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Print ISSN: 1021-335X Online ISSN: 1791-2431
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
July 2005 Volume 14 Issue 1

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review

The role of heparanase in gastrointestinal cancer (Review)

Yoshio Naomoto, Munenori Takaoka, Takaomi Okawa, Tetsuji Nobuhisa, Mehmet Gunduz, Noriaki Tanaka
Pages: 3-8
Published online on: 01 July 2005

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Article

Effects of vanadium complexes on cell growth of human leukemia cells and protein-DNA interactions

Ilaria Lampronti, Nicoletta Bianchi, Monica Borgatti, Enrica Fabbri, Leonardo Vizziello, Mahmud Tareq Hassan Khan, Arjumand Ather, Dan Brezena, Mohammad Mahroof Tahir, Roberto Gambari
Pages: 9-15
Published online on: 01 July 2005

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Article

Loss of expression of oestrogen receptor β in colon cancer and its association with Dukes' staging

N. Jassam, S.M. Bell, V. Speirs, P. Quirke
Pages: 17-21
Published online on: 01 July 2005

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Article

Detailed chromosomal characterization of the breast cancer cell line MCF7 with special focus on the expression of the serine-threonine kinase 15

Alexandra Klein, Volker Jung, Klaus D. Zang, Wolfram Henn, Mathias Montenarh, Sabine Kartarius, Wolf-Ingo Steudel, Steffi Urbschat
Pages: 23-31
Published online on: 30 June 2005

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Article

Correlations between antitumor activities of fluoropyrimidines and DPD activity in lung tumor xenografts

Teiji Takechi, Hiroyuki Okabe, Kazumasa Ikeda, Akio Fujioka, Fumio Nakagawa, Hideyuki Ohshimo, Kenji Kitazato, Masakazu Fukushima
Pages: 33-39
Published online on: 01 July 2005

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Article

Differentiation and apoptosis in human malignant melanoma G-361 cells induced by 2-aminophenoxazine-3-one

Shigetaka Shimizu, Mamoru Suzuki, Keisuke Miyazawa, Tomohisa Yokoyama, Kazuma Ohyashiki, Kaori Miyazaki, Akihisa Abe, Akio Tomoda
Pages: 41-46
Published online on: 01 July 2005

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Article

Multiple endocrine neoplasia type 1 gene mutations in sporadic gastrinomas in Japan

Junichiro Kawamura, Yutaka Shimada, Izumi Komoto, Hiroomi Okamoto, Atsushi Itami, Ryuichiro Doi, Koji Fujimoto, Shinji Kosugi, Masayuki Imamura
Pages: 47-52
Published online on: 30 June 2005

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Article

Enhancement of antitumor activity of 5'-deoxy-5-fluorouridine (Furtulon®) by taxane in human gastric cancer xenografts

Noriaki Sawada, Taeko Nose, Tohru Ishikawa, Tanaka Yutaka
Pages: 53-57
Published online on: 01 July 2005

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Article

KAI1 inhibits anchorage-dependent and -independent pancreatic cancer cell growth

Xiao-Zhong Guo, Jian-Hua Xu, Min-pei Liu, Jörg Kleeff, Choon-Kiat Ho, Li-Nan Ren, Hong-Yu Li, Jörg Köninger, Zhong-Min Cui, Di Wang, Chun-Yan Wu, Jia-Jun Zhao, Helmut Friess
Pages: 59-63
Published online on: 01 July 2005

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Article

Analysis of progressively overexpressed genes in tumorigenesis of colorectal cancers using cDNA microarray

Jaw-Yuan Wang, Ching-Sheng Yeh, Wen-Shyong Tzou, Jan-Sing Hsieh, Fang-Ming Chen, Chien-Yu Lu, Fang-Jung Yu, Tian-Lu Cheng, Tsung-Jen Huang, Shiu-Ru Lin
Pages: 65-72
Published online on: 01 July 2005

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Article

5-Lipoxygenase inhibitors attenuate growth of human renal cell carcinoma and induce apoptosis through arachidonic acid pathway

