|
1
|
Bray F, Ferlay J, Soerjomataram I, Siegel
RL, Torre LA and Jemal A: Global cancer statistics 2018: GLOBOCAN
estimates of incidence and mortality worldwide for 36 cancers in
185 countries. CA Cancer J Clin. 68:394–424. 2018. View Article : Google Scholar : PubMed/NCBI
|
|
2
|
Motzer RJ, Bacik J and Mazumdar M:
Prognostic factors for survival of patients with stage IV renal
cell carcinoma: Memorial sloan-kettering cancer center experience.
Clin Cancer Res. 10:6302S–6303S. 2004. View Article : Google Scholar : PubMed/NCBI
|
|
3
|
Jonasch E, Gao J and Rathmell WK: Renal
cell carcinoma. BMJ. 349:g47972014. View Article : Google Scholar : PubMed/NCBI
|
|
4
|
Pavlova NN and Thompson CB: The emerging
hallmarks of cancer metabolism. Cell Metab. 23:27–47. 2016.
View Article : Google Scholar : PubMed/NCBI
|
|
5
|
Miranda-Galvis M and Teng Y: Targeting
Hypoxia-driven metabolic reprogramming to constrain tumor
progression and metastasis. Int J Mol Sci. 21:54872020. View Article : Google Scholar : PubMed/NCBI
|
|
6
|
Zhang Y, Chen M, Liu M, Xu Y and Wu G:
Glycolysis-related genes serve as potential prognostic biomarkers
in clear cell renal cell carcinoma. Oxid Med Cell Longev.
2021:66998082021.PubMed/NCBI
|
|
7
|
Tang B, Yan R, Zhu J, Cheng S, Kong C,
Chen W, Fang S, Wang Y, Yang Y, Qiu R, et al: Integrative analysis
of the molecular mechanisms, immunological features and
immunotherapy response of ferroptosis regulators across 33 cancer
types. Int J Biol Sci. 18:180–198. 2022. View Article : Google Scholar : PubMed/NCBI
|
|
8
|
Torti SV and Torti FM: Iron and cancer:
2020 Vision. Cancer Res. 80:5435–5448. 2020. View Article : Google Scholar : PubMed/NCBI
|
|
9
|
Dixon SJ, Lemberg KM, Lamprecht MR, Skouta
R, Zaitsev EM, Gleason CE, Patel DN, Bauer AJ, Cantley AM, Yang WS,
et al: Ferroptosis: An iron-dependent form of nonapoptotic cell
death. Cell. 149:1060–1072. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
10
|
Hao J, Chen Q, Feng Y, Jiang Q, Sun H,
Deng B, Huang X, Guan J, Chen Q, Liu X, et al: Combination
treatment with FAAH inhibitors/URB597 and ferroptosis inducers
significantly decreases the growth and metastasis of renal cell
carcinoma cells via the PI3K-AKT signaling pathway. Cell Death Dis.
14:2472023. View Article : Google Scholar : PubMed/NCBI
|
|
11
|
Reed GH, Poyner RR, Larsen TM, Wedekind JE
and Rayment I: Structural and mechanistic studies of enolase. Curr
Opin Struct Biol. 6:736–743. 1996. View Article : Google Scholar : PubMed/NCBI
|
|
12
|
Zheng Y, Wu C, Yang J, Zhao Y, Jia H, Xue
M, Xu D, Yang F, Fu D, Wang C, et al: Insulin-like growth factor
1-induced enolase 2 deacetylation by HDAC3 promotes metastasis of
pancreatic cancer. Signal Transduct Target Ther. 5:532020.
View Article : Google Scholar : PubMed/NCBI
|
|
13
|
Marangos PJ, Parma AM and Goodwin FK:
Functional properties of neuronal and glial isoenzymes of brain
enolase. J Neurochem. 31:727–732. 1978. View Article : Google Scholar : PubMed/NCBI
|
|
14
|
Liu CC, Wang H, Wang WD, Wang L, Liu WJ,
Wang JH, Geng QR and Lu Y: ENO2 promotes cell proliferation,
glycolysis, and glucocorticoid-resistance in acute lymphoblastic
leukemia. Cell Physiol Biochem. 46:1525–1535. 2018. View Article : Google Scholar : PubMed/NCBI
|
|
15
|
Huebbers CU, Adam AC, Preuss SF, Schiffer
T, Schilder S, Guntinas-Lichius O, Schmidt M, Klussmann JP and
Wiesner RJ: High glucose uptake unexpectedly is accompanied by high
levels of the mitochondrial ß-F1-ATPase subunit in head and neck
squamous cell carcinoma. Oncotarget. 6:36172–36184. 2015.
