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Oncology Reports
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Print ISSN: 1021-335X Online ISSN: 1791-2431
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June 2007 Volume 17 Issue 6

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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Article

Expression levels of heat shock protein 20 decrease in parallel with tumor progression in patients with hepatocellular carcinoma

  • Authors:
    • Takahiro Noda
    • Takashi Kumada
    • Shinji Takai
    • Rie Matsushima-Nishiwaki
    • Naoki Yoshimi
    • Eisuke Yasuda
    • Kanefusa Kato
    • Hidenori Toyoda
    • Yuji Kaneoka
    • Akihiro Yamaguchi
    • Osamu Kozawa

  • View Affiliations / Copyright

    Affiliations: Department of Pharmacology, Gifu University Graduate School of Medicine, Gifu 501-1194, Japan
  • Pages: 1309-1314
    |
    Published online on: June 1, 2007
       https://doi.org/10.3892/or.17.6.1309
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Abstract

Heat shock protein (HSP) 20, a low-molecular-weight HSP, is constitutively expressed in various tissues, such as smooth muscle, skeletal muscle, and liver. However, the characteristics and function of HSP20 have not been precisely understood. In the present study, we investigated correlations of expression levels of HSP20 in hepatocellular carcinoma (HCC) tissues and the surrounding tissues with clinical and pathologic characteristics in 53 resected HCC specimens. Although HSP20 was detected in all 53 HCC tissues, the expression levels were reduced compared with those in the adjacent non-tumor tissues. The expression levels of HSP20 were inversely correlated with tumor stage by TNM classification (p<0.01), presence of microvascular invasion (p<0.05), and tumor size (p<0.05). Our findings strongly suggest that HSP20 may play a role against the progression of human HCC.

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Copy and paste a formatted citation
Spandidos Publications style
Noda T, Kumada T, Takai S, Matsushima-Nishiwaki R, Yoshimi N, Yasuda E, Kato K, Toyoda H, Kaneoka Y, Yamaguchi A, Yamaguchi A, et al: Expression levels of heat shock protein 20 decrease in parallel with tumor progression in patients with hepatocellular carcinoma. Oncol Rep 17: 1309-1314, 2007.
APA
Noda, T., Kumada, T., Takai, S., Matsushima-Nishiwaki, R., Yoshimi, N., Yasuda, E. ... Kozawa, O. (2007). Expression levels of heat shock protein 20 decrease in parallel with tumor progression in patients with hepatocellular carcinoma. Oncology Reports, 17, 1309-1314. https://doi.org/10.3892/or.17.6.1309
MLA
Noda, T., Kumada, T., Takai, S., Matsushima-Nishiwaki, R., Yoshimi, N., Yasuda, E., Kato, K., Toyoda, H., Kaneoka, Y., Yamaguchi, A., Kozawa, O."Expression levels of heat shock protein 20 decrease in parallel with tumor progression in patients with hepatocellular carcinoma". Oncology Reports 17.6 (2007): 1309-1314.
Chicago
Noda, T., Kumada, T., Takai, S., Matsushima-Nishiwaki, R., Yoshimi, N., Yasuda, E., Kato, K., Toyoda, H., Kaneoka, Y., Yamaguchi, A., Kozawa, O."Expression levels of heat shock protein 20 decrease in parallel with tumor progression in patients with hepatocellular carcinoma". Oncology Reports 17, no. 6 (2007): 1309-1314. https://doi.org/10.3892/or.17.6.1309
Copy and paste a formatted citation
x
Spandidos Publications style
Noda T, Kumada T, Takai S, Matsushima-Nishiwaki R, Yoshimi N, Yasuda E, Kato K, Toyoda H, Kaneoka Y, Yamaguchi A, Yamaguchi A, et al: Expression levels of heat shock protein 20 decrease in parallel with tumor progression in patients with hepatocellular carcinoma. Oncol Rep 17: 1309-1314, 2007.
APA
Noda, T., Kumada, T., Takai, S., Matsushima-Nishiwaki, R., Yoshimi, N., Yasuda, E. ... Kozawa, O. (2007). Expression levels of heat shock protein 20 decrease in parallel with tumor progression in patients with hepatocellular carcinoma. Oncology Reports, 17, 1309-1314. https://doi.org/10.3892/or.17.6.1309
MLA
Noda, T., Kumada, T., Takai, S., Matsushima-Nishiwaki, R., Yoshimi, N., Yasuda, E., Kato, K., Toyoda, H., Kaneoka, Y., Yamaguchi, A., Kozawa, O."Expression levels of heat shock protein 20 decrease in parallel with tumor progression in patients with hepatocellular carcinoma". Oncology Reports 17.6 (2007): 1309-1314.
Chicago
Noda, T., Kumada, T., Takai, S., Matsushima-Nishiwaki, R., Yoshimi, N., Yasuda, E., Kato, K., Toyoda, H., Kaneoka, Y., Yamaguchi, A., Kozawa, O."Expression levels of heat shock protein 20 decrease in parallel with tumor progression in patients with hepatocellular carcinoma". Oncology Reports 17, no. 6 (2007): 1309-1314. https://doi.org/10.3892/or.17.6.1309
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