
Recent findings on miR‑370 expression, regulation and functions in cancer (Review)
- Authors:
- Lingling Ye
- Jinqiu Wang
- Kui Yi
- Fen Wang
- Jinyan Wang
- Hao Wu
- Hui Yang
- Zhaohui Yang
- Quan'an Zhang
-
Affiliations: Department of Oncology, The Affiliated Jiangning Hospital with Nanjing Medical University, Nanjing, Jiangsu 211000, P.R. China, Department of Oncology, Dafeng People's Hospital, Yancheng, Jiangsu 224000, P.R. China, Department of General Surgery, The Affiliated Jiangning Hospital with Nanjing Medical University, Nanjing, Jiangsu 211000, P.R. China - Published online on: March 3, 2023 https://doi.org/10.3892/or.2023.8516
- Article Number: 79
-
Copyright: © Ye et al. This is an open access article distributed under the terms of Creative Commons Attribution License.
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Abstract
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Chen X, Mangala LS, Rodriguez-Aguayo C, Kong X, Lopez-Berestein G and Sood AK: RNA interference-based therapy and its delivery systems. Cancer Metastasis Rev. 1:107–124. 2018. View Article : Google Scholar : PubMed/NCBI | |
Seitz H: Issues in current microRNA target identification methods. RNA Biol. 14:831–834. 2017. View Article : Google Scholar : PubMed/NCBI | |
Shi Y, Yang F, Wei S and Xu G: Identification of key genes affecting results of hyperthermia in osteosarcoma based on integrative ChIP-Seq/TargetScan analysis. Med Sci Monit. 23:2042–2048. 2017. View Article : Google Scholar : PubMed/NCBI | |
Loher P and Rigoutsos I: Interactive exploration of RNA22 microRNA target predictions. Bioinformatics. 28:3322–3323. 2012. View Article : Google Scholar : PubMed/NCBI | |
Chen Y and Wang X: miRDB: An online database for prediction of functional microRNA targets. Nucleic Acids Res. 48:D127–D131. 2020. View Article : Google Scholar : PubMed/NCBI | |
Rennie W, Liu C, Carmack CS, Wolenc A, Kanoria S, Lu J, Long D and Ding Y: STarMir: A web server for prediction of microRNA binding sites. Nucleic Acids Res. 42:W114–W118. 2014. View Article : Google Scholar : PubMed/NCBI | |
Akhtar MM, Micolucci L, Islam MS, Olivieri F and Procopio AD: Bioinformatic tools for microRNA dissection. Nucleic Acids Res. 44:24–44. 2016. View Article : Google Scholar : PubMed/NCBI | |
Rincón-Riveros A, Morales D, Rodríguez JA, Villegas VE and López-Kleine L: Bioinformatic tools for the analysis and prediction of ncRNA interactions. Int J Mol Sci. 22:113972021. View Article : Google Scholar : PubMed/NCBI | |
Reczko M, Maragkakis M, Alexiou P, Grosse I and Hatzigeorgiou AG: Functional microRNA targets in protein coding sequences. Bioinformatics. 6:771–776. 2012. View Article : Google Scholar : PubMed/NCBI | |
Qin X, Zhang J, Lin Y, Sun XM, Zhang JN and Cheng ZQ: Identification of MiR-211-5p as a tumor suppressor by targeting ACSL4 in Hepatocellular Carcinoma. J Transl Med. 18:3262020. View Article : Google Scholar : PubMed/NCBI | |
Dou XQ, Chen XJ, Zhou Q, Wen MX, Zhang SZ and Zhang SQ: miR-335 modulates Numb alternative splicing via targeting RBM10 in endometrial cancer. Kaohsiung J Med Sci. 36:171–177. 2020. View Article : Google Scholar : PubMed/NCBI | |
Sang K, Yi T, Huang X, Pan C, Zhou J and Yu L: MiR-370-5p inhibits the progression of breast cancer via targeting LUC7L3. J Recept Signal Transduct Res. 41:442–450. 2021. View Article : Google Scholar : PubMed/NCBI | |
Bridges MC, Daulagala AC and Kourtidis A: LNCcation: lncRNA localization and function. J Cell Biol. 220:e2020090452021. View Article : Google Scholar : PubMed/NCBI | |
