Spandidos Publications Logo
  • About
    • About Spandidos
    • Aims and Scopes
    • Abstracting and Indexing
    • Editorial Policies
    • Reprints and Permissions
    • Job Opportunities
    • Terms and Conditions
    • Contact
  • Journals
    • All Journals
    • Oncology Letters
      • Oncology Letters
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Oncology
      • International Journal of Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular and Clinical Oncology
      • Molecular and Clinical Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Experimental and Therapeutic Medicine
      • Experimental and Therapeutic Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Molecular Medicine
      • International Journal of Molecular Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Biomedical Reports
      • Biomedical Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Reports
      • Oncology Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular Medicine Reports
      • Molecular Medicine Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • World Academy of Sciences Journal
      • World Academy of Sciences Journal
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Functional Nutrition
      • International Journal of Functional Nutrition
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Epigenetics
      • International Journal of Epigenetics
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Medicine International
      • Medicine International
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
  • Articles
  • Information
    • Information for Authors
    • Information for Reviewers
    • Information for Librarians
    • Information for Advertisers
    • Conferences
  • Language Editing
Spandidos Publications Logo
  • About
    • About Spandidos
    • Aims and Scopes
    • Abstracting and Indexing
    • Editorial Policies
    • Reprints and Permissions
    • Job Opportunities
    • Terms and Conditions
    • Contact
  • Journals
    • All Journals
    • Biomedical Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Experimental and Therapeutic Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Epigenetics
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Functional Nutrition
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Molecular Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Medicine International
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular and Clinical Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular Medicine Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Letters
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • World Academy of Sciences Journal
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
  • Articles
  • Information
    • For Authors
    • For Reviewers
    • For Librarians
    • For Advertisers
    • Conferences
  • Language Editing
Login Register Submit
  • This site uses cookies
  • You can change your cookie settings at any time by following the instructions in our Cookie Policy. To find out more, you may read our Privacy Policy.

    I agree
Search articles by DOI, keyword, author or affiliation
Search
Advanced Search
presentation
Oncology Reports
Join Editorial Board Propose a Special Issue
Print ISSN: 1021-335X Online ISSN: 1791-2431
Journal Cover
March-2024 Volume 51 Issue 3

Full Size Image

Sign up for eToc alerts
Recommend to Library

Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

Journal Cover
March-2024 Volume 51 Issue 3

Full Size Image

Sign up for eToc alerts
Recommend to Library

  • Article
  • Citations
    • Cite This Article
    • Download Citation
    • Create Citation Alert
    • Remove Citation Alert
    • Cited By
  • Similar Articles
    • Related Articles (in Spandidos Publications)
    • Similar Articles (Google Scholar)
    • Similar Articles (PubMed)
  • Download PDF
  • Download XML
  • View XML
Review

Advances in research and application of photodynamic therapy in cholangiocarcinoma (Review)

  • Authors:
    • Yufeng Li
    • Yuhang Li
    • Yinghui Song
    • Sulai Liu
  • View Affiliations / Copyright

    Affiliations: Department of Hepatobiliary Surgery, The First Affiliated Hospital of Hunan Normal University, Changsha, Hunan 410005, P.R. China, Central Laboratory of Hunan Provincial People's Hospital (The First Affiliated Hospital of Hunan Normal University), Changsha, Hunan 410005, P.R. China
  • Article Number: 53
    |
    Published online on: February 2, 2024
       https://doi.org/10.3892/or.2024.8712
  • Expand metrics +
Metrics: Total Views: 0 (Spandidos Publications: | PMC Statistics: )
Metrics: Total PDF Downloads: 0 (Spandidos Publications: | PMC Statistics: )
Cited By (CrossRef): 0 citations Loading Articles...

This article is mentioned in:



Abstract

Cholangiocarcinoma (CCA) is a disease characterized by insidious clinical manifestations and challenging to diagnose. Patients are usually diagnosed at an advanced stage and miss the opportunity for radical surgery. Therefore, effective palliative therapy is the main treatment approach for unresectable CCA. Current common palliative treatments include biliary drainage, chemotherapy, radiotherapy, targeted therapy and immunotherapy. However, these treatments only offer limited improvement in quality of life and survival. Photodynamic therapy (PDT) is a novel local treatment method that is considered a safe tumor ablation method for numerous cancers. It has shown good efficacy in various studies of CCA and is expected to become an important treatment for CCA. In the present study, the mechanisms of PDT in the treatment of CCA were systematically explored and the progress in the research of photosensitizers was discussed. The current study focused on the various PDT protocols and their therapeutic effects in CCA, with the objective of providing a new horizon for future research and clinical applications of PDT in the treatment of CCA.
View Figures

