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Oncology Reports
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Print ISSN: 1021-335X Online ISSN: 1791-2431
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November 1994 Volume 1 Issue 6

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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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November 1994 Volume 1 Issue 6

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Article

AMPLIFICATION ON CHROMOSOMES 1P31, 1Q21-24, 5P13-14, AND 11P12-14 IN OVARIAN-CARCINOMA DETECTED BY REVERSE CHROMOSOME PAINTING

  • Authors:
    • U FISCHER
    • HP SATTLER
    • H BONKHOFF
    • M HERRMANN
    • B WULLICH
    • EU MEESE

  • View Affiliations / Copyright

    Affiliations: UNIV SAAR,DEPT HUMAN GENET,D-66421 HOMBURG,GERMANY. UNIV SAAR,DEPT PATHOL,D-66421 HOMBURG,GERMANY. UNIV SAAR,DEPT UROL,D-66421 HOMBURG,GERMANY. HENRY FORD HOSP,DEPT SURG,DETROIT,MI 48202.
  • Pages: 1069-1073
    |
    Published online on: November 1, 1994
       https://doi.org/10.3892/or.1.6.1069
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Abstract

Recently, amplifications of several genes including c-myc, HER-2/neu, and FGF-3 (int-2) have been identified in ovarian carcinomas. We analyzed Il tumor samples from ovarian carcinoma for gene amplification using reverse chromosome painting and standard Southern blot analysis. Reverse chromosome painting detected four amplified domains on chromosome bands 1p31, 1q21-24, 5p13-14, and 11p12-14. None of the amplified domains contained genes previously reported to be amplified in ovarian carcinomas. Southern blot analysis revealed amplifications of genes HER2/neu, N-ras and H-ras. Tumor T3711 showed three independent amplifications including chromosome bands 1p31, 11p12-14 and the HER-2/neu gene (17q11.2-12).

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Copy and paste a formatted citation
Spandidos Publications style
FISCHER U, SATTLER H, BONKHOFF H, HERRMANN M, WULLICH B and MEESE E: AMPLIFICATION ON CHROMOSOMES 1P31, 1Q21-24, 5P13-14, AND 11P12-14 IN OVARIAN-CARCINOMA DETECTED BY REVERSE CHROMOSOME PAINTING. Oncol Rep 1: 1069-1073, 1994.
APA
FISCHER, U., SATTLER, H., BONKHOFF, H., HERRMANN, M., WULLICH, B., & MEESE, E. (1994). AMPLIFICATION ON CHROMOSOMES 1P31, 1Q21-24, 5P13-14, AND 11P12-14 IN OVARIAN-CARCINOMA DETECTED BY REVERSE CHROMOSOME PAINTING. Oncology Reports, 1, 1069-1073. https://doi.org/10.3892/or.1.6.1069
MLA
FISCHER, U., SATTLER, H., BONKHOFF, H., HERRMANN, M., WULLICH, B., MEESE, E."AMPLIFICATION ON CHROMOSOMES 1P31, 1Q21-24, 5P13-14, AND 11P12-14 IN OVARIAN-CARCINOMA DETECTED BY REVERSE CHROMOSOME PAINTING". Oncology Reports 1.6 (1994): 1069-1073.
Chicago
FISCHER, U., SATTLER, H., BONKHOFF, H., HERRMANN, M., WULLICH, B., MEESE, E."AMPLIFICATION ON CHROMOSOMES 1P31, 1Q21-24, 5P13-14, AND 11P12-14 IN OVARIAN-CARCINOMA DETECTED BY REVERSE CHROMOSOME PAINTING". Oncology Reports 1, no. 6 (1994): 1069-1073. https://doi.org/10.3892/or.1.6.1069
Copy and paste a formatted citation
x
Spandidos Publications style
FISCHER U, SATTLER H, BONKHOFF H, HERRMANN M, WULLICH B and MEESE E: AMPLIFICATION ON CHROMOSOMES 1P31, 1Q21-24, 5P13-14, AND 11P12-14 IN OVARIAN-CARCINOMA DETECTED BY REVERSE CHROMOSOME PAINTING. Oncol Rep 1: 1069-1073, 1994.
APA
FISCHER, U., SATTLER, H., BONKHOFF, H., HERRMANN, M., WULLICH, B., & MEESE, E. (1994). AMPLIFICATION ON CHROMOSOMES 1P31, 1Q21-24, 5P13-14, AND 11P12-14 IN OVARIAN-CARCINOMA DETECTED BY REVERSE CHROMOSOME PAINTING. Oncology Reports, 1, 1069-1073. https://doi.org/10.3892/or.1.6.1069
MLA
FISCHER, U., SATTLER, H., BONKHOFF, H., HERRMANN, M., WULLICH, B., MEESE, E."AMPLIFICATION ON CHROMOSOMES 1P31, 1Q21-24, 5P13-14, AND 11P12-14 IN OVARIAN-CARCINOMA DETECTED BY REVERSE CHROMOSOME PAINTING". Oncology Reports 1.6 (1994): 1069-1073.
Chicago
FISCHER, U., SATTLER, H., BONKHOFF, H., HERRMANN, M., WULLICH, B., MEESE, E."AMPLIFICATION ON CHROMOSOMES 1P31, 1Q21-24, 5P13-14, AND 11P12-14 IN OVARIAN-CARCINOMA DETECTED BY REVERSE CHROMOSOME PAINTING". Oncology Reports 1, no. 6 (1994): 1069-1073. https://doi.org/10.3892/or.1.6.1069
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