BCR translocation to derivative chromosome 2: A new case of chronic myeloid leukemia with a complex variant translocation and Philadelphia chromosome

Gale RP and Canaani E: An 8-kilobase abl RNA transcript in chronic myelogenous leukemia. Proc Natl Acad Sci USA. 81:5648–5652. 1984. View Article : Google Scholar : PubMed/NCBI

De Klein A, van Kessel AG, Grosveld G, Bartram CR, Hagemeijer A, Bootsma D, Spurr NK, Heisterkamp A, Groffen J and Stephenson JR: A cellular oncogene is translocated to the Philadelphia chromosome in chronic myelogenous leukaemia. Nature. 300:765–777. 1982.PubMed/NCBI

Rowley JD: A new consistent chromosomal abnormality in chronic myelogenous leukemia identified by quinacrine fluorescence and Giemsa staining. Nature. 243:290–291. 1973. View Article : Google Scholar : PubMed/NCBI

Lugo T, Pendergast A, Müller A and Witte O: Tyrosine kinase activity and transformation potency of bcr-abl oncogene products. Science. 247:1079–1082. 1990. View Article : Google Scholar : PubMed/NCBI

Johansson B, Fioretos T and Mitelman F: Cytogenetic and molecular genetic evolution of chronic myeloid leukemia. Acta Haematol. 107:76–94. 2002. View Article : Google Scholar : PubMed/NCBI

Huret JL: Complex translocations, simple variant translocations and Ph-negative cases in chronic myelogenous leukaemia. Hum Genet. 85:565–568. 1990. View Article : Google Scholar : PubMed/NCBI

Hagemeijer A, de Klein A, Godde-Salz E, Turc-Carel C, Smit EME, van Aghtoven AJ and Grosveld GC: Translocation of c-abl to ‘masked’ Ph in chronic myeloid leukemia. Cancer Genet Cytogenet. 18:95–104. 1985.

Reid A, Gribble SM, Huntly BJ, Andrews KM, Campbell L, Grace CD, Wood ME, Green AR and Nacheva EP: Variant Philadelphia translocations in chronic myeloid leukaemia can mimic typical blast crisis chromosome abnormalities or classic t(9;22): a report of two cases. Br J Haematol. 113:439–442. 2001. View Article : Google Scholar

Claussen U, Michel S, Mühlig P, Westermann M, Grummt UW, Kromeyer-Hauschild K and Liehr T: Demystifying chromosome preparation and the implications for the concept of chromosome condensation during mitosis. Cytogenet Genome Res. 98:136–146. 2002. View Article : Google Scholar : PubMed/NCBI

Mitelman F: ISCN An International System for Human Cytogenetic Nomenclature. Karger; Basel: 1995

Al-Achkar W, Wafa A and Nweder MS: A complex translocation t(5;9;22) in Philadelphia cells involving the short arm of chromosome 5 in a case of chronic myelogenous leukemia. J Exp Clin Cancer Res. 26:411–415. 2007.PubMed/NCBI

Mitelman F, Johansson B and Mertens F: http://cgap.nci.nih.gov/chromosomes/Mitelman. Mitelman database on chromosome abberrations in cancer. Accessed Oct. 25, 2007

La Starza R, Testoni N, Lafage-Pochitaloff M, Ruggeri D, Ottaviani E, Perla G, Martelli MF, Marynen P and Mecucci C: Complex variant Philadelphia translocations involving the short arm of chromosome 6 in chronic myeloid leukemia. Haematologica. 87:143–147. 2002.

Fitzgerald PH and Morris CM: Complex chromosomal translocations in the Philadelphia chromosome leukemias. Serial translocations or a concerted genomic rearrangement? Cancer Genet Cytogenet. 57:143–151. 1991. View Article : Google Scholar

Nacheva E, Holloway T, Brown K, Bloxham D and Green AR: Philadelphia-negative chronic myeloid leukaemia: detection by FISH of BCR-ABL fusion gene localized either to chromosome 9 or chromosome 22. Br J Haematol. 87:409–412. 1994. View Article : Google Scholar

Reid AG, Huntly BJP, Grace C, Green AR and Nacheva EP: Survival implications of molecular heterogeneity in variant Philadelphia-positive chronic myeloid leukaemia. Br J Haematol. 121:419–427. 2003. View Article : Google Scholar : PubMed/NCBI