Spandidos Publications Logo
  • About
    • About Spandidos
    • Aims and Scopes
    • Abstracting and Indexing
    • Editorial Policies
    • Reprints and Permissions
    • Job Opportunities
    • Terms and Conditions
    • Contact
  • Journals
    • All Journals
    • Oncology Letters
      • Oncology Letters
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Oncology
      • International Journal of Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular and Clinical Oncology
      • Molecular and Clinical Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Experimental and Therapeutic Medicine
      • Experimental and Therapeutic Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Molecular Medicine
      • International Journal of Molecular Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Biomedical Reports
      • Biomedical Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Reports
      • Oncology Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular Medicine Reports
      • Molecular Medicine Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • World Academy of Sciences Journal
      • World Academy of Sciences Journal
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Functional Nutrition
      • International Journal of Functional Nutrition
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Epigenetics
      • International Journal of Epigenetics
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Medicine International
      • Medicine International
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
  • Articles
  • Information
    • Information for Authors
    • Information for Reviewers
    • Information for Librarians
    • Information for Advertisers
    • Conferences
  • Language Editing
Spandidos Publications Logo
  • About
    • About Spandidos
    • Aims and Scopes
    • Abstracting and Indexing
    • Editorial Policies
    • Reprints and Permissions
    • Job Opportunities
    • Terms and Conditions
    • Contact
  • Journals
    • All Journals
    • Biomedical Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Experimental and Therapeutic Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Epigenetics
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Functional Nutrition
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Molecular Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Medicine International
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular and Clinical Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular Medicine Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Letters
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • World Academy of Sciences Journal
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
  • Articles
  • Information
    • For Authors
    • For Reviewers
    • For Librarians
    • For Advertisers
    • Conferences
  • Language Editing
Login Register Submit
  • This site uses cookies
  • You can change your cookie settings at any time by following the instructions in our Cookie Policy. To find out more, you may read our Privacy Policy.

    I agree
Search articles by DOI, keyword, author or affiliation
Search
Advanced Search
presentation
Oncology Letters
Join Editorial Board Propose a Special Issue
Print ISSN: 1792-1074 Online ISSN: 1792-1082
Journal Cover
November-2024 Volume 28 Issue 5

Full Size Image

Sign up for eToc alerts
Recommend to Library

Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

Journal Cover
November-2024 Volume 28 Issue 5

Full Size Image

Sign up for eToc alerts
Recommend to Library

  • Article
  • Citations
    • Cite This Article
    • Download Citation
    • Create Citation Alert
    • Remove Citation Alert
    • Cited By
  • Similar Articles
    • Related Articles (in Spandidos Publications)
    • Similar Articles (Google Scholar)
    • Similar Articles (PubMed)
  • Download PDF
  • Download XML
  • View XML

  • Supplementary Files
    • Supplementary_Data.pdf
Case Report Open Access

Effective treatment of collecting duct carcinoma in a recipient of a kidney transplant: A case report

  • Authors:
    • Tabata Carolina Faria Nascimento De Assis
    • Liane Rapatoni
    • Flavio Nogueira Segato
    • Barbhara Thais Maciel Pontes
    • Valdair Francisco Muglia
    • Miguel Moyses Neto
    • Elen Almeida Romao
  • View Affiliations / Copyright

    Affiliations: Division of Nephrology, Department of Internal Medicine, Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, São Paulo 14048‑900, Brazil, Division of Clinical Oncology, Department of Medical Imaging, Haematology and Clinical Oncology, Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, São Paulo 14048‑900, Brazil, Division of Medical Imaging, Department of Medical Imaging, Haematology and Clinical Oncology, Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, São Paulo 14048‑900, Brazil
    Copyright: © Nascimento De Assis et al. This is an open access article distributed under the terms of Creative Commons Attribution License.
  • Article Number: 528
    |
    Published online on: September 3, 2024
       https://doi.org/10.3892/ol.2024.14661
  • Expand metrics +
Metrics: Total Views: 0 (Spandidos Publications: | PMC Statistics: )
Metrics: Total PDF Downloads: 0 (Spandidos Publications: | PMC Statistics: )
Cited By (CrossRef): 0 citations Loading Articles...

