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Article

Logistic regression analysis of risk factors for abdominal adhesion during hyperthermic intraperitoneal chemotherapy for ovarian cancer

  • Authors:
    • Jinfen Yao
    • Jie Chen
  • View Affiliations / Copyright

    Affiliations: Department of Radiation Center, Shanghai First Maternity and Infant Hospital, School of Medicine, Tongji University, Shanghai 200092, P.R. China
  • Article Number: 393
    |
    Published online on: July 3, 2026
       https://doi.org/10.3892/ol.2026.15748
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Abstract

The present study aimed to explore the risk factors for abdominal adhesion during hyperthermic intraperitoneal chemotherapy (HIPEC) for ovarian cancer via logistic regression analysis. The present study is a retrospective analysis involving 165 patients with ovarian cancer treated at The Department of Gynecology, Shanghai First Maternity and Infant Hospital (Shanghai, China) from February 2021 to June 2023. All patients were treated with HIPEC or adjuvant therapy. During the treatment, the patients were divided into the control (n=61) and observation (n=104) groups according to the presence of abdominal adhesion. The results of the present study highlighted the notable role of monitoring biomarkers such as C‑reactive protein and plasminogen activator inhibitor‑1 in predicting the risk of abdominal adhesions in patients with ovarian cancer treated with HIPEC. By optimizing surgical techniques, controlling inflammatory reactions, adopting anti‑adhesion strategies and implementing detailed preoperative assessment and preventive measures for patients undergoing HIPEC, the incidence of adhesions may be effectively reduced and treatment safety improved.
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Copy and paste a formatted citation
Spandidos Publications style
Yao J and Chen J: Logistic regression analysis of risk factors for abdominal adhesion during hyperthermic intraperitoneal chemotherapy for ovarian cancer. Oncol Lett 32: 393, 2026.
APA
Yao, J., & Chen, J. (2026). Logistic regression analysis of risk factors for abdominal adhesion during hyperthermic intraperitoneal chemotherapy for ovarian cancer. Oncology Letters, 32, 393. https://doi.org/10.3892/ol.2026.15748
MLA
Yao, J., Chen, J."Logistic regression analysis of risk factors for abdominal adhesion during hyperthermic intraperitoneal chemotherapy for ovarian cancer". Oncology Letters 32.3 (2026): 393.
Chicago
Yao, J., Chen, J."Logistic regression analysis of risk factors for abdominal adhesion during hyperthermic intraperitoneal chemotherapy for ovarian cancer". Oncology Letters 32, no. 3 (2026): 393. https://doi.org/10.3892/ol.2026.15748
Copy and paste a formatted citation
x
Spandidos Publications style
Yao J and Chen J: Logistic regression analysis of risk factors for abdominal adhesion during hyperthermic intraperitoneal chemotherapy for ovarian cancer. Oncol Lett 32: 393, 2026.
APA
Yao, J., & Chen, J. (2026). Logistic regression analysis of risk factors for abdominal adhesion during hyperthermic intraperitoneal chemotherapy for ovarian cancer. Oncology Letters, 32, 393. https://doi.org/10.3892/ol.2026.15748
MLA
Yao, J., Chen, J."Logistic regression analysis of risk factors for abdominal adhesion during hyperthermic intraperitoneal chemotherapy for ovarian cancer". Oncology Letters 32.3 (2026): 393.
Chicago
Yao, J., Chen, J."Logistic regression analysis of risk factors for abdominal adhesion during hyperthermic intraperitoneal chemotherapy for ovarian cancer". Oncology Letters 32, no. 3 (2026): 393. https://doi.org/10.3892/ol.2026.15748
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