View Article : Google Scholar : PubMed/NCBI
|
|
16
|
Huang J, Yang M, Liu Z, Li X, Wang J, Fu
N, Cao T and Yang X: PPFIA4 promotes colon cancer cell
proliferation and migration by enhancing tumor glycolysis. Front
Oncol. 11:6532002021. View Article : Google Scholar : PubMed/NCBI
|
|
17
|
Liu C, Liu D, Wang F, Xie J, Liu Y, Wang
H, Rong J, Xie J, Wang J, Zeng R, et al: Identification of a
glycolysis- and lactate-related gene signature for predicting
prognosis, immune microenvironment, and drug candidates in colon
adenocarcinoma. Front Cell Dev Biol. 10:9719922022. View Article : Google Scholar : PubMed/NCBI
|
|
18
|
Lang L, Wang F, Ding Z, Zhao X, Loveless
R, Xie J, Shay C, Qiu P, Ke Y, Saba NF and Teng Y: Blockade of
glutamine-dependent cell survival augments antitumor efficacy of
CPI-613 in head and neck cancer. J Exp Clin Cancer Res. 40:3932021.
View Article : Google Scholar : PubMed/NCBI
|
|
19
|
Lv C, Yu H, Wang K, Chen C, Tang J, Han F,
Mai M, Ye K, Lai M and Zhang H: ENO2 promotes colorectal cancer
metastasis by interacting with the LncRNA CYTOR and activating
YAP1-induced EMT. Cells. 11:23632022. View Article : Google Scholar : PubMed/NCBI
|
|
20
|
Zheng S, Mo J, Zhang J and Chen Y: HIF-1α
inhibits ferroptosis and promotes malignant progression in
non-small cell lung cancer by activating the Hippo-YAP signalling
pathway. Oncol Lett. 25:902023. View Article : Google Scholar : PubMed/NCBI
|
|
21
|
Liu G, Zhou J, Piao Y, Zhao X, Zuo Y and
Ji Z: Hsa_circ_0085576 promotes clear cell renal cell carcinoma
tumorigenesis and metastasis through the miR-498/YAP1 axis. Aging
(Albany NY). 12:11530–11549. 2020. View Article : Google Scholar : PubMed/NCBI
|
|
22
|
Wang J, Zhao Z, Liu Y, Cao X, Li F, Ran H,
Cao Y and Wu C: ‘Mito-Bomb’: A novel mitochondria-targeting
nanosystem for ferroptosis-boosted sonodynamic antitumor therapy.
Drug Deliv. 29:3111–3122. 2022. View Article : Google Scholar : PubMed/NCBI
|
|
23
|
Zhang M, Zhong H, Cao T, Huang Y, Ji X,
Fan GC and Peng T: Gamma-aminobutyrate transaminase protects
against lipid overload-triggered cardiac injury in mice. Int J Mol
Sci. 23:21822022. View Article : Google Scholar : PubMed/NCBI
|
|
24
|
Huang SX, Partridge MA, Ghandhi SA,
Davidson MM, Amundson SA and Hei TK: Mitochondria-derived reactive
intermediate species mediate asbestos-induced genotoxicity and
oxidative stress-responsive signaling pathways. Environ Health
Perspect. 120:840–847. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
25
|
Doherty JR and Cleveland JL: Targeting
lactate metabolism for cancer therapeutics. J Clin Invest.
123:3685–3692. 2013. View
Article : Google Scholar : PubMed/NCBI
|
|
26
|
Liberti MV and Locasale JW: The Warburg
effect: How does it benefit cancer cells? Trends Biochem Sci.
41:211–218. 2016. View Article : Google Scholar : PubMed/NCBI
|
|
27
|
Abbaszadeh Z, Çeşmeli S and Biray Avcı Ç:
Crucial players in glycolysis: Cancer progress. Gene.