This article is mentioned in:



Abstract

Collecting duct carcinoma (CDC) is a rare disease associated with a high mortality rate. The present study describes the case of a recipient of a kidney transplant with metastatic allograft CDC whose treatment was successful. The patient underwent nephrectomy, and chemotherapy with gemcitabine and cisplatin, while undergoing haemodialysis treatment and remained in remission after 6 years of follow‑up. There is a lack of information about the treatment and clinical management of CDC; however, the combination of gemcitabine and cisplatin remains as first‑line therapy. The challenge of this case was integrating chemotherapy sessions with dialysis therapy to maintain the effectiveness, tolerability and safety of the oncological treatment. In the present case report, the success of chemotherapy with gemcitabine and cisplatin was demonstrated in a metastatic renal allograft CDC in a patient with end‑stage renal disease, with few side effects and no recurrence of the disease 6 years after the end of treatment.
View Figures

Figure 1

Figure 2

Figure 3

View References

1 

Mennitto A, Verzoni E, Peverelli G, Alessi A and Procopio G: Management of metastatic collecting duct carcinoma: An encouraging result in a patient treated with cabozantinib. Clin Genitourin Cancer. 16:e521–e523. 2018. View Article : Google Scholar : PubMed/NCBI

2 

Orsola A, Trias I, Raventós CX, Español I, Cecchini L and Orsola I: Renal collecting (Bellini) duct carcinoma displays similar characteristics to upper tract urothelial cell carcinoma. Urology. 65:49–54. 2005. View Article : Google Scholar : PubMed/NCBI

3 

Oudard S, Banu E, Vieillefond A, Fournier L, Priou F, Medioni J, Banu A, Duclos B, Rolland F, Escudier B, et al: Prospective multicenter phase II study of gemcitabine plus platinum salt for metastatic collecting duct carcinoma: Results of a GETUG (Groupe d'Etudes des Tumeurs Uro-Génitales) study. J Urol. 177:1698–1702. 2007. View Article : Google Scholar : PubMed/NCBI

4 

Yin M, Wang W, Rosenberg J, Kaag M, Joshi M, Holder S, Tuanquin L and Drabick JJ: Targeted therapy in collecting duct carcinoma of the kidney: A case report and literature review. Clin Genitourin Cancer. 14:e203–e236. 2016. View Article : Google Scholar : PubMed/NCBI

5 

Suarez C, Marmolejo D, Valdivia A, Morales-Barrera R, Gonzalez M, Mateo J, Semidey ME, Lorente D, Trilla E and Carles J: Update in collecting duct carcinoma: Current aspects of the clinical and molecular characterization of an orphan disease. Front Oncol. 12:9701992022. View Article : Google Scholar : PubMed/NCBI

6 

Pepek J, Johnstone P and Jani A: Influence of demographic factors on outcome of collecting duct carcinoma: A surveillance, epidemiology, and end results (SEER) database analysis. Clin Genitourin Cancer. 7:E24–E27. 2009. View Article : Google Scholar : PubMed/NCBI

7 

Chapman JR: The KDIGO clinical practice guidelines for the care of kidney transplant recipients. Transplantation. 89:644–645. 2010. View Article : Google Scholar : PubMed/NCBI

8 

Truong LD and Shen SS: Immunohistochemical diagnosis of renal neoplasms. Arch Pathol Lab Med. 135:92–109. 2011. View Article : Google Scholar : PubMed/NCBI

9 

Carvalho JC, Thomas DG, Mchugh JB, Shah RB and Kunju LP: P63, CK7, PAX8 and INI-1: An optimal immunohistochemical panel to distinguish poorly differentiated urothelial cell carcinoma from high-grade tumours of the renal collecting system. Histopathology. 60:597–608. 2012. View Article : Google Scholar : PubMed/NCBI

10 

Rini B, McKiernan J and Chang S: Kidney. Amin M: AJCC Cancer Staging Manual. 8th edition. New York: Springer; pp. pp7392017

11 

U.S. Department of Health and Human Services, . Common Terminology Criteria for Adverse Events (CTCAE) Version 5.0. November 27–2017.

12 

Rimar KJ, Meeks JJ and Kuzel TM: Anti-programmed death receptor 1 blockade induces clinical response in a patient with metastatic collecting duct carcinoma. Clin Genitourin Cancer. 14:e431–e434. 2016. View Article : Google Scholar : PubMed/NCBI

13 

Ezaki T, Matsumoto K, Morita S, Shinoda K, Mizuno R, Kikuchi E and Oya M: A case of gemcitabine and cisplatin chemotherapy in a patient with metastatic urothelial carcinoma receiving hemodialysis. Clin Genitourin Cancer. 14:e413–e416. 2016. View Article : Google Scholar : PubMed/NCBI

14 

Chang PY, Dai MS, Ho CL and Yao NS: Administration of gemcitabine and cisplatin in cancer patients with renal failure under hemodialysis. J BUON. 18:1058–1061. 2013.PubMed/NCBI