Herman AB, Tsitsipatis D and Gorospe M: Integrated lncRNA function upon genomic and epigenomic regulation. Mol Cell. 82:2252–2266. 2022. View Article : Google Scholar : PubMed/NCBI | |
Wu P, Mo Y, Peng M, Tang T, Zhong Y, Deng X, Xiong F, Guo C, Wu X, Li Y, et al: Emerging role of tumor-related functional peptides encoded by lncRNA and circRNA. Mol Cancer. 19:222020. View Article : Google Scholar : PubMed/NCBI | |
Tay Y, Rinn J and Pandolfi PP: The multilayered complexity of ceRNA crosstalk and competition. Nature. 505:344–352. 2014. View Article : Google Scholar : PubMed/NCBI | |
Li C, Ge Q, Liu J, Zhang Q, Wang C, Cui K and Chen Z: Effects of miR-1236-3p and miR-370-5p on activation of p21 in various tumors and its inhibition on the growth of lung cancer cells. Tumour Biol. 39:10104283177108242017. View Article : Google Scholar : PubMed/NCBI | |
Zou Y, Zhong C, Hu Z and Duan S: MiR-873-5p: A potential molecular marker for cancer diagnosis and prognosis. Front Oncol. 11:7437012021. View Article : Google Scholar : PubMed/NCBI | |
Wang C, Chen Z, Ge Q, Hu J, Li F, Hu J, Xu H, Ye Z and Li LC: Up-regulation of p21(WAF1/CIP1) by miRNAs and its implications in bladder cancer cells. FEBS Lett. 588:4654–4664. 2014. View Article : Google Scholar : PubMed/NCBI | |
Li S, Wang C, Yu X, Wu H, Hu J, Wang S and Ye Z: miR-3619-5p inhibits prostate cancer cell growth by activating CDKN1A expression. Oncol Rep. 37:241–248. 2017. View Article : Google Scholar : PubMed/NCBI | |
Wu F and Zhou J: CircAGFG1 promotes cervical cancer progression via miR-370-3p/RAF1 signaling. BMC Cancer. 19:10672019. View Article : Google Scholar : PubMed/NCBI | |
Shen X, Zuo X, Zhang W, Bai Y, Qin X and Hou N: MiR-370 promotes apoptosis in colon cancer by directly targeting MDM4. Oncol Lett. 15:1673–1679. 2018.PubMed/NCBI | |
Xiong H, Yu J, Jia G, Su Y, Zhang J, Xu Q and Sun X: Emerging roles of circUBAP2 targeting miR-370-3p in proliferation, apoptosis, and invasion of papillary thyroid cancer cells. Hum Cell. 34:1866–1877. 2021. View Article : Google Scholar : PubMed/NCBI | |
Wang DW, Su F, Zhang T, Yang TC, Wang HQ, Yang LJ, Zhou FF and Feng MH: The miR-370/UQCRC2 axis facilitates tumorigenesis by regulating epithelial-mesenchymal transition in Gastric Cancer. J Cancer. 11:5042–5055. 2020. View Article : Google Scholar : PubMed/NCBI | |
Wang Y, Ding M, Yuan X, Jiao R, Zhu D, Huang W, Deng W and Liu Y: lncRNA SNHG15 promotes ovarian cancer progression through regulated CDK6 via sponging miR-370-3p. Biomed Res Int. 2021:93945632021. View Article : Google Scholar : PubMed/NCBI | |
Mao J, Wang L, Wu J, Wang Y, Wen H, Zhu X, Wang B and Yang H: miR-370-3p as a novel biomarker promotes breast cancer progression by targeting FBLN5. Stem Cells Int. 2021:46498902021. View Article : Google Scholar : PubMed/NCBI | |
Maftouh M, Avan A, Funel N, Frampton AE, Fiuji H, Pelliccioni S, Castellano L, Galla V, Peters GJ and Giovannetti E: miR-211 modulates gemcitabine activity through downregulation of ribonucleotide reductase and inhibits the invasive behavior of pancreatic cancer cells. Nucleosides Nucleotides Nucleic Acids. 33:384–393. 2014. View Article : Google Scholar : PubMed/NCBI | |
Chang KW, Chu TH, Gong NR, Chiang WF, Yang CC, Liu CJ, Wu CH and Lin SC: miR-370 modulates insulin receptor substrate-1 expression and inhibits the tumor phenotypes of oral carcinoma. Oral Dis. 19:611–619. 2013. View Article : Google Scholar : PubMed/NCBI | |
