HORMONES IN MALE-PATIENTS WITH ADVANCED ESOPHAGEAL-CARCINOMA

  • Authors:
    • JM BHATAVDEKAR
    • DD PATEL
    • CR TRIVEDI
    • RS DAVE
    • SP NADKARNI
    • NH KARELIA
    • HH VORA
    • M GHOSH
    • SB PATEL
    • TP SUTHAR
    • SS DOCTOR
    • DB BALAR
  • View Affiliations

  • Published online on: January 1, 1994     https://doi.org/10.3892/or.1.1.255
  • Pages: 255-257
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Abstract

Hormones are believed to play a dominant role as promoters in the growth and development of hormone-dependent cancers. Much less is known about the circulating hormones in male patients with oesophageal cancer. This lack of attention led us to evaluate the role of peptide and steroid hormones (by RIA) in male patients with oesophageal cancer (n=49). Blood samples of patients were collected pretherapeutically and data was compared with age matched controls (n=25). In this retrospective study, significantly high levels of FSH (P<0.02), LH (P<0.001) and prolactin (P<0.001) were observed with concomitant low levels of estradiol (P<0.001), DHEA-S (P<0.02) and testosterone (P<0.001) in patients when compared with respective controls. The patients when grouped according to anatomical site and histological type of the tumor, intergroup variation was not observed in these hormones. From our, study, it seems that hormonal imbalance or altered ratio of peptide and steroid hormones might be playing a significant role in the development and/or progression of oesophageal carcinoma in men.

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January 1994
Volume 1 Issue 1

Print ISSN: 1021-335X
Online ISSN:1791-2431

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Spandidos Publications style
BHATAVDEKAR J, PATEL D, TRIVEDI C, DAVE R, NADKARNI S, KARELIA N, VORA H, GHOSH M, PATEL S, SUTHAR T, SUTHAR T, et al: HORMONES IN MALE-PATIENTS WITH ADVANCED ESOPHAGEAL-CARCINOMA. Oncol Rep 1: 255-257, 1994
APA
BHATAVDEKAR, J., PATEL, D., TRIVEDI, C., DAVE, R., NADKARNI, S., KARELIA, N. ... BALAR, D. (1994). HORMONES IN MALE-PATIENTS WITH ADVANCED ESOPHAGEAL-CARCINOMA. Oncology Reports, 1, 255-257. https://doi.org/10.3892/or.1.1.255
MLA
BHATAVDEKAR, J., PATEL, D., TRIVEDI, C., DAVE, R., NADKARNI, S., KARELIA, N., VORA, H., GHOSH, M., PATEL, S., SUTHAR, T., DOCTOR, S., BALAR, D."HORMONES IN MALE-PATIENTS WITH ADVANCED ESOPHAGEAL-CARCINOMA". Oncology Reports 1.1 (1994): 255-257.
Chicago
BHATAVDEKAR, J., PATEL, D., TRIVEDI, C., DAVE, R., NADKARNI, S., KARELIA, N., VORA, H., GHOSH, M., PATEL, S., SUTHAR, T., DOCTOR, S., BALAR, D."HORMONES IN MALE-PATIENTS WITH ADVANCED ESOPHAGEAL-CARCINOMA". Oncology Reports 1, no. 1 (1994): 255-257. https://doi.org/10.3892/or.1.1.255