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Exosomal circRNAs in gastrointestinal cancer: Role in occurrence, development, diagnosis and clinical application (Review)

  • Authors:
    • Yumeng Xu
    • Jiayi Han
    • Xuan Zhang
    • Xinyi Zhang
    • Jiajia Song
    • Zihan Gao
    • Hui Qian
    • Jianhua Jin
    • Zhaofeng Liang
  • View Affiliations / Copyright

    Affiliations: Wujin Institute of Molecular Diagnostics and Precision Cancer Medicine of Jiangsu University, Wujin Hospital Affiliated with Jiangsu University, Changzhou, Jiangsu 213017, P.R. China, Jiangsu Key Laboratory of Medical Science and Laboratory Medicine, School of Medicine, Jiangsu University, Zhenjiang, Jiangsu 212013, P.R. China
    Copyright: © Xu et al. This is an open access article distributed under the terms of Creative Commons Attribution License.
  • Article Number: 19
    |
    Published online on: December 8, 2023
       https://doi.org/10.3892/or.2023.8678
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Abstract

Gastrointestinal cancer is frequently detected at an advanced stage and has an undesirable prognosis due to the absence of efficient and precise biomarkers and therapeutic targets. Exosomes are small, living‑cell‑derived vesicles that serve a critical role in facilitating intercellular communication by transporting molecules from donor cells to receiver cells. circular RNAs (circRNAs) are mis‑expressed in a variety of diseases, including gastrointestinal cancer, and are promising as diagnostic biomarkers and tumor therapeutic targets for gastrointestinal cancer. The main features of exosomes and circRNAs are discussed in the present review, along with research on the biological function of exosomal circRNAs in the development and progression of gastrointestinal cancer. It also assesses the advantages and disadvantages of implementing these findings in clinical applications.
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Copy and paste a formatted citation
Spandidos Publications style
Xu Y, Han J, Zhang X, Zhang X, Song J, Gao Z, Qian H, Jin J and Liang Z: Exosomal circRNAs in gastrointestinal cancer: Role in occurrence, development, diagnosis and clinical application (Review). Oncol Rep 51: 19, 2024.
APA
Xu, Y., Han, J., Zhang, X., Zhang, X., Song, J., Gao, Z. ... Liang, Z. (2024). Exosomal circRNAs in gastrointestinal cancer: Role in occurrence, development, diagnosis and clinical application (Review). Oncology Reports, 51, 19. https://doi.org/10.3892/or.2023.8678
MLA
Xu, Y., Han, J., Zhang, X., Zhang, X., Song, J., Gao, Z., Qian, H., Jin, J., Liang, Z."Exosomal circRNAs in gastrointestinal cancer: Role in occurrence, development, diagnosis and clinical application (Review)". Oncology Reports 51.2 (2024): 19.
Chicago
Xu, Y., Han, J., Zhang, X., Zhang, X., Song, J., Gao, Z., Qian, H., Jin, J., Liang, Z."Exosomal circRNAs in gastrointestinal cancer: Role in occurrence, development, diagnosis and clinical application (Review)". Oncology Reports 51, no. 2 (2024): 19. https://doi.org/10.3892/or.2023.8678
Copy and paste a formatted citation
x
Spandidos Publications style
Xu Y, Han J, Zhang X, Zhang X, Song J, Gao Z, Qian H, Jin J and Liang Z: Exosomal circRNAs in gastrointestinal cancer: Role in occurrence, development, diagnosis and clinical application (Review). Oncol Rep 51: 19, 2024.
APA
Xu, Y., Han, J., Zhang, X., Zhang, X., Song, J., Gao, Z. ... Liang, Z. (2024). Exosomal circRNAs in gastrointestinal cancer: Role in occurrence, development, diagnosis and clinical application (Review). Oncology Reports, 51, 19. https://doi.org/10.3892/or.2023.8678
MLA
Xu, Y., Han, J., Zhang, X., Zhang, X., Song, J., Gao, Z., Qian, H., Jin, J., Liang, Z."Exosomal circRNAs in gastrointestinal cancer: Role in occurrence, development, diagnosis and clinical application (Review)". Oncology Reports 51.2 (2024): 19.
Chicago
Xu, Y., Han, J., Zhang, X., Zhang, X., Song, J., Gao, Z., Qian, H., Jin, J., Liang, Z."Exosomal circRNAs in gastrointestinal cancer: Role in occurrence, development, diagnosis and clinical application (Review)". Oncology Reports 51, no. 2 (2024): 19. https://doi.org/10.3892/or.2023.8678
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