Yungang W, Xiaoyu L, Pang T, Wenming L and Pan X: miR-370 targeted FoxM1 functions as a tumor suppressor in laryngeal squamous cell carcinoma (LSCC). Biomed Pharmacother. 68:149–154. 2014. View Article : Google Scholar : PubMed/NCBI | |
Chen F, Feng Z, Zhu J, Liu P, Yang C, Huang R and Deng Z: Emerging roles of circRNA_NEK6 targeting miR-370-3p in the proliferation and invasion of thyroid cancer via Wnt signaling pathway. Cancer Biol Ther. 19:1139–1152. 2018. View Article : Google Scholar : PubMed/NCBI | |
Han Y, Yang X, Zhao N, Peng J, Gao H and Qiu X: Alpinumisoflavone induces apoptosis in esophageal squamous cell carcinoma by modulating miR-370/PIM1 signaling. Am J Cancer Res. 6:2755–2771. 2016.PubMed/NCBI | |
Sun G, Hou YB, Jia HY, Bi XH, Yu L and Chen DJ: MiR-370 promotes cell death of liver cancer cells by Akt/FoxO3a signalling pathway. Eur Rev Med Pharmacol Sci. 20:2011–2019. 2016.PubMed/NCBI | |
Liu Z, Ma M, Yan L, Chen S, Li S, Yang D, Wang X, Xiao H, Deng H, Zhu H, et al: miR-370 regulates ISG15 expression and influences IFN-α sensitivity in hepatocellular carcinoma cells. Cancer Biomark. 22:453–466. 2018. View Article : Google Scholar : PubMed/NCBI | |
Chen Q, Zhang J, He Y and Wang Y: hsa_circ_0061140 knockdown reverses FOXM1-mediated cell growth and metastasis in ovarian cancer through miR-370 sponge activity. Mol Ther Nucleic Acids. 13:55–63. 2018. View Article : Google Scholar : PubMed/NCBI | |
Chen J, Liu G, Wu Y, Ma J, Wu H, Xie Z, Chen S, Yang Y, Wang S, Shen P, et al: CircMYO10 promotes osteosarcoma progression by regulating miR-370-3p/RUVBL1 axis to enhance the transcriptional activity of β-catenin/LEF1 complex via effects on chromatin remodeling. Mol Cancer. 18:1502019. View Article : Google Scholar : PubMed/NCBI | |
Wei S and Ma W: MiR-370 functions as oncogene in melanoma by direct targeting pyruvate dehydrogenase B. Biomed Pharmacother. 90:278–286. 2017. View Article : Google Scholar : PubMed/NCBI | |
García-Ortí L, Cristóbal I, Cirauqui C, Guruceaga E, Marcotegui N, Calasanz MJ, Castello-Cros R and Odero MD: Integration of SNP and mRNA arrays with microRNA profiling reveals that MiR-370 is upregulated and targets NF1 in acute myeloid leukemia. PLoS One. 7:e477172012. View Article : Google Scholar : PubMed/NCBI | |
Ali MM, Mohamed RH, Sayed AA, Ahmed S, Yassin DA and El-Sayed WM: miR-370 is better than miR-375 as a non-invasive diagnostic biomarker for pediatric acute myeloid leukemia patients. Cancer Biomark. 34:403–411. 2022. View Article : Google Scholar : PubMed/NCBI | |
Jin Y, Zhang M, Duan R, Yang J, Yang Y, Wang J, Jiang C, Yao B, Li L, Yuan H, et al: Long noncoding RNA FGF14-AS2 inhibits breast cancer metastasis by regulating the miR-370-3p/FGF14 axis. Cell Death Discov. 6:1032020. View Article : Google Scholar : PubMed/NCBI | |
Fan C, Liu S, Zhao Y, Han Y, Yang L, Tao G, Li Q and Zhang L: Upregulation of miR-370 contributes to the progression of gastric carcinoma via suppression of FOXO1. Biomed Pharmacother. 67:521–526. 2013. View Article : Google Scholar : PubMed/NCBI | |
Lo SS, Hung PS, Chen JH, Tu HF, Fang WL, Chen CY, Chen WT, Gong NR and Wu CW: Overexpression of miR-370 and downregulation of its novel target TGFβ-RII contribute to the progression of gastric carcinoma. Oncogene. 31:226–237. 2012. View Article : Google Scholar : PubMed/NCBI | |
Ning T, Zhang H, Wang X, Li S, Zhang L, Deng T, Zhou L, Liu R, Wang X, Bai M, et al: miR-370 regulates cell proliferation and migration by targeting EGFR in gastric cancer. Oncol Rep. 38:384–392. 2017. View Article : Google Scholar : PubMed/NCBI | |