Masahide Matsuyama, Rikio Yoshimura, Makoto Mitsuhashi, Kenji Tsuchida, Yoshiaki Takemoto, Yutaka Kawahito, Hajime Sano, Tatsuya Nakatani
Pages: 73-79
Published online on: 01 July 2005

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Article

Microvascular density, vascular endothelial growth factor immunoreactivity in tumor cells, vessel diameter and intussusceptive microvascular growth in primary melanoma

Domenico Ribatti, Beatrice Nico, Carlo Floris, Domenica Mangieri, Franca Piras, Maria Grazia Ennas, Angelo Vacca, Paola Sirigu
Pages: 81-84
Published online on: 01 July 2005

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Article

Structure-based assessment of BRCA1 and BRCA2 mutations in a small Spanish population

J. Salgado, N. Zabalegui, F. García-Amigot, M. C. Gil, M. S. González, J. García-Foncillas
Pages: 85-88
Published online on: 01 July 2005

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Article

Loss of basement membrane heparan sulfate expression is associated with pelvic lymph node metastasis in invasive cervical cancer

Junichi Kodama, Yasuhiro Shinyo, Hasengaowa, Tomoyuki Kusumoto, Noriko Seki, Keiichiro Nakamura, Atsushi Hongo, Yuji Hiramatsu
Pages: 89-92
Published online on: 01 July 2005

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Article

Expression of insulin-like growth factor-I receptor, estrogen receptor α, Bcl-2 and Bax proteins in human breast cancer

Mariusz Koda, Wojciech Przystupa, Katarzyna Jarzabek, Andrzej Wincewicz, Luiza Kanczuga-Koda, Jakub Tomaszewski, Mariola Sulkowska, Slawomir Wolczynski, Stanislaw Sulkowski
Pages: 93-98
Published online on: 01 July 2005

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Article

Non-anti-coagulant heparin inhibits metastasis but not primary tumor growth

Michael Kragh, Lise Binderup, Pernille-Julia Vig Hjarnaa, Erik Bramm, Kristian B. Johansen, Christian Frimundt Petersen
Pages: 99-104
Published online on: 01 July 2005

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Review

Urokinase-type plasminogen activator system and breast cancer (Review)

Bo Han, Misa Nakamura, Ichiro Mori, Yasushi Nakamura, Kennichi Kakudo
Pages: 105-112
Published online on: 01 July 2005

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Article

Flow cytometric analysis of circulating dendritic cell subsets and intracellular cytokine production in advanced breast cancer patients

Silvia Ferrari, Fabio Malugani, Bianca Rovati, Camillo Porta, Alberto Riccardi, Marco Danova
Pages: 113-120
Published online on: 01 July 2005

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Article

Cellular kinetics and K-ras codon 12 mutations according to histomorphometric type of colorectal polyps with epithelial serrated proliferation

Shigeharu Hamatani, Ryo Wada, Ayako Morita, Chikako Hasegawa, Aki Mitsuda, Tsutomu Hatori, Hiroko Nonaka, Keiji Takahashi, Shina Gomi, Kazutoshi Shibuya
Pages: 121-127
Published online on: 01 July 2005

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Article

A multicenter randomized study comparing 5-fluorouracil continuous infusion (ci) plus 1-hexylcarbamoyl-5-fluorouracil and 5-FU ci alone in colorectal cancer

Kenjiro Kotake, Yasuo Ohashi, Susumu Kodaira, Yasuo Koyama, East-Japan Colorectal Cancer Chemotherapy Study Group
Pages: 129-134
Published online on: 01 July 2005

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Article

Chemotherapy under cachectic conditions and the possibility of cachexia-controlled chemotherapy

Yutaka Takahashi, Kazuo Yasumoto, Masayoshi Mai
Pages: 135-140
Published online on: 01 July 2005

