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Case Report Open Access

Myxoid leiomyosarcoma of the uterus in a woman of childbearing age: A case report

  • Authors:
    • Tingting Wang
    • Xiaoqin Wang
    • Jun Wu
    • Xin Li
    • Lina Peng
  • View Affiliations / Copyright

    Affiliations: Department of Gynecology, Women and Children's Hospital Affiliated to Ningbo University, Ningbo, Zhejiang 315000, P.R. China, Department of Gynecology, Women and Children's Hospital Affiliated to Ningbo University, Ningbo, Zhejiang 315000, P.R. China, Department of Imaging, Women and Children's Hospital Affiliated to Ningbo University, Ningbo, Zhejiang 315000, P.R. China
    Copyright: © Wang et al. This is an open access article distributed under the terms of Creative Commons Attribution License.
  • Article Number: 264
    |
    Published online on: April 2, 2025
       https://doi.org/10.3892/ol.2025.15010
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Abstract

Myxoid leiomyosarcoma of the uterus (MLMS) is an extremely rare malignancy characterized by a poor prognosis. The present report describes a rare case of MLMS in a woman of childbearing age. The patient was a 33‑year‑old woman who presented with lower abdominal pain and was initially diagnosed with uterine myoma by preoperative B‑mode ultrasound and magnetic resonance imaging. However, intraoperative pathological biopsy indicated the presence of a malignant tumor. The patient underwent total uterine and bilateral salpingectomy, along with pelvic lymph node biopsy, which confirmed the diagnosis of MLMS postoperatively. In a subsequent surgical procedure, the bilateral ovaries, omentum and appendix were also resected. The patient then received chemotherapy with gemcitabine and docetaxel and remains in good health, with no signs of recurrence. The present case report underscores the importance of early diagnosis and personalized treatment strategies for MLMS, particularly regarding their implications for fertility and survival outcomes in young women.
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1 

Mbatani N, Olawaiye AB and Prat J: Uterine sarcomas. Int J Gynaecol Obstet. 143 (Suppl):S51–S58. 2018. View Article : Google Scholar

2 

Chinese Anticancer Association Gynecological Tumor Professional Committee, . Diagnosis of uterine sarcoma in treatment guidelines (2021 edition). China Oncology. 31:513–519. 2021.(In Chinese).

3 

Harlow BL, Weiss NS and Lofton S: The epidemiology of sarcomas of the uterus. J Natl Cancer Inst. 76:399–402. 1986.PubMed/NCBI

4 

Istrate-Ofiţeru AM, Zorilă GL, Ruican D, Petrescu AM, Berbecaru EIA, Roşu GC, Căpitănescu RG, Nagy RD, Cercelaru L, Edu A, et al: Uterine myxoid leiomyosarcoma-A rare malignant tumor: The role of complex morphopathological assay. Review and case presentation. Rom J Morphol Embryol. 62:883–896. 2021. View Article : Google Scholar : PubMed/NCBI

5 

Sen A; FIGO, : FIGO 2009 classification for uterine sarcoma staging: FIGO 2023 endometrial cancer classification for carcinosarcoma staging. Int J Gynaecol Obstet. 167:12732024. View Article : Google Scholar : PubMed/NCBI

6 

Ng WK, Lui PCW and Ma L: Peritoneal washing cytology findings of disseminated myxoid leiomyosarcoma of uterus: Report of a case with emphasis on possible differential diagnosis. Diagn Cytopathol. 27:47–52. 2002. View Article : Google Scholar : PubMed/NCBI

7 

Takano Y, Morimura Y, Yamada H, Yanagida K, Sato A, Suzuki O and Suzuki T: Myxoid leiomyosarcoma of the uterus. Fukushima J Med Sci. 46:41–47. 2000. View Article : Google Scholar : PubMed/NCBI

8 

Gadducci A, Landoni F, Sartori E, Zola P, Maggino T, Lissoni A, Bazzurini L, Arisio R, Romagnolo C and Cristofani R: Uterine leiomyosarcoma: Analysis of treatment failures and survival. Gynecol Oncol. 62:25–32. 1996. View Article : Google Scholar : PubMed/NCBI

9 

Cui RR, Wright JD and Hou JY: Uterine leiomyosarcoma: A review of recent advances in molecular biology, clinical management and outcome. BJOG. 124:1028–1037. 2017. View Article : Google Scholar : PubMed/NCBI

10 

Antonio R, Dieg R and Daniele N: Diagnostic accuracy of ultrasound in the diagnosis of uterine leiomyomas and sarcomas. J Minim Invasive Gynecol. 31:28–36. 2024. View Article : Google Scholar : PubMed/NCBI

