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Oncology Reports
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Print ISSN: 1021-335X Online ISSN: 1791-2431
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July 2005 Volume 14 Issue 1

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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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July 2005 Volume 14 Issue 1

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Article

Inhibitory effect of glycolipids from spinach on in vitro and ex vivo angiogenesis

  • Authors:
    • Kiminori Matsubara
    • Hiroaki Matsumoto
    • Yoshiyuki Mizushina
    • Masaharu Mori
    • Nobuyoshi Nakajima
    • Michiko Fuchigami
    • Hiromi Yoshida
    • Takahiko Hada
  • View Affiliations / Copyright

    Affiliations: Department of Nutritional Science, Faculty of Health and Welfare Science, Okayama Prefectural University, 111 Kuboki, Soja, Okayama 719-1197, Japan. kmatsuba@fhw.oka-pu.ac.jp
  • Pages: 157-160
    |
    Published online on: July 1, 2005
       https://doi.org/10.3892/or.14.1.157
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Abstract

Anti-cancer activity of some glycolipids from animals and plants has been demonstrated, although it was unknown whether the glycolipids had anti-angiogenic activity. The effects of the purified three glycolipids, monogalactosyl diacylglycerol (MGDG), digalactosyl diacylglycerol (DGDG), and sulfoquinovosyl diacylglycerol (SQDG) from the green vegetable spinach (Spinacia oleracea L.) were examined on in vitro and ex vivo angiogenesis models. MGDG and SQDG suppressed microvessel growth in an ex vivo angiogenesis model using a rat aortic ring. The glycolipids inhibited human umbilical vein endothelial cell (HVUEC) tube formation on a reconstituted basement membrane and HUVEC proliferation. These results demonstrate that glycolipids from spinach would suppress tumor growth by suppressing angiogenesis and might be candidates for anti-cancer or anti-angiogenic materials.

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Copy and paste a formatted citation
Spandidos Publications style
Matsubara K, Matsumoto H, Mizushina Y, Mori M, Nakajima N, Fuchigami M, Yoshida H and Hada T: Inhibitory effect of glycolipids from spinach on in vitro and ex vivo angiogenesis. Oncol Rep 14: 157-160, 2005.
APA
Matsubara, K., Matsumoto, H., Mizushina, Y., Mori, M., Nakajima, N., Fuchigami, M. ... Hada, T. (2005). Inhibitory effect of glycolipids from spinach on in vitro and ex vivo angiogenesis. Oncology Reports, 14, 157-160. https://doi.org/10.3892/or.14.1.157
MLA
Matsubara, K., Matsumoto, H., Mizushina, Y., Mori, M., Nakajima, N., Fuchigami, M., Yoshida, H., Hada, T."Inhibitory effect of glycolipids from spinach on in vitro and ex vivo angiogenesis". Oncology Reports 14.1 (2005): 157-160.
Chicago
Matsubara, K., Matsumoto, H., Mizushina, Y., Mori, M., Nakajima, N., Fuchigami, M., Yoshida, H., Hada, T."Inhibitory effect of glycolipids from spinach on in vitro and ex vivo angiogenesis". Oncology Reports 14, no. 1 (2005): 157-160. https://doi.org/10.3892/or.14.1.157
Copy and paste a formatted citation
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Spandidos Publications style
Matsubara K, Matsumoto H, Mizushina Y, Mori M, Nakajima N, Fuchigami M, Yoshida H and Hada T: Inhibitory effect of glycolipids from spinach on in vitro and ex vivo angiogenesis. Oncol Rep 14: 157-160, 2005.
APA
Matsubara, K., Matsumoto, H., Mizushina, Y., Mori, M., Nakajima, N., Fuchigami, M. ... Hada, T. (2005). Inhibitory effect of glycolipids from spinach on in vitro and ex vivo angiogenesis. Oncology Reports, 14, 157-160. https://doi.org/10.3892/or.14.1.157
MLA
Matsubara, K., Matsumoto, H., Mizushina, Y., Mori, M., Nakajima, N., Fuchigami, M., Yoshida, H., Hada, T."Inhibitory effect of glycolipids from spinach on in vitro and ex vivo angiogenesis". Oncology Reports 14.1 (2005): 157-160.
Chicago
Matsubara, K., Matsumoto, H., Mizushina, Y., Mori, M., Nakajima, N., Fuchigami, M., Yoshida, H., Hada, T."Inhibitory effect of glycolipids from spinach on in vitro and ex vivo angiogenesis". Oncology Reports 14, no. 1 (2005): 157-160. https://doi.org/10.3892/or.14.1.157
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