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Article

K252a inhibits proliferation of ovarian cancer cells by upregulating p21WAF1

Noriyuki Takai, Tami Ueda, Masakazu Nishida, Kaei Nasu, Junichiro Fukuda, Isao Miyakawa
Pages: 141-143
Published online on: 01 July 2005

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Article

Induction of S phase cell arrest and caspase activation by polysaccharide peptide isolated from Coriolus versicolor enhanced the cell cycle dependent activity and apoptotic cell death of doxorubicin and etoposide, but not cytarabine in HL-60 cells

Kenrie Pui-Yan Hui, Wai-Hung Sit, Jennifer Man-Fan Wan
Pages: 145-155
Published online on: 01 July 2005

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Article

Inhibitory effect of glycolipids from spinach on in vitro and ex vivo angiogenesis

Kiminori Matsubara, Hiroaki Matsumoto, Yoshiyuki Mizushina, Masaharu Mori, Nobuyoshi Nakajima, Michiko Fuchigami, Hiromi Yoshida, Takahiko Hada
Pages: 157-160
Published online on: 01 July 2005

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Article

Expression of nerve growth factor receptors and their prognostic value in human pancreatic cancer

Yong Zhang, Chengxue Dang, Qingyong Ma, Yasuyuki Shimahara
Pages: 161-171
Published online on: 01 July 2005

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Article

Occult neoplastic cells and malignant micro-aggregates in lymph node sinuses: Review and hypothesis

Masaya Mukai
Pages: 173-175
Published online on: 01 July 2005

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Article

Combination of 5-deoxy-5-fluorouridine and tamoxifen show cell-type specific antagonistic and cooperative effects on cytotoxicity in human mammary carcinoma cells

Aliccia Bollig, Qian-qian Du, Shing-tzu Fan, Ben Yu, Fazlul H. Sarkar, Joshua Liao
Pages: 177-183
Published online on: 01 July 2005

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Article

Polymorphism of the MUC1 mucin gene is associated with susceptibility to lung adenocarcinoma and poor prognosis

Kazuhiro Mitsuta, Akihito Yokoyama, Keiichi Kondo, Masamitsu Nakajima, Ken-ichi Arita, Nobuoki Kohno
Pages: 185-189
Published online on: 01 July 2005

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Article

Methylation of the MLH1 gene in hematological malignancies

Masahide Matsushita, Seisho Takeuchi, Yang Yang, Norihide Yoshino, Kunihiro Tsukasaki, Hirokuni Taguchi, H. Phillip Koeffler, Hiromi Seo
Pages: 191-194
Published online on: 01 July 2005

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Article

The extending range of the tumor is a more suitable predictive risk factor for lymph node metastases than the location of the deepest tumor invasion in distal thoracic esophageal and cardiac cancer

Atsushi Shiozaki, Hirosumi Itoi, Yuji Ueda, Teruhisa Sonoyama, Hisakazu Yamagishi
Pages: 195-199
Published online on: 01 July 2005

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Article

Evaluation of 5-fluorouracil applicability by multi-point collagen gel droplet embedded drug sensitivity test

Takumi Ochiai, Kazuhiko Nishimura, Hajime Noguchi, Masayuki Kitajima, Yuko Tsuruoka, Yuka Takahashi
Pages: 201-205
Published online on: 01 July 2005

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Article

Efficacy of platinum-based chemotherapy after cranial radiation in patients with brain metastasis from non-small cell lung cancer

Dae-Young Kim, Keun-Wook Lee, Tak Yun, Dong-Wan Kim, Tae-You Kim, Dae Seog Heo, Yung-Jue Bang, Noe Kyeong Kim
Pages: 207-211
Published online on: 01 July 2005

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Article

Combination of copper-chelating agent, trientine, and methotrexate attenuates colorectal carcinoma development and angiogenesis in mice

Hitoshi Yoshiji, Junichi Yoshii, Shigeki Kuriyama, Yasuhide Ikenaka, Ryuichi Noguchi, Koji Yanase, Tadashi Namisaki, Mitsuteru Kitade, Masaharu Yamazaki, Hiroshi Fukui
Pages: 213-218
Published online on: 30 June 2005

