review". Oncology Letters 28, no. 3 (2024): 403. https://doi.org/10.3892/ol.2024.14536
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