|
1
|
Khan SA, Amnekar R, Khade B, Barreto SG,
Ramadwar M, Shrikhande SV and Gupta S: p38-MAPK/MSK1-mediated
overexpression of histone H3 serine 10 phosphorylation defines
distance-dependent prognostic value of negative resection margin in
gastric cancer. Clin Epigenetics. 8:882016. View Article : Google Scholar : PubMed/NCBI
|
|
2
|
Matsusaka K, Ushiku T, Urabe M, Fukuyo M,
Abe H, Ishikawa S, Seto Y, Aburatani H, Hamakubo T, Kaneda A and
Fukayama M: Coupling CDH17 and CLDN18 markers for comprehensive
membrane-targeted detection of human gastric cancer. Oncotarget.
7:64168–64181. 2016. View Article : Google Scholar : PubMed/NCBI
|
|
3
|
Wang YY, Jiang WL, Zhang PF, Li GF, Dong
JH and Wang XS: Oct-4 is associated with gastric cancer progression
and prognosis. OncoTargets Ther. 9:517–522. 2016. View Article : Google Scholar : PubMed/NCBI
|
|
4
|
Ford AC, Yuan Y and Moayyedi P:
Helicobacter pylori eradication therapy to prevent gastric
cancer: Systematic review and meta-analysis. Gut. 69:2113–2121.
2020. View Article : Google Scholar : PubMed/NCBI
|
|
5
|
Yang X, Takano Y and Zheng HC: The
pathobiological features of gastrointestinal cancers (Review).
Oncol Lett. 3:961–969. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
6
|
von Lindern M, Fornerod M, van Baal S,
Jaegle M, de Wit T, Buijs A and Grosveld G: The translocation
(6;9), associated with a specific subtype of acute myeloid
leukemia, results in the fusion of two genes, dek and can, and the
expression of a chimeric, leukemia-specific dek-can mRNA. Mol Cell
Biol. 12:1687–1697. 1992. View Article : Google Scholar : PubMed/NCBI
|
|
7
|
Wise-Draper TM, Allen HV, Jones EE, Habash
KB, Matsuo H and Wells SI: Apoptosis inhibition by the human DEK
oncoprotein involves interference with p53 functions. Mol Cell
Biol. 26:7506–7519. 2006. View Article : Google Scholar : PubMed/NCBI
|
|
8
|
Carro MS, Spiga FM, Quarto M, Ninni VD,
Volorio S, Alcalay M and Müller H: DEK expression is controlled by
E2F and deregulated in diverse tumor type. Cell Cycle. 5:1202–1207.
2006. View Article : Google Scholar : PubMed/NCBI
|
|
9
|
Liu G, Xiong D, Zeng J, Xu G, Xiao R, Chen
B and Huang Z: Prognostic role of DEK in human solid tumors: A
meta-analysis. Oncotarget. 8:98985–98992. 2017. View Article : Google Scholar : PubMed/NCBI
|
|
10
|
Kappes F, Waldmann T, Mathew V, Yu J,
Zhang L, Khodadoust MS, Chinnaiyan AM, Luger K, Erhardt S,
Schneider R and Markovitz DM: The DEK oncoprotein is a Su(var) that
is essential to heterochromatin integrity. Genes Dev. 25:673–678.
2011. View Article : Google Scholar : PubMed/NCBI
|
|
11
|
Fu GK, Grosveld G and Markovitz DM: DEK,
an autoantigen involved in a chromosomal translocation in acute
myelogenous leukemia, binds to the HIV-2 enhancer. Proc Natl Acad
Sci. 94:1811–1815. 1997. View Article : Google Scholar : PubMed/NCBI
|
|
12
|
McGarvey T, Rosonina E, McCracken S, Li Q,
Arnaout R, Mientjes E, Nickerson JA, Awrey D, Greenblatt J,
Grosveld G and Blencowe BJ: The acute myeloid leukemia-associated
protein, DEK, forms a splicing-dependent interaction with
exon-product complexes. J Cell Biol. 150:309–320. 2000. View Article : Google Scholar : PubMed/NCBI
|
|
13
|
Soares LMM, Zanier K, Mackereth C, Sattler
M and Valcárcel J: Intron removal requires proofreading of
U2AF/3′splice site recognition by DEK. Science. 312:1961–1965.
