Advances in research and application of photodynamic therapy in cholangiocarcinoma (Review)

  • Authors:
    • Yufeng Li
    • Yuhang Li
    • Yinghui Song
    • Sulai Liu
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  • Published online on: February 2, 2024     https://doi.org/10.3892/or.2024.8712
  • Article Number: 53
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Abstract

Cholangiocarcinoma (CCA) is a disease characterized by insidious clinical manifestations and challenging to diagnose. Patients are usually diagnosed at an advanced stage and miss the opportunity for radical surgery. Therefore, effective palliative therapy is the main treatment approach for unresectable CCA. Current common palliative treatments include biliary drainage, chemotherapy, radiotherapy, targeted therapy and immunotherapy. However, these treatments only offer limited improvement in quality of life and survival. Photodynamic therapy (PDT) is a novel local treatment method that is considered a safe tumor ablation method for numerous cancers. It has shown good efficacy in various studies of CCA and is expected to become an important treatment for CCA. In the present study, the mechanisms of PDT in the treatment of CCA were systematically explored and the progress in the research of photosensitizers was discussed. The current study focused on the various PDT protocols and their therapeutic effects in CCA, with the objective of providing a new horizon for future research and clinical applications of PDT in the treatment of CCA.
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March-2024
Volume 51 Issue 3

Print ISSN: 1021-335X
Online ISSN:1791-2431

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Copy and paste a formatted citation
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Spandidos Publications style
Li Y, Li Y, Song Y and Liu S: Advances in research and application of photodynamic therapy in cholangiocarcinoma (Review). Oncol Rep 51: 53, 2024.
APA
Li, Y., Li, Y., Song, Y., & Liu, S. (2024). Advances in research and application of photodynamic therapy in cholangiocarcinoma (Review). Oncology Reports, 51, 53. https://doi.org/10.3892/or.2024.8712
MLA
Li, Y., Li, Y., Song, Y., Liu, S."Advances in research and application of photodynamic therapy in cholangiocarcinoma (Review)". Oncology Reports 51.3 (2024): 53.
Chicago
Li, Y., Li, Y., Song, Y., Liu, S."Advances in research and application of photodynamic therapy in cholangiocarcinoma (Review)". Oncology Reports 51, no. 3 (2024): 53. https://doi.org/10.3892/or.2024.8712