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Print ISSN: 1021-335X Online ISSN: 1791-2431
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
February 2011 Volume 25 Issue 2

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Article

Plasma proteome predicts chemotherapy response in osteosarcoma patients

Yiting Li, Tu Anh Dang, Jianhe Shen, John Hicks, Murali Chintagumpala, Ching C. Lau, Tsz-Kwong Man
Pages: 303-314
Published online on: 15 December 2010

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Article

Fructose transporter Glut5 expression in clear renal cell carcinoma

V. Medina Villaamil, G. Aparicio Gallego, L. Valbuena Rubira, R. García Campelo, M. Valladares-Ayerbes, E. Grande Pulido, M. Victoria Bolós, I. Santamarina Caínzos, L. M. Antón Aparicio
Pages: 315-323
Published online on: 10 December 2010

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Article

A novel recombinant immuno-tBid with a furin site effectively suppresses the growth of HER2-positive osteosarcoma cells in vitro

Le-Qun Shan, Sai Ma, Xiu-Chun Qiu, Tao Wang, Shi-Bin Yu, Bao-An Ma, Yong Zhou, Qing-Yu Fan, An-Gang Yang
Pages: 325-331
Published online on: 07 December 2010

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Article Open Access

ATP-binding cassette transporters in primary central nervous system lymphoma: Decreased expression of MDR1 P-glycoprotein and breast cancer resistance protein in tumor capillary endothelial cells

Seiji Sakata, Masachika Fujiwara, Kouki Ohtsuka, Hiroshi Kamma, Motoo Nagane, Atsuhiko Sakamoto, Yasunori Fujioka
Pages: 333-339
Published online on: 13 December 2010

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Article

Rapid decrease of intracellular pH associated with inhibition of Na+/H+ exchanger precedes apoptotic events in the MNK45 and MNK74 gastric cancer cell lines treated with 2-aminophenoxazine-3-one

Hiroyuki Nagata, Xiao-Fang Che, Keisuke Miyazawa, Akio Tomoda, Masato Konishi, Hideyuki Ubukata, Takafumi Tabuchi
Pages: 341-346
Published online on: 08 December 2010

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Article

Camptothecin induces DNA strand breaks and is cytotoxic in stimulated normal lymphocytes

Takahiro Yamauchi, Akira Yoshida, Takanori Ueda
Pages: 347-352
Published online on: 10 December 2010

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Article

Clinical and prognostic significance of lost or decreased PDCD5 expression in human epithelial ovarian carcinomas

Xia Zhang, Xiaoyan Wang, Xingguo Song, Zengtao Wei, Chengjun Zhou, Faliang Zhu, Qun Wang, Chunhong Ma, Liling Zhang
Pages: 353-358
Published online on: 13 December 2010

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Article

Differential expression and function of the caveolin-1 gene in non-small cell lung carcinoma

Hong Lei Chen, Li Fang Fan, Jun Gao, Jing Ping Ouyang, Yu Xia Zhang
Pages: 359-366
Published online on: 10 December 2010

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Article

WNT5A expression is regulated by the status of its promoter methylation in leukaemia and can inhibit leukemic cell malignant proliferation

Gang Deng, Zhao Quan Li, Chen Zhao, Yuan Yuan, Chang Chun Niu, Chen Zhao, Jing Pan, Wei Ke Si
Pages: 367-376
Published online on: 14 December 2010

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Article

Association of the transforming growth factor ß1 promoter polymorphism, C-509T, with smoking status and survival in advanced non-small cell lung cancer

Yosuke Togashi, Katsuhiro Masago, Shiro Fujita, Young Hak Kim, Yuichi Sakamori, Yukimasa Hatachi, Akiko Fukuhara, Hiroki Nagai, Tadashi Mio, Michiaki Mishima
Pages: 377-382
Published online on: 10 December 2010

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Article

NF-κB participates in chemokine receptor 7-mediated cell survival in metastatic squamous cell carcinoma of the head and neck

Fa-Yu Liu, Zhen-Jin Zhao, Peng Li, Xue Ding, Nan Guo, Liang-Liang Yang, Zhi-Hong Zong, Chang-Fu Sun
Pages: 383-391
Published online on: 09 December 2010

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Article

Histone deacetylase inhibitors control the transcription and alternative splicing of prohibitin in thyroid tumor cells

Cinzia Puppin, Nadia Passon, Alessandra Franzoni, Diego Russo, Giuseppe Damante
Pages: 393-397
Published online on: 07 December 2010