2006. View Article : Google Scholar : PubMed/NCBI
|
|
14
|
Waldmann T: Structure-specific binding of
the proto-oncogene protein DEK to DNA. Nucleic Acids Res.
31:7003–7010. 2003. View Article : Google Scholar : PubMed/NCBI
|
|
15
|
Alexiadis V, Waldmann T, Andersen J, Mann
M, Knippers R and Gruss C: The protein encoded by the
proto-oncogene DEK changes the topology of chromatin and reduces
the efficiency of DNA replication in a chromatin-specific manner.
Genes Dev. 14:1308–1312. 2000. View Article : Google Scholar : PubMed/NCBI
|
|
16
|
Kavanaugh GM, Wise-Draper TM, Morreale RJ,
Morrison MA, Gole B, Schwemberger S, Tichy ED, Lu L, Babcock GF,
Wells JM, et al: The human DEK oncogene regulates DNA damage
response signaling and repair. Nucleic Acids Res. 39:7465–7476.
2011. View Article : Google Scholar : PubMed/NCBI
|
|
17
|
Waldmann T, Scholten I, Kappes F, Hu HG
and Knippers R: The DEK protein-an abundant and ubiquitous
constituent of mammalian chromatin. Gene. 343:1–9. 2004. View Article : Google Scholar : PubMed/NCBI
|
|
18
|
Modrek B and Lee C: A genomic view of
alternative splicing. Nat Genet. 30:13–19. 2002. View Article : Google Scholar : PubMed/NCBI
|
|
19
|
Pan Q, Shai O, Lee LJ, Frey BJ and
Blencowe BJ: Deep surveying of alternative splicing complexity in
the human transcriptome by high-throughput sequencing. Nat Genet.
40:1413–1415. 2008. View
Article : Google Scholar : PubMed/NCBI
|
|
20
|
Chen J and Weiss WA: Alternative splicing
in cancer: Implications for biology and therapy. Oncogene. 34:1–14.
2015. View Article : Google Scholar : PubMed/NCBI
|
|
21
|
Kress TL and Guthrie C: Accurate RNA
siting and splicing gets help from a DEK-Hand. Science.
312:1886–1887. 2006. View Article : Google Scholar : PubMed/NCBI
|
|
22
|
Wise-Draper TM, Mintz-Cole RA, Morris TA,
Simpson DS, Wikenheiser-Brokamp KA, Currier MA, Cripe TP, Grosveld
GC and Wells SI: Overexpression of the Cellular DEK protein
promotes epithelial transformation in vitro and in vivo. Cancer
Res. 69:1792–1799. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
23
|
Pease NA, Wise-Draper T and Privette
Vinnedge L: Dissecting the potential interplay of DEK functions in
inflammation and cancer. J Oncol. 2015:1065172015. View Article : Google Scholar : PubMed/NCBI
|
|
24
|
Piao J, Shang Y, Liu S, Piao Y, Cui X, Li
Y and Lin Z: High expression of DEK predicts poor prognosis of
gastric adenocarcinoma. Diagn Pathol. 9:672014. View Article : Google Scholar : PubMed/NCBI
|
|
25
|
Ou Y, Xia R, Kong F, Zhang X, Yu S, Jiang
L and Zheng L: Overexpression of DEK is an indicator of poor
prognosis in patients with gastric adenocarcinoma. Oncol Lett.
11:1823–1828. 2016. View Article : Google Scholar : PubMed/NCBI
|
|
26
|
Lin KH and Tsai CY: Overexpression of DEK
in human gastric carcinoma and its clinicopathological
significance. J Clin Oncol. 33:75. 2015. View Article : Google Scholar
|
|
27
|
Wang J, Wen T, Li Z, Che X, Gong L, Jiao
Z, Qu X and Liu Y: CD36 upregulates DEK transcription and promotes
cell migration and invasion via GSK-3β/β-catenin-mediated
epithelial-to-mesenchymal transition in gastric cancer. Aging
(Albany NY). 13:1883–1897. 2020. View Article : Google Scholar : PubMed/NCBI
|
|
28
|
Hui W, Ma X, Zan Y, Song L, Zhang S and
Dong L: MicroRNA-1292-5p inhibits cell growth, migration and
invasion of gastric carcinoma by targeting DEK. Am J Cancer Res.
