|
1
|
ESMO/European Sarcoma Network Working
Group, : Bone sarcomas: ESMO Clinical Practice Guidelines for
diagnosis, treatment and follow-up. Ann Oncol. 25 (Suppl
3):iii113–iii123. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
2
|
Allison DC, Carney SC, Ahlmann ER,
Hendifar A, Chawla S, Fedenko A, Angeles C and Menendez LR: A
meta-analysis of osteosarcoma outcomes in the modern medical era.
Sarcoma. 2012:7048722012. View Article : Google Scholar : PubMed/NCBI
|
|
3
|
Ferrari S, Smeland S, Mercuri M, Bertoni
F, Longhi A, Ruggieri P, Alvegard TA, Picci P, Capanna R, Bernini
G, et al: Italian and scandinavian sarcoma groups: Neoadjuvant
chemotherapy with high-dose Ifosfamide, high-dose methotrexate,
cisplatin, and doxorubicin for patients with localized osteosarcoma
of the extremity: A joint study by the Italian and Scandinavian
Sarcoma Groups. J Clin Oncol. 23:8845–8852. 2005. View Article : Google Scholar : PubMed/NCBI
|
|
4
|
Ai Z, Lu Y, Qiu S and Fan Z: Overcoming
cisplatin resistance of ovarian cancer cells by targeting
HIF-1-regulated cancer metabolism. Cancer Lett. 373:36–44. 2016.
View Article : Google Scholar : PubMed/NCBI
|
|
5
|
Zhu H, Luo H, Zhang W, Shen Z, Hu X and
Zhu X: Molecular mechanisms of cisplatin resistance in cervical
cancer. Drug Des Devel Ther. 10:1885–1895. 2016. View Article : Google Scholar : PubMed/NCBI
|
|
6
|
Zou Z, Chang H, Li H and Wang S: Induction
of reactive oxygen species: An emerging approach for cancer
therapy. Apoptosis. 22:1321–1335. 2017. View Article : Google Scholar : PubMed/NCBI
|
|
7
|
Abbotts R and Madhusudan S: Human AP
endonuclease 1 (APE1): From mechanistic insights to druggable
target in cancer. Cancer Treat Rev. 36:425–435. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
8
|
Whitaker AM, Flynn TS and Freudenthal BD:
Molecular snapshots of APE1 proofreading mismatches and removing
DNA damage. Nat Commun. 9:3992018. View Article : Google Scholar : PubMed/NCBI
|
|
9
|
den Hartog G, Chattopadhyay R, Ablack A,
Hall EH, Butcher LD, Bhattacharyya A, Eckmann L, Harris PR, Das S,
Ernst PB and Crowe SE: Regulation of Rac1 and reactive oxygen
species production in response to infection of gastrointestinal
epithelia. PLoS Pathog. 12:e10053822016. View Article : Google Scholar : PubMed/NCBI
|
|
10
|
Angkeow P, Deshpande SS, Qi B, Liu YX,
Park YC, Jeon BH, Ozaki M and Irani K: Redox factor-1: An
extra-nuclear role in the regulation of endothelial oxidative
stress and apoptosis. Cell Death Differ. 9:717–725. 2002.
View Article : Google Scholar : PubMed/NCBI
|
|
11
|
Tell G, Fantini D and Quadrifoglio F:
Understanding different functions of mammalian AP endonuclease
(APE1) as a promising tool for cancer treatment. Cell Mol Life Sci.
67:3589–3608. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
12
|
Bobola MS, Jankowski PP, Gross ME,
Schwartz J, Finn LS, Blank A, Ellenbogen RG and Silber JR:
Apurinic/apyrimidinic endonuclease is inversely associated with
response to radiotherapy in pediatric ependymoma. Int J Cancer.
129:2370–2379. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
13
|
Wang D, Xiang DB, Yang XQ, Chen LS, Li MX,
Zhong ZY and Zhang YS: APE1 overexpression is associated with
cisplatin resistance in non-small cell lung cancer and targeted
inhibition of APE1 enhances the activity of cisplatin in A549
cells. Lung Cancer. 66:298–304. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
14
|
Wu HH, Cheng YW, Chang JT, Wu TC, Liu WS,
Chen CY and Lee H: Subcellular localization of apurinic
endonuclease 1 promotes lung tumor aggressiveness via NF-kappaB
activation. Oncogene. 29:4330–4340. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
15
|
Al-Attar A, Gossage L, Fareed KR, Shehata
M, Mohammed M, Zaitoun AM, Soomro I, Lobo DN, Abbotts R, Chan S, et
al: Human apurinic/apyrimidinic endonuclease (APE1) is a prognostic
factor in ovarian, gastro-oesophageal and pancreatico-biliary
cancers. Br J Cancer. 102:704–709. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
16
|
Demple B and Sung JS: Molecular and
biological roles of Ape1 protein in mammalian base excision repair.