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Article

Simple mucin-type cancer associated antigens are pre-cancerous biomarkers during 1,2-dimethylhydrazine-induced rat colon carcinogenesis

Edgardo Berriel, Marcelo Hill, Juan J. Barcia, Luis Ubillos, Mariela Gonzalez, Gisselle Detjen, Mariella Rondan, Héctor Navarrete, Eduardo Osinaga
Pages: 219-227
Published online on: 01 July 2005

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Article

Differentially expressed genes associated with human lung cancer

Wei Xiao, Manuela Pacyna-Gengelbach, Karsten Schlüns, Qian An, Yanning Gao, Shujun Cheng, Iver Petersen
Pages: 229-234
Published online on: 30 June 2005

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Article

Measurement of plasminogen activator system components in plasma and tumor tissue extracts obtained from patients with breast cancer: An EORTC Receptor and Biomarker Group collaboration

N. Grebenchtchikov, T. M. Maguire, R. Riisbro, A. Geurts-Moespot, N. O'Donovan, M. Schmitt, G. McGreal, E. McDermott, N. O'Higgins, N. Brünner, C. G.J. Sweep, M. J. Duffy
Pages: 235-239
Published online on: 01 July 2005

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Article

Prognostic and predictive relevance of microsatellite instability in colorectal cancer

Iana Storojeva, Jean-Louis Boulay, Karl Heinimann, Pierluigi Ballabeni, Luigi Terracciano, Urban Laffer, Gabriele Mild, Richard Herrmann, Christoph Rochlitz
Pages: 241-249
Published online on: 30 June 2005

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Article

Qualitative and quantitative analysis of angiogenetic factors in transitional cell bladder carcinoma: Relationship with clinical course at 10 years follow-up

Riccardo Bartoletti, Tommaso Cai, Gabriella Nesi, Iacopo Sardi, Michelangelo Rizzo
Pages: 251-255
Published online on: 01 July 2005

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Article

Systemic inflammation correlates with increased expression of skeletal muscle ubiquitin but not uncoupling proteins in cancer cachexia

Cornelis H.C. Dejong, Sylvia Busquets, Alastair G.W. Moses, Patrick Schrauwen, Jim A. Ross, Josep M. Argiles, Kenneth C.H. Fearon
Pages: 257-263
Published online on: 01 July 2005

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Article

A high-fat diet enhances the inhibitory effect of dietary vitamin B6 on colon cell proliferation in mice

Shun-Ichiro Komatsu, Masami Isobe, Noriyuki Yanaka, Norihisa Kato
Pages: 265-269
Published online on: 01 July 2005

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Article

Human DNA topoisomerase II-α expression in laparoscopically treated renal cell carcinoma

Yoram Dekel, Thomas Frede, Valentina Kugel, Gad Neumann, Jens Rassweiler, Rumelia Koren
Pages: 271-274
Published online on: 01 July 2005

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Article

Induction of apoptosis in human ovarian epithelial cancer cells by antisurvivin oligonucleotides

Xiangyi Ma, Shixuan Wang, Jianfeng Zhou, Hui Xing, Gang Xu, Beibei Wang, Gang Chen, Yun-Ping Lu, Ding Ma
Pages: 275-279
Published online on: 01 July 2005

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Article

Cisplatin sensitization by concurrent mild hyperthermia in parental and mutant cell lines deficient in homologous recombination and non-homologous endjoining repair

G. P. Raaphorst, L. F. Li, D. P. Yang, J.-M. Leblanc
Pages: 281-285
Published online on: 01 July 2005

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Article

Comparative genomics on FGF20 orthologs

Masuko Katoh, Masaru Katoh, Yuriko Katoh
Pages: 287-290
Published online on: 30 June 2005

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Article

Comparative genomics on Fgf11 orthologs.