Figure 1

View References

1 

Rizvi S, Khan SA, Hallemeier CL, Kelley RK and Gores GJ: Cholangiocarcinoma-evolving concepts and therapeutic strategies. Nat Rev Clin Oncol. 15:95–111. 2018. View Article : Google Scholar : PubMed/NCBI

2 

Song Y, Cai M, Li Y and Liu S: The focus clinical research in intrahepatic cholangiocarcinoma. Eur J Med Res. 27:1162022. View Article : Google Scholar : PubMed/NCBI

3 

Banales JM, Marin JJG, Lamarca A, Rodrigues PM, Khan SA, Roberts LR, Cardinale V, Carpino G, Andersen JB, Braconi C, et al: Cholangiocarcinoma 2020: The next horizon in mechanisms and management. Nat Rev Gastroenterol Hepatol. 17:557–588. 2020. View Article : Google Scholar : PubMed/NCBI

4 

Everhart JE and Ruhl CE: Burden of digestive diseases in the United States part III: Liver, biliary tract, and pancreas. Gastroenterology. 136:1134–1144. 2009. View Article : Google Scholar : PubMed/NCBI

5 

Khan SA, Davidson BR, Goldin RD, Heaton N, Karani J, Pereira SP, Rosenberg WM, Tait P, Taylor-Robinson SD, Thillainayagam AV, et al: Guidelines for the diagnosis and treatment of cholangiocarcinoma: An update. Gut. 61:1657–1669. 2012. View Article : Google Scholar : PubMed/NCBI

6 

Li Y, Song Y and Liu S: The new insight of treatment in Cholangiocarcinoma. J Cancer. 13:450–464. 2022. View Article : Google Scholar : PubMed/NCBI

7 

Valero V III, Cosgrove D, Herman JM and Pawlik TM: Management of perihilar cholangiocarcinoma in the era of multimodal therapy. Expert Rev Gastroenterol Hepatol. 6:481–495. 2012. View Article : Google Scholar : PubMed/NCBI

8 

Glazer ES, Liu P, Abdalla EK, Vauthey JN and Curley SA: Neither neoadjuvant nor adjuvant therapy increases survival after biliary tract cancer resection with wide negative margins. J Gastrointest Surg. 16:1666–16671. 2012. View Article : Google Scholar : PubMed/NCBI

9 

Valle J, Wasan H, Palmer DH, Cunningham D, Anthoney A, Maraveyas A, Madhusudan S, Iveson T, Hughes S, Pereira SP, et al: Cisplatin plus gemcitabine versus gemcitabine for biliary tract cancer. N Engl J Med. 362:1273–1281. 2010. View Article : Google Scholar : PubMed/NCBI

10 

Dolmans DE, Fukumura D and Jain RK: Photodynamic therapy for cancer. Nat Rev Cancer. 3:380–387. 2003. View Article : Google Scholar : PubMed/NCBI

11 

McCaughan JS Jr, Mertens BF, Cho C, Barabash RD and Payton HW: Photodynamic therapy to treat tumors of the extrahepatic biliary ducts. A case report. Arch Surg. 126:111–113. 1991. View Article : Google Scholar : PubMed/NCBI

12 

Rerknimitr R, Angsuwatcharakon P, Ratanachu-ek T, Khor CJ, Ponnudurai R, Moon JH, Seo DW, Pantongrag-Brown L, Sangchan A, Pisespongsa P, et al: Asia-Pacific consensus recommendations for endoscopic and interventional management of hilar cholangiocarcinoma. J Gastroenterol Hepatol. 28:593–607. 2013. View Article : Google Scholar : PubMed/NCBI

13 

Agostinis P, Berg K, Cengel KA, Foster TH, Girotti AW, Gollnick SO, Hahn SM, Hamblin MR, Juzeniene A, Kessel D, et al: Photodynamic therapy of cancer: An update. CA Cancer J Clin. 61:250–281. 2011. View Article : Google Scholar : PubMed/NCBI

14 

Baptista MS, Cadet J, Di Mascio P, Ghogare AA, Greer A, Hamblin MR, Lorente C, Nunez SC, Ribeiro MS, Thomas AH, et al: Type I and type II guidelines and mechanistic pathways. Photochem Photobiol. 93:912–919. 2017. View Article : Google Scholar : PubMed/NCBI

15 

Castano AP, Mroz P and Hamblin MR: Photodynamic therapy and anti-tumour immunity. Nat Rev Cancer. 6:535–545. 2006. View Article : Google Scholar : PubMed/NCBI

16 

Chen B, Roskams T and de Witte PA: Antivascular tumor eradication by hypericin-mediated photodynamic therapy. Photochem Photobiol. 76:509–513. 2002. View Article : Google Scholar : PubMed/NCBI