DNA Repair (Amst). 4:1442–1449. 2005. View Article : Google Scholar : PubMed/NCBI
|
|
17
|
Cesaratto L, Codarin E, Vascotto C,
Leonardi A, Kelley MR, Tiribelli C and Tell G: Specific inhibition
of the redox activity of Ape1/Ref-1 by e3330 blocks Tnf-α-induced
activation of IL-8 production in liver cancer cell lines. PLoS One.
8:e709092013. View Article : Google Scholar : PubMed/NCBI
|
|
18
|
Jiang X, Shan J, Dai N, Zhong Z, Qing Y,
Yang Y, Zhang S, Li C, Sui J, Ren T, et al: Apurinic/apyrimidinic
endonuclease 1 regulates angiogenesis in a transforming growth
factor β-dependent manner in human osteosarcoma. Cancer Sci.
106:1394–1401. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
19
|
Lou D, Zhu L, Ding H, Dai HY and Zou GM:
Aberrant expression of redox protein Ape1 in colon cancer stem
cells. Oncol Lett. 7:1078–1082. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
20
|
Li M, Zhong Z, Zhu J, Xiang D, Dai N, Cao
X, Qing Y, Yang Z, Xie J, Li Z, et al: Identification and
characterization of mitochondrial targeting sequence of human
apurinic/apyrimidinic endonuclease 1. J Biol Chem. 285:14871–14881.
2010. View Article : Google Scholar : PubMed/NCBI
|
|
21
|
Li MX, Shan JL, Wang D, He Y, Zhou Q, Xia
L, Zeng LL, Li ZP, Wang G and Yang ZZ: Human apurinic/apyrimidinic
endonuclease 1 translocalizes to mitochondria after photodynamic
therapy and protects cells from apoptosis. Cancer Sci. 103:882–888.
2012. View Article : Google Scholar : PubMed/NCBI
|
|
22
|
Li M, Vascotto C, Xu S, Dai N, Qing Y,
Zhong Z, Tell G and Wang D: Human AP endonuclease/redox factor
APE1/ref-1 modulates mitochondrial function after oxidative stress
by regulating the transcriptional activity of NRF1. Free Radic Biol
Med. 53:237–248. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
23
|
Yang ZZ, Li MX, Zhang YS, Xiang DB, Dai N,
Zeng LL, Li ZP, Wang G and Wang D: Knock down of the dual
functional protein apurinic/apyrimidinic endonuclease 1 enhances
the killing effect of hematoporphrphyrin derivative-mediated
photodynamic therapy on non-small cell lung cancer cells in vitro
and in a xenograft model. Cancer Sci. 101:180–187. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
24
|
Fishel ML, Wu X, Devlin CM, Logsdon DP,
Jiang Y, Luo M, He Y, Yu Z, Tong Y, Lipking KP, et al:
Apurinic/apyrimidinic endonuclease/redox factor-1 (APE1/Ref-1)
redox function negatively regulates NRF2. J Biol Chem.
290:3057–3068. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
25
|
Wang D, Luo M and Kelley MR: Human
apurinic endonuclease 1 (APE1) expression and prognostic
significance in osteosarcoma: Enhanced sensitivity of osteosarcoma
to DNA damaging agents using silencing RNA APE1 expression
inhibition. Mol Cancer Ther. 3:679–686. 2004.PubMed/NCBI
|
|
26
|
Fishel ML, He Y, Reed AM, Chin-Sinex H,
Hutchins GD, Mendonca MS and Kelley MR: Knockdown of the DNA repair
and redox signaling protein Ape1/Ref-1 blocks ovarian cancer cell
and tumor growth. DNA Repair (Amst). 7:177–186. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
27
|
Barchiesi A, Wasilewski M, Chacinska A,
Tell G and Vascotto C: Mitochondrial translocation of APE1 relies
on the MIA pathway. Nucleic Acids Res. 43:5451–5464. 2015.
