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Regulatory functions of miR‑200b‑3p in tumor development (Review)

  • Authors:
    • Sheng Chen
    • Yifeng Tu
    • Hang Yuan
    • Zhan Shi
    • Yang Guo
    • Wenjing Gong
    • Shiliang Tu
  • View Affiliations / Copyright

    Affiliations: General Surgery, Cancer Center, Department of Colorectal Surgery, Zhejiang Provincial People's Hospital (Affiliated People's Hospital, Hangzhou Medical College), Hangzhou, Zhejiang 310014, P.R. China, The Second Clinical Medical College of Zhejiang Chinese Medical University, Hangzhou, Zhejiang 310014, P.R. China
    Copyright: © Chen et al. This is an open access article distributed under the terms of Creative Commons Attribution License.
  • Article Number: 96
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    Published online on: March 23, 2022
       https://doi.org/10.3892/or.2022.8307
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Abstract

MicroRNAs (miRNAs/miRs), non‑coding single‑stranded RNAs of length 18‑24 nucleotides, can modulate gene expression through post‑transcriptional control. As such, they can influence tumor proliferation, apoptosis, invasion, metastasis as well as chemotherapy resistance by regulating certain downstream genes. In this context, miR‑200b‑3p, one particular member of the miR‑200 family, possesses the ability to suppress tumor progression. However, many studies have suggested that, in certain cases, this miRNA may also promote the development of some tumors due to differences in the microenvironments and molecular backgrounds of different cancers. This review summarizes previous studies on the involvement of miR‑200b‑3p in tumors, including the underlying mechanism.
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Copy and paste a formatted citation
Spandidos Publications style
Chen S, Tu Y, Yuan H, Shi Z, Guo Y, Gong W and Tu S: Regulatory functions of miR‑200b‑3p in tumor development (Review). Oncol Rep 47: 96, 2022.
APA
Chen, S., Tu, Y., Yuan, H., Shi, Z., Guo, Y., Gong, W., & Tu, S. (2022). Regulatory functions of miR‑200b‑3p in tumor development (Review). Oncology Reports, 47, 96. https://doi.org/10.3892/or.2022.8307
MLA
Chen, S., Tu, Y., Yuan, H., Shi, Z., Guo, Y., Gong, W., Tu, S."Regulatory functions of miR‑200b‑3p in tumor development (Review)". Oncology Reports 47.5 (2022): 96.
Chicago
Chen, S., Tu, Y., Yuan, H., Shi, Z., Guo, Y., Gong, W., Tu, S."Regulatory functions of miR‑200b‑3p in tumor development (Review)". Oncology Reports 47, no. 5 (2022): 96. https://doi.org/10.3892/or.2022.8307
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Spandidos Publications style
Chen S, Tu Y, Yuan H, Shi Z, Guo Y, Gong W and Tu S: Regulatory functions of miR‑200b‑3p in tumor development (Review). Oncol Rep 47: 96, 2022.
APA
Chen, S., Tu, Y., Yuan, H., Shi, Z., Guo, Y., Gong, W., & Tu, S. (2022). Regulatory functions of miR‑200b‑3p in tumor development (Review). Oncology Reports, 47, 96. https://doi.org/10.3892/or.2022.8307
MLA
Chen, S., Tu, Y., Yuan, H., Shi, Z., Guo, Y., Gong, W., Tu, S."Regulatory functions of miR‑200b‑3p in tumor development (Review)". Oncology Reports 47.5 (2022): 96.
Chicago
Chen, S., Tu, Y., Yuan, H., Shi, Z., Guo, Y., Gong, W., Tu, S."Regulatory functions of miR‑200b‑3p in tumor development (Review)". Oncology Reports 47, no. 5 (2022): 96. https://doi.org/10.3892/or.2022.8307
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