17 

Maharjan PS and Bhattarai HK: Singlet oxygen, photodynamic therapy, and mechanisms of cancer cell death. J Oncol. 2022:72114852022. View Article : Google Scholar : PubMed/NCBI

18 

Brown SB, Brown EA and Walker I: The present and future role of photodynamic therapy in cancer treatment. Lancet Oncol. 5:497–508. 2004. View Article : Google Scholar : PubMed/NCBI

19 

Yanovsky RL, Bartenstein DW, Rogers GS, Isakoff SJ and Chen ST: Photodynamic therapy for solid tumors: A review of the literature. Photodermatol Photoimmunol Photomed. 35:295–303. 2004. View Article : Google Scholar : PubMed/NCBI

20 

Lucky SS, Soo KC and Zhang Y: Nanoparticles in photodynamic therapy. Chem Rev. 115:1990–2042. 2015. View Article : Google Scholar : PubMed/NCBI

21 

Fan W, Huang and Chen X: Overcoming the Achilles' heel of photodynamic therapy. Chem Soc Rev. 45:6488–6519. 2016. View Article : Google Scholar : PubMed/NCBI

22 

Hu F, Xu S and Liu B: Photosensitizers with aggregation-induced emission: Materials and biomedical applications. Adv Mater. 30:e18013502018. View Article : Google Scholar : PubMed/NCBI

23 

Mroz P, Yaroslavsky A, Kharkwal GB and Hamblin MR: Cell death pathways in photodynamic therapy of cancer. Cancers (Basel). 3:2516–2539. 2011. View Article : Google Scholar : PubMed/NCBI

24 

Zhang J, Jiang C, Longo JP, Azevedo RB, Zhang H and Muehlmann LA: An updated overview on the development of new photosensitizers for anticancer photodynamic therapy. Acta Pharm Sin B. 8:137–146. 2018. View Article : Google Scholar : PubMed/NCBI

25 

Kniebuhler G, Pongratz T, Betz CS, Göke B, Sroka R, Stepp H and Schirra J: Photodynamic therapy for cholangiocarcinoma using low dose mTHPC (Foscan(®)). Photodiagnosis Photodyn Ther. 10:220–228. 2013. View Article : Google Scholar : PubMed/NCBI

26 

Wagner A, Denzer UW, Neureiter D, Kiesslich T, Puespoeck A, Rauws EA, Emmanuel K, Degenhardt N, Frick U, Beuers U, et al: Temoporfin improves efficacy of photodynamic therapy in advanced biliary tract carcinoma: A multicenter prospective phase II study. Hepatology. 62:1456–1465. 2015. View Article : Google Scholar : PubMed/NCBI

27 

Mattioli EJ, Ulfo L, Marconi A, Pellicioni V, Costantini PE, Marforio TD, Di Giosia M, Danielli A, Fimognari C, Turrini E and Calvaresi M: Carrying temoporfin with human serum albumin: A new perspective for photodynamic application in head and neck cancer. Biomolecules. 13:682022. View Article : Google Scholar : PubMed/NCBI

28 

Chen K, Yin B, Luo Q, Liu Y, Wang Y, Liao Y, Li Y, Chen X, Sun B, Zhou N, et al: Endoscopically guided interventional photodynamic therapy for orthotopic pancreatic ductal adenocarcinoma based on NIR-II fluorescent nanoparticles. Theranostics. 13:4469–4481. 2023. View Article : Google Scholar : PubMed/NCBI

29 

Stein NC, Mulac D, Fabian J, Herrmann FC and Langer K: Nanoparticle albumin-bound mTHPC for photodynamic therapy: Preparation and comprehensive characterization of a promising drug delivery system. Int J Pharm. 582:1193472020. View Article : Google Scholar : PubMed/NCBI

30 

Grunebaum J, Söbbing J, Mulac D and Langer K: Nanoparticulate carriers for photodynamic therapy of cholangiocarcinoma: In vitro comparison of various polymer-based nanoparticles. Int J Pharm. 496:942–952. 2015. View Article : Google Scholar : PubMed/NCBI

31 

Kurokawa H, Ito H and Matsui H: Porphylipoprotein accumulation and porphylipoprotein photodynamic therapy effects involving cancer cell-specific cytotoxicity. Int J Mol Sci. 22:73062021. View Article : Google Scholar : PubMed/NCBI

32 

Dias LM, de Keijzer MJ, Ernst D, Sharifi F, de Klerk DJ, Kleijn TG, Desclos E, Kochan JA, de Haan LR, Franchi LP, et al: Metallated phthalocyanines and their hydrophilic derivatives for multi-targeted oncological photodynamic therapy. J Photochem Photobiol B. 234:1125002022. View Article : Google Scholar : PubMed/NCBI

