1
|
Qi X, Jia B, Zhao X and Yu D: Advances in
T-cell checkpoint immunotherapy for head and neck squamous cell
carcinoma. Onco Targets Ther. 10:5745–5754. 2017. View Article : Google Scholar : PubMed/NCBI
|
2
|
Bonomo P, Loi M, Desideri I, Olmetto E,
Delli Paoli C, Terziani F, Greto D, Mangoni M, Scoccianti S,
Simontacchi G, et al: Incidence of skin toxicity in squamous cell
carcinoma of the head and neck treated with radiotherapy and
cetuximab: A systematic review. Crit Rev Oncol Hematol. 120:98–110.
2017. View Article : Google Scholar : PubMed/NCBI
|
3
|
Belcher R, Hayes K, Fedewa S and Chen AY:
Current treatment of head and neck squamous cell cancer. J Surg
Oncol. 110:551–574. 2014. View Article : Google Scholar : PubMed/NCBI
|
4
|
Kundu SK and Nestor M: Targeted therapy in
head and neck cancer. Tumour Biol. 33:707–721. 2012. View Article : Google Scholar : PubMed/NCBI
|
5
|
Shrotriya S, Agarwal R and Sclafani RA: A
perspective on chemoprevention by resveratrol in head and neck
squamous cell carcinoma. Adv Exp Med Biol. 815:333–348. 2015.
View Article : Google Scholar : PubMed/NCBI
|
6
|
Li J, Jiang Z, Li X, Hou Y, Liu F, Li N,
Liu X and Yang L: Natural therapeutic agents for neurodegenerative
diseases from a traditional herbal medicine Pongamia pinnata
(L.) Pierre. Bioorg Med Chem Lett. 25:53–58. 2015. View Article : Google Scholar : PubMed/NCBI
|
7
|
Li W, Sun YN, Yan XT, Yang SY, Kim S, Lee
YM, Koh YS and Kim YH: Flavonoids from Astragalus
membranaceus and their inhibitory effects on LPS-stimulated
pro-inflammatory cytokine production in bone marrow-derived
dendritic cells. Arch Pharm Res. 37:186–192. 2014. View Article : Google Scholar : PubMed/NCBI
|
8
|
Ghribi L, Waffo-Teguo P, Cluzet S, Marchal
A, Marques J, Mérillon JM and Ben Jannet H: Isolation and structure
elucidation of bioactive compounds from the roots of the Tunisian
Ononis angustissima L. Bioorg Med Chem Lett. 25:3825–3830.
2015. View Article : Google Scholar : PubMed/NCBI
|
9
|
Tava A, Pecio L, Stochmal A and Pecetti L:
Clovamide and flavonoids from leaves of Trifolium pratense
and T. pratense subsp. Nivale grown in Italy. Nat Prod
Commun. 10:933–936. 2015.PubMed/NCBI
|
10
|
Mu H, Bai YH, Wang ST, Zhu ZM and Zhang
YW: Research on antioxidant effects and estrogenic effect of
formononetin from Trifolium pratense (red clover).
Phytomedicine. 16:314–319. 2009. View Article : Google Scholar : PubMed/NCBI
|
11
|
Xu N and An J: Formononetin ameliorates
mast cell-mediated allergic inflammation via inhibition of
histamine release and production of pro-inflammatory cytokines. Exp
Ther Med. 14:6201–6206. 2017.PubMed/NCBI
|
12
|
Ma Z, Ji W, Fu Q and Ma S: Formononetin
inhibited the inflammation of LPS-induced acute lung injury in mice
associated with induction of PPAR gamma expression. Inflammation.
36:1560–1566. 2013. View Article : Google Scholar : PubMed/NCBI
|
13
|
Sun M, Zhou T, Zhou L, Chen Q, Yu Y, Yang
H, Zhong K, Zhang X, Xu F, Cai S, et al: Formononetin protects
neurons against hypoxia-induced cytotoxicity through upregulation
of ADAM10 and sAβPPα. J Alzheimers Dis. 28:795–808. 2012.