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Article

Transcriptional changes induced by epigenetic therapy with hydralazine and magnesium valproate in cervical carcinoma

Erick De la Cruz-Hernández, Carlos Perez-Plasencia, Enrique Pérez-Cardenas, Aurora Gonzalez-Fierro, Catalina Trejo-Becerril, Alma Chávez-Blanco, Lucia Taja-Chayeb, Silvia Vidal, Olga Gutiérrez, Guadalupe I. Dominguez, Jaenai E. Trujillo, Alfonso Duenas-González
Pages: 399-407
Published online on: 08 December 2010

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Article

Knockdown of the Bmi-1 oncogene inhibits cell proliferation and induces cell apoptosis and is involved in the decrease of Akt phosphorylation in the human breast carcinoma cell line MCF-7

Zhengshun Xu, Hongtao Liu, Xinquan Lv, Yuqiong Liu, Shenglei Li, Huixiang Li
Pages: 409-418
Published online on: 07 December 2010

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Article

Death receptor 5-mediated TNFR family signaling pathways modulate γ-humulene-induced apoptosis in human colorectal cancer HT29 cells

Yu-Hsuan Lan, Yang-Chang Wu, Kai-Wei Wu, Jing-Gung Chung, Chi-Cheng Lu, Yuan-Liang Chen, Tian-Shung Wu, Jai-Sing Yang
Pages: 419-424
Published online on: 08 December 2010

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Article

Inhibition of CD147 gene expression via RNA interference reduces tumor cell invasion, tumorigenicity and increases chemosensitivity to cisplatin in laryngeal carcinoma Hep2 cells

Chan Zhu, Yuqin Pan, Bangshun He, Bo Wang, Yongfei Xu, Lili Qu, Qian Bao, Fuliang Tian, Shukui Wang
Pages: 425-432
Published online on: 09 December 2010

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Article

Categorical meta-analysis of Osteopontin as a clinical cancer marker

Georg F. Weber, G. Scott Lett, Ned C. Haubein
Pages: 433-441
Published online on: 13 December 2010

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Article

Methyl-CpG binding protein MBD2 is implicated in methylation-mediated suppression of miR-373 in hilar cholangiocarcinoma

Yongjun Chen, Wei Gao, Jian Luo, Rui Tian, Huawen Sun, Shengquan Zou
Pages: 443-451
Published online on: 09 December 2010

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Article

Genetic pathways of multiple esophageal squamous cell carcinomas

Takayasu Kuwabara, Toru Hiyama, Shinji Tanaka, Masaharu Yoshihara, Koji Arihiro, Kazuaki Chayama
Pages: 453-459
Published online on: 14 December 2010

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Article

Cisplatin sensitizes human hepatocellular carcinoma cells, but not hepatocytes and mesenchymal stem cells, to TRAIL within a therapeutic window partially depending on the upregulation of DR5

Bo Zhang, Hong Shan, Dan Li, Zheng-Ran Li, Kang-Shun Zhu, Zai-Bo Jiang, Ming-Sheng Huang
Pages: 461-468
Published online on: 08 December 2010

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Article

Identification of HLA-A*0201/-A*2402-restricted CTL epitope-peptides derived from a novel cancer/testis antigen, MCAK, and induction of a specific antitumor immune response

Megumi Kawamoto, Fumiaki Tanaka, Koshi Mimori, Hiroshi Inoue, Yukio Kamohara, Masaki Mori
Pages: 469-476
Published online on: 10 December 2010

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Article

The molecular contribution of TNF-α in the link between obesity and breast cancer

Michael Weichhaus, Iain Broom, Giovanna Bermano
Pages: 477-483
Published online on: 10 December 2010

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Article

Human papillomavirus and non-muscle invasive urothelial bladder cancer: Potential relationship from a pilot study

Tommaso Cai, Sandra Mazzoli, Francesca Meacci, Gabriella Nesi, Pierangelo Geppetti, Gianni Malossini, Riccardo Bartoletti
Pages: 485-489
Published online on: 08 December 2010

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Article

3,3'-Diindolylmethane inhibits migration and invasion of human cancer cells through combined suppression of ERK and AKT pathways

Shilpi Rajoria, Robert Suriano, Yushan Lisa Wilson, Stimson P. Schantz, Augustine Moscatello, Jan Geliebter, Raj K. Tiwari
Pages: 491-497
Published online on: 07 December 2010

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Article

Evidence of molecular alterations in the tumour suppressor gene WWOX in benign and malignant bone related lesions of the jaws

