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Case Report Open Access

Primary neuroendocrine tumor of the breast: A case report

  • Authors:
    • Husileng Ju
    • Ming Liu
  • View Affiliations / Copyright

    Affiliations: Department of Thyroid and Breast Surgery, The Affiliated Hospital of Inner Mongolia Medical University, Hohhot, Inner Mongolia Autonomous Region 010059, P.R. China
    Copyright: © Ju et al. This is an open access article distributed under the terms of Creative Commons Attribution License.
  • Article Number: 79
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    Published online on: November 27, 2024
       https://doi.org/10.3892/ol.2024.14825
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Abstract

Primary neuroendocrine neoplasm of the breast (PNENB) is a rare subtype of breast cancer, accounting for <1% of all breast tumors. The morphological features of PNENB are similar to those of neuroendocrine tumors originating in the lungs or gastrointestinal system, with tumor cells exhibiting the strong expression of neuroendocrine markers, including chromogranin A and synaptophysin. Since this type of cancer was first reported, the definition, classification and diagnostic criteria of PNENB have evolved and changed. However, accurate diagnostic criteria and standard treatment guidelines are lacking. The present report describes a specific case of PNENB, which was consistent with the morphological and molecular features of other cases in most previous studies. In addition, the current body of literature on PNENB, including its development, diagnosis, molecular features, treatment and prognosis is reviewed.
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Copy and paste a formatted citation
Spandidos Publications style
Ju H and Liu M: Primary neuroendocrine tumor of the breast: A case report. Oncol Lett 29: 79, 2025.
APA
Ju, H., & Liu, M. (2025). Primary neuroendocrine tumor of the breast: A case report. Oncology Letters, 29, 79. https://doi.org/10.3892/ol.2024.14825
MLA
Ju, H., Liu, M."Primary neuroendocrine tumor of the breast: A case report". Oncology Letters 29.2 (2025): 79.
Chicago
Ju, H., Liu, M."Primary neuroendocrine tumor of the breast: A case report". Oncology Letters 29, no. 2 (2025): 79. https://doi.org/10.3892/ol.2024.14825
Copy and paste a formatted citation
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Spandidos Publications style
Ju H and Liu M: Primary neuroendocrine tumor of the breast: A case report. Oncol Lett 29: 79, 2025.
APA
Ju, H., & Liu, M. (2025). Primary neuroendocrine tumor of the breast: A case report. Oncology Letters, 29, 79. https://doi.org/10.3892/ol.2024.14825
MLA
Ju, H., Liu, M."Primary neuroendocrine tumor of the breast: A case report". Oncology Letters 29.2 (2025): 79.
Chicago
Ju, H., Liu, M."Primary neuroendocrine tumor of the breast: A case report". Oncology Letters 29, no. 2 (2025): 79. https://doi.org/10.3892/ol.2024.14825
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