Pseudoangiomatous stromal hyperplasia: An observation on its microscopic involvement in breast carcinoma and the presence of lymph node metastases

Coyne,John D.

doi:10.3892/ol_00000141

September-October 2010 Volume 1 Issue 5

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September-October 2010 Volume 1 Issue 5

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Article

Pseudoangiomatous stromal hyperplasia: An observation on its microscopic involvement in breast carcinoma and the presence of lymph node metastases

Authors:
- John D. Coyne
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Affiliations: Department of Pathology, Royal Liverpool Hospital, Duncan Building, Liverpool L7 8XP, UK. johnnycoyne@doctors.org.uk
Pages: 805-807
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Published online on: September 1, 2010

https://doi.org/10.3892/ol_00000141
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Abstract

The spaces of pseudoangiomatous stromal hyperplasia (PASH) are postulated to be important in the intramammary spread of breast carcinoma. The present study aimed to note the prevalence of inconspicuous, microscopic foci of PASH (identified as CD34+ve, CD31-ve and D2-40-ve spaces containing tumour emboli) involved in breast carcinoma and to establish the significance of its relationship to lymph node metastases. A total of 80 cases of breast carcinoma were examined for microscopic foci of PASH permeated by carcinoma and, of the four cases found to demonstrate such involvement, three had lymph node metastases.

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Journals

International Journal of Molecular Medicine

International Journal of Oncology

Molecular Medicine Reports

Oncology Reports

Experimental and Therapeutic Medicine

Oncology Letters

Biomedical Reports

Molecular and Clinical Oncology

World Academy of Sciences Journal

International Journal of Functional Nutrition

International Journal of Epigenetics

Medicine International

Pseudoangiomatous stromal hyperplasia: An observation on its microscopic involvement in breast carcinoma and the presence of lymph node metastases

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Abstract

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