Marina Gonçalves Diniz, Erica Rievrs Borges, Flavio Juliano Pimenta, Ana Carolina De Mesquita Netto, Luiz De Marco, Ricardo Santiago Gomez, Carolina Cavaliéri Gomes
Pages: 499-502
Published online on: 10 December 2010

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Article

Activation of PAR2 or/and TLR4 promotes SW620 cell proliferation and migration via phosphorylation of ERK1/2

Baocheng Zhou, Hong Zhou, Shucai Ling, Donglin Guo, Yihong Yan, Fang Zhou, Ying Wu
Pages: 503-511
Published online on: 07 December 2010

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Article

Methylation of BNIP3 and DAPK indicates lower response to chemotherapy and poor prognosis in gastric cancer

Hirofumi Sugita, Satoru Iida, Mikito Inokuchi, Keiji Kato, Megumi Ishiguro, Toshiaki Ishikawa, Yoko Takagi, Megumu Enjoji, Hiroyuki Yamada, Hiroyuki Uetake, Kazuyuki Kojima, Kenichi Sugihara
Pages: 513-518
Published online on: 08 December 2010

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Article

Screening of novel immunostimulatory CpG ODNs and their anti-leukemic effects as immunoadjuvants of tumor vaccines in murine acute lymphoblastic leukemia

Jin Wang, Wanggang Zhang, Aili He, Wanhong Zhao, Xingmei Cao
Pages: 519-529
Published online on: 10 December 2010

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Article

IFITM6 expression is increased in macrophages of tumor-bearing mice

Jeong Hye Han, Sunyi Lee, Yun Sun Park, Jeong Su Park, Kun-Yong Kim, Jong Seok Lim, Ki Sook Oh, Young Yang
Pages: 531-536
Published online on: 10 December 2010

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Article

MEKK1/MEKK4 are responsible for TRAIL-induced JNK/p38 phosphorylation

Bo K. Sun, Joo-Hang Kim, Hoan N. Nguyen, Seeun Oh, So Y. Kim, Soojin Choi, Hye J. Choi, Yong J. Lee, Jae J. Song
Pages: 537-544
Published online on: 07 December 2010

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Article

Anti-/pro-apoptotic effects of hesperetin against 7,12-dimetylbenz(a)anthracene-induced alteration in animals

Eun Jeong Choi, Gun-Hee Kim
Pages: 545-550
Published online on: 13 December 2010

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Article

Triptolide induces apoptosis in human adrenal cancer NCI-H295 cells through a mitochondrial-dependent pathway

Ping-Ping Wu, Kuo-Ching Liu, Wen-Wen Huang, Chia-Yu Ma, Hung Lin, Jai-Sing Yang, Jing-Gung Chung
Pages: 551-557
Published online on: 08 December 2010

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Article

Sox4 stimulates ß-catenin activity through induction of CK2

Ae-Kyung Lee, Sang-Gun Ahn, Jung-Hoon Yoon, Soo-A Kim
Pages: 559-565
Published online on: 09 December 2010

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Article

Anti-invasive activities of anthocyanins through modulation of tight junctions and suppression of matrix metalloproteinase activities in HCT-116 human colon carcinoma cells

Dong Yeok Shin, Jing Nan Lu, Gi-Young Kim, Jin Myung Jung, Ho Sung Kang, Won Sup Lee, Yung Hyun Choi
Pages: 567-572
Published online on: 13 December 2010

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Article

Cholesterol level determines viability and mitogenicity, but it does not affect sodium butyrate-dependent sensitization of Colo 205 cells to TNF-α-induced apoptosis

S. Orzechowska, B. Pajak, B. Gajkowska, A. Orzechowski
Pages: 573-582
Published online on: 08 December 2010

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Article

Quercetin induces FasL-related apoptosis, in part, through promotion of histone H3 acetylation in human leukemia HL-60 cells

Wei-Jiunn Lee, Yun-Ru Chen, Tsui-Hwa Tseng
Pages: 583-591
Published online on: 10 December 2010

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Journal Cover
May-2026 Volume 55 Issue 5

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Article Open Access

ZBTB7A promotes malignant phenotypes in ovarian cancer through transcriptional activation of CRLF1

Xiaobai Hao, Yu Chen
Article Number: 102
Published online on: 24 March 2026

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Article Open Access

MS4322 is a selective protein arginine methyltransferase 5 degrader with antitumor effects in cervical cancer cells

Rui Luo, Jingping Chen, Zhaojie Chen, Surong Wang, Tianfeng Liu, Yang Xu
Article Number: 101
Published online on: 24 March 2026