11 

Kagami S, Kashimura M, Toki N and Katuhata Y: Myxoid leiomyosarcoma of the uterus with subsequent pregnancy and delivery. Gynecol Oncol. 85:538–542. 2002. View Article : Google Scholar : PubMed/NCBI

12 

Mittal K, Popiolek D and Demopoulos RI: Uterine myxoid leiomyosarcoma within a leiomyoma. Hum Pathol. 31:398–400. 2000. View Article : Google Scholar : PubMed/NCBI

13 

Wankhade R, Sajjanar A, Dawande P and Noman O: A rare case of uterine myxoid leiomyosarcoma. Cureus. 15:e443032023.PubMed/NCBI

14 

Burch DM and Tavassoli FA: Myxoid leiomyosarcoma of the uterus. Histopathology. 59:1144–1155. 2011. View Article : Google Scholar : PubMed/NCBI

15 

Wang Y, Teng Y, Na S and Yuan Y: Pleomorphic leiomyosarcoma of the adrenal gland in a young woman: A case report and review of the literature. Onco Targets Ther. 13:4705–4713. 2020. View Article : Google Scholar : PubMed/NCBI

16 

Li RP, Zhang M, Gao J and Guo Y: Misdiagnosis and mistreatment of uterine myxoid leiomyosarcoma: A case report and literature review. Asian J Surg. 46:2714–2715. 2023. View Article : Google Scholar : PubMed/NCBI

17 

Giannini A, Cuccu I, D'Auge TG, De Angelis E, Laganà AS, Chiantera V, Caserta D, Vitale SG, Muzii L, D'Oria O, et al: The great debate: Surgical outcomes of laparoscopic versus laparotomic myomectomy. A meta-analysis to critically evaluate current evidence and look over the horizon. Eur J Obstet Gynecol Reprod Biol. 297:50–58. 2024. View Article : Google Scholar : PubMed/NCBI

18 

Berchuck A, Rubin SC, Hoskins WJ, Saigo PE, Pierce VK and Lewis JL: Treatment of uterine leiomyosarcoma. Obstet Gynecol. 71:845–850. 1988.PubMed/NCBI

19 

Giannini A, Golia D'Augè T, Bogani G, Laganà AS, Chiantera V, Vizza E, Muzii L and Di Donato V: Uterine sarcomas: A critical review of the literature. Eur J Obstet Gynecol Reprod Biol. 287:166–170. 2023. View Article : Google Scholar : PubMed/NCBI

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Copy and paste a formatted citation
Spandidos Publications style
Wang T, Wang X, Wu J, Li X and Peng L: Myxoid leiomyosarcoma of the uterus in a woman of childbearing age: A case report. Oncol Lett 29: 264, 2025.
APA
Wang, T., Wang, X., Wu, J., Li, X., & Peng, L. (2025). Myxoid leiomyosarcoma of the uterus in a woman of childbearing age: A case report. Oncology Letters, 29, 264. https://doi.org/10.3892/ol.2025.15010
MLA
Wang, T., Wang, X., Wu, J., Li, X., Peng, L."Myxoid leiomyosarcoma of the uterus in a woman of childbearing age: A case report". Oncology Letters 29.6 (2025): 264.
Chicago
Wang, T., Wang, X., Wu, J., Li, X., Peng, L."Myxoid leiomyosarcoma of the uterus in a woman of childbearing age: A case report". Oncology Letters 29, no. 6 (2025): 264. https://doi.org/10.3892/ol.2025.15010
Copy and paste a formatted citation
x
Spandidos Publications style
Wang T, Wang X, Wu J, Li X and Peng L: Myxoid leiomyosarcoma of the uterus in a woman of childbearing age: A case report. Oncol Lett 29: 264, 2025.
APA
Wang, T., Wang, X., Wu, J., Li, X., & Peng, L. (2025). Myxoid leiomyosarcoma of the uterus in a woman of childbearing age: A case report. Oncology Letters, 29, 264. https://doi.org/10.3892/ol.2025.15010
MLA
Wang, T., Wang, X., Wu, J., Li, X., Peng, L."Myxoid leiomyosarcoma of the uterus in a woman of childbearing age: A case report". Oncology Letters 29.6 (2025): 264.
Chicago
Wang, T., Wang, X., Wu, J., Li, X., Peng, L."Myxoid leiomyosarcoma of the uterus in a woman of childbearing age: A case report". Oncology Letters 29, no. 6 (2025): 264. https://doi.org/10.3892/ol.2025.15010
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