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Oncology Reports
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Print ISSN: 1021-335X Online ISSN: 1791-2431
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September 1995 Volume 2 Issue 5

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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

Journal Cover
September 1995 Volume 2 Issue 5

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Article

ANTIPROLIFERATIVE EFFECTS OF GARLIC CONSTITUENTS IN CULTURED HUMAN BREAST-CANCER CELLS

  • Authors:
    • G LI
    • CH QIAO
    • RI LIN
    • J PINTO
    • MP OSBORNE
    • RK TIWARI

  • View Affiliations / Copyright

    Affiliations: CORNELL UNIV,COLL MED,STRANG CORNELL CANC RES LAB,NEW YORK,NY 10021. MEM SLOAN KETTERING CANC CTR,NEW YORK,NY 10021. NUTR INT,IRVINE,CA.
  • Pages: 787-791
    |
    Published online on: September 1, 1995
       https://doi.org/10.3892/or.2.5.787
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Abstract

The medicinal uses of garlic (Allium sativum) and its constituents have been known for centuries, though its mode of action is still undetermined. Several epidemiological and laboratory studies indicate a potential anti-carcinogenic effect of garlic and some of its constituents. In this study we investigated the effect of aged garlic extract (AGE) and two of its components, S-allylcysteine (SAC), and S-allyl-mercaptocysteine (SAMC) on human breast cancer cells, MCF-7 and MCF-7(ras). Transfection of v-H-ras in MCF-7 cells gives rise to a highly aggressive subset of cells that is estrogen independent and has a five fold greater colony forming efficiency in soft agar than the parent cell line. The modulatory effect of AGE, SAC and SAMC on growth and glutathione cycle was examined in the two cell lines. We noted an anti-proliferative response to SAC and SAMC on both anchorage dependent and independent conditions and an alteration in glutathione level without significant concurrent changes in the glutathione metabolizing enzymes.

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Copy and paste a formatted citation
Spandidos Publications style
LI G, QIAO C, LIN R, PINTO J, OSBORNE M and TIWARI R: ANTIPROLIFERATIVE EFFECTS OF GARLIC CONSTITUENTS IN CULTURED HUMAN BREAST-CANCER CELLS. Oncol Rep 2: 787-791, 1995.
APA
LI, G., QIAO, C., LIN, R., PINTO, J., OSBORNE, M., & TIWARI, R. (1995). ANTIPROLIFERATIVE EFFECTS OF GARLIC CONSTITUENTS IN CULTURED HUMAN BREAST-CANCER CELLS. Oncology Reports, 2, 787-791. https://doi.org/10.3892/or.2.5.787
MLA
LI, G., QIAO, C., LIN, R., PINTO, J., OSBORNE, M., TIWARI, R."ANTIPROLIFERATIVE EFFECTS OF GARLIC CONSTITUENTS IN CULTURED HUMAN BREAST-CANCER CELLS". Oncology Reports 2.5 (1995): 787-791.
Chicago
LI, G., QIAO, C., LIN, R., PINTO, J., OSBORNE, M., TIWARI, R."ANTIPROLIFERATIVE EFFECTS OF GARLIC CONSTITUENTS IN CULTURED HUMAN BREAST-CANCER CELLS". Oncology Reports 2, no. 5 (1995): 787-791. https://doi.org/10.3892/or.2.5.787
Copy and paste a formatted citation
x
Spandidos Publications style
LI G, QIAO C, LIN R, PINTO J, OSBORNE M and TIWARI R: ANTIPROLIFERATIVE EFFECTS OF GARLIC CONSTITUENTS IN CULTURED HUMAN BREAST-CANCER CELLS. Oncol Rep 2: 787-791, 1995.
APA
LI, G., QIAO, C., LIN, R., PINTO, J., OSBORNE, M., & TIWARI, R. (1995). ANTIPROLIFERATIVE EFFECTS OF GARLIC CONSTITUENTS IN CULTURED HUMAN BREAST-CANCER CELLS. Oncology Reports, 2, 787-791. https://doi.org/10.3892/or.2.5.787
MLA
LI, G., QIAO, C., LIN, R., PINTO, J., OSBORNE, M., TIWARI, R."ANTIPROLIFERATIVE EFFECTS OF GARLIC CONSTITUENTS IN CULTURED HUMAN BREAST-CANCER CELLS". Oncology Reports 2.5 (1995): 787-791.
Chicago
LI, G., QIAO, C., LIN, R., PINTO, J., OSBORNE, M., TIWARI, R."ANTIPROLIFERATIVE EFFECTS OF GARLIC CONSTITUENTS IN CULTURED HUMAN BREAST-CANCER CELLS". Oncology Reports 2, no. 5 (1995): 787-791. https://doi.org/10.3892/or.2.5.787
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