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Oncology Reports
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Print ISSN: 1021-335X Online ISSN: 1791-2431
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July 1994 Volume 1 Issue 4

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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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July 1994 Volume 1 Issue 4

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Article

MALIGNANT FIBROUS HISTIOCYTOMA OF THE SPLEEN - REPORT ON A CASE PRESENTING AS EMERGENCY

  • Authors:
    • GA DELGAUDIO
    • S PILERI
    • E SABATTINI
    • A DELGAUDIO

  • View Affiliations / Copyright

    Affiliations: UNIV BOLOGNA,SCH MED,INST GEN SURG,BOLOGNA,ITALY. UNIV BOLOGNA,INST HAEMATOL 1,SERV ANAT PATHOL,HAEMOLYMPHOPATHOL UNIT,BOLOGNA,ITALY.
  • Pages: 825-829
    |
    Published online on: July 1, 1994
       https://doi.org/10.3892/or.1.4.825
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Abstract

Among the primary malignant tumours of the spleen, fibrous histiocytoma (MFH) is extremely rare and only six cases have been reported in the literature. A splenectomy was carried out in a 22-year-old woman presenting with an acute abdomen. Imaging procedures showed a 5 cm round, heterogeneous mass in the spleen. At light microscopy the infiltrating cell population was arranged in nests or bundles with a storiform pattern. At higher magnification, most neoplastic elements were medium-sized, round or spindle-shaped, with acidophilic cytoplasm and oval or round nucleus. Mitotic figures were numerous; reactive foamy macrophages could be seen. At immunohistochemistry, in paraffin sections, there was strong positivity with the reagents against CD45, CD68, alfa-1-antichymotrypsin and vimentin. In frozen sections there was a clear-cut positivity with the antibodies EBM11 (CD68), KP1 (CD68), Ber Mac 3, anti-lysozyme and anti-vimentin. The case reported revealed morphological and immunohistochemical features consistent with MFH, of the storiform-pleomorphic variant. The clear-cut positivity for macrophage-associated molecules and for leucocyte common antigen would seem to suggest a histiocytic origin. MFH is considered an aggressive tumour, with a frequent recurrence and metastasis but our patient is alive and free of disease three years from surgery.

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Copy and paste a formatted citation
Spandidos Publications style
DELGAUDIO G, PILERI S, SABATTINI E and DELGAUDIO A: MALIGNANT FIBROUS HISTIOCYTOMA OF THE SPLEEN - REPORT ON A CASE PRESENTING AS EMERGENCY. Oncol Rep 1: 825-829, 1994.
APA
DELGAUDIO, G., PILERI, S., SABATTINI, E., & DELGAUDIO, A. (1994). MALIGNANT FIBROUS HISTIOCYTOMA OF THE SPLEEN - REPORT ON A CASE PRESENTING AS EMERGENCY. Oncology Reports, 1, 825-829. https://doi.org/10.3892/or.1.4.825
MLA
DELGAUDIO, G., PILERI, S., SABATTINI, E., DELGAUDIO, A."MALIGNANT FIBROUS HISTIOCYTOMA OF THE SPLEEN - REPORT ON A CASE PRESENTING AS EMERGENCY". Oncology Reports 1.4 (1994): 825-829.
Chicago
DELGAUDIO, G., PILERI, S., SABATTINI, E., DELGAUDIO, A."MALIGNANT FIBROUS HISTIOCYTOMA OF THE SPLEEN - REPORT ON A CASE PRESENTING AS EMERGENCY". Oncology Reports 1, no. 4 (1994): 825-829. https://doi.org/10.3892/or.1.4.825
Copy and paste a formatted citation
x
Spandidos Publications style
DELGAUDIO G, PILERI S, SABATTINI E and DELGAUDIO A: MALIGNANT FIBROUS HISTIOCYTOMA OF THE SPLEEN - REPORT ON A CASE PRESENTING AS EMERGENCY. Oncol Rep 1: 825-829, 1994.
APA
DELGAUDIO, G., PILERI, S., SABATTINI, E., & DELGAUDIO, A. (1994). MALIGNANT FIBROUS HISTIOCYTOMA OF THE SPLEEN - REPORT ON A CASE PRESENTING AS EMERGENCY. Oncology Reports, 1, 825-829. https://doi.org/10.3892/or.1.4.825
MLA
DELGAUDIO, G., PILERI, S., SABATTINI, E., DELGAUDIO, A."MALIGNANT FIBROUS HISTIOCYTOMA OF THE SPLEEN - REPORT ON A CASE PRESENTING AS EMERGENCY". Oncology Reports 1.4 (1994): 825-829.
Chicago
DELGAUDIO, G., PILERI, S., SABATTINI, E., DELGAUDIO, A."MALIGNANT FIBROUS HISTIOCYTOMA OF THE SPLEEN - REPORT ON A CASE PRESENTING AS EMERGENCY". Oncology Reports 1, no. 4 (1994): 825-829. https://doi.org/10.3892/or.1.4.825
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