Pan X, Chen G and Hu W: lncRNA HLA complex group 18 (HCG18) facilitated cell proliferation, invasion, and migration of prostate cancer through modulating miR-370-3p/DDX3X axis. Reprod Sci. 28:3406–3416. 2021. View Article : Google Scholar : PubMed/NCBI | |
Wu Z, Sun H, Zeng W, He J and Mao X: Upregulation of MircoRNA-370 induces proliferation in human prostate cancer cells by downregulating the transcription factor FOXO1. PLoS One. 7:e458252012. View Article : Google Scholar : PubMed/NCBI | |
Xia S, Ji R and Zhan W: Long noncoding RNA papillary thyroid carcinoma susceptibility candidate 3 (PTCSC3) inhibits proliferation and invasion of glioma cells by suppressing the Wnt/β-catenin signaling pathway. BMC Neurol. 17:302017. View Article : Google Scholar : PubMed/NCBI | |
Klaus A and Birchmeier W: Wnt signalling and its impact on development and cancer. Nat Rev Cancer. 8:387–398. 2008. View Article : Google Scholar : PubMed/NCBI | |
Bauer A, Chauvet S, Huber O, Usseglio F, Rothbächer U, Aragnol D, Kemler R and Pradel J: Pontin52 and reptin52 function as antagonistic regulators of beta-catenin signalling activity. EMBO J. 19:6121–6130. 2000. View Article : Google Scholar : PubMed/NCBI | |
Zhang W, Duan N, Zhang Q, Song T, Li Z, Zhang C, Chen X and Wang K: DNA methylation mediated down-regulation of miR-370 regulates cell growth through activation of the Wnt/β-catenin signaling pathway in human osteosarcoma cells. Int J Biol Sci. 13:561–573. 2017. View Article : Google Scholar : PubMed/NCBI | |
Xu X, Zhang M, Xu F and Jiang S: Wnt signaling in breast cancer: Biological mechanisms, challenges and opportunities. Mol Cancer. 19:1652020. View Article : Google Scholar : PubMed/NCBI | |
Huang X, Zhu H, Gao Z, Li J, Zhuang J, Dong Y, Shen B, Li M, Zhou H, Guo H, et al: Wnt7a activates canonical Wnt signaling, promotes bladder cancer cell invasion, and is suppressed by miR-370-3p. J Biol Chem. 293:6693–6706. 2018. View Article : Google Scholar : PubMed/NCBI | |
Zhang R, Wang J, Jia E, Zhang J, Liu N and Chi C: lncRNA BCAR4 sponges miR-370-3p to promote bladder cancer progression via Wnt signaling. Int J Mol Med. 45:578–588. 2020.PubMed/NCBI | |
Asati V, Mahapatra DK and Bharti SK: PI3K/Akt/mTOR and Ras/Raf/MEK/ERK signaling pathways inhibitors as anticancer agents: Structural and pharmacological perspectives. Eur J Med Chem. 109:314–341. 2016. View Article : Google Scholar : PubMed/NCBI | |
Li G, Zheng P, Wang H, Ai Y and Mao X: Long Non-coding RNA TUG1 modulates proliferation, migration, and invasion of acute myeloid leukemia cells via regulating miR-370-3p/MAPK1/ERK. Onco Targets Ther. 12:10375–10388. 2019. View Article : Google Scholar : PubMed/NCBI | |
Aoki M and Fujishita T: Oncogenic roles of the PI3K/AKT/mTOR axis. Curr Top Microbiol Immunol. 7:153–189. 2017.PubMed/NCBI | |
Poma P: NF-κB and disease. Int J Mol Sci. 21:91812020. View Article : Google Scholar : PubMed/NCBI | |
Patel M, Horgan PG, McMillan DC and Edwards J: NF-κB pathways in the development and progression of colorectal cancer. Transl Res. 197:43–56. 2018. View Article : Google Scholar : PubMed/NCBI | |
Li R, Wu H, Jiang H, Wang Q, Dou Z, Ma H, Yan S, Yuan C, Yang N and Kong B: FBLN5 is targeted by microRNA-27a-3p and suppresses tumorigenesis and progression in high-grade serous ovarian carcinoma. Oncol Rep. 44:2143–2151. 2020.PubMed/NCBI | |