33 

Zheng B, Zhong D, Xi T, Zhou J, Li W, Ilya A, Lu Y, Zhou M and Deng R: Near-infrared photosensitization via direct triplet energy transfer from lanthanide nanoparticles. Chem. 7:1615–1625. 2021. View Article : Google Scholar

34 

Lu K, He C and Lin W: Nanoscale metal-organic framework for highly effective photodynamic therapy of resistant head and neck cancer. J Am Chem Soc. 136:16712–1675. 2014. View Article : Google Scholar : PubMed/NCBI

35 

Alves SR, Calori IR and Tedesco AC: Photosensitizer-based metal-organic frameworks for highly effective photodynamic therapy. Mater Sci Eng C Mater Biol Appl. 131:1125142021. View Article : Google Scholar : PubMed/NCBI

36 

Oleinick NL and Evans HH: The photobiology of photodynamic therapy: Cellular targets and mechanisms. Radiat Res. 150 (5 Suppl):S146–S156. 1998. View Article : Google Scholar : PubMed/NCBI

37 

Agarwal ML, Clay ME, Harvey EJ, Evans HH, Antunez AR and Oleinick NL: Photodynamic therapy induces rapid cell death by apoptosis in L5178Y mouse lymphoma cells. Cancer Res. 51:5993–5996. 1991.PubMed/NCBI

38 

He JL, Guo MT, Tang L, Li B, Ma T and Cao Z: Multifunctional DNA nanosphere platform for real-time monitoring and fluorescence imaging-guided photodynamic therapy. Sensors and Actuators B: Chemical. 399:1347192024. View Article : Google Scholar : PubMed/NCBI

39 

Buytaert E, Dewaele M and Agostinis P: Molecular effectors of multiple cell death pathways initiated by photodynamic therapy. Biochim Biophys Acta. 1776:86–107. 2007.PubMed/NCBI

40 

Ortel B, Shea CR and Calzavara-Pinton P: Molecular mechanisms of photodynamic therapy. Front Biosci (Landmark Ed). 14:4157–4172. 2009. View Article : Google Scholar : PubMed/NCBI

41 

He C, Xia J, Gao Y, Chen Z and Wan X: Chlorin A-mediated photodynamic therapy induced apoptosis in human cholangiocarcinoma cells via impaired autophagy flux. Am J Transl Res. 12:5080–5094. 2020.PubMed/NCBI

42 

Casini A, Leone S, Vaccaro R, Vivacqua G, Ceci L, Pannarale L, Franchitto A, Onori P, Gaudio E and Mancinelli R: The emerging role of ferroptosis in liver cancers. Life (Basel). 12:21282022.PubMed/NCBI

43 

Zhang ZJ, Huang YP, Li XX, Liu ZT, Liu K, Deng XF, Xiong L, Zou H and Wen Y: A novel ferroptosis-related 4-gene prognostic signature for cholangiocarcinoma and photodynamic therapy. Front Oncol. 11:7474452021. View Article : Google Scholar : PubMed/NCBI

44 

Preise D, Scherz A and Salomon Y: Antitumor immunity promoted by vascular occluding therapy: Lessons from vascular-targeted photodynamic therapy (VTP). Photochem Photobiol Sci. 10:681–688. 2011. View Article : Google Scholar : PubMed/NCBI

45 

Chen B, Crane C, He C, Gondek D, Agharkar P, Savellano MD, Hoopes PJ and Pogue BW: Disparity between prostate tumor interior versus peripheral vasculature in response to verteporfin-mediated vascular-targeting therapy. Int J Cancer. 123:695–701. 2008. View Article : Google Scholar : PubMed/NCBI

46 

Liu Y, Deng F, Zheng R, Chen X, Zhao L, Yu B, Chen A, Jiang X, Cheng H and Li S: Self-delivery nanomedicine for vascular disruption-supplemented chemo-photodynamic tumor therapy. J Colloid Interface Sci. 612:562–571. 2022. View Article : Google Scholar : PubMed/NCBI

47 

Zhou J, Wang G, Chen Y, Wang H, Hua Y and Cai Z: Immunogenic cell death in cancer therapy: Present and emerging inducers. J Cell Mol Med. 23:4854–4865. 2019. View Article : Google Scholar : PubMed/NCBI

48 

Correia JH, Rodrigues JA, Pimenta S, Dong T and Yang Z: Photodynamic therapy review: Principles, photosensitizers, applications, and future directions. Pharmaceutics. 13:13322021. View Article : Google Scholar : PubMed/NCBI

