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Oncology Reports
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Print ISSN: 1021-335X Online ISSN: 1791-2431
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December 2006 Volume 16 Issue 6

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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

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December 2006 Volume 16 Issue 6

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Article

Potential predictors of survival after surgery for colorectal cancer patients with synchronous unresectable liver metastases

  • Authors:
    • Tsukasa Hotta
    • Katsunari Takifuji
    • Kazuhisa Uchiyama
    • Shozo Yokoyama
    • Kenji Matsuda
    • Takashi Higashiguchi
    • Toshiji Tominaga
    • Yoshimasa Oku
    • Toru Nasu
    • Hiroki Yamaue

  • View Affiliations / Copyright

    Affiliations: Second Department of Surgery, Wakayama Medical University, School of Medicine, Wakayama, Japan
  • Pages: 1369-1374
    |
    Published online on: December 1, 2006
       https://doi.org/10.3892/or.16.6.1369
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Abstract

Liver resection has been recognized as the best treatment for patients with colorectal liver metastases, but as a curative resection for multiple and bilobar colorectal liver metastases (MBCLM) it is definitely less effective. We clarify predictors of survival for unresectable MBCLM. Potential predictors of overall survival, and the correlation between tumor marker and survival were evaluated for patients with synchronous unresectable MBCLM, including 6 rectal and 17 colon cancers. In univariate analysis, survival in patients with the following parameters were longer than those without them: number of liver metastases (≤10), without lung metastasis and peritoneal invasion, and with a <1.0 ratio of postoperative CEA/preoperative CEA. In multivariate analysis, the numbers of liver metastases (>10) and a >1.0 ratio of postoperative CEA/preoperative CEA were factors of poor prognosis, and patients with two such factors had an even worse prognosis. There was a tendency for correlation between the ratio of postoperative CEA/pre-operative CEA and survival (R=−0.492, P=0.053; y=17.388-3.733x). Thus, we clarified some of the predictors of survival for MBCLM, and the usefulness of serum CEA.

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Copy and paste a formatted citation
Spandidos Publications style
Hotta T, Takifuji K, Uchiyama K, Yokoyama S, Matsuda K, Higashiguchi T, Tominaga T, Oku Y, Nasu T, Yamaue H, Yamaue H, et al: Potential predictors of survival after surgery for colorectal cancer patients with synchronous unresectable liver metastases. Oncol Rep 16: 1369-1374, 2006.
APA
Hotta, T., Takifuji, K., Uchiyama, K., Yokoyama, S., Matsuda, K., Higashiguchi, T. ... Yamaue, H. (2006). Potential predictors of survival after surgery for colorectal cancer patients with synchronous unresectable liver metastases. Oncology Reports, 16, 1369-1374. https://doi.org/10.3892/or.16.6.1369
MLA
Hotta, T., Takifuji, K., Uchiyama, K., Yokoyama, S., Matsuda, K., Higashiguchi, T., Tominaga, T., Oku, Y., Nasu, T., Yamaue, H."Potential predictors of survival after surgery for colorectal cancer patients with synchronous unresectable liver metastases". Oncology Reports 16.6 (2006): 1369-1374.
Chicago
Hotta, T., Takifuji, K., Uchiyama, K., Yokoyama, S., Matsuda, K., Higashiguchi, T., Tominaga, T., Oku, Y., Nasu, T., Yamaue, H."Potential predictors of survival after surgery for colorectal cancer patients with synchronous unresectable liver metastases". Oncology Reports 16, no. 6 (2006): 1369-1374. https://doi.org/10.3892/or.16.6.1369
Copy and paste a formatted citation
x
Spandidos Publications style
Hotta T, Takifuji K, Uchiyama K, Yokoyama S, Matsuda K, Higashiguchi T, Tominaga T, Oku Y, Nasu T, Yamaue H, Yamaue H, et al: Potential predictors of survival after surgery for colorectal cancer patients with synchronous unresectable liver metastases. Oncol Rep 16: 1369-1374, 2006.
APA
Hotta, T., Takifuji, K., Uchiyama, K., Yokoyama, S., Matsuda, K., Higashiguchi, T. ... Yamaue, H. (2006). Potential predictors of survival after surgery for colorectal cancer patients with synchronous unresectable liver metastases. Oncology Reports, 16, 1369-1374. https://doi.org/10.3892/or.16.6.1369
MLA
Hotta, T., Takifuji, K., Uchiyama, K., Yokoyama, S., Matsuda, K., Higashiguchi, T., Tominaga, T., Oku, Y., Nasu, T., Yamaue, H."Potential predictors of survival after surgery for colorectal cancer patients with synchronous unresectable liver metastases". Oncology Reports 16.6 (2006): 1369-1374.
Chicago
Hotta, T., Takifuji, K., Uchiyama, K., Yokoyama, S., Matsuda, K., Higashiguchi, T., Tominaga, T., Oku, Y., Nasu, T., Yamaue, H."Potential predictors of survival after surgery for colorectal cancer patients with synchronous unresectable liver metastases". Oncology Reports 16, no. 6 (2006): 1369-1374. https://doi.org/10.3892/or.16.6.1369
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