Matthews HK, Bertoli C and de Bruin RAM: Cell cycle control in cancer. Nat Rev Mol Cell Biol. 23:74–88. 2022. View Article : Google Scholar : PubMed/NCBI | |
Liu J, Peng Y and Wei W: Cell cycle on the crossroad of tumorigenesis and cancer therapy. Trends Cell Biol. 32:30–44. 2022. View Article : Google Scholar : PubMed/NCBI | |
Jiang X, Yang L, Gao Q, Liu Y, Feng X, Ye S and Yang Z: The role of RAB GTPases and its potential in predicting immunotherapy response and prognosis in colorectal cancer. Front Genet. 13:8283732022. View Article : Google Scholar : PubMed/NCBI | |
Guo M, Li S, Zhao X, Yuan Y, Zhang B and Guan Y: Knockdown of circular RNA Hsa_circ_0000714 can regulate RAB17 by sponging miR-370-3p to reduce paclitaxel resistance of ovarian cancer through CDK6/RB pathway. Onco Targets Ther. 13:13211–13224. 2020. View Article : Google Scholar : PubMed/NCBI | |
Takayama Y, Kamimura Y, Okawa M, Muramatsu S, Sugino A and Araki H: GINS, a novel multiprotein complex required for chromosomal DNA replication in budding yeast. Genes Dev. 17:1153–1165. 2003. View Article : Google Scholar : PubMed/NCBI | |
Yamane K, Naito H, Wakabayashi T, Yoshida H, Muramatsu F, Iba T, Kidoya H and Takakura N: Regulation of SLD5 gene expression by miR-370 during acute growth of cancer cells. Sci Rep. 6:309412016. View Article : Google Scholar : PubMed/NCBI | |
Wang Y, Lyu Z, Qin Y, Wang X, Sun L, Zhang Y, Gong L, Wu S, Han S, Tang Y, et al: FOXO1 promotes tumor progression by increased M2 macrophage infiltration in esophageal squamous cell carcinoma. Theranostics. 10:11535–11548. 2020. View Article : Google Scholar : PubMed/NCBI | |
Tang Y, Jiang L, Zhao X, Hu D, Zhao G, Luo S, Du X and Tang W: FOXO1 inhibits prostate cancer cell proliferation via suppressing E2F1 activated NPRL2 expression. Cell Biol Int. 45:2510–2520. 2021. View Article : Google Scholar : PubMed/NCBI | |
Yang H, Wen L, Wen M, Liu T, Zhao L, Wu B, Yun Y, Liu W, Wang H, Wang Y and Wen N: FoxM1 promotes epithelial-mesenchymal transition, invasion, and migration of tongue squamous cell carcinoma cells through a c-Met/AKT-dependent positive feedback loop. Anticancer Drugs. 29:216–226. 2018. View Article : Google Scholar : PubMed/NCBI | |
Zhang Y, Ye X, Chen L, Wu Q, Gao Y and Li Y: PARI functions as a new transcriptional target of FOXM1 involved in gastric cancer development. Int J Biol Sci. 14:531–541. 2018. View Article : Google Scholar : PubMed/NCBI | |
Narlik-Grassow M, Blanco-Aparicio C and Carnero A: The PIM family of serine/threonine kinases in cancer. Med Res Rev. 34:136–159. 2014. View Article : Google Scholar : PubMed/NCBI | |
Fang C, Wang X, Guo D, Fang R and Zhu T: Circular RNA CircITGA7 promotes tumorigenesis of osteosarcoma via miR-370/PIM1 axis. Comput Math Methods Med. 2020:13675762020. View Article : Google Scholar : PubMed/NCBI | |
Zou FW, Yang SZ, Li WY, Liu CY, Liu XH, Hu CH, Liu ZH and Xu S: circRNA_001275 upregulates Wnt7a expression by competitively sponging miR-370-3p to promote cisplatin resistance in esophageal cancer. Int J Oncol. 57:151–160. 2020. View Article : Google Scholar : PubMed/NCBI | |
Reiss K, Del Valle L, Lassak A and Trojanek J: Nuclear IRS-1 and cancer. J Cell Physiol. 27:2992–3000. 2012. View Article : Google Scholar : PubMed/NCBI | |
Li Q, Ye L, Zhang X, Wang M, Lin C, Huang S, Guo W, Lai Y, Du H, Li J, et al: FZD8, a target of p53, promotes bone metastasis in prostate cancer by activating canonical Wnt/β-catenin signaling. Cancer Lett. 402:166–176. 2017. View Article : Google Scholar : PubMed/NCBI | |