8:1228–1238. 2018.PubMed/NCBI
|
|
29
|
Zhang W, Liao K and Liu D: MiR-138-5p
inhibits the proliferation of gastric cancer cells by targeting
DEK. Cancer Manag Res. 12:8137–8147. 2020. View Article : Google Scholar : PubMed/NCBI
|
|
30
|
Livak KJ and Schmittgen TD: Analysis of
relative gene expression data using real-time quantitative PCR and
the 2(−Delta Delta C(T)) method. Methods. 25:402–408. 2001.
View Article : Google Scholar : PubMed/NCBI
|
|
31
|
Kim D, Pertea G, Trapnell C, Pimentel H,
Kelley R and Salzberg SL: TopHat2: Accurate alignment of
transcriptomes in the presence of insertions, deletions and gene
fusions. Genome Biol. 14:R362013. View Article : Google Scholar : PubMed/NCBI
|
|
32
|
Trapnell C, Williams BA, Pertea G,
Mortazavi A, Kwan G, van Baren MJ, Salzberg SL, Wold BJ and Pachter
L: Transcript assembly and quantification by RNA-Seq reveals
unannotated transcripts and isoform switching during cell
differentiation. Nat Biotechnol. 28:511–515. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
33
|
Robinson MD, McCarthy DJ and Smyth GK:
edgeR: A Bioconductor package for differential expression analysis
of digital gene expression data. Bioinformatics. 26:139–140. 2010.
View Article : Google Scholar : PubMed/NCBI
|
|
34
|
Jin L, Li G, Yu D, Huang W, Cheng C, Liao
S, Wu Q and Zhang Y: Transcriptome analysis reveals the complexity
of alternative splicing regulation in the fungus Verticillium
dahliae. BMC Genomics. 18:1302017. View Article : Google Scholar : PubMed/NCBI
|
|
35
|
Xia H, Chen D, Wu Q, Wu G, Zhou Y, Zhang Y
and Zhang L: CELF1 preferentially binds to exon-intron boundary and
regulates alternative splicing in HeLa cells. Biochim Biophys Acta
Gene Regul Mech. 1860:911–921. 2017. View Article : Google Scholar : PubMed/NCBI
|
|
36
|
Xie C, Mao X, Huang J, Ding Y, Wu J, Dong
S, Kong L, Gao G, Li CY and Wei L: KOBAS 2.0: A web server for
annotation and identification of enriched pathways and diseases.
Nucleic Acids Res. 39:W316–W322. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
37
|
Young MD, Wakefield MJ, Smyth GK and
Oshlack A: Gene ontology analysis for RNA-seq: Accounting for
selection bias. Genome Biol. 11:R142010. View Article : Google Scholar : PubMed/NCBI
|
|
38
|
Bartha Á and Győrffy B: TNMplot.com: A web
tool for the comparison of gene expression in normal, tumor and
metastatic tissues. Int J Mol Sci. 22:26222021. View Article : Google Scholar : PubMed/NCBI
|
|
39
|
Szász AM, Lánczky A, Nagy Á, Förster S,
Hark K, Green JE, Boussioutas A, Busuttil R, Szabó A and Győrffy B:
Cross-validation of survival associated biomarkers in gastric
cancer using transcriptomic data of 1,065 patients. Oncotarget.
7:49322–49333. 2016. View Article : Google Scholar : PubMed/NCBI
|
|
40
|
Grill JI, Neumann J, Ofner A, Marschall
MK, Zierahn H, Herbst A, Wolf E and Kolligs FT: Dro1/Ccdc80
inactivation promotes AOM/DSS-induced colorectal carcinogenesis and
aggravates colitis by DSS in mice. Carcinogenesis. 39:1176–1184.
2018. View Article : Google Scholar : PubMed/NCBI
|
|
41
|
Liu M, Guo S and Stiles JK: The emerging
role of CXCL10 in cancer (Review). Oncol Lett. 2:583–589. 2011.
View Article : Google Scholar : PubMed/NCBI
|
|
42
|
Chen LH, Liao CY, Lai LC, Tsai MH and
Chuang EY: Semaphorin 6A attenuates the migration capability of
lung cancer cells via the NRF2/HMOX1 Axis. Sci Rep. 9:133022019.
