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Oncology Reports
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Print ISSN: 1021-335X Online ISSN: 1791-2431
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February 2004 Volume 11 Issue 2

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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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February 2004 Volume 11 Issue 2

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Article

In vitro comparison of Essiac® and Flor-Essence® on human tumor cell lines

  • Authors:
    • Joseph Tai
    • Susan Cheung
    • Stephen Wong
    • Christopher Lowe
  • View Affiliations / Copyright

    Affiliations: BC's Research Institute for Children's and Women's Health, Vancouver, British Columbia, V5Z 4H4, Canada. jtai@interchange.ubc.ca
  • Pages: 471-476
    |
    Published online on: February 1, 2004
       https://doi.org/10.3892/or.11.2.471
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Abstract

Essiac® (ES) and Flor-Essence® (FE) are two herbal teas widely taken by North American cancer patients during chemo- and radiation therapy. In vitro studies on the antiproliferative and differentiation inducing activities of these teas were performed. ES and FE showed negligible antiproliferative activity on Jurkat leukemia cells. Both herbal teas inhibited 50% (IC50) of MCF7 breast cancer cell growth at 1/10 dilution. The IC50 was about 1/40 and 1/10 dilution of FE and ES respectively for MDA-MB-468 human breast cancer cells. The IC50 for HL60 cells was at 1/10 dilution of FE and less than 1/10 dilution of ES. ES at 1/10 dilution induced expression of non-specific esterase in 16% of HL60 cells, compared to about 5% in FE treated cells and untreated controls. ES treatment of HL60 cells induced 47-67% nitroblue tetrazolium positive staining cells compared to 24.6±3.1% in cells treated with 1/10 dilution of FE. Flow cytometry analysis showed that both ES and FE treatment between 1/10 and 1/100 dilutions only slightly affected the cell cycle progression of MCF7, MDA-MB-468, Jurkat and HL60 cells. Our data show that both ES and FE herbal teas demonstrated antiproliferative and differentiation inducting properties in vitro only at high concentrations. Further research is needed to elucidate the in vivo activities.

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Copy and paste a formatted citation
Spandidos Publications style
Tai J, Cheung S, Wong S and Lowe C: In vitro comparison of Essiac® and Flor-Essence® on human tumor cell lines. Oncol Rep 11: 471-476, 2004.
APA
Tai, J., Cheung, S., Wong, S., & Lowe, C. (2004). In vitro comparison of Essiac® and Flor-Essence® on human tumor cell lines. Oncology Reports, 11, 471-476. https://doi.org/10.3892/or.11.2.471
MLA
Tai, J., Cheung, S., Wong, S., Lowe, C."In vitro comparison of Essiac® and Flor-Essence® on human tumor cell lines". Oncology Reports 11.2 (2004): 471-476.
Chicago
Tai, J., Cheung, S., Wong, S., Lowe, C."In vitro comparison of Essiac® and Flor-Essence® on human tumor cell lines". Oncology Reports 11, no. 2 (2004): 471-476. https://doi.org/10.3892/or.11.2.471
Copy and paste a formatted citation
x
Spandidos Publications style
Tai J, Cheung S, Wong S and Lowe C: In vitro comparison of Essiac® and Flor-Essence® on human tumor cell lines. Oncol Rep 11: 471-476, 2004.
APA
Tai, J., Cheung, S., Wong, S., & Lowe, C. (2004). In vitro comparison of Essiac® and Flor-Essence® on human tumor cell lines. Oncology Reports, 11, 471-476. https://doi.org/10.3892/or.11.2.471
MLA
Tai, J., Cheung, S., Wong, S., Lowe, C."In vitro comparison of Essiac® and Flor-Essence® on human tumor cell lines". Oncology Reports 11.2 (2004): 471-476.
Chicago
Tai, J., Cheung, S., Wong, S., Lowe, C."In vitro comparison of Essiac® and Flor-Essence® on human tumor cell lines". Oncology Reports 11, no. 2 (2004): 471-476. https://doi.org/10.3892/or.11.2.471
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