Checkpoint kinase‑1 inhibition and etoposide exhibit a strong synergistic anticancer effect on chronic myeloid leukemia cell line K562 by impairing homologous recombination DNA damage repair
Affiliations: Department of Hematology, Tongji Hospital, Tongji University School of Medicine, Shanghai 200065, P.R. China, Division of Pediatric Hematology/Oncology, Department of Pediatrics, Pennsylvania State University College of Medicine, Hershey, PA 17033, USA, East Hospital, Tongji University School of Medicine, Shanghai 200120, P.R. China, Jake Gittlen Laboratories for Cancer Research, Pennsylvania State University College of Medicine, Hershey, PA 17033, USA, Department of Hematology, The First Affiliated Hospital of Xiamen University and Institute of Hematology, School of Medicine, Xiamen University, Xiamen, Fujian 361003, P.R. China, Department of Pathology, School of Medicine, Southeast University, Nanjing, Jiangsu 210009, P.R. China
- Published online on: September 7, 2020 https://doi.org/10.3892/or.2020.7757
- Pages: 2152-2164
Copyright: © Fan et al. This is an open access article distributed under the terms of Creative Commons Attribution License.