View Article : Google Scholar : PubMed/NCBI
|
|
43
|
Mizuguchi Y, Specht S, Lunz JG, Isse K,
Corbitt N, Takizawa T and Demetris AJ: SPRR2A enhances p53
deacetylation through HDAC1 and down regulates p21 promoter
activity. BMC Mol Biol. 13:202012. View Article : Google Scholar : PubMed/NCBI
|
|
44
|
Li TF, Zeng HJ, Shan Z, Ye RY, Cheang TY,
Zhang YJ, Lu SH, Zhang Q, Shao N and Lin Y: Overexpression of
kinesin superfamily members as prognostic biomarkers of breast
cancer. Cancer Cell Int. 20:1232020. View Article : Google Scholar : PubMed/NCBI
|
|
45
|
Lee HW, Park YM, Lee SJ, Cho HJ, Kim DH,
Lee JI, Kang MS, Seol HJ, Shim YM, Nam DH, et al: Alpha-smooth
muscle actin (ACTA2) is required for metastatic potential of human
lung adenocarcinoma. Clin Cancer Res. 19:5879–5889. 2013.
View Article : Google Scholar : PubMed/NCBI
|
|
46
|
Nagano K, Imai S, Zhao X, Yamashita T,
Yoshioka Y, Abe Y, Mukai Y, Kamada H, Nakagawa S, Tsutsumi Y and
Tsunoda S: Identification and evaluation of metastasis-related
proteins, oxysterol binding protein-like 5 and calumenin, in lung
tumors. Int J Oncol. 47:195–203. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
47
|
Mansour MR, He S, Li Z, Lobbardi R,
Abraham BJ, Hug C, Rahman S, Leon TE, Kuang YY, Zimmerman MW, et
al: JDP2: An oncogenic bZIP transcription factor in T cell acute
lymphoblastic leukemia. J Exp Med. 215:1929–1945. 2018. View Article : Google Scholar : PubMed/NCBI
|
|
48
|
Cairns J, Fridley BL, Jenkins GD, Zhuang
Y, Yu J and Wang L: Differential roles of ERRFI1 in EGFR and AKT
pathway regulation affect cancer proliferation. EMBO Rep.
19:e447672018. View Article : Google Scholar : PubMed/NCBI
|
|
49
|
Li D, Liu S, Xu J, Chen L, Xu C, Chen F,
Xu Z, Zhang Y, Xia S, Shao Y and Wang Y: Ferroptosis-related gene
CHAC1 is a valid indicator for the poor prognosis of kidney renal
clear cell carcinoma. J Cell Mol Med. 25:3610–3621. 2021.
View Article : Google Scholar : PubMed/NCBI
|
|
50
|
Chiu M, Taurino G, Bianchi MG, Kilberg MS
and Bussolati O: Asparagine synthetase in cancer: Beyond acute
lymphoblastic leukemia. Front Oncol. 9:14802019. View Article : Google Scholar : PubMed/NCBI
|
|
51
|
Du F, Sun L, Chu Y, Li T, Lei C, Wang X,
Jiang M, Min Y, Lu Y, Zhao X, et al: DDIT4 promotes gastric cancer
proliferation and tumorigenesis through the p53 and MAPK pathways.
Cancer Commun (Lond). 38:452018. View Article : Google Scholar : PubMed/NCBI
|
|
52
|
Yin S, Chen F, Ye P and Yang G:
Overexpression of FAM3C protein as a novel biomarker for
epithelial-mesenchymal transition and poor outcome in gastric
cancer. Int J Clin Exp Pathol. 11:4247–4256. 2018.PubMed/NCBI
|
|
53
|
Chan YC, Chang YC, Chuang HH, Yang YC, Lin
YF, Huang MS, Hsiao M, Yang CJ and Hua KT: Overexpression of PSAT1
promotes metastasis of lung adenocarcinoma by suppressing the
IRF1-IFNγ axis. Oncogene. 39:2509–2522. 2020. View Article : Google Scholar : PubMed/NCBI
|
|
54
|
Rawat V, Malvi P, Della Manna D, Yang ES,
Bugide S, Zhang X, Gupta R and Wajapeyee N: PSPH promotes melanoma
growth and metastasis by metabolic deregulation-mediated
transcriptional activation of NR4A1. Oncogene. 40:2448–2462. 2021.
View Article : Google Scholar : PubMed/NCBI
|
|
55
|
Meng Q, Ren M, Li Y and Song X:
LncRNA-RMRP Acts as an oncogene in lung cancer. PLoS One.