View Article : Google Scholar : PubMed/NCBI
|
14
|
Wu J, Ke X, Ma N, Wang W, Fu W, Zhang H,
Zhao M, Gao X, Hao X and Zhang Z: Formononetin, an active compound
of Astragalus membranaceus (Fisch) Bunge, inhibits
hypoxia-induced retinal neovascularization via the HIF-1α/VEGF
signaling pathway. Drug Des Devel Ther. 10:3071–3081. 2016.
View Article : Google Scholar : PubMed/NCBI
|
15
|
Wu Y, Zhang X, Li Z, Yan H, Qin J and Li
T: Formononetin inhibits human bladder cancer cell proliferation
and invasiveness via regulation of MiR-21 and PTEN. Food Funct.
8:1061–1066. 2017. View Article : Google Scholar : PubMed/NCBI
|
16
|
Yang Y, Zhao Y, Ai X, Cheng B and Lu S:
Formononetin suppresses the proliferation of human non-small cell
lung cancer through induction of cell cycle arrest and apoptosis.
Int J Clin Exp Pathol. 7:8453–8461. 2014.PubMed/NCBI
|
17
|
Li T, Zhao X, Mo Z, Huang W, Yan H, Ling Z
and Ye Y: Formononetin promotes cell cycle arrest via
downregulation of Akt/Cyclin D1/CDK4 in human prostate cancer
cells. Cell Physiol Biochem. 34:1351–1358. 2014. View Article : Google Scholar : PubMed/NCBI
|
18
|
Zhou R, Xu L, Ye M, Liao M, Du H and Chen
H: Formononetin inhibits migration and invasion of MDA-MB-231 and
4T1 breast cancer cells by suppressing MMP-2 and MMP-9 through
PI3K/AKT signaling pathways. Horm Metab Res. 46:753–760. 2014.
View Article : Google Scholar : PubMed/NCBI
|
19
|
Jin YM, Xu TM, Zhao YH, Wang YC and Cui
MH: In vitro and in vivo anti-cancer activity of formononetin on
human cervical cancer cell line HeLa. Tumour Biol. 35:2279–2284.
2014. View Article : Google Scholar : PubMed/NCBI
|
20
|
Auyeung KK, Law PC and Ko JK: Novel
anti-angiogenic effects of formononetin in human colon cancer cells
and tumor xenograft. Oncol Rep. 28:2188–2194. 2012. View Article : Google Scholar : PubMed/NCBI
|
21
|
Lydiatt WM, Patel SG, O'Sullivan B,
Brandwein MS, Ridge JA, Migliacci JC, Loomis AM and Shah JP: Head
and Neck cancers-major changes in the American Joint Committee on
cancer eighth edition cancer staging manual. CA Cancer J Clin.
67:122–137. 2017. View Article : Google Scholar : PubMed/NCBI
|
22
|
Martino R and Ringash J: Evaluation of
quality of life and organ function in head and neck squamous cell
carcinoma. Hematol Oncol Clin North Am. 22:1239–1256. 2008.
View Article : Google Scholar : PubMed/NCBI
|
23
|
Soni M, Rahardjo TB, Soekardi R,
Sulistyowati Y, Lestariningsih, Yesufu-Udechuku A, Irsan A and
Hogervorst E: Phytoestrogens and cognitive function: A review.
