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Oncology Reports
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Print ISSN: 1021-335X Online ISSN: 1791-2431
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February 2011 Volume 25 Issue 2

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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Article

IFITM6 expression is increased in macrophages of tumor-bearing mice

  • Authors:
    • Jeong Hye Han
    • Sunyi Lee
    • Yun Sun Park
    • Jeong Su Park
    • Kun-Yong Kim
    • Jong Seok Lim
    • Ki Sook Oh
    • Young Yang

  • View Affiliations / Copyright

    Affiliations: Department of Biological Science, Sookmyung Women's University, Seoul 140-742, Republic of Korea, Department of Life Science, Sookmyung Women's University, Seoul 140-742, Republic of Korea
  • Pages: 531-536
    |
    Published online on: December 10, 2010
       https://doi.org/10.3892/or.2010.1092
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Abstract

The family of interferon-induced transmembrane protein (IFITM) genes consists of IFITM1, 2, 3, 5, and 6. They encode cell surface proteins that modulate cell-cell adhesion and cell differentiation. In a previous study, we showed that IFITM1 is involved in the immune escape and metastasis of gastric cancer cells. In this study, we determined the difference in expression of IFITM family genes in tumor-bearing mice. IFITM1 and 6 were found to be significantly increased. IFITM6 gene expression was increased only in the spleen of tumor-bearing mice but not in the bone marrow, lymph node, or thymus. IFITM6 expression was induced in various macrophages, including splenic, thioglycollate-elicited, and bone marrow-derived macrophages, but not in T cells. Lipopolysaccharides (LPS) also increased IFITM6 expression 24 h after administration, and Toll-like receptor 1, 2, 3, 4, and 9 agonists stimulated IFITM6 expression. These findings imply that the increase in IFITM6 expression may be involved in macrophage functions of tumor-bearing mice.

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Copy and paste a formatted citation
Spandidos Publications style
Han JH, Lee S, Park YS, Park JS, Kim K, Lim JS, Oh KS and Yang Y: IFITM6 expression is increased in macrophages of tumor-bearing mice. Oncol Rep 25: 531-536, 2011.
APA
Han, J.H., Lee, S., Park, Y.S., Park, J.S., Kim, K., Lim, J.S. ... Yang, Y. (2011). IFITM6 expression is increased in macrophages of tumor-bearing mice. Oncology Reports, 25, 531-536. https://doi.org/10.3892/or.2010.1092
MLA
Han, J. H., Lee, S., Park, Y. S., Park, J. S., Kim, K., Lim, J. S., Oh, K. S., Yang, Y."IFITM6 expression is increased in macrophages of tumor-bearing mice". Oncology Reports 25.2 (2011): 531-536.
Chicago
Han, J. H., Lee, S., Park, Y. S., Park, J. S., Kim, K., Lim, J. S., Oh, K. S., Yang, Y."IFITM6 expression is increased in macrophages of tumor-bearing mice". Oncology Reports 25, no. 2 (2011): 531-536. https://doi.org/10.3892/or.2010.1092
Copy and paste a formatted citation
x
Spandidos Publications style
Han JH, Lee S, Park YS, Park JS, Kim K, Lim JS, Oh KS and Yang Y: IFITM6 expression is increased in macrophages of tumor-bearing mice. Oncol Rep 25: 531-536, 2011.
APA
Han, J.H., Lee, S., Park, Y.S., Park, J.S., Kim, K., Lim, J.S. ... Yang, Y. (2011). IFITM6 expression is increased in macrophages of tumor-bearing mice. Oncology Reports, 25, 531-536. https://doi.org/10.3892/or.2010.1092
MLA
Han, J. H., Lee, S., Park, Y. S., Park, J. S., Kim, K., Lim, J. S., Oh, K. S., Yang, Y."IFITM6 expression is increased in macrophages of tumor-bearing mice". Oncology Reports 25.2 (2011): 531-536.
Chicago
Han, J. H., Lee, S., Park, Y. S., Park, J. S., Kim, K., Lim, J. S., Oh, K. S., Yang, Y."IFITM6 expression is increased in macrophages of tumor-bearing mice". Oncology Reports 25, no. 2 (2011): 531-536. https://doi.org/10.3892/or.2010.1092
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