49 

Li W, Yang J, Luo L, Jiang M, Qin B, Yin H, Zhu C, Yuan X, Zhang J, Luo Z, et al: Targeting photodynamic and photothermal therapy to the endoplasmic reticulum enhances immunogenic cancer cell death. Nat Commun. 10:33492019. View Article : Google Scholar : PubMed/NCBI

50 

Liao S, Wang Y, Li Z, Zhang Y, Yin X, Huan S, Zhang XB, Liu S and Song G: A novel afterglow nanoreporter for monitoring cancer therapy. Theranostics. 12:6883–6897. 2022. View Article : Google Scholar : PubMed/NCBI

51 

Ji B, Wei M and Yang B: Recent advances in nanomedicines for photodynamic therapy (PDT)-driven cancer immunotherapy. Theranostics. 12:434–458. 2022. View Article : Google Scholar : PubMed/NCBI

52 

Mansour JC, Aloia TA, Crane CH, Heimbach JK, Nagino M and Vauthey JN: Hilar cholangiocarcinoma: Expert consensus statement. HPB (Oxford). 17:691–699. 2015. View Article : Google Scholar : PubMed/NCBI

53 

Witzigmann H, Berr F, Ringel U, Caca K, Uhlmann D, Schoppmeyer K, Tannapfel A, Wittekind C, Mossner J, Hauss J and Wiedmann M: Surgical and palliative management and outcome in 184 patients with hilar cholangiocarcinoma: Palliative photodynamic therapy plus stenting is comparable to r1/r2 resection. Ann Surg. 244:230–239. 2006. View Article : Google Scholar : PubMed/NCBI

54 

Zoepf T, Jakobs R, Arnold JC, Apel D and Riemann JF: Palliation of nonresectable bile duct cancer: Improved survival after photodynamic therapy. Am J Gastroenterol. 100:2426–2430. 2005. View Article : Google Scholar : PubMed/NCBI

55 

Chen P, Yang T, Shi P, Shen J, Feng Q and Su J: Benefits and safety of photodynamic therapy in patients with hilar cholangiocarcinoma: A meta-analysis. Photodiagnosis Photodyn Ther. 37:1027122022. View Article : Google Scholar : PubMed/NCBI

56 

Zhou J, Xiong L, Liu W, Liu C, He C, Zou H, Wen Y and Lin L: SpyGlass-guided photodynamic therapy for unresectable cholangiocarcinoma: A case report and review of the literature. Front Oncol. 12:8907352022. View Article : Google Scholar : PubMed/NCBI

57 

Lee TY, Cheon YK and Shim CS: Photodynamic therapy in patients with advanced hilar cholangiocarcinoma: Percutaneous cholangioscopic versus peroral transpapillary approach. Photomed Laser Surg. 34:150–156. 2016. View Article : Google Scholar : PubMed/NCBI

58 

Mukai T, Yasuda I, Nakashima M, Doi S, Iwashita T, Iwata K, Kato T, Tomita E and Moriwaki H: Metallic stents are more efficacious than plastic stents in unresectable malignant hilar biliary strictures: A randomized controlled trial. J Hepatobiliary Pancreat Sci. 20:214–222. 2013. View Article : Google Scholar : PubMed/NCBI

59 

Lee TY, Cheon YK, Shim CS and Cho YD: Photodynamic therapy prolongs metal stent patency in patients with unresectable hilar cholangiocarcinoma. World J Gastroenterol. 18:5589–5594. 2012. View Article : Google Scholar : PubMed/NCBI

60 

Bae BC, Yang SG, Jeong S, Lee DH, Na K, Kim JM, Costamagna G, Kozarek RA, Isayama H, Deviere J, et al: Polymeric photosensitizer-embedded self-expanding metal stent for repeatable endoscopic photodynamic therapy of cholangiocarcinoma. Biomaterials. 35:8487–8495. 2014. View Article : Google Scholar : PubMed/NCBI

61 

Liang PC, Huang KW, Tung CC, Chang MC, Chang FY, Wong JM and Chang YT: A novel photodynamic therapy-based drug delivery system layered on a stent for treating cholangiocarcinoma. Biomed Microdevices. 20:32017. View Article : Google Scholar : PubMed/NCBI

62 

Luvira V, Satitkarnmanee E, Pugkhem A, Kietpeerakool C, Lumbiganon P and Pattanittum P: Postoperative adjuvant chemotherapy for resectable cholangiocarcinoma. Cochrane Database Syst Rev. 9:CD0128142021.PubMed/NCBI

63 

Shroff RT, Kennedy EB, Bachini M, Bekaii-Saab T, Crane C, Edeline J, El-Khoueiry A, Feng M, Katz MHG, Primrose J, et al: Adjuvant therapy for resected biliary tract cancer: ASCO clinical practice guideline. J Clin Oncol. 37:1015–1027. 2019. View Article : Google Scholar : PubMed/NCBI

