Open Access

Recent findings on miR‑370 expression, regulation and functions in cancer (Review)

  • Authors:
    • Lingling Ye
    • Jinqiu Wang
    • Kui Yi
    • Fen Wang
    • Jinyan Wang
    • Hao Wu
    • Hui Yang
    • Zhaohui Yang
    • Quan'an Zhang
  • View Affiliations

  • Published online on: March 3, 2023     https://doi.org/10.3892/or.2023.8516
  • Article Number: 79
  • Copyright: © Ye et al. This is an open access article distributed under the terms of Creative Commons Attribution License.

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Abstract

MicroRNAs (miRNAs/miRs) are a group of small non‑coding RNAs that serve as post‑transcriptional gene modulators. miRNAs have been demonstrated to serve a pivotal role in carcinogenesis and the dysregulated expression of miRNAs is a well‑understood characteristic of cancer. In recent years, miR‑370 has been established as a key miRNA in various cancers. The expression of miR‑370 is dysregulated in various types of cancer and varies markedly across different tumor types. miR‑370 can regulate multiple biological processes, including cell proliferation, apoptosis, migration, invasion, as well as cell cycle progression and cell stemness. Moreover, it has been reported that miR‑370 affects the response of tumor cells to anticancer treatments. Additionally, the expression of miR‑370 is modulated by multiple factors. The present review summarizes the role and mechanism of miR‑370 in tumors, and demonstrates its potential as a molecular marker for cancer diagnosis and prognosis.
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April-2023
Volume 49 Issue 4

Print ISSN: 1021-335X
Online ISSN:1791-2431

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Copy and paste a formatted citation
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Spandidos Publications style
Ye L, Wang J, Yi K, Wang F, Wang J, Wu H, Yang H, Yang Z and Zhang Q: Recent findings on miR‑370 expression, regulation and functions in cancer (Review). Oncol Rep 49: 79, 2023
APA
Ye, L., Wang, J., Yi, K., Wang, F., Wang, J., Wu, H. ... Zhang, Q. (2023). Recent findings on miR‑370 expression, regulation and functions in cancer (Review). Oncology Reports, 49, 79. https://doi.org/10.3892/or.2023.8516
MLA
Ye, L., Wang, J., Yi, K., Wang, F., Wang, J., Wu, H., Yang, H., Yang, Z., Zhang, Q."Recent findings on miR‑370 expression, regulation and functions in cancer (Review)". Oncology Reports 49.4 (2023): 79.
Chicago
Ye, L., Wang, J., Yi, K., Wang, F., Wang, J., Wu, H., Yang, H., Yang, Z., Zhang, Q."Recent findings on miR‑370 expression, regulation and functions in cancer (Review)". Oncology Reports 49, no. 4 (2023): 79. https://doi.org/10.3892/or.2023.8516