IMMUNOHISTOCHEMISTRY OF ECCRINE POROCARCINOMA

  • Authors:
    • U WOLLINA
    • E CASTELLI
  • View Affiliations

  • Published online on: January 1, 1994     https://doi.org/10.3892/or.1.1.101
  • Pages: 101-105
Metrics: Total Views: 0 (Spandidos Publications: | PMC Statistics: )
Total PDF Downloads: 0 (Spandidos Publications: | PMC Statistics: )


Abstract

The eccrine porocarcinoma is a rare adnexal tumor of human skin. It has been related to the acrosyringeum of the sweat gland. An immunohistochemical study on paraffin sections of eight porocarcinomas and a control group of 29 poromas was conducted to investigate the differentiation of porocarcinomas. Antibodies against (neuro-) glandular antigens and selected intermediate filaments were used for indirect immunoperoxidase staining with amino ethyl carbazole. Porocarcinomas disclosed variable amounts of cells labeled with CEA, S100A, LS59, NKI/C-3, Cam 5.2, Vim9(1), and wide spectrum keratin. Cellular phenotypes showed greater variability than the benign poromas. The immunostaining patterns of porocarcinomas suggest a differentiation program towards inner duct cells and myoepithelium thereby questioning their classification as acrosyringeal neoplasms.

Related Articles

Journal Cover

January 1994
Volume 1 Issue 1

Print ISSN: 1021-335X
Online ISSN:1791-2431

Sign up for eToc alerts

Recommend to Library

Copy and paste a formatted citation
x
Spandidos Publications style
WOLLINA U and WOLLINA U: IMMUNOHISTOCHEMISTRY OF ECCRINE POROCARCINOMA. Oncol Rep 1: 101-105, 1994
APA
WOLLINA, U., & WOLLINA, U. (1994). IMMUNOHISTOCHEMISTRY OF ECCRINE POROCARCINOMA. Oncology Reports, 1, 101-105. https://doi.org/10.3892/or.1.1.101
MLA
WOLLINA, U., CASTELLI, E."IMMUNOHISTOCHEMISTRY OF ECCRINE POROCARCINOMA". Oncology Reports 1.1 (1994): 101-105.
Chicago
WOLLINA, U., CASTELLI, E."IMMUNOHISTOCHEMISTRY OF ECCRINE POROCARCINOMA". Oncology Reports 1, no. 1 (1994): 101-105. https://doi.org/10.3892/or.1.1.101