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Oncology Reports
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Print ISSN: 1021-335X Online ISSN: 1791-2431
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November 1994 Volume 1 Issue 6

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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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November 1994 Volume 1 Issue 6

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Article

ETOPOSIDE PHARMACOKINETICS IN A JAUNDICED INFANT WITH LETTERER-SIWE VARIANT OF LANGERHANS CELL HISTIOCYTOSIS

  • Authors:
    • PN PLOWMAN
    • SP JOEL
    • S HERMAN
  • View Affiliations / Copyright

    Affiliations: HOSP SICK CHILDREN,DEPT HAEMATOL & ONCOL,LONDON WC1,ENGLAND. ST BARTHOLOMEWS HOSP,DEPT MED ONCOL,BARRY REED ONCOL LAB,LONDON EC1,ENGLAND.
  • Pages: 1233-1234
    |
    Published online on: November 1, 1994
       https://doi.org/10.3892/or.1.6.1233
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Abstract

An infant with hepatocellular jaundice due to Langerhans cell histiocytosis was treated and responded well to intravenous etoposide. Pharmacokinetics demonstrated similar clearance and AUC data in both the jaundiced and non-jaundiced states but myelosuppression was greater when the infant was jaundiced. Children with hepatocellular jaundice require dose reductions of etoposide, despite the similar drag pharmacokinetics to the non-jaundiced state. The mechanisms involved are discussed.

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Copy and paste a formatted citation
Spandidos Publications style
PLOWMAN P, JOEL S and HERMAN S: ETOPOSIDE PHARMACOKINETICS IN A JAUNDICED INFANT WITH LETTERER-SIWE VARIANT OF LANGERHANS CELL HISTIOCYTOSIS. Oncol Rep 1: 1233-1234, 1994.
APA
PLOWMAN, P., JOEL, S., & HERMAN, S. (1994). ETOPOSIDE PHARMACOKINETICS IN A JAUNDICED INFANT WITH LETTERER-SIWE VARIANT OF LANGERHANS CELL HISTIOCYTOSIS. Oncology Reports, 1, 1233-1234. https://doi.org/10.3892/or.1.6.1233
MLA
PLOWMAN, P., JOEL, S., HERMAN, S."ETOPOSIDE PHARMACOKINETICS IN A JAUNDICED INFANT WITH LETTERER-SIWE VARIANT OF LANGERHANS CELL HISTIOCYTOSIS". Oncology Reports 1.6 (1994): 1233-1234.
Chicago
PLOWMAN, P., JOEL, S., HERMAN, S."ETOPOSIDE PHARMACOKINETICS IN A JAUNDICED INFANT WITH LETTERER-SIWE VARIANT OF LANGERHANS CELL HISTIOCYTOSIS". Oncology Reports 1, no. 6 (1994): 1233-1234. https://doi.org/10.3892/or.1.6.1233
Copy and paste a formatted citation
x
Spandidos Publications style
PLOWMAN P, JOEL S and HERMAN S: ETOPOSIDE PHARMACOKINETICS IN A JAUNDICED INFANT WITH LETTERER-SIWE VARIANT OF LANGERHANS CELL HISTIOCYTOSIS. Oncol Rep 1: 1233-1234, 1994.
APA
PLOWMAN, P., JOEL, S., & HERMAN, S. (1994). ETOPOSIDE PHARMACOKINETICS IN A JAUNDICED INFANT WITH LETTERER-SIWE VARIANT OF LANGERHANS CELL HISTIOCYTOSIS. Oncology Reports, 1, 1233-1234. https://doi.org/10.3892/or.1.6.1233
MLA
PLOWMAN, P., JOEL, S., HERMAN, S."ETOPOSIDE PHARMACOKINETICS IN A JAUNDICED INFANT WITH LETTERER-SIWE VARIANT OF LANGERHANS CELL HISTIOCYTOSIS". Oncology Reports 1.6 (1994): 1233-1234.
Chicago
PLOWMAN, P., JOEL, S., HERMAN, S."ETOPOSIDE PHARMACOKINETICS IN A JAUNDICED INFANT WITH LETTERER-SIWE VARIANT OF LANGERHANS CELL HISTIOCYTOSIS". Oncology Reports 1, no. 6 (1994): 1233-1234. https://doi.org/10.3892/or.1.6.1233
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