NONE OF THE KNOWN DIFFERENT FIBROBLAST GROWTH-FACTOR RECEPTOR-2 CARBOXY-TERMINAL TAILS ARE RESTRICTED TO CANCER-CELLS

  • Authors:
    • E GILBERT
    • D MULLER
    • R BREATHNACH
  • View Affiliations

  • Published online on: May 1, 1994     https://doi.org/10.3892/or.1.3.639
  • Pages: 639-643
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Abstract

Fibroblast growth factor receptor-2 cDNAs derived from healthy tissues code for proteins with a 63 amino acid carboxy-terminal tail. Some cDNAs isolated from human tumour cDNA libraries code for receptors with 11, 15 or 29 amino acid carboxy-terminal tails. However, the important issue as to whether these latter tails are tumour specific markers has remained unresolved. We show that mRNAs coding for FGFR-2 proteins with carboxy-terminal tails of 11, 29 and 63 amino acids are co-expressed not only in many tumour tissues but also in normal human tissues, while the 15 amino acid tail appears to reflect a cloning artefact.

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May 1994
Volume 1 Issue 3

Print ISSN: 1021-335X
Online ISSN:1791-2431

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Spandidos Publications style
GILBERT E, MULLER D and BREATHNACH R: NONE OF THE KNOWN DIFFERENT FIBROBLAST GROWTH-FACTOR RECEPTOR-2 CARBOXY-TERMINAL TAILS ARE RESTRICTED TO CANCER-CELLS. Oncol Rep 1: 639-643, 1994
APA
GILBERT, E., MULLER, D., & BREATHNACH, R. (1994). NONE OF THE KNOWN DIFFERENT FIBROBLAST GROWTH-FACTOR RECEPTOR-2 CARBOXY-TERMINAL TAILS ARE RESTRICTED TO CANCER-CELLS. Oncology Reports, 1, 639-643. https://doi.org/10.3892/or.1.3.639
MLA
GILBERT, E., MULLER, D., BREATHNACH, R."NONE OF THE KNOWN DIFFERENT FIBROBLAST GROWTH-FACTOR RECEPTOR-2 CARBOXY-TERMINAL TAILS ARE RESTRICTED TO CANCER-CELLS". Oncology Reports 1.3 (1994): 639-643.
Chicago
GILBERT, E., MULLER, D., BREATHNACH, R."NONE OF THE KNOWN DIFFERENT FIBROBLAST GROWTH-FACTOR RECEPTOR-2 CARBOXY-TERMINAL TAILS ARE RESTRICTED TO CANCER-CELLS". Oncology Reports 1, no. 3 (1994): 639-643. https://doi.org/10.3892/or.1.3.639