64 

Nanashima A, Yamaguchi H, Shibasaki S, Ide N, Sawai T, Tsuji T, Hidaka S, Sumida Y, Nakagoe T and Nagayasu T: Adjuvant photodynamic therapy for bile duct carcinoma after surgery: A preliminary study. J Gastroenterol. 39:1095–1101. 2004. View Article : Google Scholar : PubMed/NCBI

65 

Chen Z, Jiang X, Xue P, Chen S, Li S, Li Z, Pan W and Zhang D: Long-term efficacy of percutaneous transhepatic cholangioscopy-guided photodynamic therapy for postoperative recurrent extrahepatic cholangiocarcinoma. Photodiagnosis Photodyn Ther. 40:1031222022. View Article : Google Scholar : PubMed/NCBI

66 

Wiedmann M, Caca K, Berr F, Schiefke I, Tannapfel A, Wittekind C, Mössner J, Hauss J and Witzigmann H: Neoadjuvant photodynamic therapy as a new approach to treating hilar cholangiocarcinoma: A phase II pilot study. Cancer. 97:2783–2790. 2003. View Article : Google Scholar : PubMed/NCBI

67 

Wagner A, Wiedmann M, Tannapfel A, Mayr C, Kiesslich T, Wolkersdörfer GW, Berr F, Hauss J and Witzigmann H: Neoadjuvant down-sizing of hilar cholangiocarcinoma with photodynamic therapy-long-term outcome of a phase II pilot study. Int J Mol Sci. 16:26619–2628. 2015. View Article : Google Scholar : PubMed/NCBI

68 

Cosgrove ND, Al-Osaimi AM, Sanoff HK, Morris MM, Read PW, Cox DG, Mann JA, Argo CK, Berg CL, Pelletier SJ, et al: Photodynamic therapy provides local control of cholangiocarcinoma in patients awaiting liver transplantation. Am J Transplant. 14:466–471. 2014. View Article : Google Scholar : PubMed/NCBI

69 

Kiesslich T, Wolkersdörfer G, Neureiter D, Salmhofer H and Berr F: Photodynamic therapy for non-resectable perihilar cholangiocarcinoma. Photochem Photobiol Sci. 8:23–30. 2009. View Article : Google Scholar : PubMed/NCBI

70 

Fayter D, Corbett M, Heirs M, Fox D and Eastwood A: A systematic review of photodynamic therapy in the treatment of pre-cancerous skin conditions, Barrett's oesophagus and cancers of the biliary tract, brain, head and neck, lung, oesophagus and skin. Health Technol Assess. 14:1–288. 2010. View Article : Google Scholar : PubMed/NCBI

71 

Bartusik-Aebisher D, Osuchowski M, Adamczyk M, Stopa J, Cieślar G, Kawczyk-Krupka A and Aebisher D: Advancements in photodynamic therapy of esophageal cancer. Front Oncol. 12:10245762022. View Article : Google Scholar : PubMed/NCBI

72 

Wu H, Minamide T and Yano T: Role of photodynamic therapy in the treatment of esophageal cancer. Dig Endosc. 31:508–516. 2019. View Article : Google Scholar : PubMed/NCBI

73 

Zaar O, Fougelberg J, Hermansson A, Gillstedt M, Wennberg-Larkö AM and Paoli J: Effectiveness of photodynamic therapy in Bowen's disease: A retrospective observational study in 423 lesions. J Eur Acad Dermatol Venereol. 31:1289–1294. 2017. View Article : Google Scholar : PubMed/NCBI

74 

Konopka K and Goslinski T: Photodynamic therapy in dentistry. J Dent Res. 86:694–707. 2007. View Article : Google Scholar : PubMed/NCBI

75 

Hopper C: Photodynamic therapy: A clinical reality in the treatment of cancer. Lancet Oncol. 1:212–219. 2000. View Article : Google Scholar : PubMed/NCBI

76 

Eckel F and Schmid RM: Chemotherapy in advanced biliary tract carcinoma: A pooled analysis of clinical trials. Br J Cancer. 96:896–902. 2007. View Article : Google Scholar : PubMed/NCBI

77 

Okusaka T, Nakachi K, Fukutomi A, Mizuno N, Ohkawa S, Funakoshi A, Nagino M, Kondo S, Nagaoka S, Funai J, et al: Gemcitabine alone or in combination with cisplatin in patients with biliary tract cancer: A comparative multicentre study in Japan. Br J Cancer. 103:469–474. 2010. View Article : Google Scholar : PubMed/NCBI

