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Heterogeneity and individualized treatment of microenvironment in glioblastoma (Review)

  • Authors:
    • Wei Kang
    • Zhixiao Mo
    • Wenshan Li
    • Haifeng Ma
    • Qiang Zhang
  • View Affiliations / Copyright

    Affiliations: Department of Neurosurgery, Qinghai Provincial People's Hospital, Xining, Qinghai 810001, P.R. China, Department of Neurosurgery, Qinghai Cardio‑Cerebrovascular Hospital, Xining, Qinghai 810099, P.R. China
    Copyright: © Kang et al. This is an open access article distributed under the terms of Creative Commons Attribution License.
  • Article Number: 217
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    Published online on: October 25, 2023
       https://doi.org/10.3892/or.2023.8654
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Abstract

The heterogeneity of glioblastoma can suppress immune cell function and lead to immune evasion, which presents a challenge in developing effective molecular therapies for tumor cells. However, the study of tumor immune heterogeneity holds great potential for clinical immunotherapy. Liquid biopsy is a useful tool for accurately monitoring dynamic changes in tumor immune heterogeneity and the tumor microenvironment. This paper explores the heterogeneity of glioblastoma and the immune microenvironment, providing a therapeutic basis for individualized treatment. Using liquid biopsy technology as a new diagnostic method, innovative treatment strategies may be implemented for patients with glioblastoma to improve their outcomes.
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Copy and paste a formatted citation
Spandidos Publications style
Kang W, Mo Z, Li W, Ma H and Zhang Q: Heterogeneity and individualized treatment of microenvironment in glioblastoma (Review). Oncol Rep 50: 217, 2023.
APA
Kang, W., Mo, Z., Li, W., Ma, H., & Zhang, Q. (2023). Heterogeneity and individualized treatment of microenvironment in glioblastoma (Review). Oncology Reports, 50, 217. https://doi.org/10.3892/or.2023.8654
MLA
Kang, W., Mo, Z., Li, W., Ma, H., Zhang, Q."Heterogeneity and individualized treatment of microenvironment in glioblastoma (Review)". Oncology Reports 50.6 (2023): 217.
Chicago
Kang, W., Mo, Z., Li, W., Ma, H., Zhang, Q."Heterogeneity and individualized treatment of microenvironment in glioblastoma (Review)". Oncology Reports 50, no. 6 (2023): 217. https://doi.org/10.3892/or.2023.8654
Copy and paste a formatted citation
x
Spandidos Publications style
Kang W, Mo Z, Li W, Ma H and Zhang Q: Heterogeneity and individualized treatment of microenvironment in glioblastoma (Review). Oncol Rep 50: 217, 2023.
APA
Kang, W., Mo, Z., Li, W., Ma, H., & Zhang, Q. (2023). Heterogeneity and individualized treatment of microenvironment in glioblastoma (Review). Oncology Reports, 50, 217. https://doi.org/10.3892/or.2023.8654
MLA
Kang, W., Mo, Z., Li, W., Ma, H., Zhang, Q."Heterogeneity and individualized treatment of microenvironment in glioblastoma (Review)". Oncology Reports 50.6 (2023): 217.
Chicago
Kang, W., Mo, Z., Li, W., Ma, H., Zhang, Q."Heterogeneity and individualized treatment of microenvironment in glioblastoma (Review)". Oncology Reports 50, no. 6 (2023): 217. https://doi.org/10.3892/or.2023.8654
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