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Retraction Open Access

[Retracted] Roles of the SNHG7/microRNA‑9‑5p/DPP4 ceRNA network in the growth and 131I resistance of thyroid carcinoma cells through PI3K/Akt activation

Wanzhi Chen, Jichun Yu, Rong Xie, Tao Zhou, Chengfeng Xiong, Shuyong Zhang, Meijun Zhong
Article Number: 100
Published online on: 23 March 2026

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Article Open Access

Andrographis exerts antitumor effects and enhances 5‑FU efficacy via the alteration of ferroptosis‑related genes in esophageal squamous cell carcinoma

Kosuke Yoshimura, Tadanobu Shimura, Ruiya Ma, Yaxuan Huang, Takahito Kitajima, Shinji Yamashita, Yuki Sato, Koki Higashi, Mikio Kawamura, Hiromi Yasuda, Yuhki Koike, Yoshiki Okita, Shigeyuki Yoshiyama, Minako Kobayashi, Masaki Ohi, Hiroki Ohge, Shinya Takahashi, Ajay Goel, Yoshinaga Okugawa, Yuji Toiyama
Article Number: 99
Published online on: 20 March 2026

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Article Open Access

Sphingosine‑1‑phosphate receptor 1 enhances olfactory receptor 51E1‑mediated inhibition of proliferation via Src/JNK signaling in prostate cancer cells

Kiheon Kim, Jinwoo Lee, Chulwon Choi, Jungnam Bae, Hee-Jung Choi, Won-Ki Huh
Article Number: 98
Published online on: 19 March 2026

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Review Open Access

Mechanistic insights into the roles of astragalosides and Astragalus polysaccharides in gynecological and breast cancers (Review)

Ruixin Liu, Zhanyu Lin, Yuelin Li, Yuetong Ci, Zhengqi Guo, Zhenguo Xu
Article Number: 97
Published online on: 19 March 2026

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Retraction Open Access

[Retracted] Inhibition of tankyrase 1 in human gastric cancer cells enhances telomere shortening by telomerase inhibitors 

Hao Zhang, Meng-Hua Yang, Jing-Jing Zhao, Ling Chen, Song-Tao Yu, Xu-Dong Tang, Dian-Chun Fang, Shi-Ming Yang
Article Number: 96
Published online on: 16 March 2026

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Article Open Access

Silencing of SIVA‑1 promotes cisplatin resistance in gastric cancer via the Bcl‑2/BAX‑mediated mitochondria‑dependent apoptosis pathway

Zheng-Yi Shi, Zheng-Rong Ding, Yu-Liang Huang, Yuan-Rui Lei, Hai-Bin Huang, Yan Qing, Miao-Ren Deng, Xu-Man Lu, Xu-Dong Dong, Long-Jie Xia, Sheng Xu, Xiao-Gang Zhong, Lei Li, Fan-Biao Kong, Xiao-Tong Wang
Article Number: 95
Published online on: 13 March 2026

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Article Open Access

Depleting HIF‑1α attenuates the progression of osteosarcoma, but tumorigenicity is sustained through HIF‑independent pathways

Ayaka Kunishima, Takatsune Shimizu, Tetsuya Takimoto, Atsunobu Sagara, Hiroyuki Nobusue, Hidetoshi Hasuwa, Shinya Hasegawa, Yuka Tamaoki, Hitomi Miyake, Yumi Fukuchi, Hideyuki Saya, Akihiro Muto
Article Number: 94
Published online on: 12 March 2026

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Article Open Access

Unveiling the role of ANGPT2 in esophageal cancer: A prognostic factor and potential oncogene

Zhigang Zhai, Zhenyu Xue, Yuan Fang, Yixu Fan, Shijiao Li, Yunpeng Yu, Chuansheng Chen, Kaijun Zhang, Deyu Chen, Xiang Tang, Rui Ling
Article Number: 93
Published online on: 12 March 2026

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Article Open Access

POLQ promotes tumor progression and immunosuppression via ATM‑P53 signaling in endometrial cancer

Ningning Zhu, Juanjuan Wang, Xiaoli Zhang, Kai Tang, Lei Gong, Yi Hu
Article Number: 92
Published online on: 11 March 2026

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Correction Open Access

[Corrigendum] 3‑Bromopyruvate and sodium citrate target glycolysis, suppress survivin, and induce mitochondrial‑mediated apoptosis in gastric cancer cells and inhibit gastric orthotopic transplantation tumor growth

