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Oncology Reports
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Print ISSN: 1021-335X Online ISSN: 1791-2431
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November 2007 Volume 18 Issue 5

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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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November 2007 Volume 18 Issue 5

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Article

Expression of AITR and AITR ligand in breast cancer patients

  • Authors:
    • Yon Seon Kim
    • Hyo Won Jung
    • Ji Choi
    • Byung Sae Kwon
    • Soo-Youn Ham
    • Ae Kyung Jung
    • Byung Kyun Ko

  • View Affiliations / Copyright

    Affiliations: Department of Surgery, Ulsan University Hospital, Ulsan University College of Medicine, Ulsan 682-714, Korea
  • Pages: 1189-1194
    |
    Published online on: November 1, 2007
       https://doi.org/10.3892/or.18.5.1189
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Abstract

Human activation-inducible TNF receptor (AITR) is a new member of the tumor necrosis factor family and expressed on peripheral blood mononuclear cells (PBMC) and leukocytes. Its ligand (AITRL) is expressed in endothelial cells. This study aimed to evaluate the presence and role of AITR and AITRL in patients with breast cancer. Expression of AITR and AITRL on PBMC and breast cancer cells was determined by flow cytometry, RT-PCR and fluorescence microscopy. Soluble (s) AITR and sAITRL were detected in serum of breast cancer patients by ELISA. AITR and AITRL were constitutively expressed in T cells, B cells, monocytes and monocyte-derived dendritic cells of breast cancer patients. AITRL was overexpressed in breast cancer cells. The levels of sAITRL were significantly increased in serum of breast cancer patients compared with the healthy control. This study suggests that AITR and AITRL may play an important role in tumor growth and survival in breast cancer.

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Copy and paste a formatted citation
Spandidos Publications style
Kim YS, Jung HW, Choi J, Kwon BS, Ham S, Jung AK and Ko BK: Expression of AITR and AITR ligand in breast cancer patients. Oncol Rep 18: 1189-1194, 2007.
APA
Kim, Y.S., Jung, H.W., Choi, J., Kwon, B.S., Ham, S., Jung, A.K., & Ko, B.K. (2007). Expression of AITR and AITR ligand in breast cancer patients. Oncology Reports, 18, 1189-1194. https://doi.org/10.3892/or.18.5.1189
MLA
Kim, Y. S., Jung, H. W., Choi, J., Kwon, B. S., Ham, S., Jung, A. K., Ko, B. K."Expression of AITR and AITR ligand in breast cancer patients". Oncology Reports 18.5 (2007): 1189-1194.
Chicago
Kim, Y. S., Jung, H. W., Choi, J., Kwon, B. S., Ham, S., Jung, A. K., Ko, B. K."Expression of AITR and AITR ligand in breast cancer patients". Oncology Reports 18, no. 5 (2007): 1189-1194. https://doi.org/10.3892/or.18.5.1189
Copy and paste a formatted citation
x
Spandidos Publications style
Kim YS, Jung HW, Choi J, Kwon BS, Ham S, Jung AK and Ko BK: Expression of AITR and AITR ligand in breast cancer patients. Oncol Rep 18: 1189-1194, 2007.
APA
Kim, Y.S., Jung, H.W., Choi, J., Kwon, B.S., Ham, S., Jung, A.K., & Ko, B.K. (2007). Expression of AITR and AITR ligand in breast cancer patients. Oncology Reports, 18, 1189-1194. https://doi.org/10.3892/or.18.5.1189
MLA
Kim, Y. S., Jung, H. W., Choi, J., Kwon, B. S., Ham, S., Jung, A. K., Ko, B. K."Expression of AITR and AITR ligand in breast cancer patients". Oncology Reports 18.5 (2007): 1189-1194.
Chicago
Kim, Y. S., Jung, H. W., Choi, J., Kwon, B. S., Ham, S., Jung, A. K., Ko, B. K."Expression of AITR and AITR ligand in breast cancer patients". Oncology Reports 18, no. 5 (2007): 1189-1194. https://doi.org/10.3892/or.18.5.1189
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