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Quality of life assessment and cost‑utility analysis of initial chemotherapy for patients with non‑Hodgkin's lymphoma: A prospective analysis

  • Authors:
    • Kazuhide Tanaka
    • Masahiro Yasuda
    • Tomoya Tachi
    • Yuta Teshigawara
    • Seiji Inoue
    • Yoko Ino
    • Junichi Kitagawa
    • Yoshihiro Noguchi
    • Tomoaki Yoshimura
    • Hitomi Teramachi
    • Senji Kasahara
  • View Affiliations / Copyright

    Affiliations: Department of Pharmacy, Gifu Municipal Hospital, Gifu, Gifu 500‑8513, Japan, Laboratory of Clinical Pharmacy, Gifu Pharmaceutical University, Gifu, Gifu 501‑1196, Japan, Department of Hematology, Gifu Municipal Hospital, Gifu, Gifu 500‑8513, Japan, Laboratory of Pharmaceutical Health Care and Promotion, Gifu Pharmaceutical University, Gifu, Gifu 500‑8513, Japan
    Copyright: © Tanaka et al. This is an open access article distributed under the terms of Creative Commons Attribution License.
  • Article Number: 430
    |
    Published online on: July 11, 2024
       https://doi.org/10.3892/ol.2024.14564
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Abstract

Chemotherapy has helped prolong survival in patients with malignant lymphoma, enhancing their quality of life (QOL). Despite the eventual decline in the QOL of patients, the impact of initial chemotherapy remains poorly understood. A prospective patient‑reported QOL survey among patients with malignant lymphoma receiving initial chemotherapy was conducted, targeting those treated at Gifu Municipal Hospital (Gifu, Japan) between January 2021 and December 2022. Surveys were conducted pre‑ and post‑chemotherapy based on the EuroQol 5 dimensions. Drug costs were calculated using official prices and analyzed from the cost payer's perspective via cost‑utility analysis. Among the 60 patients included in the present study, 28 had diffuse large B‑cell lymphoma. Cyclophosphamide, doxorubicin, vincristine, prednisolone ± rituximab therapy was the most common treatment (38 patients) and demonstrated superior cost‑effectiveness due to its lowest cost and change in utility value. Initial chemotherapy for patients with malignant lymphoma generally improved the QOL. Clinical trial registration: UMIN000042868 (registered on December 28, 2020).
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Copy and paste a formatted citation
Spandidos Publications style
Tanaka K, Yasuda M, Tachi T, Teshigawara Y, Inoue S, Ino Y, Kitagawa J, Noguchi Y, Yoshimura T, Teramachi H, Teramachi H, et al: Quality of life assessment and cost‑utility analysis of initial chemotherapy for patients with non‑Hodgkin's lymphoma: A prospective analysis. Oncol Lett 28: 430, 2024.
APA
Tanaka, K., Yasuda, M., Tachi, T., Teshigawara, Y., Inoue, S., Ino, Y. ... Kasahara, S. (2024). Quality of life assessment and cost‑utility analysis of initial chemotherapy for patients with non‑Hodgkin's lymphoma: A prospective analysis. Oncology Letters, 28, 430. https://doi.org/10.3892/ol.2024.14564
MLA
Tanaka, K., Yasuda, M., Tachi, T., Teshigawara, Y., Inoue, S., Ino, Y., Kitagawa, J., Noguchi, Y., Yoshimura, T., Teramachi, H., Kasahara, S."Quality of life assessment and cost‑utility analysis of initial chemotherapy for patients with non‑Hodgkin's lymphoma: A prospective analysis". Oncology Letters 28.3 (2024): 430.
Chicago
Tanaka, K., Yasuda, M., Tachi, T., Teshigawara, Y., Inoue, S., Ino, Y., Kitagawa, J., Noguchi, Y., Yoshimura, T., Teramachi, H., Kasahara, S."Quality of life assessment and cost‑utility analysis of initial chemotherapy for patients with non‑Hodgkin's lymphoma: A prospective analysis". Oncology Letters 28, no. 3 (2024): 430. https://doi.org/10.3892/ol.2024.14564
Copy and paste a formatted citation
x
Spandidos Publications style
Tanaka K, Yasuda M, Tachi T, Teshigawara Y, Inoue S, Ino Y, Kitagawa J, Noguchi Y, Yoshimura T, Teramachi H, Teramachi H, et al: Quality of life assessment and cost‑utility analysis of initial chemotherapy for patients with non‑Hodgkin's lymphoma: A prospective analysis. Oncol Lett 28: 430, 2024.
APA
Tanaka, K., Yasuda, M., Tachi, T., Teshigawara, Y., Inoue, S., Ino, Y. ... Kasahara, S. (2024). Quality of life assessment and cost‑utility analysis of initial chemotherapy for patients with non‑Hodgkin's lymphoma: A prospective analysis. Oncology Letters, 28, 430. https://doi.org/10.3892/ol.2024.14564
MLA
Tanaka, K., Yasuda, M., Tachi, T., Teshigawara, Y., Inoue, S., Ino, Y., Kitagawa, J., Noguchi, Y., Yoshimura, T., Teramachi, H., Kasahara, S."Quality of life assessment and cost‑utility analysis of initial chemotherapy for patients with non‑Hodgkin's lymphoma: A prospective analysis". Oncology Letters 28.3 (2024): 430.
Chicago
Tanaka, K., Yasuda, M., Tachi, T., Teshigawara, Y., Inoue, S., Ino, Y., Kitagawa, J., Noguchi, Y., Yoshimura, T., Teramachi, H., Kasahara, S."Quality of life assessment and cost‑utility analysis of initial chemotherapy for patients with non‑Hodgkin's lymphoma: A prospective analysis". Oncology Letters 28, no. 3 (2024): 430. https://doi.org/10.3892/ol.2024.14564
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