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Genomic and clinical‑pathological features of mucinous cystadenocarcinoma of the breast with HER2 amplification: A case report

  • Authors:
    • Liling Liu
    • Mingxian Li
    • Xinmin Qiu
    • Xirun Zheng
    • Guangjuan Zheng
    • Haifeng Yang
  • View Affiliations / Copyright

    Affiliations: Department of Pathology, The Second Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, Guangdong 510120, P.R. China
    Copyright: © Liu et al. This is an open access article distributed under the terms of Creative Commons Attribution License.
  • Article Number: 304
    |
    Published online on: April 16, 2025
       https://doi.org/10.3892/ol.2025.15050
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Abstract

Mucinous cystadenocarcinoma (MCA) of the breast is a rare, invasive carcinoma that resembles pancreatobiliary or ovarian MCA in terms of histological appearance. Most cases of MCA of the breast are negative for the estrogen receptor, progesterone receptor and ERBB2 (HER2). To the best of our knowledge, only five reports of HER2‑positive MCA cases have been reported in the English language, and no reports focusing on the molecular characteristics of HER2‑positive MCAs have been published. In the present study, a rare case of a 64‑year‑old woman with HER2‑positive MCA who underwent long‑term follow‑up without recurrence or distant metastasis is reported. In addition, a detailed analysis of the genomic characteristics of the tumor is provided.
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Copy and paste a formatted citation
Spandidos Publications style
Liu L, Li M, Qiu X, Zheng X, Zheng G and Yang H: Genomic and clinical‑pathological features of mucinous cystadenocarcinoma of the breast with HER2 amplification: A case report. Oncol Lett 29: 304, 2025.
APA
Liu, L., Li, M., Qiu, X., Zheng, X., Zheng, G., & Yang, H. (2025). Genomic and clinical‑pathological features of mucinous cystadenocarcinoma of the breast with HER2 amplification: A case report. Oncology Letters, 29, 304. https://doi.org/10.3892/ol.2025.15050
MLA
Liu, L., Li, M., Qiu, X., Zheng, X., Zheng, G., Yang, H."Genomic and clinical‑pathological features of mucinous cystadenocarcinoma of the breast with HER2 amplification: A case report". Oncology Letters 29.6 (2025): 304.
Chicago
Liu, L., Li, M., Qiu, X., Zheng, X., Zheng, G., Yang, H."Genomic and clinical‑pathological features of mucinous cystadenocarcinoma of the breast with HER2 amplification: A case report". Oncology Letters 29, no. 6 (2025): 304. https://doi.org/10.3892/ol.2025.15050
Copy and paste a formatted citation
x
Spandidos Publications style
Liu L, Li M, Qiu X, Zheng X, Zheng G and Yang H: Genomic and clinical‑pathological features of mucinous cystadenocarcinoma of the breast with HER2 amplification: A case report. Oncol Lett 29: 304, 2025.
APA
Liu, L., Li, M., Qiu, X., Zheng, X., Zheng, G., & Yang, H. (2025). Genomic and clinical‑pathological features of mucinous cystadenocarcinoma of the breast with HER2 amplification: A case report. Oncology Letters, 29, 304. https://doi.org/10.3892/ol.2025.15050
MLA
Liu, L., Li, M., Qiu, X., Zheng, X., Zheng, G., Yang, H."Genomic and clinical‑pathological features of mucinous cystadenocarcinoma of the breast with HER2 amplification: A case report". Oncology Letters 29.6 (2025): 304.
Chicago
Liu, L., Li, M., Qiu, X., Zheng, X., Zheng, G., Yang, H."Genomic and clinical‑pathological features of mucinous cystadenocarcinoma of the breast with HER2 amplification: A case report". Oncology Letters 29, no. 6 (2025): 304. https://doi.org/10.3892/ol.2025.15050
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