Ting-An Wang, Xiao-Dong Zhang, Xing-Yu Guo, Shu-Lin Xian, Yun-Fei Lu
Article Number: 91
Published online on: 11 March 2026

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Review Open Access

Unveiling the molecular landscape: Long non-coding RNAs in neuroblastoma (Review)

Zidong Xia, Huishan Zhai, Lei Zheng, Cheng Wang
Article Number: 90
Published online on: 09 March 2026

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Retraction Open Access

[Retracted] Erastin sensitizes glioblastoma cells to temozolomide by restraining xCT and cystathionine‑γ‑lyase function

Liangyu Chen, Xinxing Li, Libo Liu, Bo Yu, Yixue Xue, Yunhui Liu
Article Number: 89
Published online on: 09 March 2026

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Review Open Access

Advances in the application of frailty scoring in the diagnosis and management of elderly patients with multiple myeloma (Review)

Junlun Liu, Danyu Li, Chao Li, Zhuoren Chen
Article Number: 88
Published online on: 06 March 2026

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Expression of Concern Open Access

[Expression of Concern] c‑Fos/ERK promotes the progression from pancreatic intraepithelial neoplasia to pancreatic ductal adenocarcinoma 

Lei You, Xiaoxia Ren, Yongxing Du, Wenjing Zhao, Ming Cui, Ge Chen, Yupei Zhao
Article Number: 87
Published online on: 05 March 2026

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Review Open Access

CXCL1 in triple‑negative breast cancer: Mechanisms, challenges, and therapeutic opportunities (Review)

Hiba Al Sayegh, Zahraa Assi, Amjad Kanaan, Mirvat El Sibai
Article Number: 86
Published online on: 03 March 2026

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Article Open Access

Cellular and inflammatory characteristics of patient‑derived glioblastoma organoids during in vitro cultivation

Jessica Nojszewski, Nils Oliver Schröder, Jacqueline Clüver, Jonna Holler, Hajrullah Ahmeti, Michael Synowitz, Janka Held-Feindt
Article Number: 85
Published online on: 02 March 2026

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Retraction Open Access

[Retracted] Growth and differentiation factor‑9 promotes adhesive and motile capacity of prostate cancer cells by up‑regulating FAK and Paxillin via Smad dependent pathway 

Sivan M. Bokobza, Lin Ye, Howard G. Kynaston, Wen G. Jiang
Article Number: 84
Published online on: 02 March 2026

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Article Open Access

Platycodin D sensitizes head and neck squamous cell carcinoma to cisplatin by inducing autophagy arrest

Minji Bae, Min Kyeong Lee, Mi Gyeong Jeong, Yeonseo Lee, Harim Joo, Young Chan Lee, Jung Woo Lee, Su Il Kim, Seong-Gyu Ko, Young-Gyu Eun
Article Number: 83
Published online on: 27 February 2026

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Article Open Access

ACSBG1‑driven lipid reprogramming unveiled: A fatty acid metabolism‑associated prognostic model for lung adenocarcinoma

Panxin Hu, Anan Li
Article Number: 82
Published online on: 27 February 2026

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Article Open Access

Knockdown of CCT2 inhibits the malignant progression of hepatocellular carcinoma cells by impairing STAT3 activation

Chao Li, Lei Yang, Yudong Zhang, Baocheng Zhao, Hao Qu
Article Number: 81
Published online on: 25 February 2026

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Retraction Open Access

[Retracted] Songorine suppresses cell growth and metastasis in epithelial ovarian cancer via the Bcl‑2/Bax and GSK3β/β‑catenin signaling pathways

Hongxia Zhang, Ruifeng Dong, Ping Zhang, Yankui Wang
Article Number: 80
Published online on: 25 February 2026

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June-2026 Volume 55 Issue 6

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review Open Access

HMGB3: A pivotal orchestrator of therapy resistance and cancer stemness in human malignancies (Review)

Ju Zhang, Yifan Sun, Lanyu Wang, Jiayu Gu, Ye Hua, Jianfeng Shao, Ninghan Feng
Article Number: 104
Published online on: 01 April 2026

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Expression of Concern Open Access

[Expression of Concern] 5‑Azacytidine inhibits the proliferation of bladder cancer cells via reversal of the aberrant hypermethylation of the hepaCAM gene

Xiaorong Wang, E. Chen, Xue Yang, Yin Wang, Zhen Quan, Xiaohou Wu, Chunli Luo
Article Number: 103
Published online on: 30 March 2026

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