Maturitas. 77:209–220. 2014. View Article : Google Scholar : PubMed/NCBI
|
24
|
Sirotkin AV and Harrath AH: Phytoestrogens
and their effects. Eur J Pharmacol. 741:230–236. 2014. View Article : Google Scholar : PubMed/NCBI
|
25
|
Qadir MI and Cheema BN: Phytoestrogens and
related food components in the prevention of cancer. Crit Rev
Eukaryot Gene Expr. 27:99–112. 2017. View Article : Google Scholar : PubMed/NCBI
|
26
|
Cho IA, You SJ, Kang KR, Kim SG, Oh JS,
You JS, Lee GJ, Seo YS, Kim DK, Kim CS, et al: Biochanin-A induces
apoptosis and suppresses migration in FaDu human pharynx squamous
carcinoma cells. Oncol Rep. 38:2985–2992. 2017. View Article : Google Scholar : PubMed/NCBI
|
27
|
Huh JE, Nam DW, Baek YH, Kang JW, Park DS,
Choi DY and Lee JD: Formononetin accelerates wound repair by the
regulation of early growth response factor-1 transcription factor
through the phosphorylation of the ERK and p38 MAPK pathways. Int
Immunopharmacol. 11:46–54. 2011. View Article : Google Scholar : PubMed/NCBI
|
28
|
Huh JE, Seo DM, Baek YH, Choi DY, Park DS
and Lee JD: Biphasic positive effect of formononetin on metabolic
activity of human normal and osteoarthritic subchondral
osteoblasts. Int Immunopharmacol. 10:500–507. 2010. View Article : Google Scholar : PubMed/NCBI
|
29
|
Hu W and Xiao Z: Formononetin induces
apoptosis of human osteosarcoma cell line U2OS by regulating the
expression of Bcl-2, Bax and MiR-375 in vitro and in vivo. Cell
Physiol Biochem. 37:933–939. 2015. View Article : Google Scholar : PubMed/NCBI
|
30
|
Liu XJ, Li YQ, Chen QY, Xiao SJ and Zeng
SE: Up-regulating of RASD1 and apoptosis of DU-145 human prostate
cancer cells induced by formononetin in vitro. Asian Pac J Cancer
Prev. 15:2835–2839. 2014. View Article : Google Scholar : PubMed/NCBI
|
31
|
Chen J, Zhao X, Ye Y, Wang Y and Tian J:
Estrogen receptor beta-mediated proliferative inhibition and
apoptosis in human breast cancer by calycosin and formononetin.
Cell Physiol Biochem. 32:1790–1797. 2013. View Article : Google Scholar : PubMed/NCBI
|
32
|
Bortner CD and Cidlowski JA: Cell
shrinkage and monovalent cation fluxes: Role in apoptosis. Arch
Biochem Biophys. 462:176–188. 2007. View Article : Google Scholar : PubMed/NCBI
|
33
|
Kass GE, Eriksson JE, Weis M, Orrenius S
and Chow SC: Chromatin condensation during apoptosis requires ATP.
Biochem J. 318:749–752. 1996. View Article : Google Scholar : PubMed/NCBI
|
34
|
Higuchi Y: Chromosomal DNA fragmentation
in apoptosis and necrosis induced by oxidative stress. Biochem
Pharmacol. 66:1527–1535. 2003. View Article : Google Scholar : PubMed/NCBI
|
35
|
Chai F, Truong-Tran AQ, Ho LH and Zalewski
PD: Regulation of caspase activation and apoptosis by cellular zinc
fluxes and zinc deprivation: A review. Immunol Cell Biol.
77:272–278. 1999. View Article : Google Scholar : PubMed/NCBI
|
36
|
Pfeffer CM and Singh ATK: Apoptosis: A
target for anticancer therapy. Int J Mol Sci. 19:4482018.
View Article : Google Scholar :
|
37
|
Zaman S, Wang R and Gandhi V: Targeting
the apoptosis pathway in hematologic malignancies. Leuk Lymphoma.
55:1980–1992. 2014. View Article : Google Scholar : PubMed/NCBI
|
38
|
Goldar S, Khaniani MS, Derakhshan SM and
Baradaran B: Molecular mechanisms of apoptosis and roles in cancer
development and treatment. Asian Pac J Cancer Prev. 16:2129–2144.
2015. View Article : Google Scholar : PubMed/NCBI
|
39
|
Liu H, Su D, Zhang J, Ge S, Li Y, Wang F,
Gravel M, Roulston A, Song Q, Xu W, et al: Improvement of
pharmacokinetic profile of TRAIL via trimer-tag enhances its
antitumor activity in vivo. Sci Rep. 7:89532017. View Article : Google Scholar : PubMed/NCBI
|
40
|
Hassan M, Watari H, AbuAlmaaty A, Ohba Y
and Sakuragi N: Apoptosis and molecular targeting therapy in
cancer. Biomed Res Int. 2014:1508452014. View Article : Google Scholar : PubMed/NCBI
|
41
|
Green DR and Llambi F: Cell death
signaling. Cold Spring Harb Perspect Biol. 1:a0060802015.