78 

Yang Y, Li J, Yao L and Wu L: Effect of photodynamic therapy on gemcitabine-resistant cholangiocarcinoma in vitro and in vivo Through KLF10 and EGFR. Front Cell Dev Biol. 9:7107212021. View Article : Google Scholar : PubMed/NCBI

79 

Gonzalez-Carmona MA, Bolch M, Jansen C, Vogt A, Sampels M, Mohr RU, van Beekum K, Mahn R, Praktiknjo M, Nattermann J, et al: Combined photodynamic therapy with systemic chemotherapy for unresectable cholangiocarcinoma. Aliment Pharmacol Ther. 49:437–447. 2019. View Article : Google Scholar : PubMed/NCBI

80 

Park DH, Lee SS, Park SE, Lee JL, Choi JH, Choi HJ, Jang JW, Kim HJ, Eum JB, Seo DW, et al: Randomised phase II trial of photodynamic therapy plus oral fluoropyrimidine, S-1, versus photodynamic therapy alone for unresectable hilar cholangiocarcinoma. Eur J Cancer. 50:1259–1268. 2014. View Article : Google Scholar : PubMed/NCBI

81 

Yu Y, Wang N, Wang Y, Shi Q, Yu R, Gu B, Maswikiti EP and Chen H: Photodynamic therapy combined with systemic chemotherapy for unresectable extrahepatic cholangiocarcinoma: A systematic review and meta-analysis. Photodiagnosis Photodyn Ther. 41:1033182023. View Article : Google Scholar : PubMed/NCBI

82 

Hong MJ, Cheon YK, Lee EJ, Lee TY and Shim CS: Long-term outcome of photodynamic therapy with systemic chemotherapy compared to photodynamic therapy alone in patients with advanced hilar cholangiocarcinoma. Gut Liver. 8:318–323. 2014. View Article : Google Scholar : PubMed/NCBI

83 

Liu Y, Long K, Kang W, Wang T and Wang W: Optochemical control of immune checkpoint blockade via light-triggered PD-L1 Dimerization. Advance NanoBioMed Research. 2:2200017. 2022.

84 

Bao R, Wang Y, Lai J, Zhu H, Zhao Y, Li S, Li N, Huang J, Yang Z, Wang F and Liu Z: Enhancing anti-PD-1/PD-L1 immune checkpoint inhibitory cancer therapy by CD276-targeted photodynamic ablation of tumor cells and tumor vascu lature. Mol Pharm. 16:339–348. 2019. View Article : Google Scholar : PubMed/NCBI

85 

Brackett CM and Gollnick SO: Photodynamic therapy enhancement of anti-tumor immunity. Photochem Photobiol Sci. 10:649–652. 2011. View Article : Google Scholar : PubMed/NCBI

86 

Gu X, Wu B, Feng G, Chen Z, Re F, Che X, Hong W and Li W: PD-L1 blockade peptide-modified polymeric nanoparticles for oxygen-independent-based hypoxic tumor photo/thermodynamic immunotherapy. Mol Pharm. 20:4007–4020. 2023. View Article : Google Scholar : PubMed/NCBI

87 

Bown SG, Rogowska AZ, Whitelaw DE, Lees WR, Lovat LB, Ripley P, Jones L, Wyld P, Gillams A and Hatfield AW: Photodynamic therapy for cancer of the pancreas. Gut. 50:549–557. 2002. View Article : Google Scholar : PubMed/NCBI

88 

Verigos K, Stripp DCH, Mick R, Zhu TC, Whittington R, Smith D, Dimofte A, Finlay J, Busch TM, Tochner ZA, et al: Updated results of a phase I trial of motexafin lutetium-mediated interstitial photodynamic therapy in patients with locally recurrent prostate cancer. J Environ Pathol Toxicol Oncol. 25:373–387. 2006. View Article : Google Scholar : PubMed/NCBI

89 

Beck TJ, Kreth FW, Beyer W, Mehrkens JH, Obermeier A, Stepp H, Stummer W and Baumgartner R: Interstitial photodynamic therapy of nonresectable malignant glioma recurrences using 5-aminolevulinic acid induced protoporphyrin IX. Lasers Surg Med. 39:386–393. 2007. View Article : Google Scholar : PubMed/NCBI

90 

Karakullukcu B, van Veen RL, Aans JB, Hamming-Vrieze O, Navran A, Teertstra HJ, van den Boom F, Niatsetski Y, Sterenborg HJ and Tan IB: MR and CT based treatment planning for mTHPC mediated interstitial photodynamic therapy of head and neck cancer: Description of the method. Lasers Surg Med. 45:517–523. 2013. View Article : Google Scholar : PubMed/NCBI

91 

Wang AY and Yachimski PS: Endoscopic management of pancreatobiliary neoplasms. Gastroenterology. 154:1947–1963. 2018. View Article : Google Scholar : PubMed/NCBI

