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Oncology Reports
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Print ISSN: 1021-335X Online ISSN: 1791-2431
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November 2011 Volume 26 Issue 5

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International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

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Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

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Article

Preliminary evidence of the presence of lymphatic vessels immunoreactive for D2-40 and Prox-1 in human pterygium

  • Authors:
    • Anca Maria Cimpean
    • Mihai Poenaru Sava
    • Marius Raica
    • Domenico Ribatti
  • View Affiliations / Copyright

    Affiliations: Department of Histology, ‘Victor Babeş’ University of Medicine and Pharmacy, Timisoara, Romania, Department of Human Anatomy and Histology, School of Medicine, University of Bari, Piazza G. Cesare 11, Policlinico, I-70124 Bari, Italy
  • Pages: 1111-1113
    |
    Published online on: June 8, 2011
       https://doi.org/10.3892/or.2011.1342
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Abstract

Human pterygium is a benign fibrovascular outgrowth of the corneo-conjunctival junction, characterized by tissue remodeling, cellular proliferation, angiogenesis and inflammation. No data are available concerning the presence of lymphatic vessels in this pathological condition. The aim of this study was to evaluate by immunohistochemistry, using antibodies against D2-40, Prox-1 and Ki-67, the presence and the proliferative activity of lymphatic vessels in human pterygium. An increased lymphatic microvessel density was observed in the human pterygium compared to the normal conjunctiva. Moreover, D2-40-positive lymphatic endothelial cells were also actively proliferating, as assessed by Ki-67 immunostaining, while in normal conjunctiva proliferating lymphatic endothelial cells were not detectable. Overall, these data clearly indicate the presence of active proliferating lymphatic vessels in human pterygium, suggesting that active lymphangiogenesis occurs in this pathological condition.

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Copy and paste a formatted citation
Spandidos Publications style
Cimpean AM, Poenaru Sava M, Raica M and Ribatti D: Preliminary evidence of the presence of lymphatic vessels immunoreactive for D2-40 and Prox-1 in human pterygium. Oncol Rep 26: 1111-1113, 2011.
APA
Cimpean, A.M., Poenaru Sava, M., Raica, M., & Ribatti, D. (2011). Preliminary evidence of the presence of lymphatic vessels immunoreactive for D2-40 and Prox-1 in human pterygium. Oncology Reports, 26, 1111-1113. https://doi.org/10.3892/or.2011.1342
MLA
Cimpean, A. M., Poenaru Sava, M., Raica, M., Ribatti, D."Preliminary evidence of the presence of lymphatic vessels immunoreactive for D2-40 and Prox-1 in human pterygium". Oncology Reports 26.5 (2011): 1111-1113.
Chicago
Cimpean, A. M., Poenaru Sava, M., Raica, M., Ribatti, D."Preliminary evidence of the presence of lymphatic vessels immunoreactive for D2-40 and Prox-1 in human pterygium". Oncology Reports 26, no. 5 (2011): 1111-1113. https://doi.org/10.3892/or.2011.1342
Copy and paste a formatted citation
x
Spandidos Publications style
Cimpean AM, Poenaru Sava M, Raica M and Ribatti D: Preliminary evidence of the presence of lymphatic vessels immunoreactive for D2-40 and Prox-1 in human pterygium. Oncol Rep 26: 1111-1113, 2011.
APA
Cimpean, A.M., Poenaru Sava, M., Raica, M., & Ribatti, D. (2011). Preliminary evidence of the presence of lymphatic vessels immunoreactive for D2-40 and Prox-1 in human pterygium. Oncology Reports, 26, 1111-1113. https://doi.org/10.3892/or.2011.1342
MLA
Cimpean, A. M., Poenaru Sava, M., Raica, M., Ribatti, D."Preliminary evidence of the presence of lymphatic vessels immunoreactive for D2-40 and Prox-1 in human pterygium". Oncology Reports 26.5 (2011): 1111-1113.
Chicago
Cimpean, A. M., Poenaru Sava, M., Raica, M., Ribatti, D."Preliminary evidence of the presence of lymphatic vessels immunoreactive for D2-40 and Prox-1 in human pterygium". Oncology Reports 26, no. 5 (2011): 1111-1113. https://doi.org/10.3892/or.2011.1342
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