15 

Kiani A, Köhne CH, Franz T, Passauer J, Haufe T, Gross P, Ehninger G and Schleyer E: Pharmacokinetics of gemcitabine in a patient with end-stage renal disease: Effective clearance of its main metabolite by standard hemodialysis treatment. Cancer Chemother Pharmacol. 51:266–270. 2003. View Article : Google Scholar : PubMed/NCBI

16 

Masumori N, Kunishima Y, Hirobe M, Takeuchi M, Takayanagi A, Tsukamoto T and Itoh T: Measurement of plasma concentration of gemcitabine and its metabolite dFdU in hemodialysis patients with advanced urothelial cancer. Jpn J Clin Oncol. 38:182–185. 2008. View Article : Google Scholar : PubMed/NCBI

17 

Janus N, Thariat J, Boulanger H, Deray G and Launay-Vacher V: Proposal for dosage adjustment and timing of chemotherapy in hemodialyzed patients. Ann Oncol. 21:1395–403. 2010. View Article : Google Scholar : PubMed/NCBI

18 

Zahra MA, Taylor A, Mould G, Coles C, Crawford R and Tan LT: Concurrent weekly cisplatin chemotherapy and radiotherapy in a haemodialysis patient with locally advanced cervix cancer. Clin Oncol. 20:6–11. 2008. View Article : Google Scholar

19 

Horie S, Oya M, Nangaku M, Yasuda Y, Komatsu Y, Yanagita M, Kitagawa Y, Kuwano H, Nishiyama H, Ishioka C, et al: Guidelines for treatment of renal injury during cancer chemotherapy 2016. Clin Exp Nephrol. 22:210–244. 2018. View Article : Google Scholar : PubMed/NCBI

Related Articles

  • Abstract
  • View
  • Download
  • Twitter
Copy and paste a formatted citation
Spandidos Publications style
Nascimento De Assis TF, Rapatoni L, Segato FN, Pontes BT, Muglia VF, Neto MM and Romao EA: Effective treatment of collecting duct carcinoma in a recipient of a kidney transplant: A case report. Oncol Lett 28: 528, 2024.
APA
Nascimento De Assis, T.F., Rapatoni, L., Segato, F.N., Pontes, B.T., Muglia, V.F., Neto, M.M., & Romao, E.A. (2024). Effective treatment of collecting duct carcinoma in a recipient of a kidney transplant: A case report. Oncology Letters, 28, 528. https://doi.org/10.3892/ol.2024.14661
MLA
Nascimento De Assis, T. F., Rapatoni, L., Segato, F. N., Pontes, B. T., Muglia, V. F., Neto, M. M., Romao, E. A."Effective treatment of collecting duct carcinoma in a recipient of a kidney transplant: A case report". Oncology Letters 28.5 (2024): 528.
Chicago
Nascimento De Assis, T. F., Rapatoni, L., Segato, F. N., Pontes, B. T., Muglia, V. F., Neto, M. M., Romao, E. A."Effective treatment of collecting duct carcinoma in a recipient of a kidney transplant: A case report". Oncology Letters 28, no. 5 (2024): 528. https://doi.org/10.3892/ol.2024.14661
Copy and paste a formatted citation
x
Spandidos Publications style
Nascimento De Assis TF, Rapatoni L, Segato FN, Pontes BT, Muglia VF, Neto MM and Romao EA: Effective treatment of collecting duct carcinoma in a recipient of a kidney transplant: A case report. Oncol Lett 28: 528, 2024.
APA
Nascimento De Assis, T.F., Rapatoni, L., Segato, F.N., Pontes, B.T., Muglia, V.F., Neto, M.M., & Romao, E.A. (2024). Effective treatment of collecting duct carcinoma in a recipient of a kidney transplant: A case report. Oncology Letters, 28, 528. https://doi.org/10.3892/ol.2024.14661
MLA
Nascimento De Assis, T. F., Rapatoni, L., Segato, F. N., Pontes, B. T., Muglia, V. F., Neto, M. M., Romao, E. A."Effective treatment of collecting duct carcinoma in a recipient of a kidney transplant: A case report". Oncology Letters 28.5 (2024): 528.
Chicago
Nascimento De Assis, T. F., Rapatoni, L., Segato, F. N., Pontes, B. T., Muglia, V. F., Neto, M. M., Romao, E. A."Effective treatment of collecting duct carcinoma in a recipient of a kidney transplant: A case report". Oncology Letters 28, no. 5 (2024): 528. https://doi.org/10.3892/ol.2024.14661
Follow us
  • Twitter
  • LinkedIn
  • Facebook
About
  • Spandidos Publications
  • Careers
  • Cookie Policy
  • Privacy Policy
How can we help?
  • Help
  • Live Chat
  • Contact
  • Email to our Support Team