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Oncology Reports
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Print ISSN: 1021-335X Online ISSN: 1791-2431
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July 1994 Volume 1 Issue 4

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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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July 1994 Volume 1 Issue 4

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Article

MOLECULAR-CLONING OF THE HUMAN CYCG1 GENE ENCODING A G-TYPE CYCLIN - OVEREXPRESSION IN HUMAN OSTEOSARCOMA CELLS

  • Authors:
    • LT WU
    • L LIU
    • A YEE
    • D CARBONARO-HALL
    • VT TOLO
    • FL HALL

  • View Affiliations / Copyright

    Affiliations: CHILDRENS HOSP LOS ANGELES,RES INST,DIV ORTHOPAED SURG,LOS ANGELES,CA 90027. UNIV SO CALIF,SCH PHARM,DEPT MOLEC PHARMACOL & TOXICOL,LOS ANGELES,CA 90033.
  • Pages: 705-711
    |
    Published online on: July 1, 1994
       https://doi.org/10.3892/or.1.4.705
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Abstract

Cyclins constitute a growing family of regulatory proteins that complex with, and activate, protein kinases involved in cell cycle control. Dysregulation of cyclin expression and/or cyclin-dependent kinase (cdk) activities may play a pivotal role in oncogenesis. In this report, we characterize a novel human cyclin gene by molecular cloning. This gene, designated CYCG1, encodes a human homologue of the rat G-type cyclin, exhibiting structural features and conserved sequence motifs of identified G(1) cyclins. The CYCG1 gene is expressed constitutively in synchronized human WI-38 fibroblasts and MG-63 osteosarcoma cells, which is reminiscent of CLN3 in Saccharomyces cerevisiae. Marked overexpression of CYCG1 is observed in a subset of human osteosarcoma cells, providing a potential link to cancer.

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Copy and paste a formatted citation
Spandidos Publications style
WU L, LIU L, YEE A, CARBONARO-HALL D, TOLO V and HALL F: MOLECULAR-CLONING OF THE HUMAN CYCG1 GENE ENCODING A G-TYPE CYCLIN - OVEREXPRESSION IN HUMAN OSTEOSARCOMA CELLS. Oncol Rep 1: 705-711, 1994.
APA
WU, L., LIU, L., YEE, A., CARBONARO-HALL, D., TOLO, V., & HALL, F. (1994). MOLECULAR-CLONING OF THE HUMAN CYCG1 GENE ENCODING A G-TYPE CYCLIN - OVEREXPRESSION IN HUMAN OSTEOSARCOMA CELLS. Oncology Reports, 1, 705-711. https://doi.org/10.3892/or.1.4.705
MLA
WU, L., LIU, L., YEE, A., CARBONARO-HALL, D., TOLO, V., HALL, F."MOLECULAR-CLONING OF THE HUMAN CYCG1 GENE ENCODING A G-TYPE CYCLIN - OVEREXPRESSION IN HUMAN OSTEOSARCOMA CELLS". Oncology Reports 1.4 (1994): 705-711.
Chicago
WU, L., LIU, L., YEE, A., CARBONARO-HALL, D., TOLO, V., HALL, F."MOLECULAR-CLONING OF THE HUMAN CYCG1 GENE ENCODING A G-TYPE CYCLIN - OVEREXPRESSION IN HUMAN OSTEOSARCOMA CELLS". Oncology Reports 1, no. 4 (1994): 705-711. https://doi.org/10.3892/or.1.4.705
Copy and paste a formatted citation
x
Spandidos Publications style
WU L, LIU L, YEE A, CARBONARO-HALL D, TOLO V and HALL F: MOLECULAR-CLONING OF THE HUMAN CYCG1 GENE ENCODING A G-TYPE CYCLIN - OVEREXPRESSION IN HUMAN OSTEOSARCOMA CELLS. Oncol Rep 1: 705-711, 1994.
APA
WU, L., LIU, L., YEE, A., CARBONARO-HALL, D., TOLO, V., & HALL, F. (1994). MOLECULAR-CLONING OF THE HUMAN CYCG1 GENE ENCODING A G-TYPE CYCLIN - OVEREXPRESSION IN HUMAN OSTEOSARCOMA CELLS. Oncology Reports, 1, 705-711. https://doi.org/10.3892/or.1.4.705
MLA
WU, L., LIU, L., YEE, A., CARBONARO-HALL, D., TOLO, V., HALL, F."MOLECULAR-CLONING OF THE HUMAN CYCG1 GENE ENCODING A G-TYPE CYCLIN - OVEREXPRESSION IN HUMAN OSTEOSARCOMA CELLS". Oncology Reports 1.4 (1994): 705-711.
Chicago
WU, L., LIU, L., YEE, A., CARBONARO-HALL, D., TOLO, V., HALL, F."MOLECULAR-CLONING OF THE HUMAN CYCG1 GENE ENCODING A G-TYPE CYCLIN - OVEREXPRESSION IN HUMAN OSTEOSARCOMA CELLS". Oncology Reports 1, no. 4 (1994): 705-711. https://doi.org/10.3892/or.1.4.705
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