Wang N, Dong Q and Zhou XN: LMO4 promotes the invasion and proliferation of gastric cancer by activating PI3K-Akt-mTOR signaling. Am J Transl Res. 11:6534–6543. 2019.PubMed/NCBI | |
Xiong X, Feng Y, Li L, Yao J, Zhou M, Zhao P, Huang F, Zeng L and Yuan L: Long non-coding RNA SNHG1 promotes breast cancer progression by regulation of LMO4. Oncol Rep. 43:1503–1515. 2020.PubMed/NCBI | |
Liu L, Yan C, Tao S and Wang H: Circ_0058124 aggravates the progression of papillary thyroid carcinoma by activating LMO4 expression via targeting miR-370-3p. Cancer Manag Res. 12:9459–9470. 2020. View Article : Google Scholar : PubMed/NCBI | |
Wang B, Qi X, Liu J, Zhou R, Lin C, Shangguan J, Zhang Z, Zhao L and Li G: MYH9 promotes growth and metastasis via activation of MAPK/AKT signaling in colorectal cancer. J Cancer. 10:874–884. 2019. View Article : Google Scholar : PubMed/NCBI | |
Chen F, Yin S, Feng Z, Liu C, Lv J, Chen Y, Shen R, Wang J and Deng Z: Knockdown of circ_NEK6 decreased 131I resistance of differentiated thyroid carcinoma via regulating miR-370-3p/MYH9 axis. Technol Cancer Res Treat. 20:153303382110049502021. View Article : Google Scholar : PubMed/NCBI | |
Peng J, Chen XL, Cheng HZ, Xu ZY, Wang H, Shi ZZ, Liu J, Ning XG and Peng H: Silencing of KCNK15-AS1 inhibits lung cancer cell proliferation via upregulation of miR-202 and miR-370. Oncol Lett. 18:5968–5976. 2019.PubMed/NCBI | |
Luo Q, Lin H, Ye X, Huang J, Lu S and Xu L: Trim44 facilitates the migration and invasion of human lung cancer cells via the NF-κB signaling pathway. Int J Clin Oncol. 20:508–517. 2015. View Article : Google Scholar : PubMed/NCBI | |
Ma Q, Huai B, Liu Y, Jia Z and Zhao Q: Circular RNA circ_0020123 promotes non-small cell lung cancer progression through miR-384/TRIM44 axis. Cancer Manag Res. 13:75–87. 2021. View Article : Google Scholar : PubMed/NCBI | |
Wang X, Lv J, He B and Zhou D: CircFBXW8 acts an oncogenic role in the malignant progression of non-small cell lung carcinoma by miR-370-3p-dependent regulation of TRIM44. Biochem Genet. 60:1313–1332. 2022. View Article : Google Scholar : PubMed/NCBI | |
Ciardiello F and Tortora G: EGFR antagonists in cancer treatment. N Engl J Med. 358:1160–1174. 2008. View Article : Google Scholar : PubMed/NCBI | |
Li C, Zhang J, Zhou Y and Li B: Long non-coding RNA CASC9 promotes the progression and development of gastric cancer via regulating miR-370/EGFR axis. Dig Liver Dis. 53:509–516. 2021. View Article : Google Scholar : PubMed/NCBI | |
Lin L, Wang D, Qu S, Zhao H and Lin Y: miR-370-3p alleviates ulcerative Colitis-related colorectal cancer in mice through inhibiting the inflammatory response and epithelial-mesenchymal transition. Drug Des Devel Ther. 14:1127–1141. 2020. View Article : Google Scholar : PubMed/NCBI | |
Wu J, Lu G and Wang X: MDM4 alternative splicing and implication in MDM4 targeted cancer therapies. Am J Cancer Res. 11:5864–5880. 2021.PubMed/NCBI | |
Mo Y, Lu Q, Zhang Q, Chen J, Deng Y, Zhang K, Tao R, Liu W and Wang Y: Circular RNA CCDC66 improves murine double minute 4 (MDM4) expression through targeting miR-370 in colorectal cancer. Comput Math Methods Med. 2022:77239952022. View Article : Google Scholar : PubMed/NCBI | |
Kusakabe Y, Chiba T, Oshima M, Koide S, Rizq O, Aoyama K, Ao J, Kaneko T, Kanzaki H, Kanayama K, et al: EZH1/2 inhibition augments the anti-tumor effects of sorafenib in hepatocellular carcinoma. Sci Rep. 11:213962021. View Article : Google Scholar : PubMed/NCBI | |