92 

Soares KC, Kamel I, Cosgrove DP, Herman JM and Pawlik TM: Hilar cholangiocarcinoma: Diagnosis, treatment options, and management. Hepatobiliary Surg Nutr. 3:18–34. 2014.PubMed/NCBI

93 

Coelho-Prabhu N and Baron TH: Endoscopic retrograde cholangiopancreatography in the diagnosis and management of cholangiocarcinoma. Clin Liver Dis. 14:333–348. 2010. View Article : Google Scholar : PubMed/NCBI

94 

Lu Y, Liu L, Wu JC, Bie LK and Gong B: Efficacy and safety of photodynamic therapy for unresectable cholangiocarcinoma: A meta-analysis. Clin Res Hepatol Gastroenterol. 39:718–724. 2015. View Article : Google Scholar : PubMed/NCBI

95 

Talreja JP and Kahaleh M: Photodynamic therapy for cholangiocarcinoma. Gut Liver. 4 (Suppl 1):S62–S66. 2010. View Article : Google Scholar : PubMed/NCBI

96 

Jung CFM, Lavole J, Barret M, Ali EA, Palmieri LJ, Dermine S, Barré A, Chaussade S and Coriat R: Local therapy in advanced cholangiocarcinoma: A review of current endoscopic, medical, and oncologic treatment options. Oncology. 97l:191–201. 2019. View Article : Google Scholar : PubMed/NCBI

97 

Mohan BP, Chandan S, Khan SR, Kassab LL, Ponnada S, Artifon ELA, Otoch JP, McDonough S and Adler DG: Photodynamic therapy (PDT), radiofrequency ablation (RFA) With biliary stents in palliative treatment of unresectable extrahepatic cholangiocarcinoma: A systematic review and meta-analysis. J Clin Gastroenterol. 56:e153–e160. 2022. View Article : Google Scholar : PubMed/NCBI

98 

Buerlein RCD and Wang AY: Endoscopic retrograde cholangiopancreatography-guided ablation for cholangiocarcinoma. Gastrointest Endosc Clin N Am. 29:351–367. 2019. View Article : Google Scholar : PubMed/NCBI

99 

Killeen RP, Torreggiani WC, Malone DE and Brophy DP: Hemobilia as a potential complication in patients treated with photodynamic therapy for unresectable cholangiocarcinoma. Gastrointest Cancer Res. 3:802009.PubMed/NCBI

Related Articles

  • Abstract
  • View
  • Download
  • Twitter
Copy and paste a formatted citation
Spandidos Publications style
Li Y, Li Y, Song Y and Liu S: Advances in research and application of photodynamic therapy in cholangiocarcinoma (Review). Oncol Rep 51: 53, 2024.
APA
Li, Y., Li, Y., Song, Y., & Liu, S. (2024). Advances in research and application of photodynamic therapy in cholangiocarcinoma (Review). Oncology Reports, 51, 53. https://doi.org/10.3892/or.2024.8712
MLA
Li, Y., Li, Y., Song, Y., Liu, S."Advances in research and application of photodynamic therapy in cholangiocarcinoma (Review)". Oncology Reports 51.3 (2024): 53.
Chicago
Li, Y., Li, Y., Song, Y., Liu, S."Advances in research and application of photodynamic therapy in cholangiocarcinoma (Review)". Oncology Reports 51, no. 3 (2024): 53. https://doi.org/10.3892/or.2024.8712
Copy and paste a formatted citation
x
Spandidos Publications style
Li Y, Li Y, Song Y and Liu S: Advances in research and application of photodynamic therapy in cholangiocarcinoma (Review). Oncol Rep 51: 53, 2024.
APA
Li, Y., Li, Y., Song, Y., & Liu, S. (2024). Advances in research and application of photodynamic therapy in cholangiocarcinoma (Review). Oncology Reports, 51, 53. https://doi.org/10.3892/or.2024.8712
MLA
Li, Y., Li, Y., Song, Y., Liu, S."Advances in research and application of photodynamic therapy in cholangiocarcinoma (Review)". Oncology Reports 51.3 (2024): 53.
Chicago
Li, Y., Li, Y., Song, Y., Liu, S."Advances in research and application of photodynamic therapy in cholangiocarcinoma (Review)". Oncology Reports 51, no. 3 (2024): 53. https://doi.org/10.3892/or.2024.8712
Follow us
  • Twitter
  • LinkedIn
  • Facebook
About
  • Spandidos Publications
  • Careers
  • Cookie Policy
  • Privacy Policy
How can we help?
  • Help
  • Live Chat
  • Contact
  • Email to our Support Team