726:1441582020. View Article : Google Scholar : PubMed/NCBI
|
|
28
|
Guo Y, Liang F, Zhao F and Zhao J:
Resibufogenin suppresses tumor growth and Warburg effect through
regulating miR-143-3p/HK2 axis in breast cancer. Mol Cell Biochem.
466:103–115. 2020. View Article : Google Scholar : PubMed/NCBI
|
|
29
|
Han S, Yang S, Cai Z, Pan D, Li Z, Huang
Z, Zhang P, Zhu H, Lei L and Wang W: Anti-Warburg effect of
rosmarinic acid via miR-155 in gastric cancer cells. Drug Des Devel
Ther. 9:2695–2703. 2015.PubMed/NCBI
|
|
30
|
Zheng J, Luo J, Zeng H, Guo L and Shao G:
125I suppressed the Warburg effect viaregulating
miR-338/PFKL axis in hepatocellular carcinoma. Biomed Pharmacother.
119:1094022019. View Article : Google Scholar : PubMed/NCBI
|
|
31
|
Liu Y, Liang T, Qiu X, Ye X, Li Z, Tian B
and Yan D: Down-regulation of Nfatc1 suppresses proliferation,
migration, invasion, and Warburg effect in prostate cancer cells.
Med Sci Monit. 25:1572–1581. 2019. View Article : Google Scholar : PubMed/NCBI
|
|
32
|
Morais M, Dias F, Teixeira AL and Medeiros
R: MicroRNAs and altered metabolism of clear cell renal cell
carcinoma: Potential role as aerobic glycolysis biomarkers. Biochim
Biophys Acta Gen Subj. 1861:2175–2185. 2017. View Article : Google Scholar : PubMed/NCBI
|
|
33
|
Hakimi AA, Reznik E, Lee CH, Creighton CJ,
Brannon AR, Luna A, Aksoy BA, Liu EM, Shen R, Lee W, et al: An
integrated metabolic atlas of clear cell renal cell carcinoma.
Cancer Cell. 29:104–116. 2016. View Article : Google Scholar : PubMed/NCBI
|
|
34
|
Grønningsæter IS, Fredly HK, Gjertsen BT,
Hatfield KJ and Bruserud O: Systemic metabolomic profiling of acute
myeloid leukemia patients before and during disease-stabilizing
treatment based on all-trans retinoic acid, valproic acid, and
low-dose chemotherapy. Cells. 8:12292019. View Article : Google Scholar
|
|
35
|
Fang Z, Sun Q, Yang H and Zheng J: SDHB
suppresses the tumorigenesis and development of ccRCC by inhibiting
glycolysis. Front Oncol. 11:6394082021. View Article : Google Scholar : PubMed/NCBI
|
|
36
|
Kounelakis MG, Zervakis ME, Giakos GC,
Postma GJ, Buydens LM and Kotsiakis X: On the relevance of
glycolysis process on brain gliomas. IEEE J Biomed Health Inform.
17:128–135. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
37
|
Yeh CS, Wang JY, Chung FY, Lee SC, Huang
MY, Kuo CW, Yang MJ and Lin SR: Significance of the glycolytic
pathway and glycolysis related-genes in tumorigenesis of human
colorectal cancers. Oncol Rep. 19:81–91. 2008.PubMed/NCBI
|
|
38
|
Wang Q, Chen C, Ding Q, Zhao Y, Wang Z,
Chen J, Jiang Z, Zhang Y, Xu G, Zhang J, et al: METTL3-mediated
m6A modification of HDGF mRNA promotes gastric cancer
progression and has prognostic significance. Gut. 69:1193–1205.
2020. View Article : Google Scholar : PubMed/NCBI
|
|
39
|
Sanders E and Diehl S: Analysis and
interpretation of transcriptomic data obtained from extended
Warburg effect genes in patients with clear cell renal cell
carcinoma. Oncoscience. 2:151–186. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
40
|
Teng PN, Hood BL, Sun M, Dhir R and
Conrads TP: Differential proteomic analysis of renal cell carcinoma
tissue interstitial fluid. J Proteome Res. 10:1333–1342. 2011.
