|
1
|
Prieto VG, Kazakov DV, Konstantinova AM,
McCluggage WG and Michal M: Extramammary Paget disease. WHO
Classification of Tumours, Skin Tumours. 5th edition. IARC; Lyon:
pp. 313–314. 2025
|
|
2
|
Wang YX, Cui XM, Zhang Q, Xu XQ, Sun Y,
Gao M and Gu LX: Pigmented extramammary Paget's disease of the
axilla: Two case reports and a literature review. Clin Cosmet
Investig Dermatol. 18:1909–1915. 2025. View Article : Google Scholar : PubMed/NCBI
|
|
3
|
Kiavash K, Kim S and Thompson AD:
‘Pigmented extramammary Paget disease’-a potential mimicker of
malignant melanoma and a pitfall in diagnosis: A case report and
review of the literature. Am J Dermatopathol. 41:45–49. 2019.
View Article : Google Scholar : PubMed/NCBI
|
|
4
|
Petersson F, Ivan D, Kazakov DV, Michal M
and Prieto VG: Pigmented Paget disease-a diagnostic pitfall
mimicking melanoma. Am J Dermatopathol. 31:223–226. 2009.
View Article : Google Scholar : PubMed/NCBI
|
|
5
|
Helwig EB and Graham JH: Anogenital
(extramammary) Paget's disease. A clinicopathological study.
Cancer. 16:387–403. 1963. View Article : Google Scholar : PubMed/NCBI
|
|
6
|
Konstantinova AM, Hayes MM, Stewart CJR,
Plaza JA, Michal M, Kerl K and Kazakov DV: Syringomatous structures
in extramammary Paget disease: A potential diagnostic pitfall. Am J
Dermatopathol. 38:653–657. 2016. View Article : Google Scholar : PubMed/NCBI
|
|
7
|
Roh SG, Park J, Park SK, Woo SH, Kim DW,
Kim HU and Yun SK: Extramammary Paget's disease associated with
underlying syringoma. Eur J Dermatol. 25:364–365. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
8
|
Konstantinova AM, Kacerovska D, Stewart
CJ, Szepe P, Pitha J, Sulc M, Bencik V, Michal M, Shideler B, Kerl
K and Kazakov DV: Syringocystadenocarcinoma papilliferum in
situ-like changes in extramammary Paget disease: A report of 11
cases. Am J Dermatopathol. 38:882–886. 2016. View Article : Google Scholar : PubMed/NCBI
|
|
9
|
Sheldon JD, Buckley K, Ulman C and Chung
CG: Anogenital syringocystadenocarcinoma papilliferum in situ or
anaplastic extramammary Paget disease? A unifying concept and
review of the literature. J Cutan Pathol. 48:1075–1079. 2021.
View Article : Google Scholar : PubMed/NCBI
|
|
10
|
Sangüeza OP, Calonje JE, Requena L and
Singh R: Syringoma. WHO Classification of Tumours, Skin Tumours.
5th edition. IARC; Lyon: pp. 219–220. 2025
|
|
11
|
Kazakov DV, Calonje JE and Requena L:
Syringocystadeno-carcinoma papilliferum. WHO Classification of
Tumours, Skin Tumours. 5th edition. IARC; Lyon: pp. 268–269.
2025
|
|
12
|
Detweiler CJ, Turrentine JE, Shedd AD,
Ioffe B and Detweiler JG: Acantholytic anaplastic extramammary
Paget disease. Cutis. 104:E26–E29. 2019.PubMed/NCBI
|
|
13
|
Oh YJ, Lew BL and Sim WY: Acantholytic
anaplastic extramammary Paget's disease: A case report and review
of the literature. Ann Dermatol. 23 (Suppl 2):S226–S230. 2011.
View Article : Google Scholar : PubMed/NCBI
|
|
14
|
Namiki T, Iikawa M, Otsuki Y, Ueno M and
Yokozeki H: Ectopic extramammary Paget disease mimicking Bowen
disease. J Am Acad Dermatol. 75:e9–e10. 2016. View Article : Google Scholar : PubMed/NCBI
|
|
15
|
Du X, Yin X, Zhou N, Zhang G, Shi H and
Cao S: Extramammary Paget's disease mimicking acantholytic squamous
cell carcinoma in situ: A case report. J Cutan Pathol. 37:683–686.
2010. View Article : Google Scholar : PubMed/NCBI
|
|
16
|
Iga N, Fujii H, Miyake T, Ehara M and
Kore-Eda S: Syringocystadenocarcinoma papilliferum in the perianal
area. Case Rep Dermatol. 7:84–89. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
17
|
Plant MA, Sade S, Hong C and Ghazarian DM:
Syringocystadeno-carcinoma papilliferum in situ of the penis. Eur J
Dermatol. 22:405–406. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
18
|
Langner C and Ott A:
Syringocystadenocarcinoma papilliferum in situ originating from the
perianal skin. APMIS. 117:148–150. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
19
|
Ishida-Yamamoto A, Sato K, Wada T,
Takahashi H and Iizuka H: Syringocystadenocarcinoma papilliferum:
Case report and immunohistochemical comparison with its benign
counterpart. J Am Acad Dermatol. 45:755–759. 2001. View Article : Google Scholar : PubMed/NCBI
|
|
20
|
Chen X, Zhou Y, Zhang Z, Yuan G, He S and
Xiao F: Identification of mitochondrial dysfunction-related
biomarkers and immune infiltration in liver ischemia-reperfusion
injury via integrated bioinformatics and machine learning. Biochem
Biophys Res Commun. 807:1534352026. View Article : Google Scholar : PubMed/NCBI
|
|
21
|
Kitamura S, Yanagi T, Imafuku K, Hata H
and Shimizu H: Lipofuscin deposition causes the pigmentation of
apocrine hidrocystoma. J Dermatol. 45:91–94. 2018. View Article : Google Scholar : PubMed/NCBI
|
![Histopathological features of PEMPD.
(A) Proliferation of carcinoma cells containing rich cytoplasm and
large, round to oval nuclei showing nest formation within the
epidermis. Within the nests of carcinoma cells, focal glandular
formation was observed (arrows; haematoxylin and eosin staining;
magnification, ×200). (B) Involvement of carcinoma cells into the
hair follicles and sebaceous ducts (arrows; haematoxylin and eosin
staining; magnification, ×200). (C) Involvement of carcinoma cells
into the eccrine ducts (arrows; haematoxylin and eosin staining;
magnification, ×100). (D) Presence of melanin pigment within the
cytoplasm of carcinoma cells in the in situ lesion
(haematoxylin and eosin staining; magnification, ×400). (E)
Invasive carcinoma cells also contained melanin pigment in their
cytoplasm (haematoxylin and eosin staining; magnification, ×400).
(F) Syringomatous structures in PEMPD. Small ductal or tadpole-like
structures comprised of attenuated bland epithelial cells within
the sclerotic stroma were observed in the upper dermis. A
syringomatous structure was present under the in situ lesion
of extramammary Paget disease. (haematoxylin and eosin staining;
magnification, ×100). (G) Syringocystadenocarcinoma papilliferum
in situ-like change in PEMPD. Epidermal hyperplasia with
papillary proliferation containing carcinoma cells was noted. Dense
plasma cell infiltration in the papillary dermis was observed
(inset) [haematoxylin and eosin staining; magnification, ×100 or
×400 (inset)]. PEMPD, primary extramammary Paget disease.](/article_images/ol/32/1/ol-32-01-15662-g00.jpg)
