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Oncology Reports
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Print ISSN: 1021-335X Online ISSN: 1791-2431
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June 2005 Volume 13 Issue 6

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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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June 2005 Volume 13 Issue 6

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Article

Multimodality therapy and significance of serum CYFRA21-1 for thymic carcinoma

  • Authors:
    • Makoto Suzuki
    • Soichiro Ando
    • Tomohiko Iida
    • Takehiko Fujisawa
    • Hideki Kimura

  • View Affiliations / Copyright

    Affiliations: Division of Thoracic Diseases, Chiba Cancer Center, 666-2 Nitona-cho, Chuoh-ku, Chiba 260-8717, Japan. smakoto@chiba-cc.jp
  • Pages: 1127-1131
    |
    Published online on: June 1, 2005
       https://doi.org/10.3892/or.13.6.1127
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Abstract

Thymic carcinoma is a rare mediastinal neoplasm with a poor prognosis due to delayed diagnosis and highly malignant behavior. To evaluate 7 serum tumor markers and the outcome of treatment, 11 stage III-IVb thymic carcinomas undergoing multimodality treatment were reviewed. High levels of serum CYFRA21-1 were detected in 5 patients (45%) and correlated with the progression of disease. Of the patients, 6 underwent surgery. The median survival time was 38.4 months, and the 5-year survival rate was 15.6%. The metastatic stage (IVb) and treatment without resection were significantly associated with poorer overall survival (p=0.0034 and p=0.0041, respectively). Our data demonstrated that serum CYFRA21-1 may represent a potential new biomarker in thymic carcinoma. Stage may provide a basis for prognosis in stage III-IVb thymic carcinoma, and resection is one of the most important parts of multimodality treatment for advanced thymic carcinoma. Effective neoadjuvant treatment is therefore essential.

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Copy and paste a formatted citation
Spandidos Publications style
Suzuki M, Ando S, Iida T, Fujisawa T and Kimura H: Multimodality therapy and significance of serum CYFRA21-1 for thymic carcinoma. Oncol Rep 13: 1127-1131, 2005.
APA
Suzuki, M., Ando, S., Iida, T., Fujisawa, T., & Kimura, H. (2005). Multimodality therapy and significance of serum CYFRA21-1 for thymic carcinoma. Oncology Reports, 13, 1127-1131. https://doi.org/10.3892/or.13.6.1127
MLA
Suzuki, M., Ando, S., Iida, T., Fujisawa, T., Kimura, H."Multimodality therapy and significance of serum CYFRA21-1 for thymic carcinoma". Oncology Reports 13.6 (2005): 1127-1131.
Chicago
Suzuki, M., Ando, S., Iida, T., Fujisawa, T., Kimura, H."Multimodality therapy and significance of serum CYFRA21-1 for thymic carcinoma". Oncology Reports 13, no. 6 (2005): 1127-1131. https://doi.org/10.3892/or.13.6.1127
Copy and paste a formatted citation
x
Spandidos Publications style
Suzuki M, Ando S, Iida T, Fujisawa T and Kimura H: Multimodality therapy and significance of serum CYFRA21-1 for thymic carcinoma. Oncol Rep 13: 1127-1131, 2005.
APA
Suzuki, M., Ando, S., Iida, T., Fujisawa, T., & Kimura, H. (2005). Multimodality therapy and significance of serum CYFRA21-1 for thymic carcinoma. Oncology Reports, 13, 1127-1131. https://doi.org/10.3892/or.13.6.1127
MLA
Suzuki, M., Ando, S., Iida, T., Fujisawa, T., Kimura, H."Multimodality therapy and significance of serum CYFRA21-1 for thymic carcinoma". Oncology Reports 13.6 (2005): 1127-1131.
Chicago
Suzuki, M., Ando, S., Iida, T., Fujisawa, T., Kimura, H."Multimodality therapy and significance of serum CYFRA21-1 for thymic carcinoma". Oncology Reports 13, no. 6 (2005): 1127-1131. https://doi.org/10.3892/or.13.6.1127
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