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Oncology Letters
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Print ISSN: 1792-1074 Online ISSN: 1792-1082
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September-October 2010 Volume 1 Issue 5

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International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

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Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

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Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

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Case Report

Synovial sarcoma individual chemotherapy directed by collagen gel droplet embedded culture drug sensitivity test: A case report

  • Authors:
    • Feng Gu
    • Yongjie Ma
    • Yu Fan
    • Ronggang Lang
    • Ting Ding
    • Xishan Hao
    • Yun Gong
    • Hisayuki Kobayashi
    • Zhiwei Fang
    • Li Fu
  • View Affiliations / Copyright

    Affiliations: Anti-tumor Drug Sensitivity Test Lab, Department of Breast Cancer Pathology and Research Laboratory, Key Laboratory of Breast Cancer Prevention and Therapy of the Ministry of Education, Key Laboratory of Cancer Prevention and Therapy of Tianjin, Tianjin 300060, P.R. China
  • Pages: 885-888
    |
    Published online on: September 1, 2010
       https://doi.org/10.3892/ol_00000157
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Abstract

The collagen gel droplet embedded culture-drug sensitivity test (CD-DST) is an anticancer drug sensitivity test developed about 10 years ago. This study reports the application of this test in the choice of neoadjuvant chemotherapy for the treatment of one patient with a large synovial sarcoma in the right shank. A 28-year old man presented at our hospital with a large mass in his right shank which had a hard texture and an obscure boundary. The histopathological diagnosis of excisional biopsy specimens was synovial sarcoma with low differentiation. Theprubicin/Cisplatin (THP/CDDP) neoadjuvant chemotherapy was selected based on the results obtained from the CD-DST. After three courses, a computed tomography (CT) scan was performed which indicated that the volume of the tumor had decreased significantly. Additionally, tumor necrosis, as well as the clinical response, showed complete response. The histopathological diagnosis of wide excision specimens indicated a grade III chemotherapy response. The patient was alive and without recurrence after a follow-up of 16 months. Our results indicated that the CD-DST is a useful tool for selecting neoadjuvant chemotherapeutic drugs for patients with synovial sarcoma.
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Copy and paste a formatted citation
Spandidos Publications style
Gu F, Ma Y, Fan Y, Lang R, Ding T, Hao X, Gong Y, Kobayashi H, Fang Z, Fu L, Fu L, et al: Synovial sarcoma individual chemotherapy directed by collagen gel droplet embedded culture drug sensitivity test: A case report . Oncol Lett 1: 885-888, 2010.
APA
Gu, F., Ma, Y., Fan, Y., Lang, R., Ding, T., Hao, X. ... Fu, L. (2010). Synovial sarcoma individual chemotherapy directed by collagen gel droplet embedded culture drug sensitivity test: A case report . Oncology Letters, 1, 885-888. https://doi.org/10.3892/ol_00000157
MLA
Gu, F., Ma, Y., Fan, Y., Lang, R., Ding, T., Hao, X., Gong, Y., Kobayashi, H., Fang, Z., Fu, L."Synovial sarcoma individual chemotherapy directed by collagen gel droplet embedded culture drug sensitivity test: A case report ". Oncology Letters 1.5 (2010): 885-888.
Chicago
Gu, F., Ma, Y., Fan, Y., Lang, R., Ding, T., Hao, X., Gong, Y., Kobayashi, H., Fang, Z., Fu, L."Synovial sarcoma individual chemotherapy directed by collagen gel droplet embedded culture drug sensitivity test: A case report ". Oncology Letters 1, no. 5 (2010): 885-888. https://doi.org/10.3892/ol_00000157
Copy and paste a formatted citation
x
Spandidos Publications style
Gu F, Ma Y, Fan Y, Lang R, Ding T, Hao X, Gong Y, Kobayashi H, Fang Z, Fu L, Fu L, et al: Synovial sarcoma individual chemotherapy directed by collagen gel droplet embedded culture drug sensitivity test: A case report . Oncol Lett 1: 885-888, 2010.
APA
Gu, F., Ma, Y., Fan, Y., Lang, R., Ding, T., Hao, X. ... Fu, L. (2010). Synovial sarcoma individual chemotherapy directed by collagen gel droplet embedded culture drug sensitivity test: A case report . Oncology Letters, 1, 885-888. https://doi.org/10.3892/ol_00000157
MLA
Gu, F., Ma, Y., Fan, Y., Lang, R., Ding, T., Hao, X., Gong, Y., Kobayashi, H., Fang, Z., Fu, L."Synovial sarcoma individual chemotherapy directed by collagen gel droplet embedded culture drug sensitivity test: A case report ". Oncology Letters 1.5 (2010): 885-888.
Chicago
Gu, F., Ma, Y., Fan, Y., Lang, R., Ding, T., Hao, X., Gong, Y., Kobayashi, H., Fang, Z., Fu, L."Synovial sarcoma individual chemotherapy directed by collagen gel droplet embedded culture drug sensitivity test: A case report ". Oncology Letters 1, no. 5 (2010): 885-888. https://doi.org/10.3892/ol_00000157
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