11:e01648452016. View Article : Google Scholar : PubMed/NCBI
|
|
56
|
Wang ET, Sandberg R, Luo S, Khrebtukova I,
Zhang L, Mayr C, Kingsmore SF, Schroth GP and Burge CB: Alternative
isoform regulation in human tissue transcriptomes. Nature.
456:470–476. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
57
|
Duan Z, Zhang J, Choy E, Harmon D, Liu X,
Nielsen P, Mankin H, Gray NS and Hornicek FJ: Systematic kinome
shRNA screening identifies CDK11 (PITSLRE) kinase expression is
critical for osteosarcoma cell growth and proliferation. Clin
Cancer Res. 18:4580–4588. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
58
|
Byun HJ, Kim BR, Yoo R, Park SY and Rho
SB: sMEK1 enhances gemcitabine anti-cancer activity through
inhibition of phosphorylation of Akt/mTOR. Apoptosis. 17:1095–1103.
2012. View Article : Google Scholar : PubMed/NCBI
|
|
59
|
Yang Q, Zhu M, Wang Z, Li H, Zhou W, Xiao
X, Zhang B, Hu W and Liu J: 4.1N is involved in a
flotillin-1/β-catenin/Wnt pathway and suppresses cell proliferation
and migration in non-small cell lung cancer cell lines. Tumour
Biol. 37:12713–12723. 2016. View Article : Google Scholar : PubMed/NCBI
|
|
60
|
Durinck S, Stawiski EW, Pavía-Jiménez A,
Modrusan Z, Kapur P, Jaiswal BS, Zhang N, Toffessi-Tcheuyap V,
Nguyen TT, Pahuja KB, et al: Spectrum of diverse genomic
alterations Define non-clear cell renal carcinoma subtypes. Nat
Genet. 47:13–21. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
61
|
Starrett GJ, Luengas EM, McCann JL,
Ebrahimi D, Temiz NA, Love RP, Feng Y, Adolph MB, Chelico L, Law
EK, et al: The DNA cytosine deaminase APOBEC3H haplotype I likely
contributes to breast and lung cancer mutagenesis. Nat Commun.
7:129182016. View Article : Google Scholar : PubMed/NCBI
|
|
62
|
Lin D, Dong X, Wang K, Wyatt AW, Crea F,
Xue H, Wang Y, Wu R, Bell RH, Haegert A, et al: Identification of
DEK as a potential therapeutic target for neuroendocrine prostate
cancer. Oncotarget. 6:1806–1820. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
63
|
Datta A, Adelson ME, Mogilevkin Y,
Mordechai E, Sidi AA and Trama JP: Oncoprotein DEK as a tissue and
urinary biomarker for bladder cancer. BMC Cancer. 11:2342011.
View Article : Google Scholar : PubMed/NCBI
|
|
64
|
Wise-Draper T, Sendilnathan A,
Palackdharry S, Pease N, Qualtieri J, Butler R, Sadraei NH, Morris
JC, Patil Y, Wilson K, et al: Decreased plasma DEK oncogene levels
correlate with p16-Negative disease and advanced tumor stage in a
case-control study of patients with head and neck squamous cell
carcinoma. Transl Oncol. 11:168–174. 2018. View Article : Google Scholar : PubMed/NCBI
|
|
65
|
Biyik-Sit R, Kruer T, Dougherty S, Bradley
JA, Wilkey DW, Merchant ML, Trent JO and Clem BF: Nuclear pyruvate
kinase M2 (PKM2) contributes to phosphoserine aminotransferase 1
(PSAT1)-mediated cell migration in EGFR-activated lung cancer
cells. Cancers (Basel). 13:39382021. View Article : Google Scholar : PubMed/NCBI
|
|
66
|
Ferraro A, Schepis F, Leone V, Federico A,
Borbone E, Pallante P, Berlingieri MT, Chiappetta G, Monaco M,
Palmieri D, et al: Tumor suppressor role of the CL2/DRO1/CCDC80
gene in thyroid carcinogenesis. J Clin Endocrinol Metab.
98:2834–2843. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
67
|
De S, Cipriano R, Jackson MW and Stark GR:
Overexpression of kinesins mediates docetaxel resistance in breast
cancer cells. Cancer Res. 69:8035–8042. 2009. View Article : Google Scholar : PubMed/NCBI
|