View Article : Google Scholar
|
42
|
Suhaili SH, Karimian H, Stellato M, Lee TH
and Aguilar MI: Mitochondrial outer membrane permeabilization: A
focus on the role of mitochondrial membrane structural
organization. Biophys Rev. 9:443–457. 2017. View Article : Google Scholar : PubMed/NCBI
|
43
|
Czabotar PE, Colman PM and Huang DC: Bax
activation by Bim? Cell Death Differ. 16:1187–1191. 2009.
View Article : Google Scholar : PubMed/NCBI
|
44
|
Gogada R, Yadav N, Liu J, Tang S, Zhang D,
Schneider A, Seshadri A, Sun L, Aldaz CM, Tang DG and Chandra D:
Bim, a proapoptotic protein, up-regulated via transcription factor
E2F1-dependent mechanism, functions as a prosurvival molecule in
cancer. J Biol Chem. 288:368–381. 2013. View Article : Google Scholar : PubMed/NCBI
|
45
|
Zhang X, Bi L, Ye Y and Chen J:
Formononetin induces apoptosis in PC-3 prostate cancer cells
through enhancing the Bax/Bcl-2 ratios and regulating the p38/Akt
pathway. Nutr Cancer. 66:656–661. 2014. View Article : Google Scholar : PubMed/NCBI
|
46
|
Peng Q, Deng Z, Pan H, Gu L, Liu O and
Tang Z: Mitogen-activated protein kinase signaling pathway in oral
cancer. Oncol Lett. 15:1379–1388. 2018.PubMed/NCBI
|
47
|
Huang RH, Quan YJ, Chen JH, Wang TF, Xu M,
Ye M, Yuan H, Zhang CJ, Liu XJ and Min ZJ: Osteopontin promotes
cell migration and invasion, and inhibits apoptosis and autophagy
in colorectal cancer by activating the p38 MAPK signaling pathway.
Cell Physiol Biochem. 41:1851–1864. 2017. View Article : Google Scholar : PubMed/NCBI
|
48
|
Lv D, Wu H, Xing R, Shu F, Lei B, Lei C,
Zhou X, Wan B, Yang Y, Zhong L, et al: HnRNP-L mediates bladder
cancer progression by inhibiting apoptotic signaling and enhancing
MAPK signaling pathways. Oncotarget. 8:13586–13599. 2017.PubMed/NCBI
|
49
|
Chen H, Jin ZL and Xu H: MEK/ERK signaling
pathway in apoptosis of SW620 cell line and inhibition effect of
resveratrol. Asian Pac J Trop Med. 9:49–53. 2016. View Article : Google Scholar : PubMed/NCBI
|
50
|
Sun XF and Zhang H: NFKB and NFKBI
polymorphisms in relation to susceptibility of tumour and other
diseases. Histol Histopathol. 22:1387–1398. 2007.PubMed/NCBI
|
51
|
Yap TA, Garrett MD, Walton MI, Raynaud F,
de Bono JS and Workman P: Targeting the PI3K-AKT-mTOR pathway:
Progress, pitfalls, and promises. Curr Opin Pharmacol. 8:393–412.
2008. View Article : Google Scholar : PubMed/NCBI
|
52
|
Alam M, Kashyap T, Pramanik KK, Singh AK,
Nagini S and Mishra R: The elevated activation of NFkB and AP-1 is
correlated with differential regulation of Bcl-2 and associated
with oral squamous cell carcinoma progression and resistance. Clin
Oral Investig. 21:2721–2731. 2017. View Article : Google Scholar : PubMed/NCBI
|
53
|
Wu XY, Xu H, Wu ZF, Chen C, Liu JY, Wu GN,
Yao XQ, Liu FK, Li G and Shen L: Formononetin, a novel FGFR2
inhibitor, potently inhibits angiogenesis and tumor growth in
preclinical models. Oncotarget. 6:44563–44578. 2015. View Article : Google Scholar : PubMed/NCBI
|
54
|
Tyagi A, Gu M, Takahata T, Frederick B,
Agarwal C, Siriwardana S, Agarwal R and Sclafani RA: Resveratrol
selectively induces DNA damage, independent of Smad4 expression, in
its efficacy against human head and neck squamous cell carcinoma.
Clin Cancer Res. 17:5402–5411. 2011. View Article : Google Scholar : PubMed/NCBI
|