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Print ISSN: 1792-1074 Online ISSN: 1792-1082
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Article

Surgical treatments for squamous cell carcinoma of the esophagus reaching to the muscularis mucosa or the upper third of the submucosal layer hemodialysis

  • Authors:
    • Junya Oguma
    • Soji Ozawa
    • Yoshiro Saikawa
    • Yuko Kitagawa
  • View Affiliations / Copyright

    Affiliations: Department of Surgery, School of Medicine, Keio University, Tokyo 160-8582, Japan
  • Pages: 521-525
    |
    Published online on: May 1, 2010
       https://doi.org/10.3892/ol_00000092
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Abstract

We studied the surgical treatments of patients with either esophageal cancer reaching to the muscularis mucosae (m3) or with a slight invasion of the submucosa (sm1). We reviewed the records and examined the clinicopathological features of 29 patients with m3 or sm1 esophageal squamous cell carcinoma who had undergone surgery. Lymph node metastasis was noted in 6.3% (1 patient) of patients with m3 cancers and in 38.5% (5 patients) of those with sm1 cancers. The incidence of lymph node metastasis was higher in the sm1 than in the m3 group, but the difference was not significant. Lymphatic invasion (ly) was noted in 12.3% (2 patients) of patients with m3 cancers and in 53.8% (7 patients) of those with sm1 cancers. The incidence of ly was significantly higher in the sm1 group than in the m3 group (P<0.05). In a multivariate analysis of factors for predicting lymph node metastasis, the presence of ly was the only significant predictor (P<0.05). The preoperative diagnostic accuracies of endoscopic ultrasonography (EUS), esophagogastroduodenoscopy (EGD) and an upper gastrointestinal series (UGS) for predicting depth of invasion were 27.8, 31.0 and 41.4%, respectively, with the majority of the misdiagnoses being overestimations. In conclusion, we suggested that ly is associated with lymph node metastasis in m3 or sm1 esophageal cancer. This association is significant for treatment-related decision making.
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Copy and paste a formatted citation
Spandidos Publications style
Oguma J, Ozawa S, Saikawa Y and Kitagawa Y: Surgical treatments for squamous cell carcinoma of the esophagus reaching to the muscularis mucosa or the upper third of the submucosal layer hemodialysis . Oncol Lett 1: 521-525, 2010.
APA
Oguma, J., Ozawa, S., Saikawa, Y., & Kitagawa, Y. (2010). Surgical treatments for squamous cell carcinoma of the esophagus reaching to the muscularis mucosa or the upper third of the submucosal layer hemodialysis . Oncology Letters, 1, 521-525. https://doi.org/10.3892/ol_00000092
MLA
Oguma, J., Ozawa, S., Saikawa, Y., Kitagawa, Y."Surgical treatments for squamous cell carcinoma of the esophagus reaching to the muscularis mucosa or the upper third of the submucosal layer hemodialysis ". Oncology Letters 1.3 (2010): 521-525.
Chicago
Oguma, J., Ozawa, S., Saikawa, Y., Kitagawa, Y."Surgical treatments for squamous cell carcinoma of the esophagus reaching to the muscularis mucosa or the upper third of the submucosal layer hemodialysis ". Oncology Letters 1, no. 3 (2010): 521-525. https://doi.org/10.3892/ol_00000092
Copy and paste a formatted citation
x
Spandidos Publications style
Oguma J, Ozawa S, Saikawa Y and Kitagawa Y: Surgical treatments for squamous cell carcinoma of the esophagus reaching to the muscularis mucosa or the upper third of the submucosal layer hemodialysis . Oncol Lett 1: 521-525, 2010.
APA
Oguma, J., Ozawa, S., Saikawa, Y., & Kitagawa, Y. (2010). Surgical treatments for squamous cell carcinoma of the esophagus reaching to the muscularis mucosa or the upper third of the submucosal layer hemodialysis . Oncology Letters, 1, 521-525. https://doi.org/10.3892/ol_00000092
MLA
Oguma, J., Ozawa, S., Saikawa, Y., Kitagawa, Y."Surgical treatments for squamous cell carcinoma of the esophagus reaching to the muscularis mucosa or the upper third of the submucosal layer hemodialysis ". Oncology Letters 1.3 (2010): 521-525.
Chicago
Oguma, J., Ozawa, S., Saikawa, Y., Kitagawa, Y."Surgical treatments for squamous cell carcinoma of the esophagus reaching to the muscularis mucosa or the upper third of the submucosal layer hemodialysis ". Oncology Letters 1, no. 3 (2010): 521-525. https://doi.org/10.3892/ol_00000092
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