Yuriko Katoh, Masaru Katoh
Pages: 291-295
Published online on: 01 July 2005

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Journal Cover
January-2026 Volume 55 Issue 1

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review Open Access

Harnessing ferroptosis for cancer therapy: Mechanisms and therapeutic strategies (Review)

Nabil Mouawad, Nour El Jaafari, Mirvat El Sibai, Ralph J. Abi-Habib
Article Number: 24
Published online on: 24 November 2025

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Expression of Concern Open Access

[Expression of Concern] Promoter methylation of death‑associated protein kinase and its role in irradiation response in cervical cancer

Rebecca Ching-Yu Leung, Stephanie Si Liu, Kelvin Yuen-Kwong Chan, Kar-Fai Tam, Kar-Loen Chan, Ling-Chui Wong, Hextan Yuen-Sheung Ngan
Article Number: 23
Published online on: 24 November 2025

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Article Open Access

Oxaliplatin resistance in pancreatic ductal adenocarcinoma is non‑significantly mediated by diminished drug uptake but is highly linked to a poor apoptotic response to the cytotoxic threat

Hellen Röttgen, Lana Theurer, Teresa Peccerella, Ketaki Sandu, Johanna Weiss, Jürgen Burhenne, John P. Neoptolemos, Beate Köberle, Dirk Theile
Article Number: 22
Published online on: 19 November 2025

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Correction Open Access

[Corrigendum] Src homology phosphotyrosyl phosphatase 2 mediates cisplatin‑related drug resistance by inhibiting apoptosis and activating the Ras/PI3K/Akt1/survivin pathway in lung cancer cells

Chunlan Tang, Hu Luo, Dan Luo, Heping Yang, Xiangdong Zhou
Article Number: 21
Published online on: 19 November 2025

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Article Open Access

S100B drives glioblastoma invasion and migration through TGF‑β2‑mediated epithelial‑mesenchymal transition

Xuemei Liao, Yuan Xu, Honghong Zhou, Qin Yi, Shifang Dong, Bin Tan
Article Number: 20
Published online on: 19 November 2025

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Review Open Access

Role of the SOX family in non‑small cell lung cancer: Molecular mechanisms and therapeutic implications (Review)

Kaiwei Wang, Yaoqi Li, Zhening Guo, Lin Song, Xiaoliang Ding, Linsheng Liu, Tao Hu, Yicong Bian, Chenrong Huang, Liyan Miao
Article Number: 19
Published online on: 18 November 2025

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Retraction Open Access

[Retracted] MicroRNA‑18a enhances the radiosensitivity of cervical cancer cells by promoting radiation‑induced apoptosis

Sha Liu, Xiaofen Pan, Qin Yang, Lu Wen, Yao Jiang, Yingchao Zhao, Guiling Li
Article Number: 18
Published online on: 17 November 2025

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Review Open Access

Role of histone deacetylases in blood cancer: Exploring peptide‑based inhibitors as therapeutic strategies for leukemia treatment (Review)

Yaneenart Suwanwong, Phornthip Ploensil
Article Number: 17
Published online on: 14 November 2025

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Review Open Access

The multidimensional regulatory network of the PD‑1/PD‑L1 axis in the esophageal squamous cell carcinoma microenvironment: Implications for novel combination therapies and precision immunotherapy (Review)

Haoyue Lai, Lu Qi, Zhixuan Lin, Zhongwen Li
Article Number: 16
Published online on: 13 November 2025

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Review Open Access

From modification to malignancy: Bridging acetylation mechanisms and therapeutic innovations in melanoma (Review)

Jingwen Wu, Xuxia Cai, Zimo Zhu, Xiahong Li, Kaoyuan Zhang, Chenchen Wu, Bo Yu, Cong Huang
Article Number: 15
Published online on: 12 November 2025

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Retraction Open Access

[Retracted] MicroRNA‑92b promotes tumor growth and activation of NF‑κB signaling via regulation of NLK in oral squamous cell carcinoma

Zhiming Liu, Cynthia Diep, Tiantian Mao, Li Huang, Robert Merrill, Zhouwen Zhang, Youjian Peng
Article Number: 14
Published online on: 11 November 2025

