|
1
|
Giese A, Bjerkvig R, Berens ME and
Westphal M: Cost of migration: invasion of malignant gliomas and
implications for treatment. J Clin Oncol. 21:1624–1636. 2003.
View Article : Google Scholar : PubMed/NCBI
|
|
2
|
Liu TJ, LaFortune T, Honda T, Ohmori O,
Hatakeyama S, Meye T, Jackson D, de Groot J and Yung WK: Inhibition
of both focal adhesion kinase and insulin-like growth factor-I
receptor kinase suppresses glioma proliferation in vitro and in
vivo. Mol Cancer Ther. 6:1357–1367. 2007. View Article : Google Scholar
|
|
3
|
Ekstrand AJ, James CD, Cavenee WK, Seliger
B, Pettersson RF and Collins VP: Genes for epidermal growth factor
receptor, transforming growth factor alpha, and epidermal growth
factor and their expression in human gliomas in vivo. Cancer Res.
51:2164–2172. 1991.PubMed/NCBI
|
|
4
|
Nakamura JL: The epidermal growth factor
receptor in malignant gliomas: pathogenesis and therapeutic
implications. Expert Opin Ther Targets. 11:463–472. 2007.
View Article : Google Scholar : PubMed/NCBI
|
|
5
|
Mellinghoff IK, Wang MY, Vivanco I,
Haas-Kogan DA, Zhu S, Dia EQ, Lu KV, Yoshimoto K, Huang JH, Chute
DJ, Riggs BL, Horvath S, Liau LM, Cavenee WK, Rao PN, Beroukhim R,
Peck TC, Lee JC, Sellers WR, Stokoe D, Prados M, Cloughesy TF,
Sawyers CL and Mischel PS: Molecular determinants of the response
of glioblastomas to EGFR kinase inhibitors. N Engl J Med.
353:2012–2024. 2005. View Article : Google Scholar : PubMed/NCBI
|
|
6
|
Fazioli F, Minichiello L, Matoska V,
Castagnino P, Miki T, Wong WT and Di Fiore PP: Eps8, a substrate
for the epidermal growth factor receptor kinase, enhances
EGF-dependent mitogenic signals. EMBO J. 12:3799–3808.
1993.PubMed/NCBI
|
|
7
|
Maa MC, Lai JR, Lin RW and Leu TH:
Enhancement of tyrosyl phosphorylation and protein expression of
eps8 by v-Src. Biochim Biophys Acta. 1450:341–351. 1999. View Article : Google Scholar : PubMed/NCBI
|
|
8
|
Castagnino P, Biesova Z, Wong WT, Fazioli
F, Gill GN and Di Fiore PP: Direct binding of eps8 to the
juxtamembrane domain of EGFR is phosphotyrosine- and
SH2-independent. Oncogene. 10:723–729. 1995.PubMed/NCBI
|
|
9
|
Matoskova B, Wong WT, Salcini AE, Pelicci
PG and Di Fiore PP: Constitutive phosphorylation of eps8 in tumor
cell lines: relevance to malignant transformation. Mol Cell Biol.
15:3805–3812. 1995.PubMed/NCBI
|
|
10
|
Scita G, Nordstrom J, Carbone R, Tenca P,
Giardina G, Gutkind S, Bjarnegard M, Betsholtz C and Di Fiore PP:
Eps8 and E3B1 transduce signals from Ras to Rac. Nature.
401:290–293. 1999. View
Article : Google Scholar : PubMed/NCBI
|
|
11
|
Scita G, Tenca P, Areces LB, Tocchetti A,
Frittoli E, Giardina G, Ponzanelli I, Sini P, Innocenti M and Di
Fiore PP: An effector region in Eps8 is responsible for the
activation of the Rac-specific GEF activity of Sos-1 and for the
proper localization of the Rac-based actin-polymerizing machine. J
Cell Biol. 154:1031–1044. 2001. View Article : Google Scholar : PubMed/NCBI
|
|
12
|
Chen H, Wu X, Pan ZK and Huang S:
Integrity of SOS1/EPS8/ABI1 tri-complex determines ovarian cancer
metastasis. Cancer Res. 70:9979–9990. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
13
|
Wang H, Teh MT, Ji Y, Patel V,
Firouzabadian S, Patel AA, Gutkind JS and Yeudall WA: EPS8
upregulates FOXM1 expression, enhancing cell growth and motility.
Carcinogenesis. 31:1132–1141. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
14
|
Chen YJ, Shen MR, Chen YJ, Maa MC and Leu
TH: Eps8 decreases chemosensitivity and affects survival of
cervical cancer patients. Mol Cancer Ther. 7:1376–1385. 2008.
View Article : Google Scholar : PubMed/NCBI
|
|
15
|
Maa MC, Lee JC, Chen YJ, Chen YJ, Lee YC,
Wang ST, Huang CC, Chow NH and Leu TH: Eps8 facilitates cellular
growth and motility of colon cancer cells by increasing the
expression and activity of focal adhesion kinase. J Biol Chem.
282:19399–19409. 2007. View Article : Google Scholar : PubMed/NCBI
|
|
16
|
Wang H, Patel V, Miyazaki H, Gutkind JS
and Yeudall WA: Role for EPS8 in squamous carcinogenesis.
Carcinogenesis. 30:165–174. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
17
|
Zhang W, Wang L, Liu Y, Xu J, Zhu G, Cang
H, Li X, Bartlam M, Hensley K, Li G, Rao Z and Zhang XC: Structure
of human lanthionine synthetase C-like protein 1 and its
interaction with Eps8 and glutathione. Genes Dev. 23:1387–1392.
