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Case Report Open Access

Early recurrence and extensive retroperitoneal metastasis after surgery for high‑grade mucinous tubular and spindle cell carcinoma: A case report and literature review

  • Authors:
    • Xiaofeng Ma
    • Jin Xu
    • Xinhan Ye
    • Fangjia Yang
    • Zhong Wang
    • Jianju Feng
  • View Affiliations / Copyright

    Affiliations: Department of Radiology, Zhuji People's Hospital, Zhuji, Zhejiang 311800, P.R. China
    Copyright: © Ma et al. This is an open access article distributed under the terms of Creative Commons Attribution License.
  • Article Number: 467
    |
    Published online on: July 31, 2024
       https://doi.org/10.3892/ol.2024.14600
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Abstract

Mucinous tubular and spindle cell carcinoma (MTSCC) is a rare subtype of renal cancer. The present report details the treatment experience of a case of MTSCC, where the patient underwent a right‑side laparoscopic nephrectomy in October 2020 at Zhuji People's Hospital (Zhuji, China). A total of 3 months post‑operation, multiple metastases were discovered in the right renal area and retroperitoneum, with rapid disease progression observed in the subsequent 2 months. Treatment with tislelizumab combined with pazopanib was ineffective, and the patient subsequently died. Although MTSCC is generally considered a low‑grade ‘indolent’ tumor, with most patients achieving long‑term survival post‑surgery, a minority of cases, especially those of a higher grade, may experience postoperative recurrence and metastasis. Due to the rarity of metastatic MTSCC, most studies are based on small sample sizes or case reports, and there is a lack of standardized systemic treatment and follow‑up strategies for metastatic MTSCC. The present paper summarizes and analyzes the clinical features, treatment methods and prognosis of metastatic MTSCC cases reported in the literature, aiming to provide assistance for the treatment and follow‑up management of metastatic MTSCC. Even in cases of distant metastasis, aggressive surgical treatment, metastasectomy combined with molecular targeted or immunotherapy, may still be recommended.
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Copy and paste a formatted citation
Spandidos Publications style
Ma X, Xu J, Ye X, Yang F, Wang Z and Feng J: Early recurrence and extensive retroperitoneal metastasis after surgery for high‑grade mucinous tubular and spindle cell carcinoma: A case report and literature review. Oncol Lett 28: 467, 2024.
APA
Ma, X., Xu, J., Ye, X., Yang, F., Wang, Z., & Feng, J. (2024). Early recurrence and extensive retroperitoneal metastasis after surgery for high‑grade mucinous tubular and spindle cell carcinoma: A case report and literature review. Oncology Letters, 28, 467. https://doi.org/10.3892/ol.2024.14600
MLA
Ma, X., Xu, J., Ye, X., Yang, F., Wang, Z., Feng, J."Early recurrence and extensive retroperitoneal metastasis after surgery for high‑grade mucinous tubular and spindle cell carcinoma: A case report and literature review". Oncology Letters 28.4 (2024): 467.
Chicago
Ma, X., Xu, J., Ye, X., Yang, F., Wang, Z., Feng, J."Early recurrence and extensive retroperitoneal metastasis after surgery for high‑grade mucinous tubular and spindle cell carcinoma: A case report and literature review". Oncology Letters 28, no. 4 (2024): 467. https://doi.org/10.3892/ol.2024.14600
Copy and paste a formatted citation
x
Spandidos Publications style
Ma X, Xu J, Ye X, Yang F, Wang Z and Feng J: Early recurrence and extensive retroperitoneal metastasis after surgery for high‑grade mucinous tubular and spindle cell carcinoma: A case report and literature review. Oncol Lett 28: 467, 2024.
APA
Ma, X., Xu, J., Ye, X., Yang, F., Wang, Z., & Feng, J. (2024). Early recurrence and extensive retroperitoneal metastasis after surgery for high‑grade mucinous tubular and spindle cell carcinoma: A case report and literature review. Oncology Letters, 28, 467. https://doi.org/10.3892/ol.2024.14600
MLA
Ma, X., Xu, J., Ye, X., Yang, F., Wang, Z., Feng, J."Early recurrence and extensive retroperitoneal metastasis after surgery for high‑grade mucinous tubular and spindle cell carcinoma: A case report and literature review". Oncology Letters 28.4 (2024): 467.
Chicago
Ma, X., Xu, J., Ye, X., Yang, F., Wang, Z., Feng, J."Early recurrence and extensive retroperitoneal metastasis after surgery for high‑grade mucinous tubular and spindle cell carcinoma: A case report and literature review". Oncology Letters 28, no. 4 (2024): 467. https://doi.org/10.3892/ol.2024.14600
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