View Article : Google Scholar : PubMed/NCBI
|
|
41
|
Rasmuson T, Grankvist K and Ljungberg B:
Serum gamma-enolase and prognosis of patients with renal cell
carcinoma. Cancer. 72:1324–1328. 1993. View Article : Google Scholar : PubMed/NCBI
|
|
42
|
Takashi M, Sakata T and Kato K: Use of
serum gamma-enolase and aldolase A in combination as markers for
renal cell carcinoma. Jpn J Cancer Res. 84:304–309. 1993.
View Article : Google Scholar : PubMed/NCBI
|
|
43
|
Qiu Y, Cao Y, Cao W, Jia Y and Lu N: The
application of ferroptosis in diseases. Pharmacol Res.
159:1049192020. View Article : Google Scholar : PubMed/NCBI
|
|
44
|
Li Y, Feng D, Wang Z, Zhao Y, Sun R, Tian
D, Liu D, Zhang F, Ning S, Yao J and Tian X: Ischemia-induced ACSL4
activation contributes to ferroptosis-mediated tissue injury in
intestinal ischemia/reperfusion. Cell Death Differ. 26:2284–2299.
2019. View Article : Google Scholar : PubMed/NCBI
|
|
45
|
Zou Y, Henry WS, Ricq EL, Graham ET,
Phadnis VV, Maretich P, Paradkar S, Boehnke N, Deik AA, Reinhardt
F, et al: Plasticity of ether lipids promotes ferroptosis
susceptibility and evasion. Nature. 585:603–608. 2020. View Article : Google Scholar : PubMed/NCBI
|
|
46
|
Wang J, Yin X, He W, Xue W, Zhang J and
Huang Y: SUV39H1 deficiency suppresses clear cell renal cell
carcinoma growth by inducing ferroptosis. Acta Pharm Sin B.
11:406–419. 2021. View Article : Google Scholar : PubMed/NCBI
|
|
47
|
Kumfu S, Chattipakorn S, Fucharoen S and
Chattipakorn N: Mitochondrial calcium uniporter blocker prevents
cardiac mitochondrial dysfunction induced by iron overload in
thalassemic mice. Biometals. 25:1167–1175. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
48
|
Fang X, Wang H, Han D, Xie E, Yang X, Wei
J, Gu S, Gao F, Zhu N, Yin X, et al: Ferroptosis as a target for
protection against cardiomyopathy. Proc Natl Acad Sci USA.
116:2672–2680. 2019. View Article : Google Scholar : PubMed/NCBI
|
|
49
|
She H, Tan L, Du Y, Zhou Y, Guo N, Zhang
J, Du Y, Wang Y, Wu Z, Ma C, et al: VDAC2 malonylation participates
in sepsis-induced myocardial dysfunction via mitochondrial-related
ferroptosis. Int J Biol Sci. 19:3143–3158. 2023. View Article : Google Scholar : PubMed/NCBI
|
|
50
|
Anastasiou D, Yu Y, Israelsen WJ, Jiang
JK, Boxer MB, Hong BS, Tempel W, Dimov S, Shen M, Jha A, et al:
Pyruvate kinase M2 activators promote tetramer formation and
suppress tumorigenesis. Nat Chem Biol. 8:839–847. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
51
|
Yang L, Xie M, Yang M, Yu Y, Zhu S, Hou W,
Kang R, Lotze MT, Billiar TR, Wang H, et al: PKM2 regulates the
Warburg effect and promotes HMGB1 release in sepsis. Nat Commun.
5:44362014. View Article : Google Scholar : PubMed/NCBI
|
|
52
|
Rao J, Wang H, Ni M, Wang Z, Wang Z, Wei
S, Liu M, Wang P, Qiu J, Zhang L, et al: FSTL1 promotes liver
fibrosis by reprogramming macrophage function through modulating
the intracellular function of PKM2. Gut. 71:2539–2550. 2022.
View Article : Google Scholar : PubMed/NCBI
|
|
53
|
Zhou X, Xie F, Wang L, Zhang L, Zhang S,
Fang M and Zhou F: The function and clinical application of
extracellular vesicles in innate immune regulation. Cell Mol
Immunol. 17:323–334. 2020. View Article : Google Scholar : PubMed/NCBI
|
