Serous microcystic adenoma of the pancreatic head: Report of two cases and review of the literature

Pu,Jiarui; Tong,Qiangsong; Zhou,Chengkai; Yang,Xiuping; Zheng,Liduan

doi:10.3892/ol_00000126

July-August 2010 Volume 1 Issue 4

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July-August 2010 Volume 1 Issue 4

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Article

Serous microcystic adenoma of the pancreatic head: Report of two cases and review of the literature

Authors:
- Jiarui Pu
- Qiangsong Tong
- Chengkai Zhou
- Xiuping Yang
- Liduan Zheng
View Affiliations / Copyright

Affiliations: Department of Surgery, Union Hospital of Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022 Hubei, P.R. China
Pages: 723-727
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Published online on: July 1, 2010

https://doi.org/10.3892/ol_00000126
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Abstract

Serous microcystic adenomas (SMAs), also known as glycogen-rich cystadenomas, are uncommon exocrine tumors mainly involved in the body and tail of the pancreas. In this study, we report two SMA cases of the pancreatic head. In case 1, a 47-year-old woman was referred to our hospital for abdominal bloating and back pain; in case 2, a pancreatic space-occupying lesion was incidentally discovered in an asymptomatic 71-year-old female during an ultrasound. In both cases, a computer tomography scan showed well-demarcated and multilocular cysts in the head of the pancreas, and a central scar and calcifications were noted in case 1. During the exploratory laparotomies, the multiple cystic masses were found in the pancreatic head. A segmental resection of the pancreas and pancreatic jejunal anastomosis were performed. Histologically, the tumors were composed of tiny cysts that were filled with clear fluid and lined by a single layer of cuboidal cells with round, centrally located nuclei and clear cytoplasm, without cellular atypia. Immunohistochemical studies showed that the neoplastic cells were positive for cytokeratin 7 and vimentin but negative for synaptophysin and cytokeratin 20. A postoperative follow-up indicated no recurrence in the patients. We reviewed the literature regarding the etiology, clinical presentation, imaging characteristics, features and management of this lesion.

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Journals

International Journal of Molecular Medicine

International Journal of Oncology

Molecular Medicine Reports

Oncology Reports

Experimental and Therapeutic Medicine

Oncology Letters

Biomedical Reports

Molecular and Clinical Oncology

World Academy of Sciences Journal

International Journal of Functional Nutrition

International Journal of Epigenetics

Medicine International

Serous microcystic adenoma of the pancreatic head: Report of two cases and review of the literature

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