Zhang Y, Li L, Lu XK, Yu LB, Meng J and Liu CY: LncRNA SNHG3 is responsible for the deterioration of colorectal carcinoma through regulating the miR-370-5p/EZH1 axis. Eur Rev Med Pharmacol Sci. 25:6131–6137. 2021.PubMed/NCBI | |
Liu Y, Ao X, Ding W, Ponnusamy M, Wu W, Hao X, Yu W, Wang Y, Li P and Wang J: Critical role of FoxO3a in carcinogenesis. Mol Cancer. 17:1042018. View Article : Google Scholar : PubMed/NCBI | |
Li C, Wang J, Zhang H, Zhu M, Chen F, Hu Y, Liu H and Zhu H: Interferon-stimulated gene 15 (ISG15) is a trigger for tumorigenesis and metastasis of hepatocellular carcinoma. Oncotarget. 5:8429–8441. 2014. View Article : Google Scholar : PubMed/NCBI | |
Riva V and Maga G: From the magic bullet to the magic target: Exploiting the diverse roles of DDX3X in viral infections and tumorigenesis. Future Med Chem. 11:1357–1381. 2019. View Article : Google Scholar : PubMed/NCBI | |
Xu Y, Zheng Y, Liu H and Li T: Modulation of IGF2BP1 by long non-coding RNA HCG11 suppresses apoptosis of hepatocellular carcinoma cells via MAPK signaling transduction. Int J Oncol. 51:791–800. 2017. View Article : Google Scholar : PubMed/NCBI | |
Wagner EF and Nebreda AR: Signal integration by JNK and p38 MAPK pathways in cancer development. Nat Rev Cancer. 9:537–549. 2009. View Article : Google Scholar : PubMed/NCBI | |
Yin X, Liu Z, Zhu P, Wang Y, Ren Q, Chen H and Xu J: CXCL12/CXCR4 promotes proliferation, migration, and invasion of adamantinomatous craniopharyngiomas via PI3K/AKT signal pathway. J Cell Biochem. 120:9724–9736. 2019. View Article : Google Scholar : PubMed/NCBI | |
Wei CY, Zhu MX, Lu NH, Liu JQ, Yang YW, Zhang Y, Shi YD, Feng ZH, Li JX, Qi FZ and Gu JY: Circular RNA circ_0020710 drives tumor progression and immune evasion by regulating the miR-370-3p/CXCL12 axis in melanoma. Mol Cancer. 19:842020. View Article : Google Scholar : PubMed/NCBI | |
Shang Y, Zhang F, Li D, Li C, Li H, Jiang Y and Zhang D: Overexpression of UQCRC2 is correlated with tumor progression and poor prognosis in colorectal cancer. Pathol Res Pract. 214:1613–1620. 2018. View Article : Google Scholar : PubMed/NCBI | |
Luo G, Li G, Wan Z, Zhang Y, Liu D and Guo Y: circITGA7 Acts as a miR-370-3p sponge to suppress the proliferation of prostate cancer. J Oncol. 2021:80603892021. View Article : Google Scholar : PubMed/NCBI | |
Saunier E, Benelli C and Bortoli S: The pyruvate dehydrogenase complex in cancer: An old metabolic gatekeeper regulated by new pathways and pharmacological agents. Int J Cancer. 138:809–817. 2016. View Article : Google Scholar : PubMed/NCBI | |
Parkin B, Ouillette P, Wang Y, Liu Y, Wright W, Roulston D, Purkayastha A, Dressel A, Karp J, Bockenstedt P, et al: NF1 inactivation in adult acute myelogenous leukemia. Clin Cancer Res. 16:4135–4147. 2010. View Article : Google Scholar : PubMed/NCBI | |
Xiao B, Chen D, Zhou Q, Hang J, Zhang W, Kuang Z, Sun Z and Li L: Glutamate metabotropic receptor 4 (GRM4) inhibits cell proliferation, migration and invasion in breast cancer and is regulated by miR-328-3p and miR-370-3p. BMC Cancer. 19:8912019. View Article : Google Scholar : PubMed/NCBI | |
Bera K, Kiepas A, Godet I, Li Y, Mehta P, Ifemembi B, Paul CD, Sen A, Serra SA, Stoletov K, et al: Extracellular fluid viscosity enhances cell migration and cancer dissemination. Nature. 611:365–373. 2022. View Article : Google Scholar : PubMed/NCBI | |
Su T, Huang L, Zhang N, Peng S, Li X, Wei G, Zhai E, Zeng Z and Xu L: FGF14 Functions as a Tumor Suppressor through Inhibiting PI3K/AKT/mTOR Pathway in Colorectal Cancer. J Cancer. 11:819–825. 2020. View Article : Google Scholar : PubMed/NCBI | |
