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HUMAN PAPILLOMAVIRUS TYPE-16 DNA INTEGRATION IN NUCLEAR MATRIX AND CHROMOSOME SCAFFOLD ASSOCIATED DNA IN A CERVICAL-CARCINOMA CELL-LINE

  • Authors:
    • YF YAM
    • EC CHEW
    • L YANG
    • SB CHENGCHEW
    • MX DING

  • View Affiliations

  • Published online on: November 1, 1995     https://doi.org/10.3892/or.2.6.1093
  • Pages: 1093-1096
Metrics: Total Views: 0 (Spandidos Publications: | PMC Statistics: )
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Abstract

MARs (matrix attachment region) and SARs (scaffold attachment region) are fragments of DNA that associated with nuclear matrix and chromosome scaffold even after extensive removal of most of the nuclear proteins and chromatin. The present study showed the association of human papillomavirus type 16 DNA with these fragments by polymerase chain reaction in a cervical carcinoma cell line, CC3/CUHK3. This finding proposed an alternative evidence for the elevated transcription rate of the viral genome in transformed cells as nuclear matrix has been proposed to be sites of DNA replication and transcription.

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November 1995
Volume 2 Issue 6

Print ISSN: 1021-335X
Online ISSN:1791-2431

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  • Journal Metrics
  • Impact Factor: 4.2
  • Ranked Oncology
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  • CiteScore: 8.4
  • CiteScore Rank: Q1: #68/366 Oncology
  • Source Normalized Impact per Paper (SNIP): 0.786
  • SCImago Journal Rank (SJR): 0.812
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Spandidos Publications style
YAM Y, CHEW E, YANG L, CHENGCHEW S and DING M: HUMAN PAPILLOMAVIRUS TYPE-16 DNA INTEGRATION IN NUCLEAR MATRIX AND CHROMOSOME SCAFFOLD ASSOCIATED DNA IN A CERVICAL-CARCINOMA CELL-LINE. Oncol Rep 2: 1093-1096, 1995
APA
YAM, Y., CHEW, E., YANG, L., CHENGCHEW, S., & DING, M. (1995). HUMAN PAPILLOMAVIRUS TYPE-16 DNA INTEGRATION IN NUCLEAR MATRIX AND CHROMOSOME SCAFFOLD ASSOCIATED DNA IN A CERVICAL-CARCINOMA CELL-LINE. Oncology Reports, 2, 1093-1096. https://doi.org/10.3892/or.2.6.1093
MLA
YAM, Y., CHEW, E., YANG, L., CHENGCHEW, S., DING, M."HUMAN PAPILLOMAVIRUS TYPE-16 DNA INTEGRATION IN NUCLEAR MATRIX AND CHROMOSOME SCAFFOLD ASSOCIATED DNA IN A CERVICAL-CARCINOMA CELL-LINE". Oncology Reports 2.6 (1995): 1093-1096.
Chicago
YAM, Y., CHEW, E., YANG, L., CHENGCHEW, S., DING, M."HUMAN PAPILLOMAVIRUS TYPE-16 DNA INTEGRATION IN NUCLEAR MATRIX AND CHROMOSOME SCAFFOLD ASSOCIATED DNA IN A CERVICAL-CARCINOMA CELL-LINE". Oncology Reports 2, no. 6 (1995): 1093-1096. https://doi.org/10.3892/or.2.6.1093