2009. View Article : Google Scholar : PubMed/NCBI
|
|
18
|
Welsch T, Endlich K, Giese T, Buchler MW
and Schmidt J: Eps8 is increased in pancreatic cancer and required
for dynamic actin-based cell protrusions and intercellular
cytoskeletal organization. Cancer Lett. 255:205–218. 2007.
View Article : Google Scholar : PubMed/NCBI
|
|
19
|
Yang TP, Chiou HL, Maa MC and Wang CJ:
Mithramycin inhibits human epithelial carcinoma cell proliferation
and migration involving downregulation of Eps8 expression. Chem
Biol Interact. 183:181–186. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
20
|
Luo C, Ding XF, Sun YB and Han M:
Subcellular location of EPS8 by its expression and preparation of
antiserum. J Nat Sci Hunan Normal University. 31:100–104. 2008.
|
|
21
|
Mangravite LM, Lipschutz JH, Mostov KE and
Giacomini KM: Localization of GFP-tagged concentrative nucleoside
transporters in a renal polarized epithelial cell line. Am J
Physiol Renal Physiol. 280:F879–F885. 2001.PubMed/NCBI
|
|
22
|
Schmid JA, Birbach A, Hofer-Warbinek R,
Pengg M, Burner U, Furtmuller PG, Binder BR and de Martin R:
Dynamics of NF kappa B and Ikappa Balpha studied with green
fluorescent protein (GFP) fusion proteins. Investigation of GFP-p65
binding to DNa by fluorescence resonance energy transfer. J Biol
Chem. 275:17035–17042. 2000. View Article : Google Scholar
|
|
23
|
Lois C, Hong EJ, Pease S, Brown EJ and
Baltimore D: Germline transmission and tissue-specific expression
of transgenes delivered by lentiviral vectors. Science.
295:868–872. 2002. View Article : Google Scholar : PubMed/NCBI
|
|
24
|
Offenhauser N, Borgonovo A, Disanza A,
Romano P, Ponzanelli I, Iannolo G, Di Fiore PP and Scita G: The
eps8 family of proteins links growth factor stimulation to actin
reorganization generating functional redundancy in the Ras/Rac
pathway. Mol Biol Cell. 15:91–98. 2004. View Article : Google Scholar
|
|
25
|
Menna E, Disanza A, Cagnoli C, Schenk U,
Gelsomino G, Frittoli E, Hertzog M, Offenhauser N, Sawallisch C,
Kreienkamp HJ, Gertler FB, Di Fiore PP, Scita G and Matteoli M:
Eps8 regulates axonal filopodia in hippocampal neurons in response
to brain-derived neurotrophic factor (BDNF). PLoS Biol.
7:e10001382009. View Article : Google Scholar : PubMed/NCBI
|
|
26
|
Hecquet C, Lefevre G, Valtink M, Engelmann
K and Mascarelli F: Activation and role of MAP kinase-dependent
pathways in retinal pigment epithelial cells: ERK and RPE cell
proliferation. Invest Ophthalmol Vis Sci. 43:3091–3098.
2002.PubMed/NCBI
|
|
27
|
Wortzel I and Seger R: The ERK cascade:
distinct functions within various subcellular organelles. Genes
Cancer. 2:195–209. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
28
|
Uthoff SM, Eichenberger MR, McAuliffe TL,
Hamilton CJ and Galandiuk S: Wingless-type frizzled protein
receptor signaling and its putative role in human colon cancer. Mol
Carcinog. 31:56–62. 2001. View
Article : Google Scholar : PubMed/NCBI
|
|
29
|
Barker N and Clevers H: Catenins, Wnt
signaling and cancer. Bioessays. 22:961–965. 2000. View Article : Google Scholar : PubMed/NCBI
|
|
30
|
Polakis P: Wnt signaling and cancer. Genes
Dev. 14:1837–1851. 2000.
|
|
31
|
Liu XWL, Zhao S, Ji X, Luo Y and Ling F:
β-Catenin overexpression in malignant glioma and its role in
proliferation and apoptosis in glioblastoma cells. Med Oncol.
28:608–614. 2011.
|
|
32
|
Zhang JHK, Shi Z, Zou J, Wang Y, Jia Z,
Zhang A, Han L, Yue X, Liu N, Jiang T, You Y, Pu P and Kang C: High
β-catenin/Tcf-4 activity confers glioma progression via direct
regulation of AKT2 gene expression. Neuro Oncol. 13:600–609.
2011.
|
|
33
|
Xu M, Shorts-Cary L, Knox AJ,
Kleinsmidt-DeMasters B, Lillehei K and Wierman ME: Epidermal growth
factor receptor pathway substrate 8 is overexpressed in human
pituitary tumors: role in proliferation and survival.
Endocrinology. 150:2064–2071. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
34
|
Kanneganti M, Mino-Kenudson M and
Mizoguchi E: Animal models of colitis-associated carcinogenesis. J
Biomed Biotechnol. 2011:3426372011. View Article : Google Scholar : PubMed/NCBI
|
|
35
|
Nava P, Koch S, Laukoetter MG, Lee WY,
Kolegraff K, Capaldo CT, Beeman N, Addis C, Gerner-Smidt K,
Neumaier I, Skerra A, Li L, Parkos CA and Nusrat A:
Interferon-gamma regulates intestinal epithelial homeostasis
through converging beta-catenin signaling pathways. Immunity.
32:392–402. 2010. View Article : Google Scholar
|