Komuro A, Yashiro M, Iwata C, Morishita Y, Johansson E, Matsumoto Y, Watanabe A, Aburatani H, Miyoshi H, Kiyono K, et al: Diffuse-type gastric carcinoma: Progression, angiogenesis, and transforming growth factor beta signaling. J Natl Cancer Inst. 101:592–604. 2009. View Article : Google Scholar : PubMed/NCBI | |
Nassar D and Blanpain C: Cancer stem cells: Basic concepts and therapeutic implications. Annu Rev Pathol. 11:47–76. 2016. View Article : Google Scholar : PubMed/NCBI | |
Walcher L, Kistenmacher AK, Suo H, Kitte R, Dluczek S, Strauß A, Blaudszun AR, Yevsa T, Fricke S and Kossatz-Boehlert U: Cancer stem cells-origins and biomarkers: Perspectives for targeted personalized therapies. Front Immunol. 11:12802020. View Article : Google Scholar : PubMed/NCBI | |
Kaltschmidt C, Banz-Jansen C, Benhidjeb T, Beshay M, Förster C, Greiner J, Hamelmann E, Jorch N, Mertzlufft F, Pfitzenmaier J, et al: A role for NF-κB in organ specific cancer and cancer stem cells. Cancers (Basel). 11:6552019. View Article : Google Scholar : PubMed/NCBI | |
Liu AM, Zhu Y, Huang ZW, Lei L, Fu SZ and Chen Y: Long noncoding RNA FAM201A involves in radioresistance of non-small-cell lung cancer by enhancing EGFR expression via miR-370. Eur Rev Med Pharmacol Sci. 23:5802–5814. 2019.PubMed/NCBI | |
Wang K, Zhu G, Bao S and Chen S: Long non-coding RNA LINC00511 mediates the effects of ESR1 on proliferation and invasion of ovarian cancer through miR-424-5p and miR-370-5p. Cancer Manag Res. 11:10807–10819. 2019. View Article : Google Scholar : PubMed/NCBI | |
Endo M, Tanaka Y, Otsuka M and Minami Y: E2F1-Ror2 signaling mediates coordinated transcriptional regulation to promote G1/S phase transition in bFGF-stimulated NIH/3T3 fibroblasts. FASEB J. 34:3413–3428. 2020. View Article : Google Scholar : PubMed/NCBI | |
Zeng B, Li Z, Chen R, Guo N, Zhou J, Zhou Q, Lin Q, Cheng D, Liao Q, Zheng L and Gong Y: Epigenetic regulation of miR-124 by hepatitis C virus core protein promotes migration and invasion of intrahepatic cholangiocarcinoma cells by targeting SMYD3. FEBS Lett. 586:3271–3278. 2012. View Article : Google Scholar : PubMed/NCBI | |
Pan X, Wang H, Tong D, Wang C, Sun L, Zhao C, Li Y, Zhu L and Wu D: Physcion induces apoptosis in hepatocellular carcinoma by modulating miR-370. Am J Cancer Res. 6:2919–2931. 2016.PubMed/NCBI | |
Kuete V, Mbaveng AT, Nono EC, Simo CC, Zeino M, Nkengfack AE and Efferth T: Cytotoxicity of seven naturally occurring phenolic compounds towards multi-factorial drug-resistant cancer cells. Phytomedicine. 23:856–863. 2016. View Article : Google Scholar : PubMed/NCBI | |
Ye LH, Ma X and Xu SC: Expression and clinical significance of serum MiR-370 and MiR-203 in patients with acute myeloid leukemia. Zhongguo Shi Yan Xue Ye Xue Za Zhi. 29:445–449. 2021.(In Chinese). PubMed/NCBI | |
Bautista-Sánchez D, Arriaga-Canon C, Pedroza-Torres A, De La Rosa-Velázquez IA, González-Barrios R, Contreras-Espinosa L, Montiel-Manríquez R, Castro-Hernández C, Fragoso-Ontiveros V, Álvarez-Gómez RM and Herrera LA: The Promising role of miR-21 as a cancer biomarker and its importance in RNA-based therapeutics. Mol Ther Nucleic Acids. 20:409–420. 2020. View Article : Google Scholar : PubMed/NCBI | |
Pan XP, Huang LH and Wang X: MiR-370 functions as prognostic marker in patients with hepatocellular carcinoma. Eur Rev Med Pharmacol Sci. 21:3581–3585. 2017.PubMed/NCBI |