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Article Open Access

C‑terminal HSP90 inhibitor NCT‑58 impairs the cancer stem‑like phenotype and enhances chemotherapy efficacy in TNBC

Eunsun Jung, Yoon-Jae Kim, Kyoungmin Lee, Seojin Jang, Soeun Park, Eunhye Oh, Minsu Park, Seongjae Kim, Dongmi Ko, Yong Koo Kang, Kee Dal Nam, Lee Farrand, Cong-Truong Nguyen, Minh Thanh La, Jihyae Ann, Jeewoo Lee, Ji Young Kim, Jae Hong Seo
Article Number: 13
Published online on: 11 November 2025

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Correction Open Access

[Corrigendum] Compound 225# inhibits the proliferation of human colorectal cancer cells by promoting cell cycle arrest and apoptosis induction

Xiaoxue Zhang, Liujun He, Yong Li, Yifei Qiu, Wujing Hu, Wanying Lu, Huihui Du, Donglin Yang
Article Number: 12
Published online on: 06 November 2025

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Review Open Access

Immune system, inflammatory response, and regulated cell death in breast cancer research (Review)

Guangyao Li, Binghui Jin, Jialin Zhou, Shifeng Fang, Zhe Fan
Article Number: 11
Published online on: 05 November 2025

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Retraction Open Access

[Retracted] Uvangoletin induces mitochondria‑mediated apoptosis in HL‑60 cells in vitro and in vivo without adverse reactions of myelosuppression, leucopenia and gastrointestinal tract disturbances

Zhuanzhen Zheng, Zhenhua Qiao, Rong Gong, Yalin Wang, Yiqun Zhang, Yanping Ma, Li Zhang, Yujin Lu, Bo Jiang, Guoxia Li, Chunxia Dong, Wenliang Chen
Article Number: 10
Published online on: 03 November 2025

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Article Open Access

Characterization of the anticancer effect of mebendazole and its interaction with standard cytotoxic drugs in patient tumor cells ex vivo and in an in vivo mouse model

Sharmineh Mansoori, Kristin Blom, Claes Andersson, Mårten Fryknäs, Rolf Larsson, Peter Nygren
Article Number: 9
Published online on: 31 October 2025

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Correction Open Access

[Corrigendum] Gemcitabine combined with an engineered oncolytic vaccinia virus exhibits a synergistic suppressive effect on the tumor growth of pancreatic cancer

Wanyuan Chen, Weimin Fan, Guoqing Ru, Fang Huang, Xiaming Lu, Xin Zhang, Xiaozhou Mou, Shibing Wang
Article Number: 8
Published online on: 30 October 2025

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Article Open Access

CD44 knockdown and TGF‑β inhibition modulate cell proliferation and invasion in claudin‑low breast cancer cells

Ryoichi Matsunuma, Kazuo Kinoshita, Sae Imada, Shoko Sato, Ryosuke Hayami, Michiko Tsuneizumi
Article Number: 7
Published online on: 30 October 2025

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Retraction Open Access

[Retracted] MicroRNA‑302a targets GAB2 to suppress cell proliferation, migration and invasion of glioma

Jiuhong Ma, Jia Yu, Jingmei Liu, Xing Yang, Miao Lou, Jinghui Liu, Fuqiang Feng, Peigang Ji, Liang Wang
Article Number: 6
Published online on: 27 October 2025

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Article Open Access

LRRC59 inhibits perk pathway‑induced apoptosis and promotes cell proliferation, migration and invasion in colorectal cancer cells

Xingdong Hou, Yuting Wang, Yuzhuo Chen, Peiyan Zhong, Guangzhi Wang, Baicheng Li, Bowei Lu, Hanyu Jiang, Shili Ning
Article Number: 5
Published online on: 23 October 2025

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Article Open Access

Comparative analysis of the efficacy and safety of antibody‑drug conjugates, radionuclide‑drug conjugates and their combination targeting claudin 18.2 in gastric cancer treatment

