Diffuse large B-cell primary gastric lymphoma treated successfully with the CD20 monoclonal antibody (rituximab): A case with severe liver dysfunction due to liver cirrhosis and hepatocellular carcinoma

  • Authors:
    • Seiji Nakai
    • Tsutomu Masaki
    • Takamichi Shintani
    • Akihiro Deguchi
    • Yasuhiko Kimura
    • Takashi Himoto
    • Kazutaka Kurokohchi
    • Seishiro Watanabe
    • Shigeki Kuriyama
  • View Affiliations

  • Published online on: June 1, 2005     https://doi.org/10.3892/or.13.6.1065
  • Pages: 1065-1068
Metrics: Total Views: 0 (Spandidos Publications: | PMC Statistics: )
Total PDF Downloads: 0 (Spandidos Publications: | PMC Statistics: )


Abstract

Primary gastric lymphoma is relatively rare in the scope of gastric malignancies. Here we report a case of diffuse large B-cell primary gastric lymphoma treated successfully with the CD20 monoclonal antibody, rituximab, alone. Because the patient had a complication of severe liver dysfunction due to hepatitis C virus induced-liver cirrhosis and hepatocellular carcinoma, it was difficult to treat the primary gastric lymphoma using standard therapy such as surgical resection and cocktail chemotherapy. Therefore, rituximab was administered to the patient, resulting in complete remission of the primary gastric lymphoma. This case indicates that monotherapy using only rituximab may be a promising option for the treatment of patients with diffuse large B-cell lymphoma accompanied by severe liver dysfunction.

Related Articles

Journal Cover

June 2005
Volume 13 Issue 6

Print ISSN: 1021-335X
Online ISSN:1791-2431

Sign up for eToc alerts

Recommend to Library

Copy and paste a formatted citation
x
Spandidos Publications style
Nakai S, Masaki T, Shintani T, Deguchi A, Kimura Y, Himoto T, Kurokohchi K, Watanabe S and Kuriyama S: Diffuse large B-cell primary gastric lymphoma treated successfully with the CD20 monoclonal antibody (rituximab): A case with severe liver dysfunction due to liver cirrhosis and hepatocellular carcinoma . Oncol Rep 13: 1065-1068, 2005
APA
Nakai, S., Masaki, T., Shintani, T., Deguchi, A., Kimura, Y., Himoto, T. ... Kuriyama, S. (2005). Diffuse large B-cell primary gastric lymphoma treated successfully with the CD20 monoclonal antibody (rituximab): A case with severe liver dysfunction due to liver cirrhosis and hepatocellular carcinoma . Oncology Reports, 13, 1065-1068. https://doi.org/10.3892/or.13.6.1065
MLA
Nakai, S., Masaki, T., Shintani, T., Deguchi, A., Kimura, Y., Himoto, T., Kurokohchi, K., Watanabe, S., Kuriyama, S."Diffuse large B-cell primary gastric lymphoma treated successfully with the CD20 monoclonal antibody (rituximab): A case with severe liver dysfunction due to liver cirrhosis and hepatocellular carcinoma ". Oncology Reports 13.6 (2005): 1065-1068.
Chicago
Nakai, S., Masaki, T., Shintani, T., Deguchi, A., Kimura, Y., Himoto, T., Kurokohchi, K., Watanabe, S., Kuriyama, S."Diffuse large B-cell primary gastric lymphoma treated successfully with the CD20 monoclonal antibody (rituximab): A case with severe liver dysfunction due to liver cirrhosis and hepatocellular carcinoma ". Oncology Reports 13, no. 6 (2005): 1065-1068. https://doi.org/10.3892/or.13.6.1065