View Article : Google Scholar : PubMed/NCBI
|
|
28
|
Vascotto C, Cesaratto L, Zeef LA, Deganuto
M, D'Ambrosio C, Scaloni A, Romanello M, Damante G, Taglialatela G,
Delneri D, et al: Genome-wide analysis and proteomic studies reveal
APE1/Ref-1 multifunctional role in mammalian cells. Proteomics.
9:1058–1074. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
29
|
Bokoch GM and Knaus UG: NADPH oxidases:
Not just for leukocytes anymore! Trends Biochem Sci. 28:502–508.
2003. View Article : Google Scholar : PubMed/NCBI
|
|
30
|
Patil S, Bunderson M, Wilham J and Black
SM: Important role for Rac1 in regulating reactive oxygen species
generation and pulmonary arterial smooth muscle cell growth. Am J
Physiol Lung Cell Mol Physiol. 287:L1314–L1322. 2004. View Article : Google Scholar : PubMed/NCBI
|
|
31
|
Abo A, Pick E, Hall A, Totty N, Teahan CG
and Segal AW: Activation of the NADPH oxidase involves the small
GTP-binding protein p21rac1. Nature. 353:668–670. 1991. View Article : Google Scholar : PubMed/NCBI
|
|
32
|
Irani K, Xia Y, Zweier JL, Sollott SJ, Der
CJ, Fearon ER, Sundaresan M, Finkel T and Goldschmidt-Clermont PJ:
Mitogenic signaling mediated by oxidants in Ras-transformed
fibroblasts. Science. 275:1649–1652. 1997. View Article : Google Scholar : PubMed/NCBI
|
|
33
|
Lőrincz AM, Szarvas G, Smith SM and Ligeti
E: Role of Rac GTPase activating proteins in regulation of NADPH
oxidase in human neutrophils. Free Radic Biol Med. 68:65–71. 2014.
View Article : Google Scholar : PubMed/NCBI
|
|
34
|
Bokoch GM and Zhao T: Regulation of the
phagocyte NADPH oxidase by Rac GTPase. Antioxid Redox Signal.
8:1533–1548. 2006. View Article : Google Scholar : PubMed/NCBI
|
|
35
|
Dan Dunn J, Alvarez LA, Zhang X and
Soldati T: Reactive oxygen species and mitochondria: A nexus of
cellular homeostasis. Redox Biol. 6:472–485. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
36
|
Tomkinson AE, Bonk RT and Linn S:
Mitochondrial endonuclease activities specific for
apurinic/apyrimidinic sites in DNA from mouse cells. J Biol Chem.
263:12532–12537. 1988.PubMed/NCBI
|
|
37
|
Chappell NP, Teng PN, Hood BL, Wang G,
Darcy KM, Hamilton CA, Maxwell GL and Conrads TP: Mitochondrial
proteomic analysis of cisplatin resistance in ovarian cancer. J
Proteome Res. 11:4605–4614. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
38
|
Kulawiec M, Owens KM and Singh KK: Cancer
cell mitochondria confer apoptosis resistance and promote
metastasis. Cancer Biol Ther. 8:1378–1385. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
39
|
Marrache S, Pathak RK and Dhar S:
Detouring of cisplatin to access mitochondrial genome for
overcoming resistance. Proc Natl Acad Sci USA. 111:10444–10449.
2014. View Article : Google Scholar : PubMed/NCBI
|
|
40
|
Joo HK, Lee YR, Park MS, Choi S, Park K,
Lee SK, Kim CS, Park JB and Jeon BH: Mitochondrial APE1/Ref-1
suppressed protein kinase C-induced mitochondrial dysfunction in
mouse endothelial cells. Mitochondrion. 17:42–49. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
41
|
Gatti L, Cassinelli G, Zaffaroni N, Lanzi
C and Perego P: New mechanisms for old drugs: Insights into
DNA-unrelated effects of platinum compounds and drug resistance
determinants. Drug Resist Updat. 20:1–11. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
42
|
Yang Z, Schumaker LM, Egorin MJ, Zuhowski
EG, Guo Z and Cullen KJ: Cisplatin preferentially binds
mitochondrial DNA and voltage-dependent anion channel protein in
the mitochondrial membrane of head and neck squamous cell
carcinoma: Possible role in apoptosis. Clin Cancer Res.
12:5817–5825. 2006. View Article : Google Scholar : PubMed/NCBI
|