Huan Du, Xiao-Fei Hao, Bin-Wei Lin, Yu Zhang, Luo Rui, Jing Wang, Ming-Ming Tang, De-Cai Wang, Yi-Han Zhu, Jie Li, Tang-Zhi Dai, Yuchuan Yang, Xia Yang, Xiaobo Du
Article Number: 4
Published online on: 22 October 2025

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Expression of Concern Open Access

[Expression of Concern] CDKN3 is an independent prognostic factor and promotes ovarian carcinoma cell proliferation in ovarian cancer

Tianren Li, Hui Xue, Yi Guo, Kejun Guo
Article Number: 3
Published online on: 16 October 2025

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Review Open Access

Platelet‑circulating tumor cell crosstalk: A pivotal target in cancer diagnosis and therapy (Review)

Lifang Zhang, Ye Yuan, Yan Deng, Lin Wang, Fenghua Chen
Article Number: 2
Published online on: 15 October 2025

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Expression of Concern Open Access

[Expression of Concern] Knockdown of Bmi1 inhibits the stemness properties and tumorigenicity of human bladder cancer stem cell‑like side population cells

Dingjun Zhu, Xuesi Wan, Hai Huang, Xu Chen, Wu Liang, Fengjin Zhao, Tianxin Lin, Jinli Han, Wenlian Xie
Article Number: 1
Published online on: 14 October 2025

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Journal Cover
February-2026 Volume 55 Issue 2

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review Open Access

Alternative splicing in cancer drug resistance: Mechanisms and therapeutic prospects (Review)

Wenpu Zhu, Zikun Wu, Chai Luv, Banghe Bao, Weijie Zhao, Guanglong Chen, Hang Yang, Huihan Ai, Faqiang Liu, Zhi Li
Article Number: 31
Published online on: 05 December 2025

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Article Open Access

Inhibition of primary ciliogenesis enhances efficacy of EGFR‑TKIs against non‑small cell lung cancer cells

Liangliang Jin, Li Wei, Junrui Hua, Rong Zhang, Jiaxin Chen, Jinpeng He, Yanli Yang
Article Number: 30
Published online on: 04 December 2025

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Review

Beyond eradication: Therapeutic reprogramming strategies for cancer normalization (Review)

Aliasgar Shahiwala
Article Number: 29
Published online on: 04 December 2025

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Article Open Access

Saikosaponin D overcomes gemcitabine resistance in pancreatic cancer via AKT/mTOR pathway inhibition and synergistic induction of apoptosis and autophagy

Rui Zheng, Yusi Liu, Sen Zhou, Guimei Liu, Xiaobin Liu, Yiyuan Yang, Yufu Zhang
Article Number: 28
Published online on: 04 December 2025

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Retraction Open Access

[Retracted] Downregulation of Bmi‑1 is associated with suppressed tumorigenesis and induced apoptosis in CD44+ nasopharyngeal carcinoma cancer stem‑like cells

Xinhua Xu, Yang Liu, Jin Su, Daojun Li, Juan Hu, Qiao Huang, Mingqian Lu, Xiaoyan Liu, Jinghua Ren, Weihong Chen, Lidan Sun
Article Number: 27
Published online on: 04 December 2025

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Article Open Access

Prognostic significance of fibroblast senescence and senescence-associated secretory phenotype factor expression in the tumor microenvironment of pancreatic ductal adenocarcinoma

Yuto Kitano, Tomoharu Miyashita, Takeo Shimasaki, Isamu Makino, Yoshio Endo, Yasuhiko Yamamoto, Noriyuki Inaki, Shintaro Yagi
Article Number: 26
Published online on: 03 December 2025

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Retraction Open Access

[Retracted] Sp1‑CD147 positive feedback loop promotes the invasion ability of ovarian cancer

Jing Zhao, Wei Ye, Juan Wu, Lijuan Liu, Lina Yang, Lu Gao, Biliang Chen, Fanglin Zhang, Hong Yang, Yu Li
Article Number: 25
Published online on: 25 November 2025

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